... scarcity of available data concern-ing the protective efficacy afforded by both BCG vaccination of adults and the type of vaccine strain administered precluded the inclusion of these factors as covariates ... pre-clude the estimation ofa summary protective efficacy rate. The second meta-analysis reviewed the results of 14 clinical trials and 12 case-control studies (41 ). The meta-analysts used a random-effects ... complications:estimates ofthe risks among vaccinated subjects and statistical analysis of their main char-acteristics. Adv Tuberc Res 1984;21:107–93.47. Dogliotti M. Erythema multiforme—an unusual...
... The behaviour of a- sarcin against ApA as a function of pH, altogether with the characterization of the individual pK a values ofthe active site residues, wereconsistent with the existence of ... of RNase T1 [23,26,27] and His50 of a- sarcin [20] areinvolved in catalysis rather than in substrate binding. The role of Arg77 has not yet been established as all attempts toisolate any RNase ... In RNase T1, His92 actsas the general acid and Glu58 as the general base during the first step ofthe reaction. The hydrolysis ofthe cyclicderivative is performed by the same groups, but their...
... the inevitable partial degradation of nucleolin, mean that calculations of binding affinityare unrealistic at this stage.Nucleolin localization in muscle is analogous toPTPr ligand localizationTo ... black dots, protease cleavage sites. (B) SDS ⁄ PAGEseparation of FN3d–AP purified from conditioned media using anti-placental alkaline phosphatase (PLAP) agarose. (C) SDS ⁄ PAGE and silverstain ... silverstain of proteins isolated from AP sepharose (lane 1) and FN3d–AP sepharose (lane 2). A protein band of approximately 95 kDa is presentexclusively in the FN3d–AP eluate (arrowhead). (D) Immunoblot...
... School of Medicine, Sendai, Japan3 Department of Biochemistry, Yamagata University School of Medicine, Yamagata, JapanHeme oxygenase (HO) isthe rate-limiting enzyme inheme catabolism and cleaves ... the maintenance of intracellular heme levelYongzhao Zhang1, Kazumichi Furuyama1, Kiriko Kaneko1, Yuanying Ding1, Kazuhiro Ogawa2,*,Miki Yoshizawa1, Masaki Kawamura1, Kazuhisa Takeda1, ... shibahar@mail.tains.tohoku.ac.jp*Present addressDepartment of Molecular Pharmacology,Kanazawa University Graduate School of Medical Science, Kanazawa, Japan(Received 26 January 2006, revised 5 May2006, accepted...
... Page21 chapparal changed to chaparral | | Page 22 chapparal changed to chaparral | | Page 27 chapparal changed tochaparral | | Page 28 Twigg's changed to Twiggs's | | Page 29 chapparal ... want of anofficer of rank at the head ofthe company. In the French service two captains are assigned to every company of this character, and the companies are all [well] instructed before they ... commanded the company, its train, and the generalengineer train ofthe army for more than a year. My rank was that ofSecond Lieutenant low on that list. Iwas conscious that my rank or lack of...
... that I can actually pour the vapour out ofthe flask into that basin, and set it on fire there. This, then, is exactly the same kind of vapour as we have in the middle ofthe candle; and that ... succeeding each other so fast that the eye is only able to take cognisance of them all at once. In former times, I purposely analysed a flame of that general character, and the diagram shews you the ... there is an accumulation of tallow round the cotton. In order that you may have an idea ofthe various characters of these candles, you see these which I hold in my hand they are very small, and...
... of birth, date of arrival in the Netherlands, time of diagnosis,localization of tuberculosis, country of origin, and sex. Toaccount for the fact that the reported time of immigrationwas often exactly ... adults and a signif-icantly higher rate for males than females. Except for age, the univariate incidence rate ratios were largely similar to the multivariate ratios. In univariate analysis, incidenceTuberculosis ... imputed datasets. Incidence rates were only calculated for the 2,005patients in whom tuberculosis was diagnosed more thanhalf a year after immigration because many patients with a case diagnosed...
... The pK a value of this acid–base transition is estimated based on the increase of absorbance at 418 nm aspH increases. Curve fitting ofthe fraction of thealkaline formto the calculated values ... survival of bacteriaand for causing diseases. The crystal structure of the bacterial HO (Hem O) has been reported [27]. The reaction mechanism is supposed to be analogous to those of mammalian ... Zhang2and Tadashi Yoshida21Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Japan;2Department of Biochemistry,Yamagata University School of Medicine, JapanAn...
... stirring at 1200 r.p.m. The maximalaggregation, achieved within 3 min after addition of the agonist, was determined and expressed as a percentage of 100% light transmission calibrated for each specimen(maximal ... but also for platelet activation. The rationale of this study was based on the assumptionthat peptide fragments derived from the a IIbsubunit couldact as inhibitors of platelet aggregation ... through their directinteraction with fibrinogen. The development of suchligand-binding antagonists may be advantageous against the RGD-like antagonists [20] because they could inhibitplatelet aggregation...
... an isolated thermodynamic system ΔS ≥0 ,This isa quantitative statementofthesecond law. We have expressed the secondlawofthermodynamics by an equation for entropy.and the equality sign ... build a heat enginethat converts heat completely to work, that is, an engine with 100% thermalefficiency. This impossibility isthe basis ofthefollowingstatement of Thesecondlawof thermodynamics. 2.1 ... into mechanical work, with the system ending in the samestate in which it began”.This statementis also called the Kelvin-Planck statementofthesecond law. 5/6/2008 23§4. Heat engines and refrigerators:1....
... USsavings and loans debacle ofthe 1980s, the Japanese and Swedish banking crises ofthe 1990s, the US banking crisis of 1929-33. Some of these cases (e.g. the Japanese banking crisis)illustrate ... are already clear, and whichthe FSA plans to introduceand/or which it is proposing in international fora.3Chapter 3 describes a set of wider issues raised by the crisis, and a wider set of ... innovation At the core ofthe crisis lay an interplay between macro-imbalances which had grown rapidly in the last ten years, and financial market developments and innovations which have been underwayfor...