what is the role of the respiratory system in the aerobic energy system
Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc
... processing systems.We will focus on an important linguistic aspect of polarity classification: examining the role of avariety of simple, yet under-investigated, linguis-tic knowledge sources in ... normalization.7FollowingPang et al. (2002), we use frequency as presence. In other words, the ith element of the documentvector is 1 if the corresponding unigram is present in the document and 0 otherwise. The ... accu-racy using only unigrams as features. Wethen examine the role of four types of sim-ple linguistic knowledge sources in a po-larity classification system. 1 IntroductionSentiment analysis involves...
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The Duality of Memory and Communication in the Implementation of a Multiprocessor Operating System
... advantage, the ACM copyright notice and the title of the publication andits date appear, and notice is given that copying is by permission of the Association of Computing Machinery.To copy otherwise, ... than in the inheritance case in that no sharing map is involved; an attempt to vm_write one mapping of the memory object would merely replace that mapping, rather thanreflecting it in other ... version of Mach is in use onover 200 workstations and large timesharing systems within the CMU Department of Computer Science. It is alsobeing used on dozens of machines outside the Department, including...
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Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... The tumor invades the cervical stroma (arrowhead). c DWI with b = 1,000 s/mm2shows awell-defined hyperintensity mass in the cervical area. The shape of the uterine cervix is distorted in the ... of peritoneal dissemination is rendered difficult by the poor contrast resolution vis-a-vissurrounding organs. DWI clearly discriminates the abnor-mal signal intensity of peritoneal dissemination ... controls).Further study using larger numbers of patients is neededto establish the accuracy of ADC measurement in monitoring the effect of therapy for uterine cervical cancer.For the diagnosis, McVeigh et...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches. The first approach involved measuring the level of mito-chondrial ... suggesting the importance of PKA in protein trafficking [47,48]. In this study, we usedPKA knockout mutants to determine the role of PKA in mitochondrial targeting of CYP2E1. In mutantslacking ... mitochondria-targeting signal in the yeast system. Mitochondrial localization of intact CYP2E1 in yeast cellsBecause of the existing ambiguity in the literature on the nature and extent of CYP2E1 import into...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... providedfurther insight into the molecular mechanism driving the formation of the covalent C115–fosfomycin adduct. Aconservative exchange of K22 to arginine maintains fosfo-mycin binding, while ... form of the protein. The results obtained with the K22V/R120K doublemutant protein point toward a central role of arginine 120 in the conformational process occurring during catalysis.Therefore, ... mechanism for the formation of a covalent adduct. This in turn suggeststhat UDPNAG assists in the assembly of the properinteractions in the active site by stabilizing the closedconformation of the...
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Tài liệu The Role of Public Regional Universities in Community and Economic Development doc
... assisting businesses in their provision of services to governmentCheyney UniversityDisadvantaged Business Enterprise – collaborating with business, industry and government agencies; providing ... UniversityRegional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... UniversitySmall Business Initiative in the Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new businessIndirect Contributions...
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Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf
... that the Trp169–His210 pair functions in the high catalytic activity of thisprotease at pH9 [10]. Further interest in the aromaticstacking is in the role of the electrostatic properties in enzymatic ... the pKa of His210 is 2 pH units higher than that of His57 is the buried charge interaction with Asp113. The shieldingeffect of Asp113-His210 by Trp169 was supported by the independency of the ... position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table 1 and Fig. 3A). However, the ASAs of Asp113...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... decrease in the activation energy, which results from an increasedprotein flexibility, either of the whole protein or of a specificdomain in some multidomain proteins. Furthermore,evidence from the ... importance of the Gly pair, located in the vicinity of the active site of the cold adapted enzyme and to study itspotential role in the establishment of its psychrophiliccharacter.This work uses, in ... of the model, the behavior of the G261A variant can beinterpreted in terms of constraints introduced by the Alaside chain. The presence of the additional Gly at position261 possibly offers increased...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
... DptF is GLDSV,indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) orleucine (L) in the conserved sequence. To determinewhether DptF is the ... by the C domain of the initiation module of dapto-mycin. That DptE and DptF are involved in the lipidation process of daptomycin was first shown byMiao et al. [1]. In their work, the daptomycin ... of the nonribosomally synthesized peptide is necessary.Here, we report the results of a steady-state kineticanalysis of DptE. The aim of this kinetic study was todetermine the specificity of...
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Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
... clarify the effect of the interface mutations on the antigen-binding affinity. To investigate systematically thisunsought relationship between the antigen-bindingaffinity of Fv and the VH⁄ VLinteraction ... However, as a result of covalentlinkage of the variable domains through the C-terminalconstant domains, not much is known about the distri-bution of the VH–VLinteraction strength in naturalB-cell ... to retain the specificity and affinity to antigen in itself [7,20]. Atleast for these antibodies, the role of the VLdomainmight be to increase the affinity by supporting the VHdomain. The phenomenon...
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Báo cáo khoa học: "The Role of Lexico-Semantic Feedback in Open-Domain Textual Question-Answering" ppt
... Cardie, Vincent Ng, David Pierce,Chris Buckley. Ex-amining the role of statistical and linguistic knowledgesources in a general-knowledge que stion answering sys-tem. In Proceedings of the 6th ... example, in the case of questionQ209: “Who invented the paper clip ?”, the expected answer type is PERSON and so is the subject of the verb invented , lexicalized as the nominalization inventor. ... Reims?Q-711 :What are the names of the tourist attractions in Reims?Q-712 :What do most tourists visit in Reims?Q-713 :What attracts tourists to Reims?Q-714 :What are tourist attractions in Reims?Q-715:What...
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Báo cáo " THE ROLE OF GIFT RECIPIENT PERCEPTION IN CHANGING BRAND ATTITUDES AND GIVER - RECIPIENT RELATIONSHIP " potx
... graduation. Bussey (1967), in a study in the U.K., found that the most popular occasion is Christmas, which is followed by birthday. This finding is just reverse of the finding of Belk (1973). Ruth, ... choice of gift is one of the most important decisions in the study of consumer in gift-giving behavior. Lows et al. (1971), in the British study, categorized the most relevant types of gifts ... their brand attitude, may suggest an interesting implication for the new brand advertising strategy. Instead of focusing on the content of the message which only emphasizes the benefits of...
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The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf
... predictors of wilt. Race is significant in some models (with Blacks having an advantage) but not others. Somewhat surprisingly, income is never significant. Also, when youth savings is included in the ... school. Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college. Further, when net worth is included in the model, Black youth are ... Youth savings. Youth were asked in 2002 whether they had a savings or bank account in their name. If they had an account, they were also asked whether they were saving some of this money for...
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Báo cáo khoa học: The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism pdf
... that the increase of Glc6P in the presence of S4048 was caused by the inhibition of Glc6P hydro-lysis in the absence of detectable changes in glucosephosphorylation.S4048 causes inactivation of ... control of glycolysis and glycogen synthesis by glucokinase overexpres-sion. The validity of S4048 for testing the role of Glc6P was supported byits lack of effect on glucokinase binding and ... Seoane J, Guinovart JJ &Agius L (2000) The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte. J Biol Chem 275, 10597–10603.24 Gomis RR, Cid...
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Báo cáo khoa học: The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism pdf
... mem-ber of subfamily A of family 94 (there is more about the activity of this enzyme in the accompanying mini-review by Pinot & Beisson [4]). Over 11 000 P450genes are included in this internationally ... tightbinding affinity was demonstrated towards lauric acid,resulting in the synthesis of mainly x-1 hydroxylatedlauric acid, suggesting a role in the lipid oxidativemetabolism. Interestingly, the ... biologicalfunctions. The proteins displaying the lowest similarity to the other P450s are those involved in oxylipin biosynthesis(2–6% amino acid identity). This can be explained in part by their bifunctional...
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