... are therefore 37Male Reproductive Health Disorders and the Potential Roleof Environmental Chemical Exposures the pelvis, then through the pelvis (inguinal canal) into the bottom of the ... misplaced to the edge ofthe glans or to the top of the penile shaft. In moderate cases the meatus is located lower down the shaft and in severe cases lower still and perhaps even in the perineal ... other factors in the mother – in other words, it is the lifestyle that is causal but this lifestyle also happens to increase phthalate exposure ofthe mother (for example, by heavy use of...
... turns of the DNA double helix yields binding ofthe two orthree NF-Y complexes on the same side ofthe DNA.Conservation of spacing is required for optimal pro-moter activity because changing the ... located upstream ofthe CDE-like site [46].These observations and the fact that activation doesnot rely on CCAAT-boxes, NF-Y or Sp1 proteins,leave open the question of whether the BUB1B pro-moter ... However, as in most other CDE ⁄ CHRpromoters, mutation ofthe CHR results in a smallerremaining cell cycle-regulation than alteration of the CDE [37]. Interestingly, the core ofthe human Tome-1promoter...
... cost-effective way of as-sessing health risks; the identification of all risk points along the chain of events from the origin ofthe wastewater to the consumption ofthe produce (e.g. the farm-to-fork ... products and pharmaceuticals. The impacts of these are wide-ranging. In the north east of Australia, run-off of agricultural herbicides caused the loss of 30 km2 of mangrove between 1999 and ... farm-to-fork approach ofthe HAPPC meth-od in food safety); the design of a combination of health risk management mea-sures, to be applied along the same chain of events, with the aim of ensuring health...
... vis-a`-vis the TSR the ory . On the other h and, intractability of h igh-energy intermediates suchas ferryl precludes facile experimental proof ofthe Ôtwo-stateÕ proposal owing to l ack of a ppropriate ... intermediate [11]. The sum of these findings points at the involvement of more than oneactive oxidant in the diverse types of P450-catalyzedsubstrate processing [12–15]. The g oal of t he p resent ... small alterations in the environment cancause drastic changes in the reactivity ofthe active species[76]. Further support in favour of th e idea ofthe involve-ment of a high-valent iron-oxene...
... Sciences tosecure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public. The Institute acts under the responsibil-ity ... president ofthe National Academy of Sciences. The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding ... that is the subject of this report was approved by the GoverningBoard ofthe National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National...
... appropriate, the CAQ formed a task force on theroleofthe auditor and moved to convene investors and other financial reporting stakeholders to examine the role ofthe auditor and the value ofthe ... evolve the role ofthe auditor to meet the needs of investors in the near and longer term. In the near term, the CAQ and its member firms have developed model reports for the PCAOB and other stakeholders ... CENTER FOR AUDIT QUALITY OBSERVATIONS ON THE EVOLVING ROLEOFTHE AUDITOR—A SUMMARY OF STAKEHOLDER DISCUSSIONS1IntroductionOver the years, theroleofthe public company auditor has been examined...
... PredicatesIn the spirit ofthe MRS-based analysis for the German verbs gieflen and fi,illen that we have pre-sented above, we propose that the semantic prop-erties ofthe arguments of one ofthe ... capture the semantic properties of the arguments ofthe most representative verb of the impingement predicates class in German, the verbschlagen (hit) in examples (10)-(12) above, wepropose the ... argument ofthe embedded state- of- affairs. Finally, as far as direct arguments areconcerned, in Koenig and Davis (2000) these arepredicted to link off the value ofthe KEY attribute.3.1 The verbs...
... to assume that the disruption ofthe H-bondmakes the distal His less basic. As a consequence the pKavalue ofthe NeH ofthe distal His is lowered and the rateconstant for the reaction with ... findingssuggest a similar roleofthe distal Asn-His couple in plant-type peroxidases. The present work also clearly showed that the basicity of the distal His has no impact on the reduction of organicperoxides. ... nm. The small shoulder at 368 nm indicates the presence of some free heme corresponding with the slightlyFig. 2. UV-Vis spectra ofthe ferric forms of Synechocystis wild-typeKatG and of the...
... from the rise ofthe internet and the spread of McDonalds to the establishment ofthe International Criminal Court and the emergence of global terrorism. Focusing on the implications of globalization ... have increased since the end ofthe Cold War. The end ofthe balance of power between the US and the former Soviet Union and the subsequent rise in internal strife in, among others, Africa, Europe ... activities are therefore partly directed towards these countries. Another diplomatic activity in which serving the interest ofthe city is the leading motive is the representation of cities at the EU....
... Review ofthe international roleofthe euro, Frankfurt am Main.ECB (2002), Review ofthe international roleofthe euro, Frankfurt am Main.ECB (2003a), The international roleofthe euro: ... the rest of the world. This contributes to the understanding ofthe discrepancy observedbetween the stable share ofthe euro in the bondportfolios of large international fund managers,on the ... Moreimportantly, in the course ofthe past few years, the ECB has put in the limelight three majortraits that characterise how the international role ofthe euro has unfolded so far. The first is that the euro’s...
... (Ka) for the binding of Co(II) wereobtained by fitting these data, after subtraction of the background heat of dilution, via an iterative processusing the origin software package. This software ... of 90 ± 20, 210 ± 100 and 574 ± 150 lm. The heat of reaction, measured during the experiment, wasconverted into other thermodynamic parameters using the Gibbs free energy relationship. The thermodynamicparameters ... binding of Glu97 may pre-vent binding ofthe solvent ligand that appears to bepresent in other mono-cobalt(II) species of EcMetAP-I.Combination of these data suggests that mutating the only...
... challenging than for the other oligosaccha-rides, due to the poor dispersion of signals in the 3.2–4.1 p.p.m. region ofthe spectra. Although the 1Hsignals ofthe anomeric protons ofthe 2951lgt5⁄ ... (asproposed by Edwards et al. [5]). The elucidation of the biosynthetic pathway of LOS structures of knownserotypes will allow further examination oftherole of LOS in pathogenesis. In addition, ... respectively. In the presence of active LgtA and LgtC, GlcNAc is added by LgtA.Only in the absence of LgtA can LgtC add Gal [17].From our experimental data and those of others, the roleof Lgt1–5...