steps for the medical evaluation of the obese patient
Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
... contributor for the clearance of NPs, thus the reducing rate of MPS uptake could be considered as the best strategy for prolonging the circulation of NPs (Li & Huang, 2008) Therefore, PA/EPI ... informahealthcare.com by University of Technology Sydney on 03/01/11 For personal use only Stability and in vivo evaluation of pullulan acetate 553 aqueous media The hydrophobic core of these ... respectively The bioavailability of free EPI was 100%, the BAR of PA/EPI calculated through the equation above by the AUC0–24h was 189%, much higher than the free drug According to the previous...
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Tài liệu Copper and Fiber Labeling Software and Labeling Sheets docx
... contains labels for the front and back of the hinged label SH ADCLS-TFP1RUA Adhesive label for ADC’s 2RU TFP Fiber Panel Each label sheet contains labels for the front and back of the hinged label ... sheet for left side of block SH ADCLS-NGF144SCAL Adhesive label for ADC’s 144 Fiber NGF Blocks Each label sheet contains label sheet for right side of block SH ADCLS-NGF144LCAR Adhesive label for ... sheet for left side of block SH ADCLS-NGF192LCAL Adhesive label for ADC’s 192 Fiber NGF Blocks Each label sheet contains label sheet for right side of block SH ADCLS-NGF192LCAR Adhesive label for...
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Tài liệu Stability and Control of Large-Scale Dynamical Systems pptx
... Conservation of Energy and the First Law of Thermodynamics 9.3 Nonconservation of Entropy and the Second Law of Thermodynamics 9.4 Nonconservation of Ectropy 9.5 Semistability of Discrete-Time Thermodynamic ... denote the boundary, the interior, and the closure of the set S by S, S, and S, respectively We write ã for the Euclidean vector norm, R(A) and N (A) for the range space and the null space of a ... whereas Matrosov allows for the components to be dened in the entire state space The latter formulation allows for the components of the vector Lyapunov functions to capture the whole state space...
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Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc
... been conducted by the Bank for International Settlements (the “Promisel Report”), the Bank of England, the Group of Thirty, the Of ce of the U.S Comptroller of the Currency, the Commodity Futures ... majority of both the Board of Governors of the Federal Reserve System and the Directors of the Federal Deposit Insurance Corporation as well as the secretary of the Treasury agreed Thus, the moral ... rates move in the future A party’s credit exposure, therefore, is not the notional value of the contract, as it is for a loan, but the “replacement cost” of the contract.17 Thus, the typical derivatives...
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Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... that contain the mutations, with the ˚ largest movements on the scale of A The motion is rigidbody, in the sense that the helices themselves were not perturbed The rotameric states of the internal ... some of the lessons from the de novo design of these types of proteins, which have shed considerable light on the problem of protein stability and conformational specificity [30] The a2 series of ... less clear how specific the composition of the core must be for stability and overall structural uniqueness Two limiting views of the basis of protein structure model the core of a protein as an oil...
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Đề tài " Stability and instability of the Cauchy horizon for the spherically symmetric Einstein-Maxwell-scalar field equations " doc
... one for relatively high, the other for relatively low regularity, and discuss the status of each in the context of the initial value problem of this paper and in the light of the results of Sections ... Nevertheless, Formulation of predictability seems unnatural from the point of view of both physics and the theory of partial differential equations The blow-up of the curvature or even of the C ... equations The reader can recover the full result of the proposition from the estimates for ν in Section For the slighter weaker result then, by virtue of the co-area formula, it suffices to bound the...
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Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot
... possible damage of the other disulfide bonds of the protein To demonstrate the active role of CXC motif in the oxidative folding process, we carried out the unfolding of SsMTAPII, PfPNP and their CXClacking ... improve the efficiency of the oxidative folding process Recently, on the basis of the physical properties of PDI, a variety of CXXC peptides have been synthesized and assayed [27] The active site of ... that the CXC motif is very close to the two pairs of disulfide bridges in SsMTAPII [11], further strengthens this hypothesis The data obtained in the present study represent the first example of...
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Báo cáo khoa học: Effect of flanking bases on quadruplex stability and Watson–Crick duplex competition pptx
... characteristic of the B-DNA form, and suggest the formation of duplex when complementary strands are added to a quadruplex However, they not conrm complete duplex formation for equimolar mixtures of preformed ... not the case for ank lengths of and 12 due to the presence of intramolecular stemloop structures in both the G-rich and C-rich strands The parameter that highlights the predominance of either of ... sequences at both their ends The study shows that the presence of anking bases affects the thermodynamic stability of the G-quadruplex With an increase in the ank length, the increase in the more favorable...
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Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc
... been reported in the literature For each protein, the source organism, its maximum growth temperature, the fold of the protein, the presence of cofactors, the oligomeric state, and the protein databank ... free-energy profile for the thermostable protein would be a flattened version of that for the protein from the mesophile Thus, the thermostable protein would have a more shallow dependence of DGU on temperature, ... Comparisons of the thermodynamics and kinetics of the folding of proteins from mesophilic and thermophilic ⁄ hyperthermophilic organisms can provide an insight into the mechanisms of stabilization...
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Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf
... affect the intrinsic fluorescence of the DK9 variant, the higher the surface exposure and flexibility of their side-chains to the solvent the smaller the intrinsic fluorescence of the enzyme The smaller ... expresses the acylation rate By contrast, the decrease in the DK9 Km value is consistent with better accommodation of the substrate into the catalytic pocket of the unprotonated form of the mutant, ... and the overall stability of the enzyme This investigation contributes to the unraveling of the mechanisms responsible for both the impaired catalytic activity of the K9-deleted natural mutant of...
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Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx
... capacity and entropy of formation of the TSE for folding (U-à) Reported errors reflect the quality of the nonlinear least squares fit to the experimental data We have used the F45W mutant of yeast ubiquitin ... pattern of NH–NH sequential NOEs enables us to map the extent of structure formation within the main a-helix (residues 24–33), and examine the integrity of the helix C-capping motif and of the short ... shows that the reduction in stability of these mutants is largely manifested in perturbations to the unfolding rates with the degree of compactness of the TSE (aD) and linearity of the chevron...
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Báo cáo Y học: Processing, stability, and kinetic parameters of C5a peptidase from Streptococcus pyogenes pptx
... unaffected (Fig 5C) Reduction of the intrinsic stability of the protein in the presence of EDTA and the absence of detectable stabilization effect in the presence of mM Ca2+ indicate that C5a ... and selected for the presence of the desired mutation by loss of a SpeI restriction site The presence of SerfiAla mutation at position 512 was also confirmed by sequencing the scpA gene The resultant ... temperature, 0.1 lM of the C5a peptidase in NaCl/Tris, pH 7.4 was preincubated for The reactions were started by addition of 200 lM of the 19-mer peptide to the preincubated solution of C5a peptidase...
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FINANCIAL LIBERALIZATION, MACROECONOMIC (IN)-STABILITY, AND PATTERNS OF DISTRIBUTION pptx
... target either the nominal exchange rate or the interest rate, leaving the determination of the other to the interplay of the market forces The overwhelming evidence accumulated from the developing ... and increased the vulnerability of the banking system with a high devaluation risk With the rise of the gap of the open positions of the 24 banking system, the ongoing risk premium of new borrowing ... banks The burden on the exchequer due to the liabilities of these banks as of July 2001 is estimated to be around US$ 14 billions, or 9.3% of the GNP The incidence of these operations on the productive...
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Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... was the low thermostability of the ecTRP protein, with a Tm value approximately 26 °C below the values for both sbTTR and hTTR (Fig 7) The inability of ecTRP to form fibrils at low pH can therefore ... distinguishes them from their mesophilic and thermophilic counterparts is their lower thermal stability [66] This could therefore be one explanation for the reduced stability that we observed for sbTTR ... Thr75 and His88 (hTTR numbering), buried within the hydrophobic core of the monomers The side chains of these residues form, together with the Ne1 atom of Trp79, hydrogen bonds with three or four...
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Báo cáo khoa học: Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2 pdf
... to the crystal structure for the sample in the presence of CaCl2, indicating the possibility of subtle calcium-dependent movements of the subunits, or the presence of dimeric or monomeric forms ... determined in the presence of Ca2+ The Ca rmsd between the new structure and the pre˚ vious one is 0.2–0.35 A, depending on which chains of the tetramer are compared The rmsd of Ca positions ˚ for the ... Dmax are as given by CRYSOL The theoretical I(0) was calculated for the crystal structure based on the I(0) of BSA The SAXS excluded volumes are the average volumes of the ab initio models obtained...
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power system stability and control chuong (1)
... sags 10%, then the cause of the sag is on the load side of the current monitor point If the current increases or decreases 10–20% during a 10% voltage sag, then the cause of the sag is on the source ... voltage waveforms Some machines compare portions of successive waveforms, and capture the waveform if there is a significant deviation in any portion of the waveform Others capture waveforms if there ... select the best monitor for the job, it is necessary to have an idea of the type of disturbance to be recorded, and an idea of the operating characteristics of the available disturbance analyzers For...
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power system stability and control chuong (2)
... reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use No part of this book may be ... all of the many topics encompassed by the field The chapters are written primarily for the electric power engineering professional who is seeking factual information, and secondarily for the professional ... well the authors have accomplished the goals that were set Their contributions are, of course, most key to the success of the work I gratefully acknowledge their outstanding efforts Likewise, the...
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power system stability and control chuong (3)
... when the money ran out, they were looking for other research projects The government funded a number of test turbines, from the 100 kW MOD-0 to the 2500 kW MOD-2 These ran for brief periods of ... power They therefore must cut back part of the time because of the lack of water A combination hydro and wind plant can conserve water when the wind is blowing, and use the water later, when the ... when the wind is available At a good site, the power output will be zero (or very small) for perhaps 10% of the time, rated for perhaps another 10% of the time, and at some intermediate value the...
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power system stability and control chuong (4)
... cathode through the outer circuit At the cathode the oxygen molecule interacts with the hydrogen ion and the electron from the outside circuit to form water The performance of the PEM fuel cell ... of compression per hour of generation On the other hand, the Alabama plant requires 1.7 h of compression for each hour of generation At 110-MW net output, the power ratio is 0.818 kW output for ... hours of compression required for each hour of turbine-generator operation The MW ratings and time ratio are influenced by the utility’s load curve, and the price of off-peak power For example, the...
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