... Progestins and the Mammary Gland Ernst Schering Foundation Symposium Proceedings 2007-1 Progestins and the Mammary Gland From Basic Scienceto Clinical Applications O Conneely, C Otto Editors With ... gland physiology and pathology, andto foster the interaction between basic research and drug development, the Ernst Schering Foundation held a symposium on ‘Progestins and the Mammary Gland From ... been the focus of basic and applied research for decades Steroid hormone receptors act as ligand-dependent transcription factors Upon ligand binding, the receptors bind to hormone responsive cis-acting...
... form, sector or location, are to have the potential to grow and develop so as to contribute to the overall goal To survive in the new competitive environment, no enterprise can afford to stand still ... can afford to stand still All have to be open to new ideas, new ways of working, new tools and equipment, and be able to absorb and benefit from them A policy to enhance innovation must be present ... administrative and regulatory environment is still too complex The complexity of administrative and regulatory procedures continues to be a serious obstacle to the creation of new businesses andto entrepreneurship...
... organizations and people Special thanks to my editors, Judy Umlas and Ed Levy for their contribution to making this expression clear and useful Thanks and homage to my teachers from several traditions: ... “who am I?” and cut to the core of self Thanks also to Gabriel Halpern who introduced me to Yoga andto the joy of chanting and song as a means for going beyond the intellect Thanks to N.Y Insight ... you wander from the truth 22 \ The Zen Approach™ to Project Management Stop talking and thinking and there is nothing you will not be able to know … Do not search for the truth: only cease to cherish...
... degradation and property contamination as the precursors and byproducts are introduced into homes and the outdoors Concerned individuals from many social strata have contributed to efforts to prevent ... Tijuana and Ciudad Juarez among persons ages 12 to 65 in 1998 and 2005 Use of amphetamine/ MA by males in Tijuana increased from 0.7% to 1.6%, and use by males in Juarez increased from 0.1% to 2.0% ... increased susceptibility to illness and victimization, and damage to their property Moreover, regular users often neglect their families, friends, and communities, and become burdens to society instead...
... attaching to the stomach is also called the hepatogastric ligament, and that attaching to the duodenum, the hepatoduodenal ligament In addition, peritoneal folds can extend from the liver to the ... transplantation, and mathematics in hepatology We have encouraged the use of tables and gures to aid interpretation and understanding The scientic information is current and exhaustive and is essential ... branching to the corresponding branches of the portal vein and hepatic artery, the biliary territories are considered to be identical to the portalvenous and arterial territories [30] In contrast to...
... wish to initiate RNAi and siRNA research in their own laboratories This book will also serve as a descriptive and in-depth analysis for executives, directors and scientists in Appasani research and ... of gene expression and regulation In addition, scientists have begun to take an RNomics approach to understanding the nature and function of microRNAs and siRNAs in order to utilize them as a ... tumor necrosis factor-α by both intravenous and intraperitoneal injection Appasani into mice and noted significant uptake by some organs such as the spleen Another important factor to be considered...
... academia to those working in research and development in biotechnology and pharmaceutical companies who need to understand this emerging technology From the discovery of miRNAs and their functions to ... organisms, from protozoans to humans The paradigm from the heterochromic lin-4/lin-14 genes remains the model; miRNAs have now been shown to control mRNA abundance in plants, and are thought to regulate ... microRNAs appear to be expressed throughout embryonic and larval stages and adulthood It would be interesting to extend these studies to include embryonic stages and a collection of mutant backgrounds...
... Data, and Random Access 8.1 Arrays and Vectors as Counters 8.1.1 An Introduction to the Class tvector 8.1.2 Counting with tvectors 8.2 Defining and Using tvectors ... different to a mathematician andto an accountant In computerscience conceptual ideas must often be formalized to be well understood For example, telling someone who is playing hide -and- go-seek to ... material in this book and will expand the coverage of computerscience begun here Computerscience is not just programming, and students in a first course in computerscience must be shown something...
... serotonin and vasopressin, and vasodilators such as -adrenoceptor agonists, vasoactive intestinal peptide and calcitonin generelated peptide These agents act by binding to receptors that couple to heterotrimeric ... Growth factors Vascular growth factors are potent chemoattractants and mitogens Factors such as platelet-derived growth factor (PDGF) and basic Wbroblast growth factor (bFGF) are thought to play ... estimated to bind to proteins or to be taken up into stores (Kamishima and McCarron, 1996) Despite this, opening of Ca2+ channels causes [Ca2+]i to rise to micromolar levels This is suYcient to activate...
... developing tools that will enable managers to clarify the roles of their staff in different contexts, to monitor the scopes of practice of their staff, andto detect any barrier or facilitator to effective ... management tools that divert focus away from the issue of numbers and occupational mix towards the range of roles, functions, responsibilities and activities each staff member is educated and able to ... staff-mix modifications to address organisational and system factors To support planner, policy makers and workforce planners, this article reviews the main approaches toand limitations of conventional...
... TNF receptor-associated factor 2, TRAIL – TNF-related apoptosis inducing ligand Bladder Cancer Biology 13 The export of cytochrome c into the cytoplasm and its binding to APAF1 (apoptotic peptidase ... the anti-apoptotic factor BCL2 and the pro-apoptotic factor BAX seems to act as a cellular rheostat that might be predictive for a cell’s response toward life or death after an apoptotic stimulus ... Bladder Cancer – From Basic Scienceto Robotic Surgery Another IAP – cIAP2 (BIRC3) – that regulates apoptosis by binding to the TNFR-associated factors TRAF1 and TRAF2, has been shown to provoke chemoresistance...
... THEORETICAL AND METHODOLOGICAL APPROACHES TOSOCIAL SCIENCES AND KNOWLEDGE MANAGEMENT Edited by Asunción López-Varela Theoretical and Methodological Approaches toSocial Sciences and Knowledge ... Transfers Between Social Sciences and Humanities in Relation to Natural Sciences, Technology and Government Policy 33 Hajime Eto and Shinichi Yamamoto Section Quantitative and Qualitative Approaches ... of sciences Sciences are broadly divided into natural (or physical) sciences andsocial (or human) sciences Natural sciences include disciplines such as geology, biology, meteorology Social Sciences...
... Frelin et al [42] suggest that the endothelins bind stoichiometrically to receptors, which means that most ligand molecules are bound to receptors and, therefore, cannot be determined in plasma, albeit ... midline laparotomy, ligated at a point corresponding to 35% of its average length, punctured twice with a 13-gauge needle, and compressed to extrude bowel contents into the peritoneum The abdominal ... was performed according to standard methods Experimental protocols To verify vascular paralysis, isolated blood-perfused lungs from healthy rats (n = 4) were subjected to injections of ET-1 10...
... throughout Australia, New Zealand, Papua New Guinea, Fiji, Tonga, Solomon Islands, and the Cook Islands vi Lead Author and Technical Editor Michael Gough is host and webmaster of www.SkypeTips.com, ... engineering/hacking of programs, and privacy He holds an M.S in ComputerSciencefrom Columbia University and a B.S in Computer System Engineering from Ghulam Ishaq Khan Institute of Engineering Sciences & Technology ... Directly to the Pocket PC 34 Download to Your Computerand Launch the Skype Installer 34 Download to Your Computerand Copy the Installer to Your Pocket...
... MIC and LIC countries High levels of debt and inflation expand the lead times to production Column (2) shows that high levels of debt and inflation lengthen the lead time to production by 16 and ... discovery and production, investment growth rises sharply and vulnerabilities can increase Growth can become vulnerable to setbacks in mining sectors A Share of non-ferrous discoveries converted into ... Lead times to production depend on a wide range of technical, economic, social, and political factors They include the accessibility and quality of the discovery, commodity prices, and policy...
... chief among these will be to separate fantasy from reality and leverage the practical benefits of IT in order to provide social actors with the ability to communicate andto share knowledge-informing ... the development, implementation and use of systems to informate organizational actors and automate business processes (Checkland and Howell, 1998) However, Boland et al (1994) argue that information ... had to capture the technical understanding of application engineers and relate this to Analog’s products and their attributes in order to build cases for the KATE-Tools platform This activity took...
... store in Orbetello, Italy and taken backto New York, where they were cast and stacked on top 6f each other Originally, the stack was six vases high,10 but later it was cut and transformed into ... of the mould from the Orbetello vases finds itself called to a new life and cast again atop a long pole in OTTO, 1982, which spelled backwards is still OTTO11 This lack of front or back, or the ... Basquiat and mutual friends and acquaintances The film creates a past as a touching tribute, but never strays too far from Schnabel’s own experience Basquiat allows him to retell some of the C.V.J story...
... identity and ‘voice’ xxv FROMSOCIAL SILENCE TOSOCIALSCIENCE Chapter by Mandisa Mbali provides a detailed and cogent socio-historical analysis of how HIV/AIDS entered into a complex same-sex social ... into safe and unsafe sex practices in relation to the socialFROMSOCIAL SILENCE TOSOCIALSCIENCE position of different groups and in the context of other health behaviours, such as alcohol and ... general and as it relates to HIV/AIDS; 2) to identify research needs and priorities related to same-sex sexual practices and HIV/AIDS; and 3) to explore challenges and potential solutions to research...
... follow-up (0 to 14, 15 to 29, 30 to 34, 35 to 39, 40 to 44, 45 to 49, 50 to 54, 55 to 59, 60 to 64, 65 to 69 and 70+) and calendar period of follow-up (1961 to 1965, , 2001 to 2005, 2006 to 2007 Case ... 0.96 (0.92 to 1.01) Denmark 332 963 0.99 (0.89 to 1.11) 1.01 (0.86 to 1.19) Estonia 144 329 0.97 (0.82 to 1.14) 1.34 (0.96 to 1.89) Finland 830 3,920 0.94 (0.88 to 1.01) 0.98 (0.90 to 1.07) Latvia ... (0.65 to 1.53) Poland 66 349 0.88 (0.69 to 1.12) 1.09 (0.84 to 1.42) Soviet Union† Other 96 10 171 60 1.15 (0.94 to 1.40) 1.22 (0.66 to 2.28) 1.14 (0.87 to 1.49) 1.20 (0.62 to 2.33) 1.01 (0.95 to...
... determined to continue to give priority to SMEs andto take into account their specific characteristics in its proposals and programmes Improving the awareness and visibility of actions with national and ... governments and business organizations to contribute to evaluating and reporting on the uptake of the SBA, to step up efforts to disseminate widely information on SME-policy actions andto promote ... decision to increase the period of public consultations launched by the Commission from eight to twelve weeks from 2012 onwards should give more time to stakeholders to consult their members and to...