... butkeeping the NADPH concentration constant at nonsat-urating (10 lm) and saturating (1 mm) levels of NADPH and varying the biliverdin concentration inthe range 0.5–10 lm. A concentration of 1 mm wasused ... of sBVR-A and to conductthese experiments under a range of conditions, includ-ing temperature, pH and the presence or absence of phosphate, because this has such a pronounced activat-ing effect ... be associated with anionizing residue that is involved in binding the 2¢-phos-phate of NADPH.The effectofpHon the initial rate kinetics is consis-tent with two ionizing groups in the enzyme...
... role in the activation of PLD.Functional role of PLD-derived second messengersTo determine the extent to which the activation of neutrophil functional responses was dependent on individ-ual PtdCho-derived ... Priming of human neutrophil superoxidegeneration by tumour necrosis factor-alpha is signalled byenhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol1,4,5-trisphosphate accumulation. ... viability of cells, as assessedby trypan blue exclusion, was >97% and the purity of neutrophil preparations was routinely >96% with <0.1%mononuclear cell contamination.Measurement of degranulationAgonist-stimulated...
... accountsfor the effectofpHof exposure, 24% of thevariation was described. Adding the term whichaccounts for the effectofpHof acclimation de-scribed 36% of the variation in zinc uptake. Consid-ering ... the effect of the pHof acclimation (pH accl) described38% of the variation in cadmium uptake. Consid-ering only the results of the cadmium uptakeexperiments performed at the pHof acclimation(i.e. ... analy-sis of variance of the data showed that both the effect of the pHof exposure and the pH of acclimation on Cd uptake are highly significant(Table 2a).Fig. 3 shows the results of the effect of...
... counteracting long-range electrostaticinteractions that would otherwise act as destabilizingforces for native-like conformations.ConclusionsThe comparison of apo- and holo-lMb by MD simu-lations reveals ... betaken as a model of an unstable intermediate in holo-lMb unfolding on loss of the cofactor. The MD simu-lation results provide an explanation of why such aconformation is not a stable state ... Journal compilation ª 2007 FEBS 93The effectof heme on the conformational stability of micro-myoglobinHong-Fang Ji1,2, Liang Shen1,2, Rita Grandori3and Norbert Mu¨ller21 Shandong Provincial...
... days. Effects on total days for each variable were calculated by multiplying three parts: the effecton the probability of a year with at least one day, the mean effecton days conditional on ... construction. Proof that the first order Taylor series approximation to the confidence intervals is a good assumption for the logistic reduction in years with a hospitalization. The log of ... standard deviation of the coefficient in the original equation to the standard deviation of the impact on population probabilities. For example, a listed standard error of 0.0098 on the logit is...
... Canada.2Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S3M2, Canada.Authors’ contributionsAll authors have ... F: Effectof cimetidine on renal function in normal man. Clin Pharmacol Ther 1978, 24:76-83.15. Dutt MK, Moody P, Northfield TC: Effectof cimetidine on renal function inman. Br J Clin Pharmacol ... Journal of Translational Medicine 2010, 8:139http://www.translational-medicine.com/content/8/1/139Page 8 of 11RESEARC H Open AccessThe effectof acyclovir on the tubular secretion of creatinine...
... theproblem of variations across households to the more institutional issue of the relationship between the political mobilization of classes on theone hand and gender relations on the other. One might ... gender relationsare not mere functions of class or anything else, and in this sense theyhave some genuine autonomy.An implication of relatively strong versions of the gender-autonomythesis ... compositions.Class counts150tion of housework ± to the contrast between highly egalitarian andinegalitarian households ± rather than to the distribution as a whole.None of these manipulations of...
... combination of text and visuals elicits beneficial effects in terms of comprehension of the material. Visuals not only offer additional contextual information to facilitate comprehension, perhaps ... significantly better on the translation task because the inclusion of pictures with the text provided readers with two sources of information instead of one. The positive effectof pictures on reading ... text’s content. Some examples of visuals are pictures, photos, maps, diagrams, charts, animations, and cartoons. In one study on reading comprehension, Tang [13] asked one group of seventh-grade...
... (2002) Effects of maternal exposure to a reconstituted mixture of polychlorinated biphenyls on sex-dependent behaviours and steroid hormone concentrations in rats: dose-response relationship. ... Accurate prediction of the response of freshwater sh to a mixture of estrogenic chemicals. Environ Health Perspect., 113(6):721-728. 42EFFECTS OF POLLUTANTS ON THE REPRODUCTIVE HEALTH OF MALE VERTEBRATE ... M., et al. (2006) Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age. Environ Health Perspect.,114(2):270-276....
... Landapplication of biosolids: comparison among stabilization methods.In: Wilson, T.E. (Ed.), Water Resources and the Urban Environ-ment-98, Proceedings of the (1998) National Conference on Environmental ... elevated Mo concentrations in Hudson soilcolumns, particularly in the pH 7 columns.P concentrations (Fig. 9) declined over the course of operation. The greatest concentrations observed duringthe ... pelletized sludge on Hud-son soils, but concentrations were generally indis-tinguishable from control levels. Percolate S wereelevated in pH 5 Hudson soils due to acid additionsduring pH adjustments...
... infusion, respectively. Effect of DEX on VNR-induced phlebitis A 0.6-mg/mL solution of VNR was infused over 30 min at 5 mL/kg/hr into the ear vein. To clarify the effect of DEX on phlebitis ... procedure The effects of rapid infusion and dilution of the injection solution on phlebitis caused by VNR was evaluated in a rabbit model, as reported elsewhere [4]. Briefly, test solutions of VNR ... infu-sion, the veins were evaluated histopathologically. The effectof DEX on VNR-induced phlebitis was evaluated by infusion of DEX before or after VNR. The effectof PSL on DXR-induced phlebitis...
... antibody concentration. The number of mature liver schizonts increased up to 150% in the presence of mAbs anti-CSP of P. yoelii, which were suppressive at higher concentrations. Contradictory effects ... inhibitory effect [7]. The number of mature liver schizonts increased in the presence of mAbs anti-CSP of P. yoelii and the authors suggested that enhancement of infection could be a consequence of ... important role in the control of malaria infection. However, they can modulate parasite development enhancing infection. The effectof anti-Plasmodium antibodies on the expression of circumsporozoite...