Comparative genetic analysis of the transcriptional regulatory DNA of the oxytocin and vasopressin genes

... peptides, and the structure and evolution of the genes encoding them Then I discuss the known characteristics of regulatory DNA, and the approaches used to identify and characterize regulatory DNA, ... between the modern oxytocin and vasopressin enhancers 1.2 Structure of oxytocin and vasopressin related genes The genes encoding oxytocin and vasopressin are homologous in the sequence and organization ... on oxytocin and vasopressin gene expression An understanding of the neuroendocrine role of oxytocin and vasopressin requires an understanding of how oxytocin and vasopressin are expressed in the...

Genetic analysis of SNPs in and around the MDRI gene locus

... examined in this thesis, the MDR1, MDR3 genes and the CYP3A cluster are introduced Previous genetic and pharmacogenetics studies on these candidate genes are also reviewed in this section Finally, ... association study of phenotypic changes and their corresponding genetic variants strongly relies on the understanding of Linkage Disequilibrium On the one hand, the linkage between genetic polymorphisms ... identification of genetic variants that control drug-response remains the central problem of the modern Pharmacogenetics The natural history of genetic polymorphisms in the human genome provides the most...

Báo cáo y học: "Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora" ppt

... linkage map (L13 and L14) of the reef-building coral A millepora A genetic linkage map (L13 and L14) of the reef-building coral A millepora Female (F) and male (M) maps are shown on the left and ... cM) and represents the first linkage map for a coral, as well as for any non-bilaterian multicellular organism The map will become the foundation for QTL analysis of adaptive traits and population ... of the Bilateria Anthozoan cnidarians such as corals are phylogenetically basal in the phylum Cnidaria, and have proven to be particularly informative for understanding the evolution of metazoan...

Báo cáo khoa học: Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria pptx

... indicating the somewhat increased ¯exibility of the proteinase- binding loop compared to the rest of the molecules agree well with the ®ndings obtained from recently determined NMR structures of other proteinase ... Cys27 These data together with the calculated structures are indicative of a number of intersheet hydrogen bonds in both of the molecules The exchanging properties of the amide protons of SGCI[L30R, ... Furthermore, the results of the H±D exchange experiment suggest a signi®cant difference in the internal ¯exibility of the molecules The rigid nature of the second b strand is consistent with the...

báo cáo khoa học: "Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias (Streptophyta), with emphasis on the role of expansin" pot

... participated in the synchronization and RNA-extraction and in the interpretation of the data JG and LDV participated in the design of the experiments DI and WV conceived and supervised the study ... Vannerum et al.: Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias (Streptophyta), with emphasis on the role of expansin BMC Plant Biology 2011 ... http://www.biomedcentral.com/1471-2229/11/128 of the evolution of genes involved in cell wall formation in green algae and land plants Cell walls have played crucial roles in the colonization of land by plants [63,64]...

Báo cáo y học: " Comparative genomic analysis of bacteriophages specific to the channel catfish pathogen Edwardsiella ictaluri" pptx

... initiated to examine the potential of these three bacteriophages for lysogeny, to ensure they did not harbor virulence or toxin genes and to better understand the genetic basis of their host specificity ... Carrias et al.: Comparative genomic analysis of bacteriophages specific to the channel catfish pathogen Edwardsiella ictaluri Virology Journal 2011 8:6 Submit your next manuscript to BioMed Central ... without the capacity for lysogeny Additionally, none of the predicted proteins have similarities to known bacterial pathogenicity factors These observations indicate that these phages lack any lysogenic...

Báo cáo y học: "Comparative genomic analysis of the Tribolium immune system" pps

... components of the innate immune system are hardly known in T castaneum and neither is it clear how they differ from homologous molecules in the honeybee, mosquito or fruitfly [6,7,18] This lack of knowledge ... immunity is conserved in the beetle Furthermore, the modulation of these pathways may also resemble each other - we have identified putative 1:1 orthologs of IAP2, Tab2 and caspar in the Tribolium ... A Figure Expansion of the clip-domain family of SPs and SPHs in the T castaneum genome Expansion of the clip-domain family of SPs and SPHs in the T castaneum genome The catalytic and proteinase-like...

Báo cáo sinh học: "Molecular genetic analysis of a cattle population to reconstitute the extinct Algarvia breed" pptx

... AG35 and AG36), Limousin (AG23, AG32, AG37, AG39 and AG41) and Mertolenga breeds (AG12 and AG17) For the Algarvia population, the average value of Q was 0.85 ± 0.27 and was the lowest among all ... Garvonesa, two Mertolenga and one Preta individuals Two Algarvia animals (AG40 and AG43) and one Garvonesa shared a T 1a haplotype Interestingly, a T 1a haplotype found in one Algarvia (AG16) and three ... Page of 11 mals, the related southern breeds (Alentejana, Garvonesa, Mertolenga and Preta) and the Limousin cattle to determine which Algarvia animals clustered as an independent group, and to...

Báo cáo sinh học: "Use of the score test as a goodness-of-ﬁt measure of the covariance structure in genetic analysis of longitudinal data" ppt

... improvement in the t of the environmental covariance was obtained when relaxing the assumption of constant residual variance, and was clearly shown in the score statistic values A much simpler model was ... parameters on the sub-diagonals and D is a diagonal matrix of the inverse of innovation variances Score and information matrices for D and L parameters can be calculated as functions of the rst and second ... environmental variance to the data whereas the previous score statistic (T r ) was a goodness -of- t measure for the environmental variance assuming all the other covariance parameters to be perfectly...

Báo cáo sinh học: "Cumulative t-link threshold models for the genetic analysis of calving ease scores" pptx

... densities or products thereof may be specified for the prior density p(ϕ) on ϕ, depending, again, on the number of sets of random effects and whether there are any covariances thereof [21] Finally, ... CT models used for the analysis of calving ease data included the fixed effects of age of dam classifications, sex of calf and their interaction in β, the random effects of independent herd-yearseason ... from the two populations, comparing the CP versus CT models for the analysis of ordinal categorical data and comparing the Gaussian linear mixed model versus the t-error linear mixed model for the...

Báo cáo sinh học: "A genetic analysis of variable number of tandem repeats (VNTR) polymorphism in the horse potx

... determine the number of loci controlling the fragment polymorphism One is based on the analysis of the relative segregation of paternal fragments in their progeny, the other considers that, in the ... tandemly repeated Initially, highly polymorphic patterns displaying a large number of fragments on Southern blots resulting from variation in the number of tandem repeats and called fingerprints ... animals were interrelated, thus reducing the variability observed in unrelated animals of the same breed In spite of some limits imposed by the resolution of the technique, the high polymorphism...

Báo cáo y học: "Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map" doc

... with the physical and genetic maps of Trypanosoma brucei brucei Comparison Comparison with the physical and genetic maps of Trypanosoma brucei brucei The genetic maps of T b brucei isolate TREU ... the salivary glands (transmission index), and in their ability to resist killing by a number of trypanocidal drugs used in the treatment of human African trypanosomiasis [18] The availability ... Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which are the cause of sleeping sickness in humans; and the nonhuman infective Trypanosoma brucei brucei subspecies Over the past...

Genetic analysis of the role of ARP2 3 complex in border cell migration in drosophila melanogaster

... polyproline sequences and interacts with profilin (Chang et al 1997) Since profilin binds to actin monomer, FH1 domains can bind the profilin-G-actin 13 Arp2/ 3 complex in border cell migration ... actin assembly In Drosophila, the Arp2/ 3 complex functions in actin dynamics together with SCAR/WAVE and WASP proteins The Drosophila Arp2/ 3 complex and SCAR/WAVE 22 Arp2/ 3 complex in border cell ... 1996) 36 Arp2/ 3 complex in border cell migration Lu Ruifeng 2010 The most obvious feature of the Mbm protein is a pair of C2HC zinc fingers, implicating a function of the protein in binding nucleic...

A multiplex comparative proteomic analysis of hypoxia influence in the presence and absence of p53 in HCT116 cells

... Other kinases, such as casein kinase I and II, protein kinase A, 38 CDK7, DNA-activated protein kinase, and Jun-NH2 kinase (JNK), also mediate phosphorylation of p53 and play important roles in ... that in turn “protects” radiation-damaged DNA from restoring to an undamaged state Stable DNA damage accumulates and leads to an increased lethality from a given dose of radiation in cells, inducing ... criteria 4.3 Top funcitons and diseases identified by IPA 76 4.4 Tabulation of common proteins regulated in cells under 81 hypoxia in the presence and absence of p53 as well as in the absence of p53...

Comparative analysis of english formal and informal correspondence

... newspapers mainly employ a colloquial or informal style Kinds of correspondence There are two main kinds of correspondence: formal and informal ones 3.1 Formal letters .Formal letters are used for serious ... Contrastive and comparative method * Analysis and systematic method • Obtaining advice from experts IV Scope of the study • Due to the time limitation, we only focus on English formal and informal correspondence ... help us define and identify registers Our analysis of informal and formal correspondence produces the following results: 1.3 Use of vocabulary According to G.B Antrughiha et.al, informal words...

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