which hormone is responsible for controlling blood sugar levels
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... of carnitine: mm (for standard comparison with other published data), and a concentration equal to the Km for carnitine of each enzyme (for comparison between mutants) In this article, we show ... been dissected in the N-terminal region of this enzyme, which is less malonyl-CoA sensitive than human CPT1B The IC50 for malonyl-CoA inhibition of human CPT1B (IC50 = 0.096 lm) [7,22,23] is ... sequence as being responsible for the peculiar kinetic characteristics of this enzyme, acting as a negative determinant for malonyl-CoA sensitivity Asp17 may account, at least in part, for the high...
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Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
... the active conformation, Val371 forms contacts with neighboring residues that are important for stabilizing the active state (e.g Asp189, which is part of the S1 pocket responsible for the binding ... sequence identity of 3045%), this position is occupied solely by a valine This conserved amino acid is replaced by isoleucine in the Val371Ile FXI mutant Interestingly, an isoleucine residue naturally ... levels and hemorrhagic episodes are usually associated with injury or surgery, but may be so severe as to demand replacement therapy [16] The genetic basis of this rare coagulation disorder is...
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Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
... However, this proteolysis is much slower in vitro, because of a lack of chaperone machinery The in vitro proteolysis requires ATP [14] We examined the proteolysis of purified r32-C-his (1.2 lm) ... several membrane-associated substrates, for which the mechanism of proteolysis is probably somewhat different [21] Whether kCIII would act as an inhibitor for such substrates (e.g SecY, YccA, Foa) ... CIII on proteolysis of the heat shock sigma factor r32, another substrate of HflB Like proteolysis of CII, r32 proteolysis requires ATP Both CIII and CIIIC inhibit this proteolysis, with CIIIC exhibiting...
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Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf
... synthesis, it might be involved in the stearic acid incorporation after the de novo synthesis of this lipid (i.e the second hypothesis) According to this hypothesis, previously raised for mammals ... throughout eukaryotes, and the biosynthetic pathway for PI synthesis is well documented [14] PI is synthesized from phosphatidic acid (PA), which is further used as substrate by a cytidine diphosphate-diacylglycerol ... regulation [1–5] The fatty acid composition of this phospholipid is quite distinctive in living organisms because, in comparison with other phospholipids, PI is by far the most saturated In bovine heart,...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... ABCG2R482G remains in a conformation that contains a low-affinity binding site for [3H]daunomycin immediately post-nucleotide hydrolysis Discussion A precise molecular mechanism for substrate translocation ... low-affinity conformation of drug binding sites in ABC multidrug efflux pumps is assumed to correspond to the outward-facing conformation The energy produced by the hydrolysis of ATP is harnessed for the ... binding affinity for [a32P]azido-ATP as KD = 201 ± 80 lm This affinity is similar to the value obtained for ATP binding to ABCB1 [29] The ability of nucleotides to displace binding is shown in Fig...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... hydrolysis), corresponding to that expected for the F variant This result is the first evidence for the heterozygous status (M/F) of the individual goat milk analysed In addition to this, the ... first one is an ACRS-PCR technique [26], the principle of which is to create a TaqI restriction site (TCGA) by using a mismatching primer (C9LM*) which allows both the F and M alleles to be discriminated ... subsequently distinguished after a second amplification which allows discrimination between the alleles on the basis of the fragment sizes (Fig 8, Step IIA) In the first step, a 266-bp (265 bp for the...
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Which Sound Is Different?
... A schwa B scheme C skeptical D schematic A bronchitis B chestnut C chronometer D chrisma A chauvinism B exchange C teacher D childrearing A bristle B indict C Connecticut D Vinci 10 A scherzo ... complexity A exceed 10 A Marxism B approximate B axis C fix B exist B exhibition B fixture B exert B excerpt B complexion B oxen B tax C anxiety D fox D boxing C exhaust D exercise C exaggerate D exam ... 10 A loose B geologist B tough B information B put B enough B blood B collaborate B mostly B shoes B cooperation C horizon D gallop C through D much C favor D form C would D could C thorough D...
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Which Sound Is Different?
... A schwa B scheme C skeptical D schematic A bronchitis B chestnut C chronometer D chrisma A chauvinism B exchange C teacher D childrearing A bristle B indict C Connecticut D Vinci 10 A scherzo ... complexity A exceed 10 A Marxism B approximate B axis C fix B exist B exhibition B fixture B exert B excerpt B complexion B oxen B tax C anxiety D fox D boxing C exhaust D exercise C exaggerate D exam ... exciting A complexity A exceed 10 A Marxism B axis B exist B exhibition B fixture B exert B excerpt B complexion B oxen B tax C fix D boxing C exhaust D exercise C exaggerate D exam C chickenpox...
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What is the question to which ‘substitution’ is the answer
... that either one is responsible for everything or one has refused responsibility This is how Levinas answers those who say that to be responsible for everything is to be responsible for nothing In ... on this account, but that does not mean that the relation to being in which the ethical is situated is not crucial This is why it is not irrelevant what is said in the saying, just as it is not ... Infinity is that it is only for an already established ‘I’ that the other arises The separated I, the subject, is put in question by the other but it is only with the somewhat problematic analysis...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25