the treatment of class ii malocclusion—have we the evidence to make decisions
Báo cáo sinh học: "The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" pdf
... to both metabolic inhibitors (3BrP and IA) decreased as the bioenergetic signature of the cells increased Thus, the lower the bioenergetic signature of a cell the greater the death response to ... activation of caspase (an apoptotic indicator) was observed following any of these above treatments in any of the cell lines tested (data not shown) Therefore, inhibition of the activity of glycolytic ... to the glycolytic inhibitor treatment (G > M > SM) (Figure 1D) In fact, significant inverse correlations Page of were uncovered between the bioenergetic signature of a cell and the extent of...
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báo cáo hóa học:" The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil" ppt
... to both metabolic inhibitors (3BrP and IA) decreased as the bioenergetic signature of the cells increased Thus, the lower the bioenergetic signature of a cell the greater the death response to ... activation of caspase (an apoptotic indicator) was observed following any of these above treatments in any of the cell lines tested (data not shown) Therefore, inhibition of the activity of glycolytic ... to the glycolytic inhibitor treatment (G > M > SM) (Figure 1D) In fact, significant inverse correlations Page of were uncovered between the bioenergetic signature of a cell and the extent of...
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Báo cáo y học: "Five-year follow-up of Japanese patients with Paget''''s disease of the bone after treatment with low-dose oral alendronate: a case series/" ppt
... to be more suitable for the treatment of Japanese patients since the dose of alendronate used for the treatment of osteoporosis in Japanese patients (5 mg per day) was half of that used for the ... for the treatment of osteoporosis in Caucasians (10 mg per day) Thereafter, we reported that the therapeutic efficacy of this treatment was equivalent to that of a high Iba et al Journal of Medical ... changes in the left acetabulum, half of the ilium, and the pubic bone dosage of alendronate for one year after the cessation of treatment [9] Furthermore, in this study, we have shown that the administration...
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Báo cáo y học: "Cost estimates of HIV care and treatment with and without anti-retroviral therapy at Arba Minch Hospital in southern Ethiopia" docx
... identification of inputs and their valuations It also provides an overview of the cost profile of different components of an intervention, and the total amount of resources needed to sustain or ... corresponding costs were calculated as ratios of the frequencies of use of each service to the total PYO In estimating inpatient costs, we evaluated annual use of inpatient services for the 58 HIV patients ... 1Overhead costs were calculated by dividing the total laboratory overhead cost by the total number of laboratory tests during the base year The recurrent and capital unit overhead costs therefore remained...
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Báo cáo y học: "Insect sting allergy. A study from 1980 to 2003 of patients who started treatment with venom immunotherapy between 1980 and 1998" pps
... symptoms, angioedema of the head and neck or symptoms from two organ systems, to a sting from bee and/or wasp and who were willing to comply with a minimum of five years of treatment were offered ... performed and the majority of patients feel substantially safer Most of them found the effort very worthwhile We should endeavour to get more of the patients to complete five years of IT as the results ... swelling of joints was related to the injections disappearing later but sometimes steroids were given to alleviate the symptoms In other cases rheumatoid arthritis or osteoarthritis proved to...
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TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS
... activity of the mammalian target of rapamycin (mTOR) is a major inhibitor of the progression of apoptosis, and stability of mitochondrial function may result from PINK-1-induced upregulation of Akt ... implantation of the cells avoids not only the cytotoxic environment of the acute injury epicenter, but also allows for the development of cystic cavities in which to inject the cells into Even still, ... contrast to an upregulation of autophagy and autophagosome production As such, the matter of whether injury increases autophagy, or autophagy exacerbates injury is still debated Nonetheless, autophagic...
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Tài liệu Báo cáo Y học: Proteolysis of bovine b-lactoglobulin during thermal treatment in subdenaturing conditions highlights some structural features of the temperature-modified protein and yields fragments with low immunoreactivity pptx
... water bath thermostatted at 60 °C for the given amount of time At the end of the heat treatment the mixtures were placed on ice, and the enzymatic activity was stopped by adding 0.2 mL of 50% (v/v) ... of : 20 or of : 10 The protein/protease mixture was then placed in a thermostatted water bath for the required amount of time At the end of the heat treatment the mixtures were placed in an ice/water ... ice/water bath, and the enzymatic activity was stopped by lowering the pH of the reaction mixture to by addition of 0.2 mL of 50% (v/v) acetic acid in water All these manipulations were carried out...
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báo cáo hóa học: " Comparison of the discriminative ability of a generic and a condition-specific OHRQoL measure in adolescents with and without normative need for orthodontic treatment" potx
... defects of cleft lip and palate as well as any craniofacial anomaly, Class II and Class III buccal occlusions, and hypodontia Only the highest scoring trait is used to assess treatment need [29] Thereafter, ... self-rated their dental attractiveness on the 10-point scale of the Aesthetic Component (AC) of IOTN [29,30] Results from DHC and AC of IOTN were merged into a single classification according to the ... differed according to the indicator used to assess the impacts of oral conditions on participants' quality of life (the overall score or the prevalence of oral impacts) or the index used to define normative...
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báo cáo hóa học:" Health-related quality of life in relapsing remitting multiple sclerosis patients during treatment with glatiramer acetate: a prospective, observational, international, multi-centre study" pdf
... initiated the study, contributed to conception and design of the study, acquisition of data, analysis of data and interpretation of data, drafted the manuscript, and has given final approval of the ... the past month and consists of a total of 40 questions in domains: cognitive, physical and social Answers are rated on a 5-point scale (0 to 4) Total FIS score ranges from to 160 and higher total ... centers in the Netherlands, Sweden and Belgium The protocol was submitted to the Independent Review Board (IRB), an approved ethical committee residing in Amsterdam, the Netherlands The IRB concluded...
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Báo cáo y học: "Residual sleep disturbance and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine" docx
... http://www.annals-general-psychiatry.com/content/9/1/10 weeks Target fluoxetine dosages were 10 mg/day for the first week, 20 mg/day for weeks to 4, 40 mg/day for weeks to 8, and 60 mg/day for weeks to 12 The dose was increased to meet the target ... reason, there is the need for more studies specifically examining the role of residual sleep disturbance as a predictor of relapse in MDD Therefore, the purpose of the present study was to explore the ... or to switch to placebo (n = 131) for 52 weeks or until relapse Patients were seen monthly for the duration of the 52-week trial By convention, the first months of this period were considered the...
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Báo cáo y học: " Predictors of infusion reactions during infliximab treatment in patients with arthritis" docx
... interpretation, and wrote the manuscript LL contributed to the collection of data, its interpretation and preparation of the manuscript GS contributed to the idea and to the critical revision of the article ... includes an overview of the studies investigating autoantibody profile during treatment with infliximab, ANAs were detected in between 4% and 17% of SpA patients before initiation of treatment One possible ... between new appearances of ANAs during infliximab treatment and the clinical consequences of these have been addressed in several studies [7-11] However, to our knowledge, the present study is the...
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Báo cáo y học: " The potential role of appetite in predicting weight changes during treatment with olanzapine" ppt
... d) between overall weight change and 2-week appetite scale changes, adjusted by 2-week weight change (the correlation of appetite changes on the residuals from the regression of endpoint weight ... showed that there is no weight gain in female rats in the absence of hyperphagia [24] Another reason for the inconsistency of our observations might be the possibility that weight gain during treatment ... Coefficients between overall weight change and 2-week appetite scale changes, adjusted by 2-week weight change (the correlation of appetite changes on the residuals from the regression of endpoint weight...
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Báo cáo y học: " Impact of race on efficacy and safety during treatment with olanzapine in schizophrenia, schizophreniform or schizoaffective disorde" pdf
... looked at the impact of race on the efficacy and safety of long-acting risperidone compared to placebo [26] These results showed there was no effect of race on the improvement of PANSS total scores ... shows similar patterns of symptoms across populations The overall prevalence of schizophrenia is estimated to be between 1% to 2% of the population, and the prevalence of major psychotic disorders ... seen for the remainder of the analysis Given recent attention to the outcome of all-cause time to discontinuation in the treatment of schizophrenia as a proxy measure for treatment effectiveness...
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Báo cáo y học: " Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment" ppt
... DNA were tested every 12 weeks during the telbivudine therapy Healthy donors (n = 10) were included as controls The Wilcoxon matched pairs test and the Mann-Whitney test of SPSS version 12.0 were ... Fig 1b To determine whether the decreased percentage of CD8 + CD127 + memory T cells reflected an absolute reduction of these cells or increase of CD8 + CD127 memory T cells, we calculated the absolute ... as ‘non-responders’ The other ten patients were defined as ‘partial responders’ We dynamically compared the proportion of CD127 expression on the memory CD8 T cells among the well responders, partial...
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Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
... response to therapy was shown not to be optimal, we were interested to know whether this effect also applied to diseases that showed a good clinical response Therefore, we aimed to determine the effect ... whether the observed changes were related to the magnitude of IFN response gene expression prior to treatment Therefore, the relationship between the extent of the baseline IFN response gene expression ... response to treatment Finally, we investigated whether the treatment- induced changes in type I IFN response gene expression levels were associated with clinical response to treatment Therefore, the...
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Báo cáo y học: "Endovascular Treatment of Bilateral Carotid Artery Occlusion with Concurrent Basilar"
... scan showed that the hemorrhage was localized on the pontine cistern and interpeduncular cistern, extending to the right of the ambient cistern into the posterior horn of the right ventricle The ... Occlusion Begnning of the CCA Begnning of the CCA Begnning of the ICA Left cavernous sinus part of the ICA, right beginning of the ICA Begnning of the ICA Symptom Other aeurysms SAH PCA SAH No SAH ... in other regions 3) Collateral circulation: in cases, the vertebral artery to the external carotid artery to anastomosis of the internal carotid artery; in one case, the subclavian artery to the...
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Tài liệu Báo cáo khoa học: Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant ppt
... distribution of the size of the inclusions was noticed Moreover, the percentage of cells presenting inclusions as well as the distribution of the size of the inclusions were dependent on when the analysis ... problem that the cell has to challenge to promote the formation and clearance of these bodies Aggregate clearance could therefore be balanced between the rate of huntingtin aggregation and the deleterious ... decreased the size of the inclusions but the effect was less intense (average size of 10 lm reduced to about 4–5 lm) In contrast, the size of the inclusions was not significantly altered by the presence...
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On public health use of influenza antivirals during influenza pandemics (with particular reference to the pandemic (H1N1) 2009) docx
... Education In the Initiation phase of a pandemic a decision needs to be made as to whether the severity of infection at the individual patient level is sufficient to offer antivirals to all of those ... development of new therapies Considerations should also be given to the public health implications of ensuring appropriate prescribing practices in order to limit the risk of the emergence and spread of ... hours after the start of symptoms Additionally, there is weaker evidence that suggests the drugs will reduce morbidity and even mortality if given within 48 hours after the start of symptoms in sicker...
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WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses docx
... and may point to the part of their body in which they feel the pain The ability to indicate the presence of pain verbally emerges between two and four years old Gradually they learn to distinguish ... assessed The information gathered from the history and physical examination will help to identify a differential diagnosis of the cause(s) of pain, and can guide for the choice of laboratory and ... display none of the expected cues They may deny their pain for fear of more painful treatment, for example, they may be fearful of injections Absence of these signs does not mean absence of pain and...
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