... total employment in a size class at the end ofthe year less total employment in the size class at the beginning ofthe year. The numbers presented in this sectionwere generated by the U.S. Census ... longitudinal data from individualfirms.4 The job figures presented in Chart 1 classify firms into size classes based ontheir size at the beginning ofthe period, which favors a finding of higher ... Finally, many ofthe largest firms operate in industries in which only a few firms operate or dominate the market.For the most part, these firms do not compete with one another on the basis of...
... Effects of active immunization of sheep against an aminoterminal peptide ofthe inhibin αC subunit on intrafollicularlevels of activin A, inhibin A and follistatin. Journal of Endocrinol-ogy ... Erk signalling pathways in mediating the effects of the gonadotropins and IGF on follicle cell function andon follicular development. The stimulation of inhibin-A, activin-A, follistatin, oestra-diol, ... assess the equal transfer ofthe proteins from the gel to the mem-brane. TBS-Tween was used to destain the membrane,which was then blocked in 5% Marvel in TBS-Tween for1–2 h. The blocking solution...
... throughout the world bears little resem-blance to teosinte, the original ancestor of corn. The newer techniques involv-ing genetic engineering, on the other hand, allow for the transfer of a fewgenes ... create signiịcant changes in the genetic makeup of plants and animals due to the random recombinationand sorting of thousands of genes. As a result of intervention by people, the hybrid seed corn ... commercially introduced in the U.S. in 1996 and have been rapidly adopted by farmers. It has been estimatedthat 24% ofthe corn and almost 70% ofthe soybeans and cotton grown in the U.S. in 2001...
... at the value determined from the amino acidsequence (45 320 Da).Measurement ofthe Kd of PLP bindingequilibriumPLP binding equilibria were analyzed taking advantage of the protein intrinsic ... toexplain the increase ofthe dissociation constant of the monomer–dimer equilibrium determined by the muta-tions. The results obtained inthe present study alsoshow that the monomeric form ofthe ... binding properties The affinity of wild-type and mutant forms for the cofactor was measured to evaluate the impact of the mutations on the structure ofthe PLP binding site.Because PLP binding...
... of GSK3 (using Li or SB-415286)appears to be sufficient for inducing activation of GS in muscle and fat cells, and that inhibition ofthe kinasepotentiates insulin action in muscle of insulin-resistant ... (1994) The inhibition of glycogensynthase kinase-3 by insulin or IGF-1 inthe rat skeletal muscle cellline L6 by wortmannin, but not rapamycin: evidence that wort-mannin blocks activation ofthe ... phosphatidylinositol3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement ofthe mammaliantarget of rapamycin (mTOR) pathway in the L-leucine-inducedup-regulation...
... group is given in Table 1. Following the tabulation of data, the results wereoffered to the participants upon request using the referencenumbers they were assigned at the time ofthe study.MaterialsMaterials ... minimal reference to the outline duringrecording. The first part ofthe lecture covered definitions of terms and a brief history of ceramics, which tended to be done in narrative form. Most of ... veryspecific interpretation ofthe meaning of lecture. Having examined over 20definitions ofthe word, we conclude that a lecture can be directed to oneperson, as in Mother lectured me for an hour on the...
... out of the savings banks movement, have done a Bringing the Hidden Giants to the Footlight: theRoleof Savings and Retail Banks in Increasing the Level of Access to Financial ServicesChris ... for disbursing of loans and collecting loan repayments. Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising in wholesale ... mainly individuals and small businesses, the traditional target client group of savings banks. By capturing and channelling more of the remittances into the financial system and intermediating...
... likelythat the increased rate of 13C label incorporation into the C6position of glycogen inthe ADM group is indicative of activated 6-phosphofructo-1-kinase, which can lead toincreased13C labeling ... labeling at the triose level. Such a mechanismcan lead to increases in labeling of glycogen C6 even in the presence of decreased activity ofthe indirect pathway,provided that the increase in glycolytic ... achieved inthe intactliver in vivo. The importance ofthe detection of labelincorporation into glycogen C6 while infusing [1-13C]glu-cose can be appreciated from the fact that this labelingpattern...
... derivatives thereof, while maintaining the hydrophobicity ofthe binding site.To test the effect ofthe mutations on the specificity forphenylacetylated substrates, the steady-state kinetic param-eters ... kcatrepresents the rate of acylation and Kmequals the binding constant of the substrate to the free enzyme. The results then indicateÓ FEBS 2002 Roleof active-site phenylalanines in penicillin acylase ... kinetic parameters ofthe enzymedetermine the yield ofthe product. The two most important parameters are (a) the rate of conversion ofthe substrate (acyl donor) vs. the rate of conversion of...
... Russell Investments // Roleof bank loans in a rising rate environment / p 7 Bank loans in rising interest rate environments In the past 20 years (since 1992), there have been three periods of significant ... surprise. The duration ofthe Credit Suisse Leveraged Loan Index is significantly lower than durations inthe traditional fixed income asset classes, reflecting the prevalence of floating rate instruments ... rising interest rates Russell Investments // Roleof bank loans in a rising rate environment / p 3 Exhibit 1 / Historic monthly returns (%) ofthe Credit Suisse Leveraged Loan Index (as of...
... apolar side chain of F331. Thus, the increment in the pKa of E399, in addition to it being closer to E187, mayhave resulted in a large shift inthe pKa of E187. Changes in the dielectric constant ... mMBicine buffer 7.0–8.5). The pH stability of Sfbgly50 was checked by incubation in the same buffers for a time equal to the assay time and thendetermining the activity remaining at the optimum ... [10,12].Nevertheless, it is not possible to assume that the same isoccurring inthe mutant R97M, because there is no data on the interactions between the substrate and the arginineresidue.Finally, another...
... after 3 min and thendeclined, while the formation of [3H]ATP was increasedlinearly with time within the first 15 min. After 30 min, the reaction reached equilibrium (Fig. 4A). Furtherexperiments ... (d)CMP.Discussion The aim ofthe present study was to define the role of Ureaplasma NMPKs inthe synthesis of nucleo-side triphosphates. Four Ureaplasma NMPKs werecloned, expressed and the recombinant enzymes ... cul-tured inthe presence of tritium-labelled deoxycytidineor thymidine, even though > 20% ofthe radioacti-vity was recovered inthe DNA fraction, indicating avery low dNTP pool in Ureaplasma...
... between the questionnaire and observation ratings of 0.49 for frequency of lifting, carrying, and transferring6–15 kg. Concerning the frequency of lifting, carrying,and transferring 6–15 kg, the ... 1.1–6.1Kneeling/squatting and lifting/carrying combinedcBoth no kneeling/squatting and no lifting/carrying 65 22.0 137 41.9 1.0 - 1.0 -Kneeling/squatting >0 – <870 hrs. or lifting/carrying >0 ... number of squatting and the duration of kneeling work. D'Souza et al. [20] examine the relation-ship between the daily amount of kneeling and knee oste-oarthritis inthe subset of participants...
... the greatest impacton the system because of the amount of salt and surfactants they transport, occurrather infrequently within the total number of samples examined. Finally, ... susceptible to the absorption and accu-mulation of NaCl. The levels of Cl- in the pine needles are related to the concentra-tion of salt in the solution, whether the solu-tion ... resistance to the action of aerosols is the result of the strength of the structures protecting the leaf, and increaseswith sclerophyllia and with the thickness of the cuticle.ACKNOWLEDGEMENTSThe...