... quantitatively) inthe dinucleosomesample is indistinguishable from that of high-molecularweight chromatin. Furthermore, inthe DNase I foot-print ofthe dinucleosome, the band resulting from acut on the ... nucleosomes inthe mainpeak, indicates that crosslinking is almost complete in the middle ofthe fibre, but some ofthe end-nucleo-somes are not crosslinked to the rest and thereforemust originate ... 2008 FEBS intervals. Robinson et al. [15] did not examine the sequentiallity ofthe nucleosomes, nor did they identify the path ofthe linker DNA or the location of the linker histones. They have...
... compared, for instance, to the making of an automobile or a calculating machine or a grain combine or a milling machine or to tens of thousands of other things. Delivery? Why, in this area where men ... McCullough Professor of Finance at the Katz Graduate School of Business ofthe University of Pittsburgh.S. J. Liebowitz is the Ashbel Smith Professor of Economics at the University of Texas at ... expensive—particularly the Middle West. This replacement began even before the general increase in the price of timber. But while the price of timber was not rising, the price of iron was falling during this...
... neither the state-carved niche of insolvency business, nor the formation of a professional body, but the steady increase in audit work that was to be the making ofthe modern UK accountancy profession. ... collapse ofthe Grays Building Society once again reminded small investors ofthe assumed role of auditing in safeguarding their deposits. The resulting investigation (Registry of Friendly Societies, ... 112) ThePowerof “Independence”: Defending and Extending the Jurisdiction of Accounting inthe UK By Prem Sikka Department of Accounting and Financial Management University of Essex,...
... [KR90]). The main idea ofthe coef-ficient is to find out the location of a document inthe space with respect to the cluster of the document and the next similar cluster. For a good clustering the ... extracting interesting information and knowledgefrom unstructured text. In this article, we discuss text mining as a young and in- terdisciplinary field inthe intersection ofthe related areas information ... con-taining this term. From the first ofthe remaining unmarked documents select again the term with the highest relative entropy as an index term. Then mark again this documentand all other documents...
... of tone in your colour, do the outlines in ink lines and then use another medium to produceareas of tone within the outlined shapes. I have used coloured pencilsinside the square outline of ... left, the firstschematic head is lit on the top, down one side of the face, one side ofthe nose, the upper edge of the upper lip, the lower lip and the top of the chin. The eyes are both in shadow, ... andcylinders placed vertically or lying on the ground) with all the vertical poles diminishing in size as they proceed along the limiting lines of perspective towards a central vanishing pointlying...
... generate these values, could be contained. The emotional intensity ofthe backlash against the intrusions of these subaltern groups suggests the importance of readingthese developments in ways ... . In such circumstances, theycertainly do honour to the liberality and taste of those who are at the expence of preserving them: but they are of little service in adorning and fertilizing the ... reproducing the Romantic myth of the originality ofthe creative act. The point of concluding withone ofthe most established Romantic poets is to dispel an either/or approach that simply inverts...
... capitalprofitability is declining. The internalization of information within the same institution may thusenhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing. The ... the 1930s, and especially inthe second post-world war period) replacesinvestment banking at the core ofthe financial circuit, not only by directly absorbing savings butby intervening inthe ... placing money withinvestment financial institutions inthe capital market, and hold the remaining share in non-interest bearing, short-term bank deposits (eq. 7). The share of savings going...
... feature of various cancers including cancer ofthe co-lon [33]. The amino acid analysis ofthe purified mucin gave high amounts of ‘mucin-like amino acids, serine, threonine and proline. Serine ... profiles (Fig. 3a and b) [26, 27] and whilst reduction was not quite complete, digestion resulted in most ofthe mucin eluting inthe included volume of the column, suggesting the findings of ... are shown in Table 2 with the signa-ture amino acids for mucins, namely, serine, threonine and proline comprising 48.3% ofthe total amino acids in the sample. The threonine levels in this particular...
... suggesting that differences inthe aglycon binding site play an important role inthe in- hibitory effect of this substance. In contrast, differ-ences inthe sugar binding site resulted in an ... agents for the treatment of dia-betes [7]. The mechanism of action ofthe anti-diabetic agents used for the treatment of type 2 diabetes, in- clude increasing insulin release, improving glucose ... saline (PBS; Invitrogen, Karlsruhe, Germany) and then incubated with 0.1 ml of a solution containing 5 àM CC2-DMPE and 0.02% pluronic acid in PBS. After in- cubation inthe dark for 30 min...
... alkylation within the DNA is the N7 position of guanine. Alkylation of guanine results in depurination by excision of guanine residues, causing DNA strand breakage through scission ofthe sugar-phosphate ... marrow and the gastrointestinal tissues from the cytotoxicity of CY in mice. We also profiled the changes ofthe expression of growth factors in gastric tissues in response to the damage by ... the protective effect of AP on CY-induced cytotoxicities in both the hemopoietic and gastrointestinal tissues was undefined. Any of these actions would extend the therapeutic application of...