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the human mind is not merely something in the story but is part of the story teller

the god of metaphysics jun 2006

the god of metaphysics jun 2006

Vật lý

... as the existing divine substance Thus the essence of a thing is not something in it, in the sense in which a mode of something is in it Rather, it is the thing itself Thus, since substance is in ... Green’s Idealism: Background VI Green’s Implicit Event Ontology VII The Human Mind is not Merely Something in the Story but is Part of the Story- Teller VIII The Case for Green’s Idealism in more Detail ... fox In this sense of essence, it would seem that it would be in the original lady, in the sense in which everything which is not in itself is in another thing This is not Spinoza’s use of ‘essence’...
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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Báo cáo khoa học

... segment of this domain is critical for high affinity agonist binding but not antagonist binding [14] The corresponding residue in the OTR is also an arginyl (Arg34) and furthermore this arginyl is ... arginyl at this locus is a constraining residue which contributes to maintaining the conformational switch of the V1aR in the off-state The unique ability of arginyl to fulfil this constraining ... interaction of the active receptor [28] In summary, Arg46 of the V1aR is required for high affinity agonist binding and signalling It is one of the constraining residues which maintain the V1aR in the inactive...
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Tài liệu [ Team LiB ] Configuring Your Safe Senders List The Safe Senders list is part of the Junk E-mail pdf

Tài liệu [ Team LiB ] Configuring Your Safe Senders List The Safe Senders list is part of the Junk E-mail pdf

Quản trị mạng

... Using the right-click menu is the easiest way to add new addresses to the list However, you'll need to use this dialog to remove or edit addresses from the list The list doesn't support ... can't enter addresses in the format of @*.microsoft.com You have to enter the entire text following the @ when you add addresses to the list After you've created a Safe Senders list, you can export ... Senders list, you can export it for use on other computers where Outlook 2003 is installed or use it as a backup copy if you need to reinstall Outlook or Windows [ Team LiB ] ...
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Báo cáo khoa học:

Báo cáo khoa học: "What does high NT-proBNP mean in septic shock patients? A part of the puzzle" pdf

Báo cáo khoa học

... natriuretic peptides during human sepsis as well as the confounding factors affecting their levels in ICU patients The great sensitivity of NT-proBNP in predicting prognosis could be largely counterbalanced ... respiratory failure in others Mokart and coworkers show that NT-proBNP could not discriminate these patients Future studies will have to precisely identify the determinants of the secretion of natriuretic ... result from this study is that NTproBNP continued to rise on day in patients developing cardiac dysfunction whereas it quickly decreased in the others This result suggests that mechanisms other than...
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Báo cáo y học:

Báo cáo y học: "MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection" pot

Báo cáo khoa học

... directed against MNF were performed All the rabbit sera obtained by immunization against part of or the whole MNF protein were specific to the MYXV infection but allowed the staining of cells infected ... bound by the N-terminal ANK domains and the outcome of these proteins could also greatly enhance our understanding of the multiple functions of the ANK/PRANC poxviral proteins during infection ... shown to inhibit the pro-inflammatory pathway, seemingly through an interaction with NF-B pathway To go further in the identification of the proteins interacting with MNF in a viral infectious context,...
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how can the human mind occur in the physical universe aug 2007

how can the human mind occur in the physical universe aug 2007

Vật lý

... from the minds of other species In the rest of the book, I try to use this architecture to develop key insights about the human mind Chapter 5, in particular, addresses the question of how the human ... states governing the encoding of the equation and the generation of the response The striking feature of the anterior cingulate is that there is almost no effect of learning, as shown in the bottom ... answer the question of how the human mind can occur in the physical universe This is because the human mind is not just the sum of core competences such as memory, or categorization, or reasoning...
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Báo cáo sinh học:

Báo cáo sinh học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient c" pptx

Hóa học - Dầu khí

... in the ER/Golgi of the infected cell A direct binding of E5 to the heavy chain of HLA-I seems under the light of our results improbable This is further supported by our findings using calnexin-deficient ... E5 expression results in diminished HLA-I surface staining in cells expressing calnexin, but not in calnexin deficient cells D) The upper part of the blot shown in A was incubated with anti-HC-10 ... Site-Directed Mutagenesis Kit of Stratagene) in order to disrupt the putative transmembrane helix of each of the three domains of the E5 protein [34-36] without altering the length of the protein All PCR-generated...
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Báo cáo hóa học:

Báo cáo hóa học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells" ppt

Hóa học - Dầu khí

... in the ER/Golgi of the infected cell A direct binding of E5 to the heavy chain of HLA-I seems under the light of our results improbable This is further supported by our findings using calnexin-deficient ... E5 expression results in diminished HLA-I surface staining in cells expressing calnexin, but not in calnexin deficient cells D) The upper part of the blot shown in A was incubated with anti-HC-10 ... Site-Directed Mutagenesis Kit of Stratagene) in order to disrupt the putative transmembrane helix of each of the three domains of the E5 protein [34-36] without altering the length of the protein All PCR-generated...
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Báo cáo khoa học:

Báo cáo khoa học: "Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21" pdf

Báo cáo khoa học

... showed the greatest increase in the Pre-G1 population (Figure 3B), further confirming the higher drug sensitivity of this cell line There is no dose-response toxicity by DCQ in normal intestinal ... and this increase was significantly inhibited by 10 μM DCQ (Figure 2B) This is in contrast to the observed increase in HIF-1a in response to μM or 10 μM DCQ under normoxia in this cell line In p53-/- ... leads to the phosphorylation of p53, thereby blocking its interactions with MDM2, and causing p53 stabilization This, in turn, stimulates the expression of the cyclindependent kinase (CDKs) inhibitor...
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Báo cáo y học:

Báo cáo y học: "Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 " ppt

Báo cáo khoa học

... seen in the analysis of infected T-cell bulk cultures (Fig 4D), closely matched the enhancement of gene expression in the subset of CD4 T-cells (Fig 4E) on the level of individual animals Of note, ... only 10% of that of human references [10], indicating that the transcriptional deficit also in this rodent had only partially been overcome by hCycT1 transgenesis Of note, this analysis required ... explored whether HIV-1R7/3 YU-2 Env GFP differs in its transcriptional phenotype in the rat -human species comparison from HIV-1NL4-3 GFP, the latter being the HIV-1 strain used in the experiments...
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Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc

Báo cáo khoa học

... to that of tyrosine in the L1 loop of RecA A chemical interference analysis revealed the protection of one of the two histidine residues, His97 and His163, of RecA by DNA binding [42] His163 could ... alanine If the aromatic side chain is involved in the interaction with DNA, then its replacement with alanine, a short side chain amino acid residue, should affect the DNA binding of the protein ... However, the fluorescence changes of these proteins were almost saturated at bases per monomer of poly(dT), showing that the changes were mainly due to the binding of the first DNA, while the binding of...
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THE REGULATORY STATUS OF BROADBAND SERV- ICES: INFORMATION SERVICES, COMMON CAR- RIAGE, OR SOMETHING IN BETWEEN? docx

THE REGULATORY STATUS OF BROADBAND SERV- ICES: INFORMATION SERVICES, COMMON CAR- RIAGE, OR SOMETHING IN BETWEEN? docx

Kĩ thuật Viễn thông

... end-to-end basis This is the FCC’s longstanding and consistent basis for determining the jurisdiction of traffic Treating the entire broadband medium as interstate in nature reflects that there is no ... instead is now rewarding cutbacks in investment This skepticism is based, in part, on the normal factors of the competition and the state of the economy But in the telecommunications industry, a significant ... players provide links or parts of links in the Internet’s Value Chain There are things that any one of these players might that could be harmful to the openness of the Internet but they aren’t regulated,...
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Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

Báo cáo khoa học

... the induction of lipid accumulation in the cells by the particles is enhanced when they are protected from oxidation, we investigated the mechanism of this effect by comparing the in uence of ... accumulation in macrophages, and that this is caused by a markedly increased rate of uptake of the particles and by a raised intracellular synthesis of triacylglycerol, but not of cholesteryl ester Furthermore, ... ACAT1, the isoform of the enzyme found in macrophages (Table 5), and this is consistent with our previous findings with CRLPs containing lycopene [35] In contrast to the lack of any effect of pCRLPs,...
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Báo cáo Y học: Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues doc

Báo cáo Y học: Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues doc

Báo cáo khoa học

... demonstrates that the C-terminal heparin-binding domain is located on the opposite side of a globular molecule to the interfacial binding surface [34], implying that this enzyme can interact simultaneously ... contained more than 50% of the native enzyme (Fig 1C) The distribution of the KE2 mutant between the two fractions was similar to that of the native enzyme (Fig 1C) In contrast, the activity of the ... 4B) The expression of other sPLA2s (IB, IIE and IIF) was undetectable The expression of other enzymes involved in the PGE2biosynthetic pathway in these colon carcinoma cell lines was also investigated...
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PULMONARY TUBERCULOSIS AMONG HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS IN THE ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IN DAR ES SALAAM MUNICIPAL, TANZANIA pdf

PULMONARY TUBERCULOSIS AMONG HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS IN THE ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IN DAR ES SALAAM MUNICIPAL, TANZANIA pdf

Sức khỏe giới tính

... the effect of HAART on the development of pulmonary TB among HIV infected patients Problem statement The prevalence of TB is increasing in many countries and is the leading infectious cause of ... resources, fishing and large and small scale industries The main business activities include insurance, travel, clearing and forwarding agencies, hoteliers, printing press to distributors of industrial ... adherence, past history of pulmonary TB; by administering a questionnaire to every participant Furthermore other clinical diagnostic information of co-morbidity including TB, clinical stage of HIV; treatment...
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Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx

Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx

Báo cáo khoa học

... ion-binding site is not conserved in hairpin If one assumes the same number of hairpins in V0 and F0, the rotor of V1V0ATPases has only half the number of ion-binding sites This is seen as the ... and an N-terminal sequence of this fragment was not obtained Therefore, it is not only not excluded that it was the c1 subunit but likely, as the c ring is rather stable, and the use of Triton X100 ... cells is competent in ATP synthesis, despite its unusual and unique membrane-embedded motor This is the starting point for a detailed analysis of the stucture and function of the rotor of the Na+...
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Báo cáo khoa học: Human-blind probes and primers for dengue virus identification Exhaustive analysis of subsequences present in the human and 83 dengue genome sequences doc

Báo cáo khoa học: Human-blind probes and primers for dengue virus identification Exhaustive analysis of subsequences present in the human and 83 dengue genome sequences doc

Báo cáo khoa học

... (i.e not contained in any of the other dengue genomes considered) 402 Fig Distribution of the percentage of human- blind 22-mers per genome that are unique (i.e not contained in any of the other ... sequences, the strains will be indistinguishable The likelihood of such an occurrence can be reduced by demanding more sequences for distinguishing between any two individual strains; this, however, ... less than six) of sequences, as used in the existing tests of dengue diagnosis, would not be able to reliably accommodate potential mispriming To minimize the probability of misdiagnosis, sequences...
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Andersen’s Fairy TalesBy Hans Christian Andersen.THE EMPEROR’S NEW CLOTHESMany years ago, there was an Emperor, who was so excessively fond of new clothes, that he spent all his money in dress. He did not trouble himself in the least about his sold pdf

Andersen’s Fairy TalesBy Hans Christian Andersen.THE EMPEROR’S NEW CLOTHESMany years ago, there was an Emperor, who was so excessively fond of new clothes, that he spent all his money in dress. He did not trouble himself in the least about his sold pdf

Khoa học xã hội

... forced, in spite of his opposition, to drink with the rest They took hold of the worthy man; who, hearing on every side that he was intoxicated, did not in the least doubt the truth of this certainly ... return invitation from the others One half of the company was already seated at the card-table, the other half awaited the result of the stereotype preliminary observation of the lady of the house: ... held his finger in the smoke of the kitchen-pot, immediately smelt all the dishes that were cooking on every hearth in the city—this, you see, was something quite different from the rose Now the...
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Báo cáo Y học: Puri®cation and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli doc

Báo cáo Y học: Puri®cation and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli doc

Báo cáo khoa học

... N-terminus of the mature maltose-binding protein Binding of the fusion protein to the IMAC gel in buffer containing 50 mM imidazole indicates the presence of the C-terminal histidine tag We conclude ... shortening of the C-terminus in combination with prevention of receptor glycosylation did not alter the ligand binding properties of the canine adenosine A2a receptor [27] This indicates that the ... binding-analyses on E coli and P pastoris membrane preparations, containing the S2 or the S4 somatostatin receptor fusion protein did not reveal speci®c binding of the agonist somatostatin In...
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Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf

Báo cáo khoa học: PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast pdf

Báo cáo khoa học

... together, these results suggest that the mutation did not induce any specific decrease in the de novo synthesis of a given phospholipid, including PI Hence, the rate of synthesis and the amount of ... de novo synthesis of this lipid (i.e the second hypothesis) According to this hypothesis, previously raised for mammals [34–36], the decrease in the percentage of stearic acid into PI in psi1D ... catalyzes the incorporation of this fatty acid in the sn-1 position of neo-synthesized PI Nevertheless, the results obtained in the present study are not in disagreement with those obtained by Kaliszewski...
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