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the dred scott decision is important because

Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx

Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx

Báo cáo khoa học

... 6].Identification of the region causing differentassociation characteristics The difference in association characteristics of the enzymefrom the two sources was surprising because the sequence is extremely ... Biochem. 269) Ó FEBS 2002This amino acid is located in the insert within the catalyticdomain, close to the catalytic His264, and the proximity to the active site may explain the effect of oligomerization ... argeinsertion between the catalytic Asp and His in TPP II. Thisregion would, of course, be difficult to model, but as Arg252 is so close to H is2 64, where the structure is conserved, the model is still expected...
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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Báo cáo khoa học

... [42,44]. The importance ofglycosylation is highly variable, therefore, and even incases where it is important, the effect may be eitherdirect or indirect. In this study, we set out to explore the ... 4A).Although these results attest to the importance ofN-glycosylation for the normal cellular localization ofHFE, we wondered whether this was a cumulativeeffect or whether there are specific ... sequenced.Throughout the text and figures, the protein expressed fromthis construct is frequently referred as the triple mutant.Mutated HFE cDNAs were subcloned into the BglII/SalI sites of the pEP7–GFP...
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Báo cáo khoa học: The N-terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+-dependent activity pot

Báo cáo khoa học: The N-terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+-dependent activity pot

Báo cáo khoa học

... conformation of the active site is not significantly changed on removalof the HBD. Because the HBD is important for sub-strate binding, the HBD may affect the interactionbetween the enzyme and ... alter the interaction between the sub-strate and metal ion, such that the scissile phosphategroup of the substrate and the Mg2+ion arearranged ideally. The effect of this alteration on the coordination ... Tma-RNase HI.Likewise, the stability of Tma-W22A was not analyzed because the stability of Tma-W22A is not significantlychanged even when the HBD is completely removed,and therefore it is highly likely...
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Metaphor, based on the association of similarity, is one of the two basic types of semantic transference that have been an interest for many linguistic researchers

Metaphor, based on the association of similarity, is one of the two basic types of semantic transference that have been an interest for many linguistic researchers

Thạc sĩ - Cao học

... which they are involved?+ The MODE OF DISCOURSE concerns what part the language is playing, what it is that the participants are expecting the language to do for them in that situation, the symbolic ... is thus a theory of the global distribution of the units of the grammar. The English grammatical rank scale recognized by Systemic Functional Grammar is as follows: In turn, each unit has their ... English Theme is the first element of a clause and providing what we call the departure for the starting point for the clause. By changing Theme we do not change the ideational meaning but the...
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In order to become competent in a foreign language, it is important for language learners not only to acquire new vocabularies and a new set of phonological and syntactic rules but also to learn what Wilson (1986)

In order to become competent in a foreign language, it is important for language learners not only to acquire new vocabularies and a new set of phonological and syntactic rules but also to learn what Wilson (1986)

Khoa học xã hội

... hóa Việt được con người mang theo từ buổi đầu mở đất vào phương nam, do trải qua các biến cố lịch sử xã hội nên đã có những thay đổi phù hợp với hoàn cảnh mới. Theo hướng đồng đại, ngoài yếu ... Điều này sẽ được trình bày cụ thể ở mục “Nguồn gốc” của chương hai và ba luận văn. Theo quy luật ngôn ngữ, theo xu thế phát triển của xã hội Việt Nam hiện nay, việc người dân di chuyển từ nơi ... triển riêng, gắn với đặc điểm xã hội và tâm lí con người địa phương. Về nguyên tắc làm việc, theo chúng tôi, muốn xác định đó có phải từ địa phương Nam Bộ hay không, người ta phải căn cứ vào...
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The BMATT course - What is it

The BMATT course - What is it

Anh ngữ phổ thông

... engaging the lug of the scabbard with the slot in the bayonet, ensuring that the sharp edge of the bayonet faces away from the hook end of the scabbard. The wedge shape on the back of the blade ... muzzle of the rifle. The blade end of the handle is a release catch which secures it onto the muzzle of the rifle. The blade end of the handle can be used as a bottle opener. THE SCABBARD is normally ... British Army Infantry Weapons: Worksheet One 1. The following are the names of parts of the three main weapons used by the British Infantry. Can you put the names on the pictures below in the...
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Tài liệu [ Team LiB ] Configuring Your Safe Senders List The Safe Senders list is part of the Junk E-mail pdf

Tài liệu [ Team LiB ] Configuring Your Safe Senders List The Safe Senders list is part of the Junk E-mail pdf

Quản trị mạng

... Safe Senders List The Safe Senders list is part of the Junk E-mail filters. If you choose to allow external content from addresses listed in your Safe Senders list, you need to check the configuration ... select Add Sender to Safe Senders List or Add the Domain @[domain-name] to Safe Senders List. The sender's fully qualified domain name is listed in the menu selection, as shown previously ... you need to check the configuration of the list. You can add addresses and domains to the Safe Senders list directly from an email message. Click on the InfoBar or right-click in any image...
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Tài liệu Báo cáo khoa học: A DExD⁄ H box RNA helicase is important for K+ deprivation responses and tolerance in Arabidopsis thaliana docx

Tài liệu Báo cáo khoa học: A DExD⁄ H box RNA helicase is important for K+ deprivation responses and tolerance in Arabidopsis thaliana docx

Báo cáo khoa học

... quantitativereal-time PCR analysis indicated that AtHELPS is mainly expressed in the vascular tissues, such as the midrib of the cotyledon, the hypocotyl, and the rootvasculature (Fig. 2E), and is upregulated ... III, IV, V, and VI. The arrow marks the highly conserved residues Asp-Glu-Val-His in motif II. The detailed schemeof the conserved motifs in AtHELPS is shown on the underside. The amino acids in ... analysis of the T-DNA insertion for the helps mutant and OE lines of AtHELPS. (A) The conservedmotifs of DExD ⁄ H-box RNA helicases in AtHELPS. Numbers represent the amino acid position of the AtHELPS...
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Tài liệu Báo cáo khoa học: Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process docx

Tài liệu Báo cáo khoa học: Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process docx

Báo cáo khoa học

... line on the right), where the 19 aminoacid insertion of Rac1b is found, is disordered in the crystal. The mostly disordered structures of the switch II region are compati-ble with important ... addition. Therefore, the reason why Lys147rather than Lys5 is the main acceptor site for ubiquitinin Rac1 remains to be elucidated. Of note, however, is that recent studies on the role of the Rab-like ... supplied by the authors. Any queries (otherthan missing material) should be directed to the corre-sponding author for the article.Ubiquitination of Rac1 is regulated by JNK O. Visvikis et al.396...
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Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc

Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc

Báo cáo khoa học

... mostother vertebrate AChEs is missing in C. intestinalisAChE, Tyr70, a member of the peripheral site, which is replaced by Ile97. The Kssof C. intestinalis AChEfor ATCh is rather high and this ... intestinalisAChE is the longest in the tree; this long branchlength is typical of many C. intestinalis genes and is aresult of rapid evolution in the species [34,37]. Thisrapid evolution and the ... AChETexon,as only one of the seven aromatic residues is preserved.It is highly unlikely that this protein is an active AChE because it is missing a member of the catalytic triadand the main aromatic...
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Tài liệu The future of cinema is smooth, crisp and amazing docx

Tài liệu The future of cinema is smooth, crisp and amazing docx

Sân khấu điện ảnh

... events, theater, and dance. Christie is leading the industry in developing HFR technology, and is in the process of rolling out a transition plan for exhibitors. The drive is on to make theater ... the color information must be discarded to allow the video data to move across this interface. Some observers suggest the visual impact is minimal, but it’s nonetheless a quality compromise. ... director James Cameron is working with Christie in leading the global R&D effort to make the industry ready for this big shift – from the film set and all the way to the local movieplex. HFR...
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The Relativity Theory Revisited: Is Publishing Interest Rate Forecasts Really so Valuable? pptx

The Relativity Theory Revisited: Is Publishing Interest Rate Forecasts Really so Valuable? pptx

Ngân hàng - Tín dụng

... 180859095100105110average central bank lossSTRpWarsaw, November 2008 The Relativity Theory Revisited: Is Publishing Interest Rate Forecasts Really so Valuable?0LFKDï%U]R]D%U]H]LQDAdam ... Ř5HVXOWVRIVLPXODWLRQVDUHGHSLFWHGLQ)LJXUHVDQG$VWKHVDPSOHOHQJWKhbeaused by agents rises the central bank loss tends to be lower. This is in line with the intuition WKDWXVLQJODUJHUGDWDVHWVE\DJHQWVHQDEOHVWKHPWREHWWHUDSSUR[LPDWHWKHWUXHODZRIPRWLRQRIWKHHFRQRP\DQGWKXVORZHUFHQWUDOEDQNORVV$VUHJDUGVWKHIUDFWLRQeWKHPRUHDJHQWVKDYHWRUHVRUWWRWKHPDFURHFRQRPLFSURMHFWLRQVSXEOLVKHGE\WKHFHQWUDOEDQNWKHKLJKHUWKHYDOXHVRIFHQWUDOEDQNORVVDQGWKHKLJKHUWKHJDLQIURPGLVFORVLQJWKHLQWHUHVWUDWHSDWK2QWKHRWKHUKDQGLWLVZRUWKQRWLQJWKDWVKRZLQJWKH,6DQG3&FXUYHVWRDOODJHQWVe ... argminUHDFKHGIRUK(.$JHQWVFDQFKRRVHGLIIHUHQWVDPSOHOHQJWKVRISDVWGDWDIRUWKHSXUSRVHRIOHDUQLQJ,Q the baseline scenario it is assumed that the learning sample smplVWUHWFKHVRYHUSHULRGV\HDUVZKLFKFRUUHVSRQGV to the perpetual learning gain K...
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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Báo cáo khoa học

... decreasing agonist affinity and (b) promoting the agonist-induced active conformation due to the loss of astabilizing constraint on the ground state of the receptor.Therefore, the agonist had a lower ... than the wildtypeV1aR but once the agonist bound, the receptor was morelikely to signal. This dual role suggests that binding of the agonist releases the Arg46-mediated constraint on the ground ... which the N-terminus of the OTR is replaced with the corresponding sequence of the V1aR [10]. The role of the N-terminus has beenaddressed recently by alanine-scanning mutagenesis of the N-terminus...
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Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt

Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt

Báo cáo khoa học

... where the G-less cassette is controlled by the adenovirus major late (AdML) promoter(lane 1). We found that the activity of the natural R2promoter is 64% of the AdML promoter strength in thisbasal, ... the R2 TATA-box is important for initiation both in vitro (Fig. 3A) and in vivo(Fig. 3B) when the R2 5¢-UTR is either deleted or mutated.In contrast, the in vivo results suggest that when the ... oligonucleotideincluding the transcription start and the downstream sequence from of the mouse R2 gene. The protein-DNA complex is indicated by the arrow to the right of the autoradiograph. Lanes...
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