... is the cut-off value in the Recommendations of the American Heart Association [35] andthe trigger for initi-ation of insulin treatment for ICU patients recommendedby the American College of ... that are the root of hospitalacquired hyperglycaemia and in the long term lead to development of diabetes.Although the incidence of hospital acquired hypergly-caemia differed between the three ... role and sepsiswhere systemic inflammation is an important contribut-ing factor. The difference in the incidence of hyperglycae-mia is probably a consequence of those differences and the differences...
... gene is the product of a gene duplication ofthe autosomal dmrt1agene and was designated dmrt1bY [8] or Dmy [9]. Itwas shown to be the only functional gene in the wholeY-specific region ofthe ... embryo-genesis, all the evidence suggests that sex determinationmight disobey the conventional rules of evolutionaryconservation. The common picture emerging here is that the genes at the top ofthe cascade ... result, the common emerg-ing picture is that the genes at the top ofthe cascade are not conserved,whereas the downstream genes have homologues in a much broader spec-trum of species. Among these...
... story ofthe fragmentation of the ideal of literature as a public sphere. The excesses gener-ated by the French Revolution, on the one hand, and by the infor-mation revolution, on the other, ... from the super-stitions ofthe weak, andthe imposing craft ofthe subtle’ (323).Thomas Holcroft placed a similar emphasis on the art of printing’in the defence of this progressivist vision of ... rank, of everyage, andof both sexes. They are intimately acquainted withevery language, the dead as well as the living. To the culti-vation of letters they join that ofthe arts; andthe mechanicsare...
... volume, (c) there is substantial scientic literature addressing the reproductive and/ or developmental toxicities of these chemi-cals, and (d) they are of concern to the public. These seven ... retained in the carcass at the end of 72 hours, and were 56, 46, and 17% for the low, medium, and high doses, respectively. The remainder ofthe radiolabeled activity was excreted in the feces ... (NIEHS) ofthe National Institutes of Health and Dr. Michael Shelby is the director.1 The CERHR broadly solicits nominations of chemicals for evaluation from the public and private sectors. The...
... (Met1)-ONC(M23L) by the addition of AAP, as described in the Materials and methods. Completion ofthe hydrolysis wasconfirmed by the disappearance ofthe (Met1)-ONC(M23L) signal in the MALDI-TOF mass spectra ... analyzed by MALDI-TOF MS. The addition ofthe protease is considered the zero time point. The relative intensities ofthe peaks from the mass spectrawere used to calculate the fraction of Pyr-ONC (M23L), ... simplify the protocol and shorten the time needed to obtain a fully active ONC compared withother procedures described in the literature. The application of MALDI-TOF MS to the characterization of...
... Na+ and Cl–[1]. The main physiological function ofthe transporter isbelieved to be the control ofthe concentration and dwell time of GABA in the synaptic cleft. Because the transport of one ... Solid linesrepresent the exponential fit with half-lives of 22 and 23 h forwild type GAT1 in the absence and presence of dMM, respectively, and of 12 and 5.5 h for the DDN and DDQ mutants, respectively.Fig. ... in the regulation of the stability and trafficking of GAT1. It has beenreported that a variety of molecular chaperones and folding enzymes assist the folding of newly synthesizedproteins in the...
... volume of 0.2MMes/NaOH buffer (pH 5.0). The dead time of the apparatus was 3 ms, andthe noise level was indicatedin the first place as the absorbance fluctuations for the residual solution ofthe ... loss ofthe axial water ligand. The correspondingspectral changes in the Soret band were therefore followedby stopped-flow and rapid-scan techniques, and the observed first-order rate constants of ... the autoxidation of T. akamusi hemoglobin VII below pH 6.0,as well as for the b-chain in the autoxidation ofthe humanHbO2tetramer [11]. The other role ofthe distal histidine isin the maximum...
... Hence, the dependence of k2 of wild-type and all mutants on the concentration of MgCl2was investigated at 278, 283, 288, 293 and 298 K.Table 1. Kinetic and thermodynamic parameters ofthe reaction ... at the time of chloroplast origin had poorly definedinteractions between Cyt f and plastocyanin and/ or plasto-cyanin and photosystem I, and subsequently the nature of the interactions in the ... Hencefor both organisms, the changes in DSà of the electronicfactor would have the same sign as the measured trend.Further discussion ofthe effects of ionic strength onthermodynamic parameters...
... the t rees, and furthermore it will lead to the mutation of conserved motifsotherwise common to the sequence family to which the gene belonged at the time of endosymbiosis. The dissolution of ... of all ofthe enzymes of the pathway (Fig. 4), it is clear that only about half of the enzymes ofthe tricarboxylic acid cycle, the major pathway of carbon metabolism in mitochondria of oxygen-respiringeukaryotes, ... and that some ofthe subunits of PDH, OGDH and OADH are related. The functional and evolutionaryrelationships between the subunits of these enzymes aresomewhat complicated. In a nutshell, the...
... to understand the effects of bisphenol A on the development oftheprostate gland and urinary tract. Studies should attempt to confirm these findings and include longer periods of follow-up ... from bisphenol A exposure to thedevelopmentofprostate can-cer in these animals. Future research to clarify the role of bisphenol A in thedevelopmentof prostate cancer presents a scientific ... exposures. Prostate Gland and Urinary Tract There is some evidence that perinatal exposure to bisphenol A in rodents may alter prostate gland and urinary tract developmentand predispose the prostate...
... The large and small of banking: the case ofthe ICICI bank and microfinance 23 Box 6: The role ofdevelopment finance institutions in an inclusive financial development strategy: the case of ... improves the screening of fund-seekers andthe monitoring ofthe recipients of funds, which improves the allocation of resources. Secondly, in the presence of information and transactions costs, the ... mismatches. The mix of such maturity and currency mismatches can enhance the fragility ofthe financial system during periods of exchange rate depreciations and rising interest rates. The lack of development...
... Number of Non-Replacement Faculty HiresReport ofthe AAA/AAPLG Ad Hoc Committee to Assess the Supply and Demand for Accounting Ph.D.s 13 the characteristics ofthe faculty members demanded andthe ... 1384 100.0%Report ofthe AAA/AAPLG Ad Hoc Committee to Assess the Supply and Demand for Accounting Ph.D.s 9Percentage ofthe Specialty Percentage ofthe Specialty Percentage ofthe SpecialtyTABLE ... respondents The bottom row is the percentage ofthe responses represented by each subpopulation.Report ofthe AAA/AAPLG Ad Hoc Committee to Assess the Supply and Demand for Accounting Ph.D.s 10Supply of...
... with the identification theorythan with the competition theory.III THE "COMPETITION" THEORY OF FUNcTIONALriY AND ITs TESTSA. The "Competition" Theory The "competition" ... lens of the competition theory, are nonfunctional. Applying each of the above six tests to the three examples confirms the affinity of thesetests for the competition theory.Under ... Accordingly, these six tests alignthemselves more readily with the competition theory than with the identification theory.IV THE Two TEoRIEs OF FUNCTIONALrIY AND THE AESTHETICFUNGT1ONALrIY...
... on the tennis courts next to their condo. Most ofthe guests knew and liked Susie. Always the star ofthe Pool Party,she sang old-fashioned standards by the light of tiki torches in front ofthe ... aname. He lined them up on the flat edge at the back ofthe tub. Then he clicked the stopwatch just as heswept the marbles into the water. They raced down the porcelain slope, clicking and rattling, ... brothers,” hesaid, and I was a paperboy andthe son of a grocery man. So the high school fraternities didn’t look my way, and I was just one ofthe boys from what approximated outside of the...
... both the coordinated and the liberal models. The first will be exemplified by the Nordic countries, in particular Finland and to some extent Sweden; the second by the US andthe UK, andthe ... historical variants ofthe Keynesian welfare state. The paper compares three cases of governance ofthe biotechnology sector: Finland and Sweden, the USA andthe UK, and Australia. The aim is to integrate ... transfer, entrepreneurship, and so on. In none ofthe countries included in this study is the role of pursuing these objectives the sole responsibility of either the state or the market. Instead,...