... desired by their wives.I’m not sure exactly why, but women everywhere were shocked. Andbythe flood of letters from around the country—from both women and their grateful husbands—Shaunti and I ... survey -design expert Chuck Cowan, former chief of census design for the U.S. Census Bureau, andthe well-respected survey company Decision Analyst. They came together to help us design and conduct ... can come when the opposite sex finally has their eyes opened to things they simply didn’t understand about us guys before.In this book, the shock is on the other foot. Now it’s their turn to...
... incentives the hard glare of a passer -by and the offender’s feelings of guilt—are at least as powerful as finan-cial and legal incentives. If social forces get us most ofthe way there, how ... with the family ofthe little girl to whom they donated Andrew’s liver. (They also donated his heart, but that baby died.) And, not surprisingly for a scholar who pursues real-life subjects, the ... that the outcome of that election came down to a handful of voters; but their names were Kennedy, O’Connor, Rehnquist, Scalia and Thomas. And it was only the votes they cast while wearing their...
... and conditions of license. Color Atla s of Pharmac ology3rd edition, revisedand expanded Heinz Lüllmann,M.D.Former Professor and ChairmanDepartment of PharmacologyUniversity of KielGermanyKlaus ... owing to the formation ofthe epithelial brush border(submicroscopic foldings ofthe plasmalem-ma). The absorbability of a drug is character-ized by the absorption quotient,thatis ,the amount ... mechanism of action and therebyexpands therapeutic possibilities. Examples of such fundamental innovations from re-cent years include the ACE inhibitors(p.128), the lipid-lowering agents of the...
... DPP-IV). Another potential bond can beproposed between the OH atom of Tyr380 andthe car-bonyl group ofthe ligand. Finally, the valine sidechain ofthe ligand, pointing towards the active ... into the active site ofthe crystalline structure of PepX from L. lactis ;and4 , docked into the active site ofthe modeled structure of PepXfrom S. gordonii.P. Rigolet et al. Sites for thedesign ... 2). The interactions ofthe bound ligand with the resi-dues ofthe specificity site (Fig. 4A) reveal good stack-ing between the pyrrolidine ring ofthe drug and the side chain of Tyr380 (Pos1 subsite),...
... consumption of FNRsq by the second process, the same amount of FNRsqis produced bythe first one. This isconsistent with the high Kdvalues proposed for the interaction of FNR and Adx and with the ... the changes introduced in the redox cofactor environment upon complex formation. Theyare therefore related to the specificity andthe strength of the protein–protein interaction. Therefore, the ... interaction,allowing the determination of a Kdvalue of 25 ± 3 lMfor the [FNRox:Adxox] complex andof 17 ± 2 lMfor the [FNRox:Adx(4–108)ox] complex (Table 1).Study ofthe kinetics of reduction of...
... to a person (The Wizard) at another terminal who answered the subject's requests by consulting paper copies ofthe database tables. The experimenter then gave the details ofthe two tasks. ... these words, either by gener- ating co-operative error messages to enable the user to rephrase the query and so avoid the use ofthe problematic word [Adg88, Ste88] or by user training. The ... cluding their age, theme, medium, and location. The subjects had to find a set of paintings which together satisfied a series of requirements, and they did this by typing English sentences into the...
... costs of normal pressure rectification. Dependingon the difference between the temperatures at the bottom tW and at the top tD of the column, and on the price ofthe heating steam CH, the optimum ... experimental data on the hydraulicbehaviour of packed columns for the development of a new method for the standardpresentation ofthe fluid dynamics of columns with any type of packing design. The basicprinciples ... pressuredrop above the loading line as well as separation efficiency at the minimum ofthe curvent/H = f(uV). The advantages ofthe method developed by Beck lie mainly in the sim-ple use ofthe correlations,...
... food stocks, andthe mood ofthe garrison. The tactics of the Daily Mail captured the attention ofthe nation; the newspaperdramatized the situation ofthe town by emphasizing the danger that ... they do know the public’’ (quoted in Koss Rise and Fall ). The Victorian cult of personality had moved into the press bythe turn of the century, andthe military version ofthe focus on individuals ... notions of Boer inhumanity towardAfricans, the pro-war argument ofthe ‘‘negrophilists.’’ The other cat-egory into which mentions of Africans fall is praise ofthe loyalty of the Cape Boys and the...
... (92.34(78.8)69.8)796avgqpsf++∆==Therefore, the average pressure increase in the clay layer is, The pressure poat the center ofthe clay layer is,po= γsandh sand+ γ’sandh’sand+ γ’clayh’clay= ... 0.00018y. Values are solved by plugging in the x and y values, which these values are found by using the x-y coordinate system off the mat foundation. Determine the average soil reaction. ... steel lying in the East-West direction ofthe mat shown below with external dimensions of 42 feet by 74 feet. The columns are all 15 by 15”, the LF = 1.6, fc’ = 3 ksify= 50 ksi, and qall=...
... men and 0.1–0.6% inwomen [2]. The prevalence rises to 4.4% of men and 1.8% of women over the age of 65 [4]. A two-fold increase inincidence of gout has been reported in the USA and NewZealand ... publication was obtained from the patient. The authors wish to thank Dr. William Hsu and Dr. Tania Pringle for their contribution to the interpretation ofthe radiographs and providing key information ... backpain.Two days later the swelling had increased in the dorsalaspect of his right wrist and hand. Wrist flexion was lim-ited by 80% with severe pain. Pain was present on palpa-tion ofthe scaphoid...