the action of drugs on single neurones in the brain
PROGRESS I N BRAIN RESEARCH VOLUME 36 BIOCHEMICAL AND PHARMACOLOGICAL MECHANISMS UNDERLYING BEHAVIOUR doc
... Samuels (Birmingham, U.K.) Behavioural actions of some substituted amphetamines D A Buxton (Salisbury, U.K.) The action of drugs on single neurones in the brain P B ... us to apply zonal centrifugation to the separation of the P fraction , G B ANSELL AND SHEILA SPANNER The zonal centrifugation of the P , fraction The technique of zonal centrifugation was developed ... a ZONAL CENTRIFUGATION OF BRAIN SUBCELLULAR FRACTIONS I I 100 200 300 400 rnl I 500 I 600 Fig The subfractionation of the PZfraction from rabbit cortex on a discontinuous sucrose gradient in...
- 217
- 262
- 0
Báo cáo khoa học: Action of palytoxin on apical H+/K+-ATPase in rat colon pdf
... 6–9 Ionic selectivity of the palytoxin-induced pore Assuming that palytoxin might induce cation-permeable pores in the apical membrane, the Isc evoked by the toxin should consist of an in ux of ... this enzyme is involved in the formation of the palytoxininduced channels The enzymatic activity [19], the amount of mRNA, and the protein expression of the H+/K+-ATPase are higher in the distal ... borate in the mucosal solution using a palytoxin concentration of 10)8 molÆL)1 For theoretical reasons it is not possible that administration of palytoxin to the basolateral side of an epithelium...
- 7
- 351
- 0
Báo cáo sinh học: " Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer" potx
... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding of the present study was that the function of MDA-7 in prostate cancer ... obvious impact on the action of MDA-7 Together, this may suggest that TGase-4 interferes with the action of MDA-7 at a stage before receptor activation From the immunofluorescent staining of TGase-4 ... stained for MDA-7, mostly in the cytosolic region and perinucleus areas Over-expression of TGase-4 in the cells appeared to reduce the cytosolic staining of MDA-7 (Figure 5A) Figure Inhibition of...
- 9
- 374
- 0
báo cáo hóa học:" Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer" potx
... limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells The most intriguing finding of the present study was that the function of MDA-7 in prostate cancer ... obvious impact on the action of MDA-7 Together, this may suggest that TGase-4 interferes with the action of MDA-7 at a stage before receptor activation From the immunofluorescent staining of TGase-4 ... stained for MDA-7, mostly in the cytosolic region and perinucleus areas Over-expression of TGase-4 in the cells appeared to reduce the cytosolic staining of MDA-7 (Figure 5A) Figure Inhibition of...
- 9
- 448
- 0
Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx
... level of the C3 convertase In contrast, CD59 inhibits the terminal pathway of complement activation, preventing the incorporation of C9 into the MAC [18] While DAF expression is increased in the rheumatoid ... expression in normoxia is independent of NO [21], suggesting that a distinct additional mechanism is activated by the combination of statins and the hypoxic microenvironment, resulting in induction of ... normoxic conditions (Figure 7a) The use of C5-deficient serum prevented the generation of the C5b-9 MAC, therefore facilitating investigation of the effects of DAF Treatment of HUVEC Available online...
- 12
- 510
- 0
Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... self-destruction during oxidation Taurine-containing cells are present in the myenteric plexus and submucosal plexus of the enteric nervous system in the stomach Taurinergic neurons in the muscle layer of ... the control (C) group (n = 5) low taurine concentrations ≤ 10 -7 M Therefore, the neuronal pathway involved in acid secretion induced by low taurine concentrations may predominantly involve in ... Ca 2+ -influx from the extracellular space could cause the inhibition of taurineinduced acid secretion In addition, taurine effectively increases cAMP concentration in stomach by binding to GABAA...
- 10
- 490
- 1
The effect of leadership on employee commitment in FPT distribution company a full range leadership approach
... employees to stay in the organization considering the costs of leaving In continuance commitment, the employees consider the disadvantages of leaving the organization and avoid quitting Continuance commitment ... explaining the purpose of the study to the prospective respondent General 33 instructions on completing the questionnaire and the importance of completing all questions were included The covering ... gaining new sights into the phenomenon; undertaking preliminary investigation before a more structured study of the phenomenon is done; describing central concepts and constructs of a phenomenon;...
- 119
- 816
- 0
Báo cáo y học: "Comparative study of control selection in a national population -based case-control study: Estimating risk of smoking on cancer deaths in Chinese men"
... 780–796, 7.9%) The selection of controls in this study was based on three assumptions: (1) the individuals in both control groups had, in 1980, smoking habits that were similar to those of the study ... population-based case-control studies were formed within the study base with one group of cases and two different control groups The information on smoking history was obtained by interviews We interviewed ... in Shanghai was conducted where the surviving spouse was the informant and both husband and wife had reported their smoking habits in the early 1980s.17 Information obtained from the spouse on...
- 9
- 532
- 1
Tài liệu Effect of KNO3 Spraying on yield and yield Component of rice on degraded Soie in Bac GiangSummer rice – 2009 docx
... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of umfiiied ... umfiiied grain 1000 grain weight(g) Grain yield Tab 5: Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2 ... DO5 Number of grain/pan % of umfiiied grain 1000 grain weight(g) Grain yield Tab 6: Effect of KNO3 Spraying on rice yield on degraded Soie in Bac Giang 2009 ( Quinal/ha) Treat Spring Rice Summer...
- 9
- 433
- 0
Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... responses We found inconsistencies in 12.2% of the sample, indicating the difficulties in communicating the information about the mechanism of action To assess the influence of inconsistent responses, ... Demographic information was asked at the conclusion of the questionnaire The Spanish and the English version of the questionnaire are available from the authors upon request The questionnaire was ... personal beliefs within the time constraints of the family planning clinics On the other hand, a client is potentially done a disservice if the information provided conceals or downplays information...
- 10
- 824
- 0
Effects of initial form of chromium on electrokinetic remediation in clays
... Based on the actual mass of the soil used in electrokinetic cell and the concentrations measured in the contaminated soil prior to electrokinetic testing b NDsnot detected in both soils Initially, ... migration, approximately 11.5% of the initial total chromium in the soil, occurred in the anode reservoir in glacial till containing chromium in Cr(VI) form alone A slight amount of chromium in the ... exists in the dissolved phase near the anode because of low pH conditions andyor the formation of anionic complexes, which migrated into the anode Fig 8a,b show the concentration profiles of Cd(II)...
- 13
- 404
- 0
Effects of innital form of chromium on electrokinetic remediation in clays
... Based on the actual mass of the soil used in electrokinetic cell and the concentrations measured in the contaminated soil prior to electrokinetic testing b NDsnot detected in both soils Initially, ... migration, approximately 11.5% of the initial total chromium in the soil, occurred in the anode reservoir in glacial till containing chromium in Cr(VI) form alone A slight amount of chromium in the ... exists in the dissolved phase near the anode because of low pH conditions andyor the formation of anionic complexes, which migrated into the anode Fig 8a,b show the concentration profiles of Cd(II)...
- 13
- 613
- 0
Effects of innitial form of cr on electrokinetic remediation in clays
... Based on the actual mass of the soil used in electrokinetic cell and the concentrations measured in the contaminated soil prior to electrokinetic testing b NDsnot detected in both soils Initially, ... migration, approximately 11.5% of the initial total chromium in the soil, occurred in the anode reservoir in glacial till containing chromium in Cr(VI) form alone A slight amount of chromium in the ... exists in the dissolved phase near the anode because of low pH conditions andyor the formation of anionic complexes, which migrated into the anode Fig 8a,b show the concentration profiles of Cd(II)...
- 13
- 254
- 0
báo cáo hóa học: " Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" doc
... utilized in the ISOLDE trial [14,28] However, definitions of an acute exacerbation in the literature vary [2,19,28-30], indicating that there is no clear consensus on the definition of an exacerbation ... effect of the exacerbations on the health status deterioration in the Fatigue and Mastery of the CRQ and the Symptoms of the SGRQ These results support our hypothesis that subjects experiencing ... study interval, then more subjects may have experienced exacerbations Second, concerning the definition of an exacerbation, we selected the definition of an acute exacerbation of COPD similar...
- 8
- 594
- 0
báo cáo hóa học:" Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" pdf
... utilized in the ISOLDE trial [14,28] However, definitions of an acute exacerbation in the literature vary [2,19,28-30], indicating that there is no clear consensus on the definition of an exacerbation ... effect of the exacerbations on the health status deterioration in the Fatigue and Mastery of the CRQ and the Symptoms of the SGRQ These results support our hypothesis that subjects experiencing ... study interval, then more subjects may have experienced exacerbations Second, concerning the definition of an exacerbation, we selected the definition of an acute exacerbation of COPD similar...
- 8
- 421
- 0
Báo cáo khoa học: "Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats" ppsx
... heads) in seminiferous tubules H & E stain, ×50 and multiple layering of the tubular endothelium, degeneration of germ cells, and the formation of many multinucleated giant cells in atrophied seminiferous ... homogenized for in 5.0 ml of physiological saline solution [17] The homogenate was filtered through a nylon mesh and then 0.1 ml of filterate was diluted with 2.0 ml of saline solution containing 4% trypan ... abnormalities of sperms One of the histopathological lesions observed in the present study was the formation of many multinucleated giant cells in atrophied seminiferous tubules The giant cells...
- 7
- 394
- 0
Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps
... an insight into a new and interesting mechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis Competing interests The author(s) declare that they have no competing interests ... capacity On the other hand, the inhibitory activity of the mAb on CD69 membrane expression on neutrophils indicates that these cells are among the possible targets of anti-TNF-α activity in RA, ... chemiluminescence production production Neutrophils were obtained as described in the legend to Fig and then tested for chemiluminescence (CL) production in resting conditions (spontaneous CL) or in...
- 6
- 579
- 0
Báo cáo y học: "Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production" ppt
... and of the possible mechanism and regulation of the effect of CD147 on MMP production, will help in the development of innovative therapeutic interventions for RA 10 11 12 Competing interests The ... CyPA-mediated cell migration into joints, all of which may contribute to the cartilage and bone destruction of RA These findings, together with a better understanding of the relationship between CD147, ... image of the double immunofluorescent assay The expression of CD68+ (green) and CD147+ (red) cells, and the co-expression of CD68+CD147+ cells (yellow) in the lining and sublining layers of rheumatoid...
- 11
- 459
- 0
Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... result in clinically significant improvement of pulmonary function Since none of the patients included in these studies were selected on the basis of progression of ILD or the time from the SSc-related ... assessing the weighted mean difference in the meta-analysis The overall pooled analysis included the mean changes of the FVC and the DLCO after 12 months of therapy obtained from the observational ... control treatments Using a test of interaction, we performed a subgroup analysis of the change in FVC and DLCO values from baseline to 12 months in studies using oral administration of CYC versus those...
- 9
- 477
- 0
A potential protective effect of α-tocopherol on vascular complication in spinal cord reperfusion injury in rats pptx
... recovery of hind limb function The placing/stepping reflex (SPR) was assessed by dragging the dorsum of the hind paw along the edge of a surface This normally evokes a coordinating lifting and placing ... reduces the formation of edema in these cells This may be due to the anti-inflammatory effect of α-TOL by inhibiting PGE2 production [43] The inhibitory effect of α-TOL on PGE2 production in the ... of long-term administration of αTOL in spinal cord reperfusion injury against high oxidative stress induced by ischemia; and to investigate the role of α-TOL in the inhibition of COX-2 activity,...
- 9
- 240
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25