technologies competition and the new role of regulation introduction and synopsis of the book
Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc
... signal on and off Caspase activation is under the direct control of kinases and phosphatases, and the indirect control of phosphorylation through the regulation of other apoptotic proteins Furthermore, ... They induce the permeabilization of the mitochondrial membrane with the release of cytochrome c and the formation of the apoptosome [38] The major pro-apoptotic protein Bax exists mainly in the ... Inhibition of PP1 by OA enhances the phosphorylation of p53 at Ser15 and Ser37, decreases the expression of bcl-2 and increases the expression of bax in human laryngeal epithelial cells and human...
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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... establish the importance of GSK3 in the acute regulation of glucose transport in terms of its regulatory control of GS in muscle and fat cells we have investigated the effects of Li and the anilinomaleimide, ... elements implicated in the regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their effects and that of insulin on p70S6K, PKB, ... hormonal regulation of GS, our data does not support a role for GSK3 in the acute regulation of glucose transport based on (a) the differential effects of Li and SB-415286 on hexose uptake and (b) the...
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Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
... play a major role in determining both the level of expression and the location of the start of transcription of PS1 In the Ets family of transcription Ó FEBS 2004 Regulation of the presenilin ... using the concentration of protein in the extract as an internal standard The activity of ()119/+178) PS1CAT in the presence of the empty vector was taken as 100% The values represented in the ... We have studied the transcriptional regulation of PS1 in control, except in the experiments testing the activity of Ets different cell types and in particular the role of Ets and Sp1 10 related...
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Báo cáo khoa học: 2-Oxo acid dehydrogenase complexes in redox regulation Role of the lipoate residues and thioredoxin pot
... entirely to the catalytic role of these domains Rather, the advantage appears to depend on the ability of the lipoyl group to protrude from the inner core of the complex, indicative of the biological ... function of (a) concentrations of the reaction substrates and products, (b) kinetic properties of the component enzymes, E1, E2 and E3, and (c) their stoichiometry and interactions within the complex ... confirmed the inhibition of the overall reaction by the low molecular mass disulfides [41] The data pointed to the exchange of redox equivalents between the complexes and the medium, involving the dihydrolipoate...
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Explaining Bank Failures in the United States: The Role of Self-Fulfilling Prophecies, Systemic Risk, Banking Regulation, and Contagion pdf
... decrease at the beginning of the 1990s Table of the appendix provides further details about the distribution of the bankruptcies across US states ranked in the order of the total number of bank failures ... bank failures Based on the coefficients of the baseline model of column of table 1, the solid line of figure represents the predicted number of bank failures whilst the bars show the corresponding actual ... constructed with the amount of deposits reported to the World Bank Since 1973, the Federal Reserve System has reported the amount of reservable deposits and the total amount of (mandatory and excessive)...
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AN INCREASING ROLE FOR COMPETITION IN THE REGULATION OF BANKS doc
... 1/12 of 1% of the assessable deposits and was the same for all insured institutions regardless of the riskiness of their assets or the size of their equity capital or the capability of their management ... and enforced in the interest of the regulated industry, rather than in the interest of the economy at large General laws, on the other hand, tend to be more immune and therefore more robust and ... because of significant differences in the structure of competition, the preferences of purchasers of bank products (and the set of alternatives they face) and the institutional context The following...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
... mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, on the other hand, significantly ... proliferation and mineralization [2,26-29] These two stages are the result of a specific sequential regulation of gene expression from the early phase of osteoblast proliferation to the final steps of mineralization ... matrix and promote healing [24] In this study, we have documented the relative efficiency of bone growth factors FGF-2, TGFb, and PGE2 markedly enhanced the synthesis of the total protein content of...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
... mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, on the other hand, significantly ... proliferation and mineralization [2,26-29] These two stages are the result of a specific sequential regulation of gene expression from the early phase of osteoblast proliferation to the final steps of mineralization ... matrix and promote healing [24] In this study, we have documented the relative efficiency of bone growth factors FGF-2, TGFb, and PGE2 markedly enhanced the synthesis of the total protein content of...
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Báo cáo y học: " The role of IFN-γ in regulation of IFN-γ-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures" potx
... cells and produced IFN-γ [23] The present study focuses on the regulation of the IP-10 secretion The aim was to investigate the pathways of IP10 secretion in a in vitro system including the cell ... contact, little is known of the regulation of the Th1 IFN-γ/ IL-12 pathway upon intercellular interaction between lung epithelial cells and leucocytes Since increased activity of the IFN-γ/IL-12 pathway ... response to IFN-γ, thereby attracting more lymphocytes to lung tissue and support the use of the A549 and CALU-3 cell lines as a model of the primary cell system As example, application of cigarette...
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THE ROLE OF THE CTD PHOSPHATASE RTR1 AND POST-TRANSLATIONAL MODIFICATIONS IN REGULATION OF RNA POLYMERASE II
... process the lengthening mRNA at the 5’ end As the RNAPII moves along the transcribed region of the gene, the shift of the CTD phosphorylated at serine to serine (S2-P) occurs through the activity of ... S5-P) In this thesis we will study the RNAPII modifications on both the CTD and the globular core of the enzyme in the presence and absence of Rtr1 IV Mechanisms for RNAPII degradation and recycling ... Overview of current known role of Rtr1 and other CTD Phosphatases Figure shows our current working model of the role of RNAPII CTD phosphorylation with an emphasis on phosphatase activity The specific...
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ELUCIDATING THE ROLE OF REDOX EFFECTS AND THE KU80 C-TERMINAL REGION IN THE REGULATION OF THE HUMAN DNA REPAIR PROTEIN KU
... ELUCIDATING THE ROLE OF REDOX EFFECTS AND THE KU80 CTERMINAL REGION IN THE REGULATION OF THE HUMAN DNA REPAIR PROTEIN KU DNA double strand breaks (DSB) are among the most lethal forms of DNA damage and ... interest in redox regulation that has the potential to influence the DNA binding activity of Ku (51) To further understand the role of the C-terminus of Ku80, we created two mutants The first mutant ... (14) These studies revealed the ring shape exists in the presence and absence of DNA as well as a great deal of structural homology between the Ku70 and 80 subunits, despite the fact that they...
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Elucidation of the physiologic role of TRIP br2 in cell cycle regulation and cancer pathogenesis
... function in the regulation of cell cycle progression during late G1 and the G1/S transition 57 Figure Proposed model for the function of TRIP-Br3/HEPP/CDCA4 in the regulation of E2F1 and p53 ... the cell cycle is arrested as a result of p21 inhibition of CDKs, thus preventing the replication of damaged DNA (Figure 3) (Ko and Prives, 1996) Mdm2, on the other hand, plays an important role ... spectrum of human cancers such as squamous cell carcinomas of the head and neck, the esophagus, the tongue and larynx, carcinomas of the uterine cervix, astrocytomas, non-small-cell lung cancers, soft...
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The role of NF kb and histone deacetylase in gene regulation
... THE ROLE OF NF-κB AND HISTONE DEACETYLASE IN GENE REGULATION JOANNE CHRISTABELLE CHEW SOO FEN (BSc (Hons.), THE UNIVERSITY OF MELBOURNE) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... Sathyavageeswaran, and Dr Esther Wong for all the cell lines and reagents, and constructive suggestions that they have given me for the completion of the NF-κB and WIP1 project, and also not forgetting ... into the intermembrane space of the Chapter Introduction cytoplasm The eventual consequences of both pathways are similar as they both converge on the activation of key effectors of apoptosis-the...
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The role of TRIP br proteins in the regulation of mammalian gene transcription and cell cycle progression
... cycle regulation The summation of the above observations and findings has led to the synthesis of a hypothetical model to explain the dual role of hTRIP-Br1 in the regulation of mammalian cell ... growth (in the cases of Rsc1 and Rsc2) 15 (1.2.2) The role of PHD zinc fingers and bromodomains in the regulation of eukaryotic gene transcription To date, the molecular function(s) of the PHD zinc ... Given that the E2F transcription factors promote the G1-to-S transition and that E2F-1 plays a role in the regulation of cell proliferation, the unique ability of the TRIP-Br proteins and the PHD-bromodomain...
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Circuit theory of finance and the role of incentives in financial sector reform
... creating and advancing liquidity to producers; along the circuit, the financial system governs the supply and demand of funds and, at the end of the process, it determines the condition for the closure ... conceptualization and recent evidence CTF clarifies the role of the financial system in the functioning of a monetary market economy of production At the start of the circuit process, the financial ... institutions and strengthen the complementarity between the formal and the informal sectors The poorest people of rural and urban societies live beyond the frontier of formal finance, or outside the formal...
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Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc
... kinds: + The change of consumer-demand modal, market and the attitude to the availability and diversity of goods + The pressure of reducing cost + The development of Information technology + The pressure ... world The Association has the role of coordinating the activities of the members in order to protect the interests of the members and improve the position of Vietnam in the international freight ... formalities need to be renewed to facilitate export and import The General Department of Customs, the Ministry of Trade and examining bodies, and the Bureau of Standards and Measures should have...
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Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
... where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised ... women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 ... with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of...
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The role of language in adult education and poverty reduction in Botswan
... improve the quality of life of the poor and rural people adult education programs should include as one of its components the observation and imitation of the artisans and other skilled persons in the ... maintains the hegemony and the gap between the poor and the rich, the major and minority groups In order to redress poverty the adult education program needs to be aware of the social functions of language ... for the betterment of their conditions It could mobilize the so called minorities to oppose their status and challenge the hegemony of the majority communities in Botswana 31 In most parts of the...
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153 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards
... transaction to the acquire and is reimbursed the amount of the sales ticket by the acquirer (4) - The acquirer then summits the ticket to the issuer for payment, via the ICO interchange and settlement ... maintaining the flow of funds and information between issuing and acquiring members The exchange of financial information is called clearing The exchange of the actual funds for the transaction and the ... separate tasks and roles in their own working field: 14 - Head of Department: be directly responsible for the work and plans of department to the Director, make plans and assign tasks to the staff...
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