... effect modification by each of candidate SNP via adding an interaction term ofthe SNP and the pollutant simultaneously with both the main effect terms adjusting for the same covariates as the above ... the significance of interaction termsof individual SNP and pollutant The current version of MTP allows one to identify the significance of a group of candidate variables to reduce the false discovery ... determine the level ofthe test in advance This study reported adjusted p-values Then, we quantitatively estimated associations between the pollutants and 8-OHdG across those carrying variants of the...
... body The stalwart Englishman of to-day can neither get into the armour nor be placed in the sarcophagus of those sons of men who were accounted the heroes ofthe infantile life ofthe human world ... build ofthe man and woman increases As in the highest developments ofthe fine arts the sculptor and painter place before us the finest imaginative types of strength, grace, and beauty, so the ... our modern city The most radical changes in the houses of our city are in the chimneys, the roofs, the kitchens, and their adjoining offices The chimneys, arranged after the manner proposed by...
... Staff, and the honor, honesty and fair dealing ofthe Agency We court the fullest and freest investigation, either by patients themselves or any friends of theirs in this city, either of whom we shall ... imbecile, before they will be convinced? Such proof is at hand Not an asylum in any country but has its score of such; not an asylum record-book but chronicles the sad histories of thousands of ... exhaustive Aware ofthe number of worthless and oftentimes actually injurious remedies that are being advertised and recommended for the cure of these affections, and the bogus doctors and worthless...
... consequence ofthe strange happening ofthe serpent landing from the ship the end ofthe island on which the Temple of Æsculapius stood was shaped into the form ofthe bow of a ship, and the serpent of ... Chrysippos Anatomy Empiricism Serapion of Alexandria CHAPTER V Roman Medicine at the end ofthe Republic and the Beginning ofthe Empire Asclepiades of Prusa Themison of Laodicea Methodism Wounds of ... Forum, and trace its course to the Tiber In the Forum, too, to the left ofthe Temple of Castor, is the sacred district of Juturna, the nymph ofthe healing springs which well up at the base of the...
... reproductive organs at puberty The female generative organs The function ofthe reproductive organs The age of puberty in the female The function ofthe ovary The function ofthe womb—Why menstruation ... compared to the effects which the venereal diseases have had upon mankind It is useless to think that these diseases can be driven out ofthe land Any hope of this nature is the impression ofthe dreamer ... after the cord falls off—A pouting navel —Bathing baby—Clothing the baby— Baby's night clothes—Care ofthe eyes —Care ofthe mouth and first teeth— Care ofthe skin—Care ofthe genital organs—Amusing...
... out ofthe reach ofthe flames will Sometimes a stick or oar thrust into the bank or in a crevice ofthe wall behind the fire is more convenient than a tripod Again, you can without any hanging ... though I had been a traveller interested in the sale of them The drinking of hot tea out of these mugs is quite a beautiful art You hold the wire handle between finger and thumb and put the little ... proteid, and then the fact that some ofthe essential tissues ofthe body (the muscles, the heart and the blood) are being dangerously impoverished is very likely to be overlooked In the case...
... combination therapies for other types of cancer Combination therapy of SAHA and retinoic acid has been examined for resistant acute promyelocytic leukemia in which SAHA enhanced the anti-cancer effect of ... Mock and a2KD cells were treated with TSA and IL-13 same as in panel B mouse models of human cancer IL-13Ra2-negative pancreatic cancer cell lines (Panc-1 and ASPC-1) were implanted in the flanks ... being assessed as a cancer therapy in a variety of preclinical and clinical trials [4,17,18] The significance of IL-13Ra2 expression in cancer is not known and the mechanism of its upregulation...
... combination therapies for other types of cancer Combination therapy of SAHA and retinoic acid has been examined for resistant acute promyelocytic leukemia in which SAHA enhanced the anti-cancer effect of ... Mock and a2KD cells were treated with TSA and IL-13 same as in panel B mouse models of human cancer IL-13Ra2-negative pancreatic cancer cell lines (Panc-1 and ASPC-1) were implanted in the flanks ... being assessed as a cancer therapy in a variety of preclinical and clinical trials [4,17,18] The significance of IL-13Ra2 expression in cancer is not known and the mechanism of its upregulation...
... development ofthe study question to the revision ofthe final manuscript Each ofthe four authors has made a significant contribution at each phase ofthe study AQLQ12+ Standardised version ofthe Asthma ... function and environmental stimuli) are the means ofthe responses to the questions in each ofthe domains Symptom and Medication Diary Each morning and evening patients scored how much they were bothered ... similar in the two age groups (Table 4) and correlations between each domain ofthe AQLQ12+ and other measures of asthma clinical status were also very consistent in the two age groups (Tables and 6)...
... semblances of dependency in later relationships, semblances of others' betrayal and of their own powerlessness The hypothesized shared mechanism of disorder for complex PTSD and BPD has not been ... mislearn from their private experiments faster than they make progress in therapy with analysis ofthe transference and of scenarios of old betrayals The crisis intervention ofthe Cape Cod Model ... which the person cannot ascertain one way or the other The sufferer can neither become certain enough ofthe other's trustworthiness to recommit to the current relationship, nor can he become...
... Effects of soybean isoflavones on cell growth and apoptosis ofthe human prostatic cancer cell line LNCaP Jpn J Clin Oncol 1998, 28:360-363 Shen JC, Klein RD, Wei Q, Guan Y, Contois JH, Wang TT, Chang ... to the medium to incubate for another 24 h Radiation was given with a linear accelerator (Varian, Palo Alto, USA) with MeV and a dose rate of 2.4 Gy/min 24 h later the medium was changed and the ... outlined the study, helped HAW to perform the majority ofthe experimental work and drafted the manuscript MRF supervised the radiobiological experiments and molecularbiological work PT carried out the...
... Figure quantitative RT-PCR (QPCR) genes of transgenes on the expression of hostanalysis ofthe effects Real-time Real-time quantitative RT-PCR (QPCR) analysis ofthe effects of transgenes on the expression ... number of internodes was measured from the base ofthe plant to the base ofthe inflorescence when all ofthe flowers were developed Page of 14 (page number not for citation purposes) BMC Plant ... mature XAS plants suggests that these plants may be producing more GA than the control, non-transformed plants Transcript levels of genes involved in GA biosynthesis and leaf expansion The dwarfing...
... is quantitatively the most important scavenger of oxidants (4-6), and is thus an important antioxidant within the body(7) The formation of carbonyl groups on amino acid residues as a result of ... marker of protein degradation and turnover (8, 9) In fact the oxidative modificationof proteins and lipids has been implicated in the etiology of a number of diseases including atherogenesis and ... smoking cessation it further supports the role of antioxidant disturbances in the progression of COPD The data however can not indicate the time scale required for the resolution of smoking related...
... 16 XZ and MV performed the experiments XZ analyzed the data and drafted the manuscript ATD and BB designed the experiments and revised the manuscript 17 Acknowledgements 18 We thank Stephan Heynen ... with the G19F and E37L mutations, and assayed their activity in HeLa X1/6 cells The activity of these 20 rtTA variants varies considerably (Fig 3A) Like the escape variant S, the A, C and H variants ... considerably (Fig 3A) The phenotype of these variants can hardly be predicted by the chemical nature ofthe residue This is probably due to the location of this residue in the helix connecting the DNAbinding...
... project, and to Dr Jurvansuu Jaana for the critical review ofthe manuscript This thesis is dedicated to my father Yang Zhoumou and my mother Peng Liying, whose love, encouragement and support ... precisely the extent of modifications Furthermore, these biological modifications are inflexible because they can only be performed during the process of vector construction; once the vector ... significantly greater success in termsof cell transfection, and is therefore the standard form of PEI for gene delivery Highly branched polymers such as the 25 kDa and the 800 kDa molecular weight...
... example of such form of complementarity is offered in India by the non-banking financial companies sector (Pahwa, 1998) Another important advantage ofany informal-formal link is that formal financial ... institutions and strengthen the complementarity between the formal and the informal sectors The poorest people of rural and urban societies live beyond the frontier of formal finance, or outside the formal ... the circuit, thefinancial system governs the supply and demand of funds and, at the end ofthe process, it determines the condition for the closure ofthe circuit As discussed, the conditions...
... sensitivity and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective ofthe test itself, lessening the impact ofany unique features ofthe ... characteristics ofthe study populations of biologic and non-biologic DMARD users and the performance characteristics ofthe effectiveness algorithm between biologic and DMARD treatment episodes, the data ... 10, 6%), and more than joint injection (n = 11, 6%) The results ofthe sensitivity analysis that excluded biologic treatment episodes for patients with anyofthe several comorbidities of interest...
... criteria of good tests and theoretical ideas on test reliability and validity as well as achievement tests Chapter 3- The study is the main part ofthe thesis showing the context ofthe study and the ... error If the r = 0.60, it means that only 60% ofthe test score is reliable and the other 40% may be caused by an error Thus, the higher the reliability coefficient is, the lower the standard error ... kind of software in a server Before the examinations, the person who is in charge of preparing the tests will use the software to mix the test items in the item bank and print out the tests All the...
... statistics ofthe angle of arrival, but would yield no information regarding the correlation between time and angle of arrival In order to get an accurate picture ofthe time and angle of arrival and ... compare the performance ofthe available algorithms, information is needed to characterize the time delays and angles of arrival ofthe major multipath components in the indoor channel The angle of ... would be to look at a narrow range of angles using an antenna with a narrow angular resolution, measure the time domain impulse response ofthe channel, rotate the antenna, and repeat this until the...