... cross-clamping of the aorta should be considered as an adjunct to other initial haemorrhage control measures such as the evacuation of blood, direct surgical bleeding control, or packing ofbleeding ... administration of FFP, controlof bleeding, and an eventual improvement in the outcome ofbleeding patients is lacking, most experts would agree that FFP treatment is beneficial in patients with massive bleeding ... patients in need of urgent surgical bleeding control, and patients presenting with haemorrhagic shock and an identified source ofbleeding should undergo immediate surgical bleedingcontrol unless...
... determinants of the probability of default (PD) of bank loans We focus the discussion on the role of a limited set of variables (collateral, type of lender and bank-borrower relationship) while controlling ... banks almost doubled the market share (in terms of number of loans to corporations) at the expense of that of commercial banks The lack of knowledge of the business segment and the desire to increase ... analysis of the role of collateral In this subsection the model is estimated allowing for differences in the effects of type of lender and number of banks relationships in the probability of default...
... sex, primary tumor, date of initial diagnosis of primary cancer, date of radiographic diagnosis of BMs, number and location of BMs, neurologic symptoms, presence/absence of extracranial disease, ... date of progression of BMs, type of second treatment for BMs, death of the patient Data were recorded in a central data base system at the Regina Elena National Cancer Institute For the aims of ... clinical practice, the treatment of BMs is often planned on the basis of the resources available at each treating center The incidence of BMs reported in our series of patients for each tumor was...
... effects of different HES solutions in this area In vitro studies are limited because of the absence of the endothelium and compensatory mechanisms like buffering and the controlof pH and the lack of ... evidence of effects of various especially fast degradable HES preparations in patients undergoing surgery with major blood loss or in critically ill patients, especially those with sepsis It seems of ... Analg 2002, 95:858-865, table of contents Franz A, Bräunlich P, Gamsjäger T, Felfernig M, Gustorff B, Kozek-Langenecker SA: The effects of hydroxyethyl starches of varying molecular weights on...
... transfusion of unit of packed RBCs During the study period, no bedside procedures were performed, doses of vasopressor and sedative agents were kept constant, and the patient’s position in bed (head of ... regression line of the first 14 seconds of increased StO2 (seven StO2 values) following the ischemic period This StO upslope of the reperfusion phase was used to quantify the intensity of the reactive ... using a cutoff diameter for small vessels < 20 microns After stabilization of the images using the AVA 3.0 software, we defined the perfused (small) vessel density (PVD) and the proportion of perfused...
... reductase activity as a consequence of the coincident expression of hexose-6-phosphate dehydrogenase (H6PDH), which facilitates enhanced, localized concentration of the cofactor for 11β-HSD1, namely ... Willebrand factor staining) Page of 10 (page number not for citation purposes) Figure Autocrine activation of cortisol and the regulation of fibroblast function of fibroblast function Bone marrow, ... regulation of fibroblast function Page of 10 (page number not for citation purposes) Arthritis Research & Therapy Vol No Hardy et al Figure Expression of 11β-HSD1 in synovial tissue Co-localization of...
... requirements of 6.3 of IEC 60079-0 not apply 6.4 Circulating currents The provisions of 6.4 of IEC 60079-0 apply, except for nL, [nL] or [EX nL] apparatus 6.5 Gasket retention The provisions of 6.5 of ... and the applicable parts of IEC 60079-0 for the method(s) of protection used 6.2 Mechanical strength of apparatus Mechanical strength of apparatus shall comply with 6.2 of IEC 60079-0, except for ... constructed to minimize the risk of occurrence of arcs or sparks capable of creating an ignition hazard during conditions of normal operation NOTE For the purposes of this standard normal operation...
... [19] During immobilization, a flow rate of 10 lLÆmin)1 of HBS was maintained The surface of the chip was activated by injecting a mixture of equal volumes of 0.2 M N-ethyl-N¢-(3-dimethylaminopropyl)carbodiimide ... Interaction involving dimerization of decorin and binding of both collagens to the inner surface of decorin (B) Interaction of type I collagen with the inner surface of the decorin core protein and ... Surprisingly, the stability of the ternary complex was higher than that of the dimeric complex of decorin with type I or type VI collagen The existence of an interaction of decorin with type I and...
... different conformational forms of HbA is a key factor in the complete description of the sigmoidal behavior of HbA oxygenation Taking advantage of the photosensitivity of the heme Fe–ligand bond ... based on determination of the bimolecular association rate constant of O2 rebinding and the quantum yield of BR, c The latter value is defined as the ratio of the number of O2, which succeed in ... number of the absorbed light quanta It should be pointed out that the ratio of the number of the dissociated O2 molecules to that of the absorbed light quanta defines the primary quantum yield of...
... different types of Dutch text: Wikipedia, Twitter data, transcriptions of conversational speech, and web pages of Frequently Asked Questions (FAQ) The Wikipedia corpus that we use is part of the Lassy ... type experiments in terms of percentages of saved keystrokes Prefix means: ‘use the previous characters of the current word as features’ Buffer 15 means ‘use a buffer of the previous 15 characters ... Histogram of text prediction scores for the Neuro−QA questions trained on Medical Wikipedia 20 40 60 80 percentage of keystrokes saved 20 40 60 80 percentage of keystrokes saved Figure 4: Histogram of...
... length a value of around 14 nm—corresponding to a pb value of around 1.4× 1023 m−3, see Eq 16—and for the size of the grain-grain contact a value of around 100 nm (one fifth of the value of the grain ... increase of the resistance of the accumulation layer As already demonstrated in [13], the sensor resistance will be the result of the combination between the contributions of the resistances of the ... latter case, the value of the Debye length is around 0.8 nm—corresponding to a pb value of around 4× 1025 m−3—and the value of the size of the grain-grain contact a value of around nm (a bit more...
... terminal products of the biosynthesis of both forms of lipid A are not required for survival of the cell Another interesting case can be found in the knockout of fabZ, the protein product of which catalyzes ... Indeed, the mole number of ATP needed for one mole of lipid A in the core EFMs varies between 36 and 42 In contrast, the amount of NAD(P)H is 54 per mole of lipid A in all of these EFMs In this ... per mole of product of interest produced is given in Table Key enzymes of lipid biosynthesis and contribution to metabolic capacity Next, we analyzed in detail the effects of the knockout of several...
... to assess the statistical significance of the differences between the normalized intensity volumes of individual spots of the control (Agxt+ ⁄ +) and those of the hyperoxaluric (Agxt) ⁄ )) group ... findings Further studies of the sources of endogenous oxalate synthesis in humans are needed The phenotypic features of Agxt) ⁄ ) mice are probably the direct consequence of impaired glyoxylate ... report in this article a proteomic analysis of the changes in expression levels of various enzymes of liver and kidney metabolism linked to the lack of AGT Results We first attempted to detect...
... of approximately h at 100 °C To determine the optimal pH for the esterase, the activity of EstD was measured in a pH range of 5– EstD displayed > 70% of its maximal activity in the pH range of ... In the absence of a 3D structure of EstD, it was decided to build a 3D-model of EstD Since there are no close structural homologs of EstD, modeling was based on threading A model of EstD was made ... activity but, because of the availability of an ever increasing number of complete genome sequences, bioinformatics has become an important tool in the discovery and identification of novel industrial...
... 60 mL of buffer B luminol), and solution B (10 mL of dimethylsulfoxide containing 11 mg of p-hydroxycoumaric acid)] Blot membranes were incubated in a mixture of mL of solution A, 400 lL of solution ... the isolation of membrane vesicles, 20–25 g of cells (wet mass) was suspended in 200 mL of 50 mm Tris ⁄ HCI, 10 mm MgCI2, and 420 mm sucrose (pH 7.5) (buffer A) After addition of g of lysozyme ... analysis of the stucture and function of the rotor of the Na+ F1F0-ATP synthase from A woodii, the first containing V0- and F0-like c subunits Experimental procedures Growth of cells and isolation of...
... acquisition of an interdomain intron in the evolution of c-crystallins, and of both interdomain and intermotif introns in the evolution of b-type crystallin genes (Fig 3) The likelihood of late-in-evolution ... whose crystallin genes have a full complement of introns This finding is in support of late gains of introns, rather than introns loss in the evolution of crystallin-type genes An alternative model ... the results of a statistical analysis [42] of pairs of gene paralogs may only be interpreted to favour intron gains rather than intron losses in these genes Recent data [43] in support of the theory...
... and hypertrophy (i.e an expansion of adipocyte volume as a result of the accumulation of lipids) Consequently, knowledge of the origin and molecular controlof adipocyte progenitor commitment ... involve Controlof adipose tissue development the binding to a large (> 3000) overlapping set of target genes [17,18] The formation of brown adipocytes requires the expression of an additional set of ... important for our understanding of what controls the expansion of fat mass in different individuals Moreover, it is also important to understand the origins of each of the different white and brown...
... loss of adipose tissue triggers a high degree of insulin resistance and signs of other metabolic dysregulation similar to visceral WAT expansion The importance of maintaining at least remnants of ... The microvasculature of adipose tissue is necessary for the expansion of adipose mass not only as a result of its ability to prevent hypoxia, but also as a potential source of the adipocyte progenitors ... decrease the quality of the lymphatic capillary of these roles are certainly interconnected, here we focus on the role of lymphatics in lipid absorption, the consequences of lymphatic dysfunction...
... to the definition of temperature as a measure of the mean kinetic energy of the gas molecules; to a definition of pressure as a result of the impulse of molecules on the walls of the body containing ... awareness of the importance of verification and validation of CFD codes and the development of related methodologies This has given rise to the definition and evaluation of families of test cases ... stability, and control aircraft 38 18 11 11 Figure I.1.6a Evolution of the CFD tools over the last 40 years at Boeing, with an indication of the influence of CFD on the reduction of the number of wing...