organisations together with the independent and serious study of the candidate the main contributions of the thesis to the knowledge have been made which are as follows
Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx
... quantification of the local background and evaluation of the array homogeneity, which is taken into account in the normalization Furthermore, in order to consider the purity and quality of the mRNA, ... was applied using a factor calculated from the intensity ratios of internal standards in the test and reference samples The presence of the internal standard probes at different locations of the ... up with a list of 33 mRNAs that are significantly downregulated by at least one of the five siRNAs in at least one of the three cell types (supplementary Table S16) We found that about 40% of these...
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Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf
... Fig The 1652 and 1270 cm)1 bands can be assigned to a-helix in the human PKIb; the 1666 and 1247 cm)1 bands are the characteristic frequencies of the random coil structure Meanwhile, the 1682 and ... 1636 and 1625 cm)1 can be assigned to extended chain structures; the bands at 1683, 1669 and 1663 cm)1 are possibly assigned to turns or bends; and the band at 1647 cm)1 is likely to be the random ... buffer The pooled fraction was stored at )20 °C for further study The concentration of the proteins was determined by the method of Lowry et al [14] and the purity was examined by SDS/PAGE [15] Assay...
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Đề tài " On the periods of motives with complex multiplication and a conjecture of GrossDeligne " pdf
... primitive and odd Dirichlet character Another way to prove this equality is to apply (9) to the definition of the function η 3.2 The proofs The notations of Sections and 2, and the conventions of subsection ... influenced by the algebraic subvarieties of X; a subvariety of X has a cycle class in the dual of a rational homology space of X and the duals of these cycle classes span a subspace of homology, which ... element of the dual of the Q-vector space H The number H H Per(ωu ) is independent of the choices of v and ωu , up to multiplication by a nonzero algebraic number, and only depends on u and H In the...
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Đề tài " Existence and minimizing properties of retrograde orbits to the three-body problem with various choices of masses " potx
... Proof of Main Theorems We begin with the proof of Theorem 1: Proof of Theorem Assume m3 = 1, M = m1 + m2 + Let F (m1 , m2 ), G(m1 , m2 ) be as in (5), (6) Suppose F (m1 , m2 ) > G(m1 , m2 ) Then ... + m2 + m3 is the total mass The homotopy class of the ˜ ˜ projection αφ of αφ in V \ Δ over t ∈ [0, 1] is one of the two generators for ˜ \ Δ) The left side of Figure depicts the path α over t ... because they are not covered by classical approaches, but also due to the amusing symmetries they exhibit On the other hand, these orbits were constructed under the assumption that some masses are...
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Báo cáo khoa học: Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure doc
... or the regulation of protein or the cytoskeleton Only a few are specific to xenobiotic detoxification One, the glutamine synthetase gene was previously shown to be associated with the response of ... gigas exposed to hydrocarbons [22] and parasites [47] The binding of lipopolysaccharide and b-1,3-glucan binding protein to form LGBP has been shown to activate the prophenoloxidase cascade The ... pollutants compared with other species [72–75] The results given here provide a preliminary basis for further study of detoxification processes and other physiological responses to herbicides in the marine...
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báo cáo hóa học:" The short form endometriosis health profile (EHP-5): translation and validation study of the Iranian version" ppt
... patients to complete and declare their understanding of the items to ensure face validity Page of The sample size calculation was based on an assumption that at least 10% of women in the reproductive ... experiential, and conceptual equivalence was reached and a final version of the questionnaire (the Persian EHP-5) was provided The final translated version of the questionnaire was given to 10 patients to ... rather than literal translation Translators with one of the authors compared their translations and produced a single provisional version Then two other professional translators translated the...
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The reasons for your study of English and the waysyou have been learning it doc
... traveling and learn more vocabulary on different aspects Standing before one of my historical vestiges, how can I tell my tourists about the history of my country and the courageous struggles of my ... I read in English the more words I can acquire to express my ideas and thoughts with great ease and satisfaction I have dreamed of becoming a tourist guide one day In order to realize this hope ... dictionary for English beginners Being aware of the preeminence of the English language in every aspect of man’s activity, I have been learning it with great zeal and avidity ...
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Báo cáo toán học: "Hard Squares with Negative Activity and Rhombus Tilings of the Plane" pdf
... to ρ, then the rhombus defined by the three corners x, y, z has area three and is hence not allowed If neither y nor z belongs to ρ, then we have another contradiction, as the region just to the ... product consisting of the linear polynomial t − and a number of factors of the form ts ± such that gcd(m, s) = Another of the main results of this paper is a proof of Conjecture 2; see Theorem 3.4 below ... = x and L i = c·(−1, 2)+(L−c)·(−2, 1) = i=1 i=1 y, it follows that x and y are integer multiples of the axes of the tiling This settles the other direction in the first part of the proof To compute...
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Báo cáo khoa học: "Clinical features and therapeutic management of patients admitted to Italian acute hospital psychiatric units: the PERSEO (psychiatric emergency study and epidemiology) survey" pot
... enrolment, and interpretation of analyzed data and to the review of this paper SF, AR, MS are current employees of Eli Lilly Italy, the study sponsor They contributed to the interpretation of analyzed ... Conversely, the percentage of drug abusers was quite low, even though it has been reported that the prevalence of comorbidity of psychosis and substance abuse has been rising during the last 10–20 ... during the acute phase of their illness At discharge, they usually receive therapeutic prescriptions and are no longer followed by SPDC structures, but by territorial services (some of which are...
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Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
... foci On the basis of the histological evaluation of the salivary glands performed according to the Chisholm and Mason classification [37], we could identify in patients with SS a total of 32 periductal ... separated T- and B-cell-rich areas), with or without ectopic GC-like structures identified on the basis of the histologic appearance and confirmed by the presence of FDC networks, as previously ... relationship with autoantibody production IL-18 is increased in the systemic circulation of autoimmune diseases such as RA and Crohn's disease, in which the principal site of production of this cytokine...
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Báo cáo y học: " Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study" potx
... participants stood barefooted on the analyzer and held the handgrips provided until the apparatus printed the results BMI was calculated on the basis of measured height and weight in kilograms per square ... intensity has been implicated in muscle wasting [10] by impairing the process of muscle protein synthesis [46] In contrast, in the present study, only very heavy smoking appeared to associate with ... lower BMI and BF compared with never-smokers Both BMI and BF were significantly increased in ex-smokers, whereas very heavy smoking appeared to associate with reduced FFM The study has several...
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Báo cáo y học: "Group cognitive behavioural therapy for women with depression: pilot and feasibility study for a randomised controlled trial using mixed meth" pptx
... feasibility of recruitment, assess the feasibility and acceptability of the group intervention and to make a preliminary assessment of its effectiveness This study encompasses Phases I and II of ... women with depression living in socially deprived areas in the United Kingdom The aims of this paper are to describe the development of the intervention and methods of data collection, ascertain the ... was involved in the conception and design of the project and some data interpretation JE was involved in the design and conception of the project RA jointly led the conception and design of the...
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Báo cáo y học: " The Brief Fear of Negative Evaluation Scale (BFNE): translation and validation study of the Iranian version" docx
... validity was carried out to demonstrate the extent to which the BFNE correlates with scores derived from the SPIN and the SIAS It was expected that the BFNE would positively correlate with these measures ... items, each with a 5-point Likert scale for answers The SIAS and the SPIN are used simultaneously to measure complementary aspects of social phobia The validation study of the SIAS resulted in ... and valid measure of social phobia However, since the scale showed a twofactor structure and this does not confirm to the theoretical basis for the BFNE, thus we suggest the use of the BFNE-II...
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báo cáo khoa học: " Stigma, social reciprocity and exclusion of HIV/AIDS patients with illicit drug histories: A study of Thai nurses'''' attitudes" pdf
... form of social control of deviance Unlike the social marginalisation of people on the basis of serostatus, the nurses appeared to side with the view of the wider community Whereas judgements within ... full and then translated into English Pseudonyms were assigned to each interviewee and the name of the nursing college remains anonymous The analysis of the data was conducted principally using the ... intentioned, they may lack the wherewithal to repay the social debt; or As a variation of point two, the potential recipient of the resource is regarded as too transient; i.e they may wish to repay the...
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Báo cáo khoa học: " Calcification of intervertebral discs in the dachshund: a radiographic and histopathologic study of 20 dogs" ppsx
... 19) to 24 (dog no 17) The individual number and location of calcified discs together with the degree of calcification of each affected disc, identified both by radiography and histopathology, are ... calcified discs in 79 (24.2%) of the dogs On the assumption that most of the dogs in the former study were dachshunds, these two studies together indicate that a radiographic study is far less sensitive ... Authors' contributions ØS conceived of the study, carried out the radiographic examination and is the main author of the paper ØK carried out the histopathologic examination Both authors read and...
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Báo cáo khoa học: " A morphological and molecular study of Anaplasma phagocytophilum transmission events at the time of Ixodes ricinus tick bite" pps
... to protocols provided by the DNeasy® Tissue kit Handbook (2004), with modifications as follows; The volume of Proteinase K was doubled and the incubation time with Proteinase K was extended to ... present study The endothelium has earlier been suggested to function as a transition site for Page of transfer of A phagocytophilum to neutrophils that are loosely bound and then released into the ... (44.7%) and appeared as intracytoplasmic aggregates, known as morulae The observed organisms were associated with leucocytes in the inflammatory infiltrate in the biopsies and were most often present...
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Validation of chemical looping with oxygen uncoupling (CLOU) using cu based oxygen carrier and comparative study of cu, mn and co based oxygen carriers using ASPEN plus
... below In the case of Copper and Manganese oxides, the overall reaction with carbon is exothermic in the fuelreactor as shown in equations (5) and (6) On the other hand the reaction of the Cobalt ... using ASPEN Plus These include the use of three different types of coal to determine their effect on the overall energy output, and the effect of varying the air flow rate on energy output and the ... in the air reactor to regenerate CuO from Cu2O Another compressor is used to compress the steam for the gasifier There is large amount of energy produced in the air reactor, but the fuel reactor...
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The generation and experimental study of microscale droplets in drop on demand inkjet printing
... Xing, Shareen Chan and Lim Wei Ren Farand They have all worked together with me and given me great help in the development of my research project They are also my friends and made my graduate study ... center of the cell to the center of the dried droplet The “Radius” is the radius of the dried droplet “Rcell” is the radius of the round-shaped L929 rat fibroblast cells, which has a value of approximately ... between the speed of the fine-jet and other parameters like the diameter of the jet and the physical properties of the liquid, were also characterized The study provides a possible way to improve...
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A field and geochemical study of the boundary between the nanga parbat haramosh massif and the ladakh arc terrane, northern pakistan
... (1933,1937), the nature of the eastern boundary was obscure The purpose of this study is to define the location and character of the eastern boundary of the Nanga Parbat massif The eastern margin of the ... blueschists, and greenstone assemblages The eastern and western boundaries of the massif trend north/ south and have been drawn as extensions of the Indus Tsangpo suture and MMT The southern part of the ... is in northern Pakistan in the region referred to as the Deosai Plateau (Fig 1.2) The western border of the study area is at the town of Shengus, 45 km east of Gilgit, and The the eastern border...
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Experimental investigations and CFD study of temperature distribution during oscillating combustion in a crucible furnace
... of the hot gases 10 cm away from the inner walls of the combustion chamber of the furnace T3 = Temperature of the hot gases at the entry of the stack 2.2 Model geometry and mesh The geometry of ... distribution in the load during the heating and cooling periods is of interest for the design of the furnace and the metallurgical control of the process [9] An approach based on the assumption of periodicity ... important to ensure the thermal energy of the hot gases to be absorbed by the load and the furnace walls Temperature distribution in the furnace is paramount for the optimization of the thermal...
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