... Solution -Phase Synthesisof Substituted Amines by N-Alkylation with %-Halocarbonyl CNLONSMDQZZZZZZZZZZZZZZZZZZZZ'''13 1.3 Examples of Solid- PhaseSynthesisof Substituted AminesZZZZZZ'ZZZ.18 1.3.1 Solid- Phase ... August 2010, Solid- PhaseSynthesisof N-Carboxyalkyl Unnatural Amino Acids Major Professor: Martin J 9^/NMMEKl, Ph.D A novel route has been developed for the solid- phasesynthesisof Ncarboxyalkyl ... Title of Thesis/Dissertation: Solid- PhaseSynthesisof N-Carboxyalkyl Unnatural Amino Acids Master of Science For the degree of I certify that in the preparation of...
... xiv LIST OF PUBLICATIONS CHAPTER 1: INTRODUCTION 1.1 Solid- phasesynthesis (SPS) 1.1.1 Solid supports 1.1.2 Linkers 1.1.3 Reaction monitoring in solid- phasesynthesis 13 1.1.4 Solid- phase synthetic ... from the solid support (Figure 1.1) Figure1.1 Illustration of a solid- phasesynthesis This concept of solid- phasesynthesis was first raised by R B Merrifield in 1963 for efficient peptides synthesis. [1] ... thesis reports the development of novel methodologies for the solid- phasesynthesisof purine derivatives The first project involves the solid- phasesynthesisof 2,9-disubstituted-6-oxopurines...
... Abstract—a-Acylamino-a,a-disubstituted ketones are of interest as ecdysone agonists Solidphasesynthesisof prototypical a-acylamino-a,a-disubstituted ketones on two different solid supports is described In both ... 1).1,2 To investigate this hypothesis we sought a solidphasesynthesisof which would be sufficiently general to allow production of a library of compounds for biological screening Figure a-Acylamino-a,a-disubstituted ... anhydride of 6a, prepared in situ by treatment of 6a with 0.5 equiv of DIC in a mixture of CH2Cl2 and DMF (entry 9).27 Submitting the resin to a second cycle of coupling increased the level of conversion...
... 23 iv TABLE OF CONTENTS 2.2.3 Solidphase crystallization (SPC) of a-Si:H films 30 2.2.4 Rapid thermal annealing of poly-Si thin films 31 2.2.5 Hydrogenation of the poly-Si thin ... 131 6.3.1 Effect of SiH4 gas flow rate on the deposition rate of a-Si:H films 131 6.3.2 Effect of RF power density on the deposition rate of a-Si:H films 134 6.3.3 Effect of SiH4 gas flow rate ... representation of the interdigitated metallisation scheme of poly-Si thin-film solar cells on glass (b) Schematic xii LIST OF FIGURES cross-section of an emitter finger, the sloped sidewalls, and parts of...
... values) Synthesisof benzodiazepines Rachedine Kaoua et al Molecules 2011, 16, 92-99 Synthesisof benzodiazepines Sternbach et al J Org Chem 1962, 27, 3788 Lednicer et al Organic Chemistry of Drug Synthesis; ... New York, 1998 Lednicer et al The Organic Chemistry of Drug Synthesis; Wiley-Interscience: New York, 1977 Ellman’s solid- phasesynthesisof 1,4-benzodiazepines Ưu điểm Tổng hợp Pha rắn? Không ... PHA RẮN TỔNG HỢP PHA RẮN SOLIDPHASESYNTHESIS • The scale SPS is limited and restricted by the amount of the solid support and its loading capacity • The preparation of multi-milligram quantities...
... 15] Synthesisof nanostructures via simple wet-chemical method is one of the most favoured routes towards the cost-effective large-scale production of nanobuilding blocks Chemical synthesisof ... with a very few number of spheres The histogram of nanodiscs distribution (Fig 2b) shows that majority of discs have a diameter of *55 nm On the other hand, HR-TEM photograph of green-coloured silver ... 1c), obtained by using mM of sodium citrate, shows the presence of only silver nanorods of different aspect ratios (R = 3–7) The histogram of particle distribution of corresponding silver nanorods...
... serum of α1AGP and of haptoglobin, and also of mRNAs of acute phase proteins to a level as found in the control animals Furthermore, that the BDL cirrhosis model itself triggered the synthesisof ... models The acute phase response consists of changes in the serum concentration of multiple proteins due to a reorganization of hepatic protein synthesis favouring "the acute phase proteins" and ... mortality of patients with cirrhosis exposed to infection is rooted in a decreased liver function in the form of a decreased synthesisof acute phase proteins In addition, that the function of the...
... technique can be used for solution as well as solidphasesynthesis diversification reaction divide diversification reaction Split-pool Synthesis • Optimization of reactions leads to compounds • Each ... the β-elimination of resin-bound leaving groups has been used as a cleavage strategy for the release of alkenes from supports Preparation of Alkenes by β-Elimination Preparation of Alkenes by β-Elimination ... C-Vinylation The Heck, Stille, and Suzuki couplings Synthesisof tetrahydroisoquinolines Parallel Library Synthesis • Optimization of 12 reactions provides compounds • The library members...
... effects of pH of the aqueous Table Because the flow rates of sample solution and eluent solutions are two important parameters for the quantitative retention of analytes on the solidphase extraction ... is not used for the solidphase extraction studies In this work, a simple and accurate procedure for cadmium(II) and lead(II) ions that is based on solidphase extraction of cadmium(II) and lead(II) ... Natural and synthetic solidphase extractors that have high surface area and adsorption capacity, stable for acidic and basic media are preferred for solidphase extraction of metal ions Zeolites,...
... described here: solidphase crystallization (Section 1.3.1), seed layer approach (Section 1.3.2), and liquid phase crystallization (Section 1.3.3) 1.3.1 Solidphase crystallization The solidphase crystallization ... Investigation of impact of HF:HNO3 acid ratio on scattering efficiencies of AIT glass 47 3.2.4 Up-scaling of the AIT process to pilot line-scale borosilicate glass sheets 50 3.3 Fabrication of ... Figure 6-3: (a) SEM tilt view of sample RST4, (b) SEM cross-sectional view of RST4 111 Figure 6-4: The AFM measured height profiles of the rear Si surface of (a): sample RST4 after...
... successful realization of this thesis iii TABLE OF CONTENTS ACKNOWLEDGEMENT i TABLE OF CONTENTS iii SUMMARY vii LIST OF PUBLICATIONS x LIST OF TABLES xi LIST OF FIGURES xiii LIST OF SYMBOLS xv CHAPTER ... Application of the silica monolith as solidphase extraction cartridge for the extraction of epinephrine, metanephrine and normetanephrine from urine Application of the silica monolith as solidphase ... dealt with the solidphase extraction and this thesis is dedicated to explore the potential of monolith as a solidphase extraction cartridge Chapter 24 1.6 MONOLITH: AS A SOLIDPHASE EXTRACTOR Sample...
... Figure 1.2 Evolution of number of transistors packed into each of Intel’s new generation of microprocessors, describing Moore’s law [2] .3 Figure 1.3 Cost of fabrication of transistors, DRAM ... leakage profile of the various diodes fabricated The change in the slope of the leakage profile at a bias larger than 2V is due to the onset of GIDL current 83 Figure 5.8 XTEM images of the ... half that of the influenza virus or about 2000 times smaller than a strain of human hair For a sense of the physical size of the transistor, Fig 1.7 shows a micrograph image of a strand of hair...
... behavior ofsolid materials is largely dependent on the mineralogical characteristics of the solidphase (Ettler et al 2003), the second objective involves identification of possible mineralogical phases ... variety of phases, namely phases with high Zn-Ni-P-Fe and phases with high Al-Si content The coexistence of Zn, Ni, P, and Fe, as observed in the map, suggests that Fe and PO43−-rich phases are ... SE) and therefore supports in direct solidphase characterization The results ofsolidphase characterization can be used to account for the leachability of some HMs (e.g., Ni and Zn in sample...
... portion of body or tail of the pancreas For tumors of SPT located in the neck and body of the pancreas, resection of the midportion of the pancreas and the mass with preserving the rim of the ... Malignant potential ofsolid pseudopappillary neoplasm of the pancreas Br J Surg 2006;93:733-37 de Castro SMM, Singhal D, Aronson DC, et al Management of Solid- pseudopapillary Neoplasms of the pancreas: ... analysis of solid- pseudopapillary tumor of the pancreas: report of 15 cases Hepatobilliary Pancreat Dis Int 2008;7(2):196-200 Yu CC, Yeh CN, Hwang TL, Jan YY Clinicopathological study ofsolid and...
... regardless of SHW feeding rate The most important impact of the SHW feeding was on the free lime content of the clinker Replacement of 20% of the coal energy in the rotary kiln burner (3 t/hr of SHW ... inlets for solid and liquid alternative fuels and one annular inlet for coal, see Figure 1(b) The solid alternative fuel is fed via a Pfister feeder system designed to control mass feeding ofsolid ... distribution 4.2 Analyses of raw meal, precalcined meal and clinker The variation of the measured raw meal properties during the test period was insignificant The degree of calcination of the precalcined...