... be the reference); 2, docked into the active site of the human DPP-IV; 3, docked into the active site ofthe crystalline structure of PepX from L. lactis;and4, docked into the active site ofthe ... Sites forthedesignof inhibitors of PepX activityFEBS Journal 272 (2005) 2050–2059 ª 2005 FEBS 2051 The structural comparison ofthe bacterial PepX andhuman DPP-IV reveals sites forthedesign ... 2). The interactions ofthe bound ligand with the resi-dues ofthe specificity site (Fig. 4A) reveal good stack-ing between the pyrrolidine ring ofthe drug and the side chain of Tyr380 (Pos1 subsite),...
... together to form long chains of -CH2-.[75] There has been disagreement over the exact reaction and order ofthe reactions since the 36 Figure 9: Product distribution for different α forthe ... From the calculations derived in Appendix A, the energy demand forthe modified pulping section ofthe plant is 56 MW of electricity and 267 tonnes per day of steam. The demand forthe steam ... intermediate. The first part ofthe reaction from synthesis gas to methanol is quite exothermal and it is limited by equilibrium at a fairly low temperature. Therefore, the first part of the reaction...
... on theoretically sound grounds, we argue that, given the state ofthe art, the only viable solution forthe designer of software tools for MT, is to provide the linguists building the ... in charge of redesigning the system whenever new needs forthe user arise. Therefore the part ofthe system that is visible to the linguistic user will be a system generator, rather than ... of an MT system. B. Computational Paradigm for MT Software The computational paradigm we have chosen for the systems to be generated is the one of expert systems because thedesignof software...
... Followingsanitation, the vehiclemustbeallowedadequatedryingtimeafterdisinfection.Aswithfacilities,thisis the mostimportantstepin the sanitationprotocoltocompletelyinactivate the virus. The use of highvolumewarmaircandecrease the amount of timeneeded for drying. The thermoassisteddryinganddecontamination ... itoescanserveasmechanicalvectors of PRRSVandcantransport the virusatleast2.4kmfromaninfectedfarm. The site of retentiono f the virusin the flyis the GItractand the rate of viraldecayovertimeisinfluencedbyquantityingestedandenvironmentaltemperature.Inordertopreventspread of PRRSVviainsects the followingstepsarer ... receivesemenvalidatedasPRRSVnegativeinrealtimeandsafelyintroduceittotheirherds.BloodtestingisoweangiltsinquarantineIndirectroutesPRRSVcanbemechanicallytransmittedinanumber of ways. The follow ingsectionwillreviewroutes of transmiss ionandoutline the biosecurity protocols designedtohelpprevent spreadviatheseroutes.13v Once the evacuationperiodisover,...
... and all ofthe devices forthe new platform will CHAPTER 1 ■ WINDOWS MOBILE AND .NET 6 These emulators actually offer a full implementation ofthe emulated device and are capable of running ... with the rest ofthe device to avoid irritating your user. There are a number of things we can do to reduce the impact of this type of interruption: automatically pause the game if another ... Windows CE forms the underlying platform for Windows Mobile devices. These use many ofthe features and services provided by the core operating system, but add a significant amount of additional...
... form of subject-verb agreement. Note that the process of unification is order-independent. For instance, we would get the same effect regardless of whether the unifications at the top ofthe ... requires that the agr feature ofthe DAG associated with the VP be the same as (unified with) the agr of the V. Thus, the VP's agr feature will have as its value the same node as the V's ... the application ofthe rule. The grammar rules describe how constituents can be built up to form new constituents with associated DAGs. The right side ofthe rule lists the cat values of the...
... Þres:a. The time ofthe ÞreÕs inception if there is ßame impinge-ment or engulfment ofthe vessel.b. The liquid level in the storage vessel and whether it isabove or below the area of ßame ... determination ofthe distance between the vessel and the center ofthe pool Þre at which the maximum incident heatßux to the vessel shell surface will be at the critical value of 7000 British thermal ... holesto the side ofthe vessel or to grade.2.10.2.4 The vertical stack from the valve should be sup-ported independently ofthe valve. Otherwise, the ßow reac-tion forces can impose stresses on the...
... This information includes, for example, the kind of clause (main, coordinate, subordinate), whether the clause has a verb to be solved, the voice and form ofthe clause, the kind of event ... hypotheses about their causes. On the basis of these hy- potheses, the Tutor selects the next exercise which will test the student on the critical aspects pointed out so far and will allow the ... employed for producing it. At this point, the Student Modeler compares the answer ofthe student with that ofthe expert in order to identify the errors, if any, present in the former and to formulate...
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... did the final approval ofthe manuscript. MK, MP, LMcN, TC, JY, KO andAH were driving the conception and designofthe study, selected the donors forthe study, interpreted the data and wrote the ... incollaboration with the CIC executive office and the steering committee ofthe CIC Immunoassay workinggroup. The authors of this group acknowledge the con-cept ofthe Minimal Information About ... S2Acknowledgements The organizers of this study are indebted to all the participating labs for their constant support ofthe proficiency panel program. The organizers alsothank Beckmann Coulter and ProImmune for...
... did the final approval ofthe manuscript. MK, MP, LMcN, TC, JY, KO andAH were driving the conception and designofthe study, selected the donors forthe study, interpreted the data and wrote the ... incollaboration with the CIC executive office and the steering committee ofthe CIC Immunoassay workinggroup. The authors of this group acknowledge the con-cept ofthe Minimal Information About ... using the irrelevant MULTIMERS in four donors stratified byDUMP channel use and further subdivision by the use of dead cell marker. The table also indicates the number of labs (N) for each of the...