... less sensitive to the pres-ence ofthe anion. These residues also modulate the conformation of unfol-ded cytochrome c, influencing its spin state and the coordination to the prosthetic group.AbbreviationCT, ... affect the structure and the functional properties ofthe protein, as the con-served lysine-rich domain around the solvent-exposedheme edge is involved in the interaction with redoxpartners. The ... expressionsystemA version ofthe horse cytochrome c synthetic gene wasdesigned on the basis ofthe sequence of a previously repor-ted cytochrome c synthetic gene [35], and its synthesis wasaccomplished...
... 17 ofthe Act concerning the conditions of Accession ofthe Czech Republic, the Republic of Estonia, the Republic of Cyprus, the Republic of Latvia, the Republic of Lithuania, the Republic of ... III(4) ofthe Treaty of Amsterdam. 1345.2. The General Council shall comprise the President and Vice-President ofthe ECB and the Governors ofthe nationalcentral banks. The other members ofthe ... established, the President, the Vice-President and the other members of the Executive Board shall be appointed by common accord ofthe governments ofthe Member States at the level of Heads of State...
... irrespective ofthe amount ofthe loan. However, the larger the loan, the larger the amount ofthe repayment installment, and a large installment may strain the repayment capacity ofthe borrower ... b) There has, therefore, to be a linkage between the amount ofthe loan and the tenure ofthe loan. It is, therefore, suggested that for loans not exceeding Rs. 15,000, the tenure ofthe loan ... explore the use of outside agencies for inspection. e) The Reserve Bank should have the power to remove from office the CEO and / or a director in the event of persistent violation of the regulations...
... high: the number of consultations per capita is higher in Japanthan in any other OECD country [9], and the rates of hospital utilization are high as well. These trends havemade the shortage of ... resolve shortages of healthprofessionals by actively recruiting doctors from othercountries. In the 1990s, for example, when the UnitedKingdom was facing a shortage of doctors, the National Health ... Table 5. Themain outcome measurewas the number of medical doctors per 1000 persons.Simulation scenariosWe used this simulation to project the number of medi-cal doctors under each ofthe following...
... and 42 (8%) of unknown gender.It was the mother who answered the questionnaire in89.5% ofthe sample, it was the father in 4.57% of the sample, and it was someone else in 6.28% ofthe sample.Distribution ... SummaryScore, the mean is computed as the sum ofthe itemsdivided by the number of items answered in the Emo-tional, Social, and School Functioning Subscales. The sequenti al validation procedure ofthe ... Varni4, Gábor Mogyorósy1Abstract Objectives: The aim ofthe study was to investigate the psychometric properties ofthe Hungarian version of the Pediatric Quality of Life Inventory™ (PedsQL™) Generic...
... Magnitudes in the correlations of all DQOL domains with the physical relevant domains of the D-39S (diabetes control and energy/mobility) wereslightly larger than with other domains ofthe D-39S(social ... approaches, the range of MIDs were 3–5 points for the satisfaction domain, 4–5 points for the impactdomain, 6–8 points for the worry domain, and 3–4 pointsfor the overall HRQOL.DiscussionAlthough the ... satisfaction domain ofthe DQOL with diabe-tes control and energy/mobility ofthe D-39S were all0.57, which were larger than with the other D-39 domains(0.30 through 0.46). Magnitudes in the correlations...
... toxicity of chemotherapy or the isolation to which the individual is subjected [9,15]. The analysis ofthe correlation between the scores the chil-dren/adolescents obtained and those obtained by the guardians ... hospitals ofthe city. A total of 190 families of Bra-zilian children between the ages of 2 and 18 years, of bothgenders, with malignant neoplasm in various phases of treatment or control ofthe ... related to the small number of items that compose the subscale [22]. Furthermore, Alpha Coefficient values maybe influenced by the level of schooling in the sample [23]. The analysis ofthe Corrected...
... Comparisons to the mean scores of the other subscales within the present study to those of the previous PedsQL™ school study [3], the mean scoreson the social functioning scale of both healthy ... respondents in the way it wasintended by the developer ofthe scale [15]. Thus, the assumptions about both the quality ofthe measures andutility ofthe rating scale in facilitating interpretable ... [20,21]. Range of measurement was fur-ther tested based on the percentage of scores at the extremes ofthe scaling range, that is, the maximum possi-ble score (ceiling effect) and the minimum...
... well as the proportions of respondentsreporting impairment in the 5 EQ domains. The magni-tude and significance ofthe ORs for the EQ-5D domains,as well as the sign and significance ofthe regression ... applicability. The primary goal of our study was to assess the applicabil-ity, internal consistency, and construct validity ofthe Ital-ian version ofthe EQ-5D in a random sample of the citizens of Bologna ... set-tings, it lacks of empirical evaluations in Italy. The lack of information on the construct validity and reliability of the instrument as well as the absence of utilities estimated in the Italian...
... now, validation ofthe Japanese ver-sion has not been conducted. The aim of this study was to demonstrate the reliabil-ity, validity, and feasibility ofthe Japanese version of the PedsQL 3.0 ... demonstrate the feasibility of the Japanese version ofthe PedsQL 3.0 Cancer Module.Discussion The present study demonstrated t he reliability, validity,and feasibility ofthe Japanese version ofthe ... low in the validation study ofthe Chi-nese version [17]. The German and the Brazil ian ver-sions ofthe PedsQL Cancer Module did not report the analysis for separate age groups. However, the...
... the RAND CorporationView document detailsFor More InformationThis PDF document was made available from www.rand.org as a public service of the RAND Corporation.6Jump down to document THE ... WORKPLACE The RAND Corporation is a nonprofit research organization providing objective analysis and effective solutions that address the challenges facing the public and private sectors around the ... later in this work. This electronic representation of RAND intellectual property is provided for non-commercial use only. Unauthorized posting of RAND PDFs to a non-RAND Web site is prohibited....
... and the specific wording ofthe biblical rules ofthe goring ox is so close to that ofthe cuneiform antecedents that any explanation ofthe resem-blances other than one based on some kind of ... experience, and then became quite independently the source ofthe goring-ox laws ofthe Book of Exodus.75He left the exact source undefined: the biblical rules derive their inspiration from these earlier ... Introduction: The Basic Thesis and Background 15 of the epilogue otherwise presumably facilitated CC’s use ofthe essence of this later transitional introduction in the formulation of 21:1.In the broader...
... adjacent to the putative fusogenic domain of HBV suggests that the viral infection probably is the consequence ofthe exposure of HBV fusion domain (Figure 1 B) [5,6]. The proteolysis to make the viral ... translocation ofthe internally sequence of PreS1 domain onto the viral surface [62, 63]. This supports the hypothesis that the low pH in the endosome may induce the conformation change of HBV surface ... a result ofthe variation of loading, because the expression ofthe thimet oligopeptidase gene in the same condition did not show any difference (Figure 2C). The over-expression ofthe SPIK...