... from the rest of the pack. They are in a position to view their marketing mix in the form of 4+1P and 1R, and thereby customize their offerings to the rural market. Further, to ensure a wider ... handpumps and ponds. For the first in the history of advertising - these were branded. Special stickers were put on the handpumps, the walls of the wells were lined with advertising tiles and ... some of the products. Andthe red-faced marketers admit that they actually sell their products in areas they would otherwise find difficult, simply because there are other uses for them. For...
... for binding GST-IjBa in the presence and absenceof ATP, andthe value of a indicates whether the bindingof one substrate (ATP) affects the affinity of the enzymefor the other substrate (GST-IjB ... the plot shows the number of repeats. Phosphorylation of tagged IjBa (d; A) and auto-phosphorylated rhIKK2 (j; B) is shown. In (A), s is the control assay, and in (B), s and D represent the control ... andthe plates left to incubate for15 min. The plates were inverted to remove the detergentafter the 15 min incubation period andthe wells werewashed twice with wash buffer by inverting the...
... the interactions betweenthe components of abiological system, andhow these interactions give riseto the function and behaviour of that system (forexample, the enzymes and metabolites in a metabolicpathway). ... that FBA does provide a good estimate to the realfluxes through the system as predicted by Teusinket al. The discrepancy betweenthe real and FBA solu-tion is due to FBA disregarding the branches ... ethanol concentration. Shown are the real model solutions (o), andthe pre-dictions of the linlog model with both estimated (solid line) and correct (dashed line) fluxes and elasticities. ADH,...
... region andthe cytochrome bextramembranous cd2 helix is important for maintaining the structure of the hinge region and, by consequence, the movement of the headgroup andthe integrity of the enzyme.Keywords: ... ISP and the extramembranous cd2 helix of cytochrome b areimportant for maintaining the structure of the hinge region and, by consequence, the movement of the headgroup and the integrity of the ... in favour of aneffect of the G167E mutation on the movement of the ISP, and not on the Qosite structure. However, the EPR signal in the presence of reduced quinol and stigmatellin was modified,suggesting...
... particular, the key interaction between the ligand andthe receptor was determined to be the ionic interaction involving the ligand’s TyrNH and Asp147 of TMH III, as reported for several otheropioid ... description of the binding mode andthe electronic and steric proper-ties of the c[YpwFG] ligand.ResultsSynthesis and pharmacological characterizationof the cyclopeptides c[YpwFXaa]We synthesized ... Cys and His) located on the surface of the bind-ing site, and this polarization effect can be obtained byusing the QM description of the ligand. Looking at the electronic structure of the ligands...
... they showed a markedly longerlifetime. Comparison of two-dimensional HSQC and NOESY spectra of MNK5 with and without the poly(His)tag shows that there is no detectable interaction between the ... high-resolutionNMR the interaction between HAH1 and two differ-ent soluble domains of ATP7A: the second (MNK2hereafter) andthe fifth (MNK5 hereafter). The solu-tion structure of both the apo- and copper(I)-form ... differentiation between the first four (counting from the N-terminus) and the last two domains, and suggest that the last twodomains are sufficient for function [12–14]. In addi-tion, the mechanism...
... substantiverevisionsto the Criteriafor2008.(NIST,2008,p.27) The mostsignificantchangesin the 2008bookletinclude the additionof the term“StrategicAdvantages”to the GlossaryofKeyTerms, and twonewdiagrams–oneofwhichillustrates the roleofcorevalues and conceptsinunderpinning the criteria, andthe othershowsmaturitylevelsinorganizationallearning(NIST,2008).Therefore, the 2007framework and the 2008frameworkcanbeusedinterchangeably. The relationshipsin the proposedconceptuallyenhanced2007/2008frameworkarecurrentlynotvalidatedin the academicliterature.Validating the 2007/2008frameworkwillsupport the framework’scurrentformaswellasprovidemanagerswithmeaningfulinformationthattheycanuseindecidingwheretheyshouldfocustheireffortsinachievingperformanceexcellence.Therefore, the firstobjectiveofthisstudyistovalidate the underlyingrelationshipspresentedin the 2007/2008framework. The MBNQAframeworkenjoyswidespreadacceptanceatlocal,national, and internationallevels(Kochan,1992;Ettorre,1996;Pannirselvam,Siferd,&Ruch,1998).Variousstudieshaveused,extended and testedthisframeworkinseveralindustries,suchashealth3 ... resultinatotalof1950propositions(30+64ì30=1950).RecallthatthisstudyexaminesthreeresearchmodelsandthatoneistheMBNQAframeworkatthecategorylevel.AnothermodeladdressestheMBNQAframeworkatthedimensionlevel.ThissectiondiscussesthecategorylevelMBNQAframework.However ,the resultscategoryoftheMBNQAframeworkistoobroadtoallowsubstantivediscussionatthecategorylevel.Thus,fortherecursivecausalmodelatthecategorylevel,theresultscategoryissplitintoitssixcomponents.Nonetheless,thecausalityamongtheoutcomesisleftforconsiderationatthedimensionlevelframework.Eachsystemcategoryembodiessixrecursivecausalrelationshipswiththeoutcomes.However,eachoftheserelationshipscanbemediatedbyuptofivesequentialsystemcategories,producing325mediations.Thiswillresultin11,700propositionsaboutthemediatingrelationships.37 ... the utilizationofavailableresources(NIST,2008).3.1Customer and marketknowledge The processtounderstand the needs and expectationsofcurrent and futurecustomers and markets(i.e., the processtounderstand the voiceof the customer and market)(NIST,2008).3.2Customerrelationships and satisfaction The processtoestablishcustomerrelationships, and toascertaincustomersatisfaction and dissatisfactioninordertoretain the currentcustomers, and acquirenewcustomers and newmarkets(NIST,2008).4.1Performanceanalysis,review and improvementEffectiveselection and useoffinancial and non‐financialdata and informationtoanalyze,review, and improveorganizationalperformancewithaviewtowardachievingstrategicobjectives and toprepareforunexpectedorganizationalorexternalchanges(NIST,2008).4.2Data and knowledgemanagement The development and managementofknowledgeassets(e.g.,allsortsofdata,information,software and hardware)toimproveorganizationefficiency and effectiveness(NIST,2008).5.1Workforceengagement The mechanismthatengages,develops, and assessesanorganization’sworkforcetofosterhighemployeeperformance and toenable and encourageemployeestocontributeto the achievementofstrategicobjectives and organizationalsustainability(NIST,2008).Continued13...
... findings show that there is a relationship betweenthe gender and postcode area of students with the feeling safety when they use the Safety Bus. It means the genders and postcode area affect the ... (x1=distance-home,x2=distance-public and x3=rent). The scatter diagrams can present the association between two variables at one time (x1 and y; x2 and y; x3 and y; and x4 and y). The intensity of the relationship ... 392.0 The table above gave the as the explanation for the differences betweenthe pragmatic and expected account. Female students feel threatened when they go round the city during the night rather...
... HOW TO BRIDGE THE DISTANCE BETWEEN BUSINESS STRATEGY AND DESIGN FINALLYA brand is not a product. A VISUAL PRESENTATION BY MARTY NEUMEIER The three most important ... information. READY? In other words… THE FOCUS TEST:Who are you?What do you do?Why does it matter?123 THERE ARE 1,349 CAMERAS ON THE MARKET. HOW DO YOU DECIDE WHICH ONE TO BUY? BRANDNAMECOCA-COLAMICROSOFTIBMFORDMERCEDESHONDABMWKODAK GAP NIKEPEPSIXEROXAPPLESTARBUCKSTHIS ... for whichpeople believe there’s no substitute. SOLUTION:BE DIFFERENT. IT’S NOT WHAT YOU SAY IT IS. AND HOW. A modern definition of brand The five disciplines of brand-buildingWHAT YOU’LL...
... DELL FIRSTA brand is not a logo. FOCUS1 AND HOW. $ Does a brand have a dollar value? FOCUS3 A VISUAL PRESENTATION BY MARTY NEUMEIER DISCIPLINE 1: DIFFERENTIATE ON SUNDAYS THEY WORSHIP ... BOOKSEVEREADYFORDGENERAL ELECTRICGOOGLEHANES FOCUS2 DOESTHE LEFT BRAIN KNOW WHAT THE RIGHT BRAIN IS DOING? But first, you have to master the FIVE DISCIPLINES OF BRAND-BUILDING. Marketing today is about ... do?Why does it matter?123 IT’S WHAT THEY SAY IT IS. On one side of the gap are STRATEGIC THINKERSANALYTICALLOGICALLINEARNUMERICALVERBALOn the other side areCREATIVE THINKERSINTUITIVEEMOTIONALSPATIALVISUALPHYSICAL...