histology cellular phenotype k ras mutations and cell kinetics in gastric intestinal metaplasia in patients with chronic gastritis and gastric cancer
Báo cáo y học: "Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysi" ppsx
... LipopolysacchaLipopolysaccharide-induced intracellular cytokine expression in monocytes and myeloid dendritic sepsis sepsis ride (LPS)-induced intracellular cytokine expression in monocytes and in myeloid dendritic cells ... and TLR9 agonist-induced cellular responses in MDCs and PDCs in patients with sepsis In line with previous findings, we found increased IL-10 levels in septic patients at baseline and at day 28 ... leukocytes Intracellular cytokine staining by flow cytometry For flow cytometric measurement of intracellular cytokines, heparinized blood samples were diluted 1:1 in RPMI without supplements and...
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Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx
... regulatory T cell (Treg) levels by week in the 22 patients with melanoma treated with interferon-a 2b (B)Box plot showing circulating regulatory T cell (Treg) levels by week in the 22 patients with melanoma ... factor-b, interleukin-10 and autoantibody in interferon-a 2b-treated patients with melanoma (A) Transforming growth factor-b (TGF-b), (B) interleukin (IL)-10, and serum autoantibodies: (C) antinuclear ... week in patients treated with IFN-a 2b are shown in Figures 4A (individual patients) and B (all patients) For individual patients (Figure 4A), 14 of 22 (63.6%) patients showed a decrease in Treg...
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Báo cáo y học: "Identification of target antigens of antiendothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach" potx
... HUVECs Vinculin is a cytoskeleton protein involved in extracellular matrix adhesion and intercellular junctions by binding to actin filaments This protein has several interaction sites with numerous ... of vinculin spots displayed in (A) binding partners, including a-actin [39] Changes in the relative content of vinculin and a-actin have been reported in the human aortic intima of patients with ... shock 27-kDa protein 1; IL4: interleukin 4; IMPDH2: IMP (inosine 5-monophosphate) dehydrogenase; IRS1: insulin receptor substrate 1; KHSRP: KH-type splicing regulatory protein = FUBP2; LMNA: lamin...
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Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... combined navelbine and mitoxantrone, supporting the testing of combination therapy with estramustine, mitoxantrone, and vinorelbine in patients with CRPC One study demonstrated a potential clinical benefit ... treatment with vinorelbine, mitoxantrone and estramustine yielded a response rate suggesting clinical activity in men with CRPC, and was well tolerated The combination of CRA/IFN and paclitaxel, in ... with a clinically meaningful decline in QOL at week 9/10 compared with baseline [16] However, Bcl-2/actin ratios decreased in PBMCs with therapy, supporting further study of this as a marker of...
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Báo cáo sinh học: "Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-g in patients with chronic heart failure" potx
... technologies, Luminex and Mesoscale Discovery, for human cytokine profiling J Immunol Methods 2009, 340:55-64 23 Inoue T, Komoda H, Nonaka M, Kameda M, Uchida T, Node K: Interleukin-8 as an independent ... ovals), are linked to each other in terms of expression and/ or function (black thick lines), and to a number of molecules, namely Norepinephrine, Endothelin-1, IL-1A, Galectin-3, TNFa, IL-6 and IL-18 ... biomarkers The biomarkers found in heart failure include BNP, NT pro-BNP, C-reactive protein, tumor necrosis factor a, interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin,...
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báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot
... HADS Patients completed the self-administered and validated German version of the HADS[19] The HADS measures depression and generalised anxiety in in- and outpatients and in community settings ... approximately 1.5 points in COPD patients Investigators and those interpreting clinical research can use this minimal important difference to determine whether treatment effects are in a range that ... Zee JS, Schade E: Risk of depression in patients with chronic obstructive pulmonary disease and its determinants Thorax 2002, 57(5):412-416 Kunik ME, Roundy K, Veazey C, Souchek J, Richardson P,...
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báo cáo hóa học:" Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-g in patients with chronic heart failure" pptx
... technologies, Luminex and Mesoscale Discovery, for human cytokine profiling J Immunol Methods 2009, 340:55-64 23 Inoue T, Komoda H, Nonaka M, Kameda M, Uchida T, Node K: Interleukin-8 as an independent ... ovals), are linked to each other in terms of expression and/ or function (black thick lines), and to a number of molecules, namely Norepinephrine, Endothelin-1, IL-1A, Galectin-3, TNFa, IL-6 and IL-18 ... biomarkers The biomarkers found in heart failure include BNP, NT pro-BNP, C-reactive protein, tumor necrosis factor a, interleukins and 6, TNF-a, matrix metalloproteinases, neuroepinephrine, renin,...
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báo cáo hóa học:" Comparison of numerical and verbal rating scales to measure pain exacerbations in patients with chronic cancer pain" ppt
... defined as "consistent" if background pain intensity was lower than peak intensity, otherwise it was defined as "inconsistent" (background pain intensity higher than or equal to peak pain intensity) ... contained a double evaluation both for background pain and for pain intensity exacerbations; one evaluation was performed using a 6-point VRS and patients were asked to rate their pain intensity ... background and peak pain intensities (Δ) for each of the 158 patients who reported to have had pain exacerbations in the previous 24 hours, when using VRS and NRS; when Δ ≤ (i.e background pain...
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Báo cáo y học: "Altered dendritic cell distribution in patients with common variable immunodeficiency" pot
... along with JFV, in charge of most of the CVID patients gathered in this study and contributed to the writing of the article MA and FL were in charge of CVID patients and contributed to the writing ... Touraine JL, Peronne G, Tovo PA, de Vries JE: Peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) produce reduced levels of interleukin-4, interleukin-2 and interferon-gamma, ... 17:235-238 Jego G, Palucka AK, Blanck JP, Chalouni C, Pascual V, Banchereau J: Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin Immunity 2003,...
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Báo cáo y học: "The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus" potx
... mean cpm obtained in cultures incubated in the absence of antigen An SI ≥3.0 and a ∆cpm >1,000 (mean cpm obtained in cultures with antigen minus mean cpm obtained in cultures incubated in the absence ... JF, Krainer AR: Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins EMBO J 1994, 13:5483-5495 Carson JH, Kwon S, Barbarese E: RNA trafficking in myelinating cells Curr Opin ... phytohemagglutinin and 20 U/ml IL-2 in medium containing 1% heat-inactivated human AB serum Growing microcultures were then expanded at weekly intervals with fresh feeder cells in the presence of...
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Báo cáo y học: "Serological and molecular expression of Hepatitis B infection in patients with chronic Hepatitis C from Tunisia, North Africa" pdf
... respectively Seven patients had mixed infections: 1a and in cases, 1a and 1bin cases and 1a and in one case The viremia levels for HBV and HCV in the studied patients and controls, according to their ... between individuals with single HBV infection and HCV/HBV co-infected patients revealed significantly lower viremia levels in the second group than in the first one (Figure 1A) These findings indicate ... divided into sub-groups according to their HBV status: HBV negatives, patients with resolutive HBV infection, HBV/HCV co-infected with overt HBV infection (HBsAg positives) and HBV/HCV co-infected with...
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báo cáo khoa học:" General and disease-specific quality of life in patients with chronic suppurative otitis media a prospective study" pot
... ear and/ or mastoid with irreversible mucosal damage or infection lasting more than months This definition covers adequately the clinical course and findings in our patients from a clinical point ... carried out in accordance with the Declaration of Helsinki as amended in 2004 Patients gave their informed written consent before starting data collection Patients were included in the study ... of life questionings were conducted at all three TM Clinical examination included general ENT examination, microscopy of the ears including Valsalva test and tuning fork test In addition, the...
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Báo cáo y học: "Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease" doc
... atherosclerotic risk factors in MCTD patients In our study population, we investigated the traditional risk factors, in association with clinical symptoms and autoantibodies, in MCTD patients with and without ... Oy, Helsinki, Finland) The concentrations of samples were determined using a standard curve obtained from the optical densities of standards with known concentration Endothelial cell markers Thrombomodulin ... J: Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk J Hypertens 2002, 20:159-169 51 Hashimoto M, Eto M, Akishita M, Kozaki K, Ako J, Iijima K, Kim S, Toba K, ...
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Báo cáo y học: "A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease" ppt
... results in clinical enzymology Clin Biochem 1998, 31:489-494 Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M and Albrecht JK Peg-Interferon ... tests combine five components (α2-macroglobulin, haptoglobin, apolipoprotein A1, γ-glutamyl transpeptidase (GGT), and total bilirubin) for FibroTest and same plus alanine aminotransferase (ALT) ... assess the inter-laboratory variability of FibroTest and ActiTest, including their six serum liver components, in patients with chronic liver disease, and to identify factors associated with that...
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Báo cáo y học: "Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C" doc
... 26 27 markers and biopsy in patients with chronic hepatitis C Clin Chem 2004, 50:1344-1355 Gebo KA, Herlong HF, Torbenson MS, Jenckes MW, Chander G, Ghanem KG, El-Kamary SS, Sulkowski M, Bass ... histological lesions with biochemical markers in patients with chronic hepatitis B J Hepatol 2003, 39:222-230 Murawaki Y, Ikuta Y, Okamoto K, Koda M, Kawasaki H: Diagnostic value of serum markers of connective ... biopsy and METAVIR staging and grading performed Of these patients, 453 were from our center [11,14], including 130 patients coinfected with HCV and HIV [14] Eight hundred and seventy (870) patients...
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Báo cáo y học: "Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American survey" doc
... together with interdisciplinary and international differences in transfusion preferences, should be taken into consideration in the planning of future studies This will help maximize clinician buy -in ... monitoring in SAH patients report targeting higher Hb concentrations, especially in patients with DCI (mean Hb with multimodal monitoring, 8.82 g/dL (95% CI, 8.55 to 0.10); mean Hb without monitoring, ... targeted individuals who work at academic institutions with neurocritical care fellowships and/ or neurosurgery residency training programs, since these clinicians are the most likely to participate in...
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Mortality in patients with chronic and cleared hepatitis Cviral infection: A nationwide cohort study
... liver cancer was rather infrequent (28 events vs event for patients with chronic vs cleared HCV-infection, corresponding to an 8-year risk of 1.4% in patients with chronic HCVinfection and of ... residual confounding The fact that patients with chronic HCV-infection were at increased risk of unnatural deaths (and to some extent death due to infections) indicates certain risk-taking behaviour ... ed Lippincott/Williams & Wilkins; 2008 p 213–37 [23] Kleinbaum DG, Klein M Competing risk survival analysis survival analysis A self-learning text 2nd ed New York: Springer Science + Business...
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Báo cáo hóa học: " Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma" potx
... of germline and somatic mutations of this gene in VHL patients and sporadic RCC Today, more than 400 germline mutations have been reported in VHL patients and about 300 somatic mutations in sporadic ... verified independently by reamplifying the corresponding fragment and repeating the sequencing procedure using both forward and reverse primers in the samples fixed in Bouin's solution Regarding the ... asbestos and welding fumes 20 pack-years < 25 of missense mutations is different in the two groups with 68% of missense mutations corresponding to transversion in somatic mutations vs 35% in germline...
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báo cáo hóa học:" Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF" ppt
... venous ulcers as the basis to investigate the cellular basis of impaired healing Various growth factors play a role in coordinating cellular processes involved in wound healing Platelet Derived Growth ... origin within the wound Moreover, these cells appear to maintain a distinct phenotype in culture, suggesting that they can be used as a tool to test potential therapeutic agents Methods Obtaining ... a rinse with Puck's saline with EDTA followed by incubation with Puck's/EDTA/Trypsin An equal volume of growth medium with serum was added, cells were spun down, resuspended and plated in growth...
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báo cáo hóa học:" Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma" pot
... significant increase in PD-1 expressing CD4+ (p = 0.0329 at weeks and p = 0.0281 at weeks) and CD8+ T cells (p = 0.0373 at weeks) in patients with progressive disease compared to stable patients ... effector CD8+ T cells in whole PBMC and found that there was an increase in CD107a, a marker of degranulation and cytotoxic function [16,17] These cells remained elevated in patients with stable ... Merino MJ, Rosenberg SA: Randomized Study of High-Dose and Low-Dose Interleukin-2 in Patients With Metastatic Renal Cancer J Clin Oncol 2003, 21:3127-3132 Rosenberg SA, Yang JC, White DE, Steinberg...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25