... pattern matching, syntactic and semantic analy- sis, and acoustic analysis can be helpful in detect- ing and correcting these repairs. We use pattern matching to determine an initial set of possible ... 10,517 sentences of varying lengths, it pulled out 500 as possibly containing a repair and missed 97 sentences actually containing a repair. Of the 500 that it proposed as containing a repair, ... edits, and also including the original string un- changed. Each of these strings was analyzed by the parser. When the original sequence did not 60 parse, but one of edits resulted in a sequence...
... chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of ... . Interestingly, HMGN3 has been found to be associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin inhuman hepatocellular carcinoma ... concentration of ethanol in HepG2 cells. Moreover, it constitutes a necessary step in the understanding of the molecular mechanisms involved in alcohol-induced effect inhuman hepatocellular carcinoma...
... deletion abolished binding of an U1snRNP molecule in this position and activated a 3¢ss lying 12 nucleotidesupstream of this element. In the last case, binding of hnRNP E1 and U1snRNP to a silencer ... ItalyIntroductionTowards the end of the 1970s, in the beginning of pre-mRNA splicing research [1,2], defining exons and introns was essentially based on observing the finalcomposition of the ... recognition in the normal splicingprocess [55]. First, U1snRNP binding to an intronicsplicing processing element has been found to inhibitpathological pseudoexon inclusion in intron 20 of theATM...
... erythrocytes in the extent of binding with thelectins concanavalin A, Lens culinaris agglutinin(LCA), and Ricinus communis agglutinin (RCA)(Fig. 3), ruled out the blood origin and supported therenal ... butyrylcholinesterase activityassayed in kidney. This proposal is in agreementwith the cytochemical staining of acetylcholinesterase in the capsule of Bowman [41] andof acetylcholines-terase and ... pathological signs of Alzheimer’s disease in the brain in vivo.Neurobiol Aging doi:10.1016/j.neurobiolaging.2010.04.028.26 Vidal CJ (2005) Expression of cholinesterases in brain and non-brain tumours....
... alsocontains a GAL4 gene under the control of the GAL10 pro-moter. The induction of the yeast, by galactose containingmedia, results in overexpression of GAL4, in turn inducingan increase of the ... function of increasing amount of totalproteins in membrane fractions from I7 yeast strain induced at15 °C, and from yeast expressing SSTR2 as a control.J. Minic et al. Expression of olfactory ... for increasing theyield of properly folded recombinant human gammainterferon from inclusion bodies. J Biotechnol 52, 127–133.Expression of olfactory receptors in yeast for screening J. Minic...
... trans-side of the membrane.Moreover system y+L is inhibited byL-leucine in thepresence, but not in the absence of Na+.The small inhibition of L-arginine in ux byL-leucine in the absence of ... defectivetransport of the cationic amino acids lysine, arginine and ornithine at the basolateral membrane of the polar epithelialcells in the intestine and renal tubules. LPI is caused bymutations in the ... required, were incuba-ted for 1 min at 37 °C in a Dubnoff water bath under gentleshaking in the presence of 1 lCiÆmL)1L-[2,3,4-3H]arginine,unlabelledL-arginine and L-leucine when required...
... role in the correct folding,maturation, and targeting of this protein to its finaldestination [30]. To establish further the role of thepropeptide in the processing and maturation of cathep-sin ... cathep-sin E from lysosomal enzymes.Role of the N-glycosylation of cathepsin E in processing and maturationTo determine the role of N-glycosylation in the correctfolding, processing, maturation, and ... maturation, and traffickingmust be of particular importance. In this study, to understand the molecular basis of the processing and intracellular trafficking of cathep-sin E, we constructed a variety of...
... learning and training. It is in tight connection with gaining new set of knowledge, skills and abilities that an employee need for quality performance with the new and more demanding tasks and ... definition and its meaning, it is very important to define the process of career development and its influence on an individual in a company. Career development is represented by a set of correlated ... apprentices. Their main activities are training, mentoring, leading and influencing others and taking care and responsibility for the work of the younger colleagues. In the previous stages, an employee...
... studies carried out in 40% TFE in an H2O mixture [38]. According to studies of CRH binding to single bilayer egg phosphatidylcholinevesicles, the developmentof the intramolecular interactionwith ... 3082–3090.44. Jaravine, V.A., Alexandrescu, A. & Grzesiek, S. (2001) Observa-tion of the closing of individual hydrogen bonds during TFE-induced helix formation in a peptide. Protein Sci. 10, ... main chaintorsion angles in proteins: prediction of NMR coupling cons-tants for native and random coil conformations. J. Mol. Biol. 255,494–506.27. Wu¨thrich, K. (1986) NMR of Proteins and...
... hypoxia may increase tran scription of the HO-1gene through a certain protein factor in RPE cells. Theseresults indicate that RPE cells maintain retinal homeostasisby repressing or inducing the ... outer segments of photo-receptors through i ts large numbers of villi, and is involved in phagocytosis of shed outer segments [1] andin uptake,processing, and transport of retinoids [2]. RPE ... determinant for the hypoxia-mediated induction of HO-1 expression in D407 cells. In addition, hypoxiacoordinately and rapidly induced expression of both HO-1 and Bach1 mRNAs in cultured rat and...
... adenosinetriphosphate (ATP), 4-aminopyridine, aprotinin, 1-chloro-2,4-dinitrobenzene, clotrimazole, creatine kinase, creatinephosphokinase, daunorubicin, dideoxyforskolin, iso-butylmethylxanthine ... addition of half the original packedcell volume of cold solution L and incubated at 37 °Cfor30 min resulting in spontaneous formation of spectrin-actin-free vesicles [28]. After incubation, ... RPMI-1640) in a 5% CO2humi-dified incubator at 37 °C. The L23/R and MOR/R sublineswere maintained in the presence of 0.2 lgÆmL)1 and 0.4 lgÆmL)1doxorubicin, respectively. The cells were keptin...
... kept in view, and that by [Pg 463] carelessness in the drawing two of the rays are crowded out and terminate against the side of a neighboring ray. In copying and recopying by free-hand methods, ... with the use of clay and a capacity in handling it that, with advancing culture, brought all nature within the reach of the potter and made it assist in the processes of variation and development. ... observation of incidental resemblances. This same figure, in use by the Indians of the interior of the continent, is regarded as symbolic of the whirlwind, and it is probable that any symbol-using...
... peakincrease of approximately 53% in the number of CD34expressing cells andand a 90% increase in CD133 cells in circulation. Furthermore, a significant augmentation of cell s possessing hematopoietic ... marrow injury conditions [43], subsequent studieshave expanded this finding to situations of inflammation[44], and peripheral tissue injury [45-47]. Hematopoieticstem cells are being increasingly ... recognized as havingdiverse non-hematopoietic functions including produc-tion of angiogenic cytokines [48], and acting as an“innate” immune cell capable of rapidly differentiatinginto dendritic...