... positioned in the catalytic center [9,10] Owing to the complexity ofthe ribozyme reactions andthe polyanionic nature of RNA, the catalytic chemistry and folding of group I ribozymes (and other large ... whereas binding of a minimum of m Mn2+ ions forms the inactive complex The sizes ofthe active and inactive fractions are the result of competitive metal binding to RNA The values of n and m are estimated ... most of P9.1 is neutral The 5Â strand of P9.0 is protected despite the absence ofthe 3Â strand For the idiosyncratic P7.1 and P7.2 domains, the helices are weakly protected, except for the 3Â...
... 1.2 F andthe Lipschitz constant of T tends to if ε ↓ For more information on thestructureof fixed point sets see 4, and references therein In 1973, Goebel and Kirk introduced the class of uniformly ... 2.2 k then T has a fixed point in C This result generalizes Lifshitz’s Theorem in case of a Hilbert space and shows that the theorem admits certain perturbations in the behavior ofthe norm of successive ... nonexpansive mappings,” in Handbook of Metric Fixed Point Theory, W A Kirk and B Sims, Eds., pp 49–91, Kluwer Academic Publishers, Dordrecht, The Netherlands, 2001 12 Fixed Point Theory and Applications...
... properties, and Page of 12 therefore can potentially modulate the efficiency and/ or specificity ofthe degradosome-mediated RNA decay More significant differences in thecompositionof degradosomes ... PNPase, phosphofructokinase and enolase [13] Further characterization of these complexes and elucidation of their specific roles in mRNA decay in B subtilis and related species can offer many important ... conserved and can be absent in some classes of bacteria [6,7] The availability of new genomic data and discovery of novel RNases in bacteria prompted us to re-assess the phylogenetic conservation of these...
... ID, father, mother, gender, date of birth, country of birth, and occasionally date of death Only Iceland had data since 1955 In other countries, breeding started in 1975 or later and most ofthe ... Ballou and Lacy [6] and is the mean ofthe kinship coefficients between that individual and all candidates, including the individual itself Candidates are defined as reproductive individuals ofthe ... as the 7-gen-tree All the animals ofthe current population can only carry alleles from the 36 founders In the Icelandic Sheepdog, just three ofthe 36 founders contributed more than 80% of the...
... showing the state of being ofthe trees, 24 flowers, grass andthe children or possession ofthe actors, the Giant andthe children The perception, affection and cognition ofthe Giant andthe children ... the ways in which the various groups and phrases in the clause are ordered with the THEME system The THEME system includes Theme and Rheme The Theme is the element which serves as the point of ... system have the clause as entry condition So, they describe the text in the light of its function in thestructureofthe clause The thematic structure is responsible for the organization ofthe clause...
... especially the (the power, the belief, the rights, the word, the free, the back, the chains, the prey, the quest, the cost, the life and so on) The personal reference is also widely used in the text ... the theoretical background relevant to the objectives ofthe study The researcher has illustrated an overview ofthe notions of form and meaning andthe context model in SFL The combination of ... around the globe -the belief that the rights of man come not from the generosity ofthe state but from the hand of God We dare not forget today that we are the heirs of that first revolution Let the...
... courts, and, on the other, secular jurisdictions, including the justice ofthe king, the justice ofthe lords, andthe jurisdiction of municipalitks (cities), of corporations, andof trade.20 The ... that, with the concentration ofthe power of ennoblement in the hands ofthe king, statutory honor, founded on the recognition of peers andof others and affirmed and defended by challenge and prowess, ... forces (and ofthe direct claims ofthe dominantbbut strongly dependent upon the state The second factor is the degree of autonomy both ofthe educational system andofthe scientific field from the...
... to be reconsidered from the perspective of both sustaining timber yields and ecologically sustainable forest management; in the process thestructureandcompositionofthe primary forest may ... genera and 13 families were identified Ofthe overall number of tree species, 21 were present on both the primary and logged forest sites: species of seedlings, 19 species of saplings, 15 species of ... amurensis, F mandshurica, Q mongolica, A pseudo-sieboldianum, A mono and U japonica), which accounted for 63% of all trees and 91% ofthe total basal area (Tables and 3) These percentages reflect the typical...
... called Theme and Rheme The Theme served as the point of departure ofthe message (Halliday 1994:37), which in English coincides with the initial element(s) ofthe clause; andthe Rheme is the remainder ... which is one ofthe typical features of a narrative 3.4.3 The Theme - Rheme Pattern The analysis shows that most ofthe themes in the text belong to topical theme Of 33 clauses and clause complexes ... ofthe text are taken into consideration 1.4 Methods ofthe Study The aim of this paper is to analyze the meanings and structures of a text The result should be useful for language teaching and...
... sources, the third states the phoric status ofthe tie, andthe last presents the chain relation in terms ofthe address of all the preceding members in the chain Tables and summarise the total ... spaceship The planet They There The spaceship The two astronauts The woman It She We It Both of them They All plants and Animals They They Everything The man Nothing Something He I The engines He That ... complexes analysed for theme, 17 have Our analysis shows that most ofthe unmarked theme and have marked themes in the text belong to the plane of theme At the beginning ofthe text, ideational...
... cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal regions ofthe v-KIND KIND2 andthe MAP2 CD were ... proteins of these subregions (Fig S1C) and 1654 Fig Of all members ofthe KIND family of proteins, only KIND2 binds to MAP2 Pull-down assay (PD) ofthe endogenous MAP2 from cerebellar lysates of P21 ... downstream of v-KIND overexpression [12]) enhances the activity of MAP2 to bind to microtubules and promote their assembly [18], and that the inhibition of JNK1 (such as downstream of v-KIND knockdown...
... Mn-reconstituted enzyme and an additional water oxygen, which, together with the OD2 of Asp165, the NE2 of His79 andthe NE2 of His169, formed an equatorial plane (Fig 3B) The metal ion andthe addi˚ tional ... illustrates the superimposition of ApeSOD with the cambialistic SOD from P shermanii The overall structures of these enzymes were similar; the rmsd ofthe 747 Ca atoms was ˚ 0.695 A ApeSOD eluted from the ... ligand, NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions The manga˚ nese was only 0.06 A out ofthe equatorial plane (Table 3) The angles around the...
... pocket structure As shown in Table 2, the hyperfine splitting constants ofthe 15N nucleus ofthe distal NO andofthe 14N nucleus ofthe proximal His ofthe GmHO-1 complex are closer to those ofthe ... analyses ofthe molecular features ofthe heme–GmHO-1 complex andofthe mechanism of heme degradation were performed, andthe results were compared with those for the heme complexes of SynHO-1 and ... The spectrum ofthe extract is shown in Fig 8B, exhibiting peaks at 404, 534, 636 and 684 nm; the latter two differ from the 660 nm band ofthe protein complex (Fig 8A) When the solution of the...
... despite (i) the very similar structural architecture of OYE1 and PETN reductase, and (ii) geometry for the binding of steroid compounds and 2-cyclohexen-1-one [2,19] Thestructureofthe Y186F ... resolved and are bound between the progesterone andthe protein (Fig 7A) In comparison to the oxidized structures, the FMN isoalloxazine ring is less planar, with both the N5 atom andthe C8-C7 ... s, and indicate re-oxidation ofthe flavin andthe formation ofthe hydride-Meisenheimer complex of TNT (C) As for panel B except the spectral changes are recorded over an extended time period and...
... and R14 was much lower compared to that of P mirabilis G1 and S1959 andthe structures of their O-polysaccharides are significantly different [21,27] Therefore, in spite ofthe occurrence ofthe ... O-polysaccharide part of LPS The serological relatedness of P mirabilis G1 and S1959 correlated with the similarity ofthe chemical structures of their O-polysaccharides (Fig 3) Therefore, it is reasonable ... migrating bands of all LPS tested and slow migrating bands of P mirabilis S1959, G1, and O28 LPS, the banding patterns being clearly different (Fig 5B) These findings together showed that the epitope...
... for the determination ofthe structures ofthe conformers ofthe C-domain The dipolar couplings provided long-distance information on the global folding of both conformers Thestructureofthe ... on one side ofthe b-sheet and two on the other side The rmsd ofthe heavy atoms (Ca, C, and N) ofthe protein core, when the NMR structures of both conformers are superimposed on the crystal ... between the signal ofthe HN of Gly337 in the open conformer andthe signal ofthe water protons All of these observations indicate that the loop region ofthe open conformer has a higher degree of...
... network of hydrogen bonds to the carbonyl oxygen of Pro155, the main-chain amide groups of Ile128 and Arg129 Despite these differences in the coordination ofthe residues in the tip, the fold ofthe ... MetRS:tRNAMet and T thermophilus MetRS (apo) structures reveal that the position ofthe KMSKS loop in our structures is the result of a rotation of 90° around the hinges H1 and H2 located at Asn297 and ... a3, and helix a8 connects helix a7 with strand b9 (Fig 1) The active site is positioned at the C-terminal edge ofthe sheet formed by the five parallel b-strands andthe N-terminal ends of the...