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creation of the large and highly functional synthetic repertoire of human vh and v k domain antibodies

Analysis and detection of human motion in time frequency domain

Analysis and detection of human motion in time frequency domain

Cao đẳng - Đại học

... on the bed) 5.11 The mean and one side standard deviation of positive peak 122-124 and negative peak angular rates of gyroscope sensors at position FW, S and RU Both positive and negative peak ... segments of human motion patterns in 12 the acceleration signals 4.20 44 pairs of Pa and Pv for ascending and descending stairs 96 and 66 pairs of Pa and Pv for level walking from 22 subjects and their ... gyroscope Sternum, wrist, thigh, lower leg Back of the waist, the top of the right heel Left and right sides of waist Back of the waist Back of the waist Shank Mathie MJ [42] Lyons GM [43] 2003 2004...
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Báo cáo khoa học: Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor ppt

Báo cáo khoa học: Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor ppt

Báo cáo khoa học

... of functional properties The kinetics of this loss of activity depends on the type of detergent and 2644 V R P Ratnala et al (Eur J Biochem 271) on buffer composition [26] Solubilization of functional ... Table Recovery of protein and functional H1 receptor at several stages during purification Data are given per liter of culture volume and represent averages of three experiments with standard error ... Kd (nM) and pKi values from three independent assays are given in Table Although the variation is somewhat larger for the Sf9 membranes, the Kds of both preparations are very close, and also in...
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the meaning and structure of a narrative a systemic functional analysis

the meaning and structure of a narrative a systemic functional analysis

Khoa học xã hội

... clause complexes 27 have unmarked theme and have marked theme Using a proper noun at the beginning of the text, then the third person participant reveals the development of the story 10 clause ... textual theme (I, III, IV, V, IX, X, XIII, XV, XVII, XVIII) out of marked themes use adverbs of time (that is adjunct) characterizing the chronological order of the story 3.5 The Cohesion of the ... topic of travel The title of the text is Torquay? But I said Turkey! Between two columns of the text, there is a picture of woman, two maps of United Kingdom and Turkey The woman is holding a ticket...
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Tài liệu Báo cáo

Tài liệu Báo cáo " The meaning and structure of a science fiction story: a sysyemic functional analysis " doc

Báo cáo khoa học

... Table The Theme-Rheme Pattern of the Text Clause Textual Interpersonal Theme Topical Theme Theme Markedness of Theme I The spaceship unmarked II the planet unmarked III They unmarked There unmarked ... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative ... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Báo cáo khoa học

... the esterase activities of the R405A and K4 13A mutants were reduced to about half those of the wild type, whereas the K4 13A /K4 14A and K4 14A mutants, like the S132T mutant, lost esterase activity ... mutant exhibited the same level of lipase activity as wild type The lipase activities of the other mutants, R405A, K4 13A/ K4 14A, and K4 14A, were lower Esterase activity measured with the short-chain ... C-terminal domain of apoCII interacts with the interface of the N- and C-terminal domains of LPL and part of the lid surface [32] Because the functional importance of LPL’s C-terminal domain is...
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Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot

Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot

Báo cáo khoa học

... double-strand breaks (DSBs) A single-strand overhang is formed by exonuclease activity and invades the homologous doublestranded region of the other allele These steps of homology search and recombination ... in-frame with the GAL4 DNA-binding domain in the pBKDT7 vector as bait The cDNA library was subsequently cloned into the pGADT7 vector encoding the GAL4 activation domain, and used as prey in the twohybrid ... and S cerevisiae The KER and ED domains are represented by black and grey boxes, respectively (B) Schematic diagram of the truncation mutants of CcCac1L (C) Interaction between CcCac1L and CcLim15...
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Greasy palms - The social and ecological impacts of large-scale oil palm plantation development in Southeast Asia docx

Greasy palms - The social and ecological impacts of large-scale oil palm plantation development in Southeast Asia docx

Lâm nghiệp

... on the companies trading in palm oil in the UK, the Netherlands and Sweden as well as giving a general overview of the trade in oil palm and the growth of the European market A summary of the ... Rabobank, ING and ABN-Amro and forest destruction and poverty in East Kalimantan, Indonesia Report for Friends of the Earth the Netherlands AIDEnvironment and Puti Jaji 53 Wakker, E and J.W van ... repayment of the development loan from the bank.124 However, from another point of view, the KKPA scheme implies that local people must pay for their own land.125 Like NES, the KKPA scheme is one...
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Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx

Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx

Báo cáo khoa học

... and mM)1, respectively; values correspond to the original plot Derived values of Km and Vmax are presented in Table Solid and hatched bars represent the presence of bound 5¢-UMP ex vivo and the ... extrapolation of the linear portion of the Lineweaver–Burk plot using data points from the low substrate concentration Vmax (L) was obtained by subtracting Vmax (H) from Vmax From the values of Km and Vmax ... mm, and 0.37 mm, and 25%, mm, and 0.60 mm, respectively Hence, the ability of the inhibitors to remove the kinetic lag was inversely related to their Ki, and they also showed specificity of such...
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Báo cáo khoa học: The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXa reductase and human biliverdin-IXb reductase potx

Báo cáo khoa học: The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXa reductase and human biliverdin-IXb reductase potx

Báo cáo khoa học

... the biliverdin binding pocket of BVR-A using synthetic biliverdin isomers The substrate specificity of hBVR-A was examined using a range of synthetic biliverdins locked in Fig The structures of ... of the open chain and locked tetrapyrroles The structures shown are 15Z-syn 18EtBV, 15Z-anti 18EtBV, 15E-syn 18EtBV and 15E-anti 18EtBV various conformations These biliverdin derivatives have their ... 4407 Probing the verdin site of BVR-A and -B E M Franklin et al red shift (for the ‘390’ and ‘660’ peaks) on the addition of BSA and this was particularly marked for the 15E-syn 18EtBV isomer (Fig...
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Báo cáo khoa học: Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus – the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress pot

Báo cáo khoa học: Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus – the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress pot

Báo cáo khoa học

... targeted into the specific sites in which the nerve fibers of the PO innervate the anterior ramifications On the other hand, as a neurohormone, PO-CHH may be released from the surface of the PO and into ... in trunks of the PO Cloning and sequencing of PO-CHH cDNA The first PCR of PO cDNA with a combination of a set of primers LF1 and LR1 (Table 1) produced an amplicon of 500 bp On the basis of this ... amplicon of  1.7 kbp The sequencing of the cloned vector of this amplicon as an insert was completed using M13 F and R and a walking primer (PWF1, ATGGGATATGTTCTCAGT), revealing the presence of a...
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DELEGATED MONITORS, LARGE AND SMALL: THE DEVELOPMENT OF GERMANY’S BANKING SYSTEM, 1800-1914 pot

DELEGATED MONITORS, LARGE AND SMALL: THE DEVELOPMENT OF GERMANY’S BANKING SYSTEM, 1800-1914 pot

Ngân hàng - Tín dụng

... first the private banks, then the credit banks, and then the evidence on Gerschenkron’s view of the credit banks 3.1 Private banks The forerunners of the universal banks that emerged in the second ... at the end of the 1860s as the Schaaffhausen, the first of the joint-stock banks The size of individual private banks was less important because of their habits of working together closely Banks ... credit cooperatives for the savings of workers and the middle class.39 The development of deposit-taking profoundly altered the balance sheets of the Deutsche Bank and other credit banks In 1895 short-term...
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Báo cáo khoa học: Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon doc

Báo cáo khoa học: Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon doc

Báo cáo khoa học

... in the catabolism of the interglobular domain of aggrecan in vitro Biochem J 344, 61–68 17 Kuno K, Okada Y, Kawashima H, Nakamura H, Miyasaka M, Ohno H & Matsushima K (2000) ADAMTS-1 cleaves ... In the case of versican, it is likely that CaPPS and heparin inhibit the catabolism of this proteoglycan by suppressing aggrecanase activity as described above and by inhibiting the activity of ... proteolysis during the early phases of connective tissue degradation [18] We have shown that in ligament and tendon, the loss of small proteoglycans from the tissue involves either the loss of intact...
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Báo cáo khoa học: The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto Functional and structural insights through disulfide structure analysis docx

Báo cáo khoa học: The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto Functional and structural insights through disulfide structure analysis docx

Báo cáo khoa học

... cleavage This strategy took advantage of a Lys residue (Lys112) between the EGF-like domain and the CFC domain and a Met residue (Met154) between the last Cys in the CFC domain and the O-linked ... VWFC-like domains Definition of motifs as VWFC-like are based on SWISSPROT annotations and NCBI DART predictions Protein name No of EGF-like domains No of VWFC-like domains No of Cys in VWFC-like domains ... 2A1), and therefore that the CFC domain is sufficient for the interaction of Cripto with ALK4 To verify the role of the CFC domain in ALK4 binding, we analyzed the effects of point mutations in the...
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báo cáo hóa học:

báo cáo hóa học:" Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation" docx

Hóa học - Dầu khí

... with the adenovirus helper plasmid pXX6 [44], a pAAV packaging plasmid expressing the rep and cap genes (pACG2.1 for AAV2, pLT-RC02 for AAV1 and pLTRC03 for AAV5) and the relevant pAAV2 vector ... representative of at least experiments In a second step, we then selected the VSVG-LV pseudotype at MOI of 18 to transduce the pDC cell line, and evaluated the expression of GFP under the control of different ... exposure to VSVGpseudotyped LV, the percentage of E-GFP expressing pDC was 2.6 fold higher when the expression was driven by the EF1 compared to the PGK promoter The average copy number of the vector...
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Báo cáo hóa học:

Báo cáo hóa học: " Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic " ppt

Hóa học - Dầu khí

... determine the interventricular septal thickness (IVS) by measuring in diastole at the level of the left ventricle minor axis [28] The posterior wall thickness (PWT) was also measured, and the left ventricular ... thickness (LVWT) calculated as the sum of IVS and PWT Table summarizes the main characteristics of patients All them fulfilled the next inclusion criteria: they had an interventricular septum (IVS) ... none of the parents were studied to exclude the presence of asymptomatic LVH # IVS: interventricular septum; PWT: posterior wall thickness; LVWT: left ventricular wall thickness; NYHA: New York...
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báo cáo khoa học:

báo cáo khoa học: "Components of prolificacy in hyperprolific Large White sows compared with the Meishan and Large White breeds" ppsx

Báo cáo khoa học

... of the genotype (HLW, LW or MS), the random effect of the jth sow of the ith genotype, jj f S,; the fixed effect of the series of comparison (1, 2, or 4), P the fixed effect of the parity divided ... is the repeatability of litter size (= 0.15), Xt is the average litter size of the sow and Xc the average litter size of the EGAULT , WEN contemporary sows, both corrected for the age of the ... the number of piglets born (dead plus alive) and the ovulation rate The age at puberty of daughters of HLW sows of the first group, born in Nouzilly, and contemporary daughters of LW and MS sows...
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Báo cáo y học:

Báo cáo y học: "Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex" potx

Báo cáo khoa học

... Figureofon the large form on the kinase activity of P-TEFb in Effects of P-TEFb inhibitors on the kinase activity of P-TEFb in vitro and on the large form of P-TEFb in cells In vitro P-TEFb kinase ... between the loss of the large form of P-TEFb in the cell and the reduction of HIV infectivity demonstrates the tight regulation of the kinase activity in cells and the absolute requirement of that ... errors of the mean of the percent of control values (the number of HIV-1 positive cells in the presence of P-TEFb inhibitors /the number of HIV-1 positive cells in untreated wells) Here, we developed...
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Báo cáo y học:

Báo cáo y học: "Assessment of the effects and limitations of the 1998 to 2008 Abbreviated Injury Scale map using a large " pot

Báo cáo khoa học

... changes affected 37 of the NFS codes, 251 of the small (unilateral) codes and 31 of the (small) bilateral codes All but ten of these 319 changes involved a change in the severity of the AIS08 code ... ReadAllsopp and Louise Niggemeyer read and commented on the manuscript, and we thank them for their valuable advice Many thanks to Sue McLellan, Andrew Hannaford and Peter Cameron from the Victorian ... calculation, in 33.0% of study patients and prevented the calculation of any ISS value in 4.9% of patients Palmer and Franklyn Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine...
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Báo cáo y học:

Báo cáo y học: "Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristic" doc

Báo cáo khoa học

... mDCs and moDCs [12] and moDCs and KG-1 cells [13], but no studies have compared the proteomes of all three cell types In this study we compare the proteomes of mDCs, moDCs and KG-1 cells, and then ... R30 Horlock et al Acknowledgements p < 0.04 The authors would like to thank John Keyte, Kevin Bailey and Matt Carlile (School of Biomedical Sciences, University of Nottingham) for their technical ... compared to moDCs and KG-1 cells refereed research Figure Cell culture work-flow Cell culture work-flow Overview of the methods used for isolation/generation of mDCs, moDCs and DC-like KG-1 cells deposited...
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