... result ofthe presence of negatively-charged residues at P2 and P2Â that arenot accommodated within the b2-tryptase active sitebecause ofthe presence of Asp147 and Asp143within the S2 andthe ... data show that the S2Â subsite of CGis highly polar as a result ofthe presence of three posi-tively-charged residues: Arg41, Arg143 and Lys192 [1](Fig. 1). In chymase, the Arg ⁄ Phe substitution ... hampered studies of their enzymatic properties[4,5].CG and chymase genes are located on chromosome14 together with the genes of granzymes B and H [6]. The two proteases are synthesized as a prepro-protein,containing...
... themwell along with playing the easier ones well. So, the slight edgegoes to the combination of playing the easier holes very well, the equivalent of our holes one through six, and adding good ... in shot-making they demand of themselves. They fully un-derstand the need to develop a slight edge over their opponents. 105 89$ $CH7 02-23-04 16:44:51 PS 84Golf andthe Game of LeadershipOur ... on the shotfacing them. When distracted from their focus they do not plungeahead anyway but rather begin again to set their focus and executeonly when they feel right.In what ranks among the...
... including lexical meaning, synonyms, collocational range, words and idioms of which the word denoting the feeling is a constituent. Some suggestions in the teaching and learning of as well as in the ... Journal of Science, Foreign Languages 25 (2009) 165-173 165 Grammatical and semantic featuresof some English words and idioms denoting happiness - the feeling of great pleasure Nguyen Thi ... nine’, ‘on top ofthe world’, ‘over the moon’ and ‘thrilled to bits’). They are dealt with in respect of their grammatical features including the syntactic functions and morphology, and their semantic...
... ADAM 10 shRNA vector The ADAM 10 small interfering RNA (siRNA) sequence(CAGUGUGCAUUCAAGUCAA) was designed using the software siRNA Target Designer (Promega, Madison,WI, USA). The preparation of ... carried out according to the stan-dards of animal care a s outlined in the Guide for the Care and Use of Experimental Animals ofthe MedicalCollege of Shanghai Jiaotong University. The study pro-tocol ... [10] . These findings strongly suggest thatADAM 10 plays an essential role in tumor metastases. The a im of this study was to analyze the relationshipbetween the expression of ADAM 10and the...
... companies and gives evidence of this in the cases of Microsoft, Cisco, and Oracle. Gristak, “Integrated Reporting Enablement,” echoes the importance of XBRL and Web tools and to these he adds the ... L. GristakLeveraging the Internet for Integrated ReportingKyle ArmbresterPart VII: Better Engagement The Business Imperative of Stakeholder EngagementSandy NessingIntegrated Reporting as ... stakeholder—employees and she makes the case for how integrated reporting will result in a better understanding ofthe company’s strategy and thus higher encourage all of you to go to http://www.storyofstuff.com...
... between the cutting forces and tool wear [1,13, 14], andthe feasibility of techniques of pattern recognitionusing the cutting sound for the discrimination ofthe variousstages of edge wear ... 5°,was placed on the three component forces of dynamometer that washeld on the table ofthe NC machine.Turning was performed by the corner ofthe cutting edge along the edge ofthe disk (work ... cutting speed performed compared to the other tools investigated [5]. On the other hand the other toolsinvestigated varied slightly in the parallel force as the cuttingspeed was increased.The...
... ontologies and, 167, 187 G garbage in garbage out (GIGO), 2generalizationdefined, 108 taxonomies, 146getData() method, 116Globus Project Web site, 83goals, change process preparation, 250graphical ... 229Logic Programming Conferences,158Logic Programming Research Projects, 158logical assertions, 8logical errors, 192logical theories, ontologies represented as, 166, 207logic-based languages, ... 30 Guarino, N., and P. Giaretta, 1995. “Ontologies and Knowledge Bases:Towards a Terminological Clarification.” In Towards Very Large KnowledgeBases: Knowledge Building and Knowledge Sharing,...
... sortiesfrom the town, the food stocks, andthe mood ofthe garrison. The tactics of the Daily Mail captured the attention ofthe nation; the newspaperdramatized the situation ofthe town by emphasizing ... the rank of Major-General. As the War in South Africa progressed, the calm, heroic figure ofthe ever vigilant and patient defender of Mafekingbecame the chief centre of interest. The thoroughness ... Republics, interviewing Eng-lish and Dutch South Africans, investigating the growing discontent of the largely British ‘‘Uitlanders’’ in the mining district ofthe Witwater-srand. Hobson was still...
... intermediate signal intensity on T1-weighted images and range from low to high signal inten-sity on T2-weighted images depending on the degree of hydration ofthe tophi [2].Differential diagnoses ... Radio-graphs still remain the imaging examination of choice forgouty arthritis although advanced imaging techniquesmay be used. The appearance of gout in MR imaging isvariable. Joint effusion and ... in the wrist due to gout [6,8,9]. The prevalence of gout in the USA ranges between 0.5–2.8% in men and 0.1–0.6% inwomen [2]. The prevalence rises to 4.4% of men and 1.8% of women over the age of...
... stress (68). If our findings are proven by further studies in-volving a larger number of patients, ultra-low mi-crocurrent therapy might change the concept of management of chronic disease. Conclusively, ... stress and oxidative damage to tissues are com-mon pathology of chronic diseases, and using anti-oxidants, such as the EPRT device used in this ex-periment, might change the concept of management ... wound healing. The purpose ofthe study is to investigate the efficacy of ultra-low microcurrent delivered by the Electro Pressure Regeneration Therapy (EPRT) device (EPRT Technologies-USA, Simi...
... were F1: 5’ GGT TTA AAC TTT ATT CTG ACT GTT CCC, R1: 5’ ACA CAA TTT AGT AAT AGC CAA AGT CAA C, F2: 5’ GTT GTT GTG AAG TAG AAA CTG ATT TCT AA, and R2: 5’ CTG GGG AGT GGG CCA. Genomic DNA was ... infection andthe high risk of gastric atrophy among seropositive healthy controls, and that seropositive individuals with PTPN11 G/ Gand Gab1 G/ A +G/ G were associated with the greatest risk of gastric ... 2007, 4 4genotype frequency and ORs ofthe Gab1 genotypes for gastric cancer among the seropositive subjects. The Gab1 gene was not associated with the risk of gastric cancer among the seropositive...
... Nevertheless, most of language learners have the same obstacle in comparing and contrasting their mother tongue with a foreign language, which prevents them from acquiring a new language easily and effectively.It ... most ofthe tags can be interpreted as … phải không; … đúng thế không? … à? in Vietnamese (Thiêm, 2004). Accordingly, the tag is the biggest difference between the two languages. In English, the ... comparing and contrasting linguistics has been playing a more and more important role to meet the rising demand for language learning to communicate and scientific developments in the direction of...
... crucial part ofthe honor of the British gentleman andofthe British soldier, whether gentleman by rankor not. But by the turn ofthe century women were agitating for the rightto higher education, ... soldiers ofthe charge.Making use of such assumptions, Doyle shifted the focus of the arguments against the concentration camps. Rather than arguing over the morality of leaving women and children ... translation ofthe ‘‘War Hymn of the Boers,’’ ‘‘sung by the Boers in their camps during the Majubacampaign’’ (Majuba was the scene ofthe infamous Boer defeat of the British in the first Boer War of ).⁵...