characteristics of persons for whom therapy is widely accepted
Báo cáo y học: "Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: an interventional study" pps
... = 0.01), for Page of (page number not for citation purposes) Results Baseline characteristics The demographic and clinical - pathological characteristics of the 30 patients selected for antibiotic ... Germany) for professional support in performing the statistical analyses References 10 Conclusions For the period of application the antibiotic therapy appears to control the disease activity of SAPHO ... whereas discontinuation of antibiotic therapy seems to be associated with disease deterioration In what way a permanent administration of antibiotic therapy (beyond months) is a promising treatment...
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Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... therapy is reasonable for cases of cryptogenic ischemic stroke or TIA with positive aPL On the other hand, oral anticoagulation with a target INR of to [4] is reasonable for patients with ischemic ... which therapy is the most effective for secondary prevention of stroke with APS [4, 8, 9, 10] and concerning the relationship be- tween APS and stroke It is generally accepted that aPL is an ... Med Sci 2010, with APS We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with...
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Tài liệu USE OF INTERPRETERS FOR NON-ENGLISH SPEAKING PERSONS pdf
... investigation, dismissal for lack of probable cause, and the evidence and record of proceedings before the Commission shall remain forever confidential Dismissal for facial insufficiency shall be disclosed ... the Georgia Commission on Interpreters for Non-English Speakers: (A) The Georgia Commission on Interpreters for Non-English speakers will consist of: the current Chief Justice of the Georgia Supreme ... Nonpayment of any required renewal fees; or Violation of the Code of Professional Responsibility for Court Interpreters Commentary: The appropriateness of disciplinary action and the degree of discipline...
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Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx
... As for (316Ala)-ERRc, this kind of reconstruction appears much more difficult For the inverse antagonist activity of BPA, the presence of an inverse agonist and its binding to the receptor is ... Research Grants for Research on Risk of Chemical Substances from the Ministry of Health, Labor and Welfare of Japan This work was also supported in part by grants-in-aid from the Ministry of Education, ... of (275Ala)-ERRc should hold H12 for the position in the active conformation It is evident that such an effect of BPA is only partial, presumably because the binding of BPA to (275Ala)-ERRc is...
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Improvement of different vaccine delivery systems for cancer therapy pptx
... clinical results [4] Therefore, selection of an adequate vaccine-delivery system is fundamental in the design of immune strategies for cancer therapy In this review, we discuss the current delivery ... enhancements, the efficacy of Page of 20 such immunotherapeutic strategies is dependent on the identification of an effective method of DNA administration [31] A comparison was performed between three ... targets the epidermis layer of skin as used in mass-scale prophylactic virus vaccination In contrast, Derma Vax™ primarily targets the dermis layer of skin This system is suitable for when high doses...
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Guidelines for the Investigation of Contacts of Persons with Infectious Tuberculosis Recommendations from the National Tuberculosis Controllers Association and CDC pptx
... Human M bovis TB disease has certain distinctive characteristics but in practical terms is indistinguishable from human-variant TB Human pulmonary M bovis TB disease probably is transmissible to ... negating the need for a second test Treatment is also recommended for these contacts if they receive a diagnosis of latent M tuberculosis infection The risk for TB disease is undetermined for contacts ... and Sites of Transmission Comprehensive information regarding an index patient is the foundation of a contact investigation This information includes disease characteristics, onset time of illness,...
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Responsibility of Applicants for Promoting Objectivity in Research for which Public Health Service Funding is Sought and Responsible Prospective Contractors pot
... that the choice of enforcement mechanisms be left to the discretion of each Institution, and that the PHS should not prescribe specific enforcement mechanisms for use in any type of situation We ... parties is an integral part of the scientific research enterprise and affords many important opportunities for forging relationships and collaborations among researchers The provisions in the revised ... Institution must inform each Investigator of its policy on conflicts of interest, of the Investigator’s disclosure responsibilities, and of these regulations This requirement is addressed as a...
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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... domain of HSP70 is essential for the inhibition of H2O2-induced activation of caspases-9 and -3 and apoptosis (A) The effects of HSP70 and its deletion mutant proteins on the activation of caspases-9 ... anti-apoptotic role of HSP70, which comprises a mechanism that involves the inhibition of Smac release from mitochondria, and the suppression of caspase activation Such a mechanism is independent of the interaction ... activation by eliminating inhibition of caspases by inhibitor of apoptosis protein (IAP) and is known to be a new and important regulator of apoptosis in a variety of cancer cells The evidence obtained...
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Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme Biochem ... concentrations of carnitine: mm (for standard comparison with other published data), and a concentration equal to the Km for carnitine of each enzyme (for comparison between mutants) In this article, ... and C-terminal regions of CPT1A [9] In this model, Asp17 does not face the C-terminal fragment A possible explanation for this is that, in the case of CPT1B, the docking of the N-terminal fragment...
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Báo cáo khoa học: The N-terminal cysteine pair of yeast sulfhydryl oxidase Erv1p is essential for in vivo activity and interacts with the primary redox centre doc
... CGC motif Therefore the systematic functional analysis of the six cysteines in yeast Erv1p was the major goal of this paper All three pairs of cysteines in Erv1p are indispensable for in vivo activity ... residues and the exact distance is found between the corresponding cysteines of Erv1p The reason for this exact match is clear from the structure of Erv2p, because the disulfide bridge between ... possible function of this N-terminal CXXC motif in Erv1p is suggested by the discovery of a CGC motif as part of the flexible C-terminal arm in the related Erv2p [11] In one conformation, this arm brings...
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Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... log of the [Ca2+] free (x-axis) is plotted against the log of bound ⁄ free dye {(R ) Rmin) ⁄ (Rmax ) R)} (F2 ⁄ F2 max) (y-axis) This can then be used to calculate Kd of the indicator, which is ... 3E) and is consistent with data published recently in a different oeopshageal cancer cell line [25] DCA-mediated apoptosis is mediated by a PKC-dependent pathway and is p53 independent One of the ... patients had symptoms of gastro-oesophageal reflux disease, 52 patients had no indicators of disease by endoscopy Forty-eight patients had oesophagitis with varying degrees of severity and 60 patients...
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Use of Alternative Fuels in Cement Manufacture: Analysis of Fuel Characteristics and Feasibility for Use in the Chinese Cement Sector pdf
... forest, sparse forest timber forest orchard, special use forest, timber forest, sparse forest orchard, timber forest, special use forest, sparse forest timber stand, sparse forest, firewood forest ... kilns Table II-8 provides a summary of the key characteristics of miscellaneous wastes as alternative fuels for cement manufacturing Table II-8 Characteristics of miscellaneous wastes as alternative ... for conventional fuel are equivalent to the carbon emissions factor of the fuel that is replaced On the basis of the assumptions used in this report for the carbon content of coal4, biomass offsets...
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Báo cáo khoa học: Biosynthesis of D-arabinose in mycobacteria – a novel bacterial pathway with implications for antimycobacterial therapy pdf
... biosynthesis and the mode of action of ethambutol Recent studies have confirmed that decaprenyl-phospho-arabinose is the only donor of the arabinofuranosyl residues for the synthesis of the cell-wall ... (Rv2181), is necessary for the synthesis of lipomannan [114] Inactivation of the Rv2181 orthologue resulted in the lack of lipomannan and the formation of a truncated lipoarabinomannan in M smegmatis, ... structures and mechanism of action of mycobacterial phosphoantigens are still a matter of debate [123] New methods for the analysis of polyisoprenoid glycolipids The application of tandem mass spectrometric...
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Báo cáo khoa học: Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells potx
... target of LPA [56] On the other hand, it has been shown that the PI3Kb isoform was important for the mitogenic activity of LPA in nonhematopoietic cells that not express PI3Kc [57] PI3Kb isoform is ... Fig 5, motility of PAK1 K299R-transfected cells in the presence of LPA was markedly slower than that of vector transfectant, indicating that the activation of PAK1 is necessary for LPA-induced ... required for LPA-induced A2058 cell motility Discussion PAKs play an important role in a variety of cellular functions including cell morphogenesis, motility, survival, angiogenesis and mitosis [42]...
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Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot
... target for therapeutic vaccines to clear an already established tumour They have been therefore evaluated in preclinical studies for prophylaxis or therapy performing the challenge with transformed ... Giorgi (Istituto Superiore di Sanità, ISS, Rome, Italy), and called pQE30-E6/His and pQE30-E7/His After cloning into JM109 bacterial cells, these were used for the production of the RGS His (H6) ... 50, 62 and 83 died for natural reasons before the fifth priming T1-T5, immunisation times for priming; P1-P4, immunisation times for protein boost Radaelli et al Journal of Translational Medicine...
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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... of foot faults in the left and right forelimbs The sum of foot faults (SOFFF) in the forelimbs is defined as the number of faults of right and left forelimbs, whereas the differentiation of forelimb ... foot faults (DOFFF) is the difference between the number of faults for the right and left forelimbs SOFFF and DOFFF were used as an index of motor deficit CSF aspiration 80 μL of CSF were aspirated ... of the differentiation of forelimb and foot faults (DOFFF) derived from ischemic control mice over four weeks compared to the sham-operated normal control rats The DOFFF of the three groups of...
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báo cáo sinh học:" Community-owned resource persons for malaria vector control: enabling factors and challenges in an operational programme in Dar es Salaam, United Republic of Tanzania" ppt
... aim of this study is to generate a better understanding of the role that the CORPs play within this programme, and the operational prerequisites for these to contribute effectively in terms of ... monitoring the performance of individuals in health-related projects [45] These committees typically consist of an average of eleven members Despite their longstanding existence, little is known about ... populations The participation of communities in vector-borne disease control is context-dependent [4,9,17,18] The degree of community involvement is determined by the type of disease targeted, available...
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Báo cáo sinh học: "Review of the 25th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (now the Society for Immunotherapy of Cancer)" potx
... Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees ... NKp30c isoform and IFNg with isoforms NKp30a and NKp30b Clustering of the NKp30 transcriptional profiles could be used to discriminate between responders and non- responders to Gleevec for gastrointestinal ... information on the mechanism of action of novel therapies and will provide quantitative, noninvasive, pharmacodynamic information on tumor metabolism Cancer Immunotherapy Guidelines: A New iSBTc/...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25