certification validation body an organization responsible for carrying out certifi cation validation and for overseeing the day to day operation of an evaluation and certification or validation scheme 23
Guideline for the intravenous to oral switch of antibiotic therapy
... literature for a variety of different indications 1,4 . Therefore in severe infection an oral dose of 600mg qds can be used. Please note that this is an unlicensed dose and therefore responsibility lies ... Introduction IV to oral switch is the prompt conversion of IV antibiotic therapy to oral. Patients may be considered candidates for switching from IV to oral therapy once the patient ... Continue with IV antibiotics Switch to oral therapy (see Box 1), add indication and intended stop date (see stop/review date policy) Check for any interactions/allergies Continue to monitor closely ...
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Exploring the textbook english for life in teaching english speaking to adult beginners = khai thác giáo trình english for life để dạy nói tiếng anh cho người lớn ở trình độ sơ cấp luận văn thạc sĩ giáo dục học
... carried out for more for the purpose of maintaining social relationships rather than for the transmission of facts and information These conversations are a little trickier for learners because they ... to assert their right to question, criticize and generally participate actively On the other hand, they tend to be more disciplined and conform more to teacher demands than younger learners The ... implications for the more detailed design and selection of materials and tests, the planning of individual lessons and the managements of the classroom itself 2.1.1 Contextual factors In their...
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Tài liệu Báo cáo khoa học: The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane ppt
... Transit peptide of Toc75 A J Baldwin and K Inoue Fig The biogenesis of pea Toc75 The precursor, intermediate, and mature forms of Toc75 are indicated as prToc75, iToc75, and mToc75 with the ... single precursor (e.g., for AGA, compare lanes 19 and 20, 23 and 24, 27 and 28, and 31 and 32, respectively) Furthermore, trypsin-sensitivity of imported proteins was also consistent over the time ... 11 12 13 We thank Dr Daniel Potter for his critical reading of the manuscript, and also members of the Inoue laboratory for their helpful discussions The project was supported by the National...
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The NCI Strategic Plan for Leading the Nation To Eliminate the Suffering and Death Due to Cancer pdf
... approaches for analyzing and reporting data > Support the development of standards for evaluating the performance of multiple technology platforms This will include: • Creating dedicated centers and ... infor comprehensive education and training program in mation, go to cancer.gov/prevention/pob cancer prevention and control at the graduate and For information on the full range of postdoctoral ... This level of shared data access will require user-enforced analysis and format standards so the data can be used for correlative studies NCI will: > Support the development of standards for submitting...
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Báo cáo khoa học: Interaction of an 40 kDa protein from regenerating rat liver with the )148 to )124 region of c-jun complexed with RLjunRP coincides with enhanced c-jun expression in proliferating rat liver pdf
... carried out in the presence of ng of radiolabelled Jun-25 and 100 lg (lanes 1, and 5) and 150 lg (lanes 2, and 6) of nuclear extracts Lanes and represent EMSA performed with nRNE-d, lanes and represent ... formation EMSA were performed using ng of labelled Jun-25 and of 10 lg rRNE-d (C) and rRNE-d (D) in the presence of 0.5 and 1.5 mM of actinomycin D (lanes and 3) and methyl green (lanes and 5) B - 0.1 ... in normal and regenerating liver extracts (Fig 4C,D, lanes and in both panels) On the other hand, methyl green did not affect the formation of the complexes (lanes and 5) The insensitivity of...
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UNDERSTANDING FISHERIES MANAGEMENT: A Manual for understanding the Federal Fisheries Management Process, Including Analysis of the 1996 Sustainable Fisheries Act doc
... about the biology of the stock However, good information about the fishery is required In this assessment, the manager only needs to look at the history of landings for the stock and the effort ... possible about the biology of the species in the stock The other is to learn about the fishing activities for the stock Historically, the demand for a stock assessment has usually come after a stock ... states are responsible for inshore waters and offshore waters out to three miles (nine miles off the Florida west coast and off Texas) The NMFS is an agency of the National Oceanographic and Atmospheric...
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Báo cáo khoa học: "Experience with adjuvant chemotherapy for pseudomyxoma peritonei secondary to mucinous adenocarcinoma of the appendix with oxaliplatin/fluorouracil/leucovorin (FOLFOX4)" docx
... treatment of PMP with systemic chemotherapy More clinical experience and further studies are still needed for determination of the benefit of systemic chemotherapy for these patients The authors declare ... section of appendiceal tumor and one of the peritoneal implants confirmed mucinous adenocarcinoma of the appendix (Fig &5) The diagnosis of PMP was confirmed by the final histopathology Instead of the ... that they have no competing interests CFC performed the initial surgery, conceptualized the case report, gathered the data, reviewed the literature and drafted the manuscript CJH performed the...
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Báo cáo y học: "Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics" pdf
... living human cartilage of the elbow and knee during mosaicplasty for osteochondritis dissecans of the elbow: an in vivo study Am J Sports Med 2008, 36 :234 5 -235 3 Page of (page number not for citation ... Research & Therapy Vol 11 No Kuroki et al that the ultrasound information our technique provides will help clinicians to understand degeneration of articular cartilage – even if the information ... Mori K, Hattori K, Habata T, Yamaoka S, Aoki H, Morita Y, Takakura Y, Tomita N, Ikeuchi K: Measurement of the mechanical properties of regenerated articular cartilage using wavelet transformation...
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báo cáo khoa học: " Rational Prescribing in Primary care (RaPP): process evaluation of an intervention to improve prescribing of antihypertensive and cholesterol-lowering drugs" ppsx
... combination of organizational problems and lack of time and engagement is the most viable explanation for the lack of effect." level of use of the decision-aid system Hetlevik and colleagues, in an earlier ... explanations for this More use of qualitative research methods in the course of the trial could have increased our understanding of the trial results Organisational factors are likely important to ... little of the variation in the main outcomes across practices The authors concluded: "There is not a single explanation for the variation in change in practice or for the overall lack of change...
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guide for determining the fire (reapproved 1994) endurance of concrete elements
... exposed to fire The bottom of the beam becomes hotter than the top and tends to expand more than the top This differential heating causes the ends of the beam to tend to lift from their supports, ... the bottom of e the slab If the underside of the slab is exposed to fire, the bottom of the slab will expand more than the top, resulting in a deflection of the slab The tensile strength of the ... supported reinforced concrete slab The rocker and roller supports indicate that the ends of the slab are free to rotate and expansion can occur without resistance The reinforcement consists of...
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Analysis, evaluations and solutions for improving effectiveness of the foreign currency business operation of the Vietnam bank for Agriculture and rural development
... o f the foreign exchange market Foreign exchange market exists and develops to serve the following demands: - Trade and investment demand: the import export companies need foreign currency to ... instrument about rate of exchange or interest rate A t present, some banks as Citibank, ANZ, and Eximbank began perform the consultant products, manage and invest capital for their customers, not ... manners: - To receive deposits by foreign currency from organizations, individuals, and other credit institutions I the forms o f demand and term deposits and others A gribank does discount and rediscount...
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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... strain A-3 and strain JS45 maintain 80% activity up to 50 °C The enzyme from strain JS45 is colorless and does not have an absorbance peak at 300 nm [5] A cofactor is not required for the enzyme ... deaminases [6,8,27] or to any other sequences available in FASTA and BLAST database programs at the DNA Data Bank of Japan Recently, we reported the cloning and sequencing of the gene encoding ... analysis, and the determination of released ammonia The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabolism, including the deamination step The...
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Báo cáo y học: " Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays" pot
... HapMap and Affymetrix and, thus, these SNPs were corrected by hand For the replicate data, high quality chips (operationally defined as having an SNR greater than 4.5 and 2.36 for the 100K and 500K ... made for BRLMM (purple) and CRLMM (orange) The points are further stratified by call type according to the HapMap gold standard The STY and NSP are the array types described in the text Hmz and ... L, Yang JY, Zhang J: Bioconductor: open software development for computational biology and bioinformatics Genome Biol 2004, 5:R80 Bioconductor [http://www.bioconductor.org/] The R Project for...
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An investigation into students’ conversational needs and some suggestions for a speaking syllabus to the 2nd year english bachel
... approach) It is rather the behavioral organization in terms of the purposes for which language is being learnt and the kind of langue performance (in terms of language functions) necessary for such purposes ... to check and uncover the effects of the syllabus, the extent of the achievements of the students In other words, an important function of the evaluation program is to provide information on the ... Number of theory period: 30% Number of practice period: 70% 3.3.2.3 Organization of the syllabus content Course organization, either on the lesson level or on the overall organization of the course...
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DESIGNING AN END OF YEAR ENGLISH OBJECTIVE TEST FOR 1ST YEAR NON MAJOR ENGLISH STUDENTS OF THE ACADEMY OF FINANCE
... before you leave the photocopier B Don’t forget to switch off the photocopier before you leave the office C Don’t forget switch off the photocopier before you leave to the office D Don’t forget ... order to perform this study, I firstly choose the method of analyzing, summarizing, and synthesizing materials and books to form the theoretical background More importantly, I design an end -of- year ... students can be evaluated Tests can be formal or informal, oral or written; and no one form of testing is necessarily better or worse than another Objective tests, however, offer some advantages...
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Organization Design For Startups
... Organization Design for Startups Startups begin in the sandbox As they grow and f eel the need f or more structure, they of ten f ormalize their architecture instead of clarif ying their ... depends on the culture and management If the organization cannot, the best way to manage a more complex system of relationships is to move to the hive, by creating clear lines of authority Managing ... airly inf ormal Fractal designs keep organizations relatively f lat and f ree of artif icial power structures Creating a f latter organization empowers people throughout the organization to make...
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Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
... Endowment, for providing funding for this work We also thank John Holmes and his colleagues at the Friends of the North Fork of the Shenandoah River for their efforts in the deployment and retrieval of ... Corporation U.S Geological Survey, National Water Quality Laboratory Friends of the North Fork of the Shenandoah River Prepared in cooperation with the Friends of the North Fork of the Shenandoah ... location of the two sampling sites on the North Fork of the Shenandoah River, Virginia Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North...
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Tài liệu Báo cáo khoa học: Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis doc
... Shengqing Yu for advice on the pulmonary clearance assay, R Morell for help with DNA sequencing, Yandan Yang for help with Southern blotting, and Lina Zhu and Yili Chen for help in manuscript preparation ... manner identical to that of the parental LOS The LOS band of revertant O35ElpxX also showed a change from brown to black coloration (Fig 4, lanes and 5) Composition and MALDI-TOF MS analysis of ... O35E, and constructed the corresponding isogenic mutants Analysis of physiochemical and biological features of both mutants was performed to study the functions of these genes and the structures of...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... therefore, the step in the catalytic cycle corresponding to the release of inorganic phosphate ([Pi]) is likely to correspond to the restoration of a high-affinity conformation for the transporter, ... efflux pumps is assumed to correspond to the outward-facing conformation The energy produced by the hydrolysis of ATP is harnessed for the resetting of the transporter to the initial high-affinity, ... substrates and modulators of ABCG2 (and the R482G isoform) to stimulate the rate of ATP hydrolysis [21,24,25], albeit to a lesser degree than that commonly encountered with ABCB1 The translocation...
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Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx
... exception of residues 1–11 and 210 230 The loop connecting a9 and b5 (residues 195–200) was flexible and poor density was observed The electron density for the mutant residue and the ligand was ... histidine can act as both a proton donor and an acceptor in enzymatic reactions, and it should therefore theoretically be able to replace glutamate as a base, to some extent However, this is not the ... also true for the nucleoside analogues This must be a consequence of the tryptophan creating steric hindrance for the purines The intention behind the mutation of Y70 to W was to create an enzyme...
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