b— the formation constant k apos f of soluble calcium complexes
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... V Zara et al M ~1000 kDa ~850 kDa 670 kDa ~500 kDa 670 kDa 440 kDa 230 kDa 150 kDa 78 kDa 66 kDa 35 kDa ~35 kDa ~230 kDa ~500 kDa ~35 kDa ~500 kDa ~35 kDa ~230 kDa ~500 kDa cyt c1 cyt b ISP core ... al ~1000 kDa ~850 kDa 670 kDa ~500 kDa ~35 kDa ~230 kDa ~500 kDa ~230 kDa ~500 kDa ~35 kDa BN-PAGE B The subunit Qcr6p is not required for the formation and stabilization of the 500 kDa bc1 sub-complex ... intermediates, and the sequence in which these putative sub -complexes bind to each other during the assembly of the bc1 complex is also unknown Furthermore, as in the case of the biogenesis of other multi-subunit...
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Tài liệu Báo cáo khoa học: The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx
... Thus, the effect of the alteration of the glycone structure in the stability of the ESà complex (DDGà) for the wild-type and mutant Sfbgly was determined using the kcat ⁄ Km for the hydrolysis of ... Nevertheless, details about the role of different residues of the aglycone-binding site in the stabilization of ESà and the interdependence between the binding of aglycone and the positioning of ... not affect the binding of the glycone within the Sfbgly active site This hypothesis was further investigated by determining the influence on the glycone binding of the Sfbgly interactions with the...
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Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx
... part of the S2 site, to the rest of the molecule, and may therefore affect the catalytic activity of the enzyme by reducing the flexibility of the protein Reduced flexibility may prevent effi- Structure ... VPRK is too short One side of the loop is involved in the binding of the P2–P4 residues of a substrate The other side of the loop is close to Arg94 (Lys in PRK), which in SPRK and VPRK are further ... position of the peptide inhibitors, thus forcing the amino acids on the prime side of the binding site into a different conformation Conclusion The structure of a proteinase K- like enzyme of a psy˚...
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Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc
... Control analysis of the las operon B Koebmann et al Fig Modulation of PFK activity and the effects on growth and fluxes (A) Library of strains with modulated PFK activities The PFK activities were ... Jlactate(aPFK) ¼ )0.414 * aPFK + 42.7, Jformate(aPFK) ¼ )0.0806 * aPFK + 1.80: Jacetate(aPFK) ¼ )0.0237 * aPFK + 3:4 1.17, PK: Jl ðaPK Þ ¼ 0:0298 à ð18:7 À aPK Þ Ã ð1 À eÀ7:9ÃaPK Þ þ 1=aPK À0:641 à aPK ... ðÀ0:4Þ for the acetate flux 2295 Control analysis of the las operon B Koebmann et al Fig Construction of a strain with the pyk gene deleted from the las operon Truncated fragments of PFK and LDH...
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Tài liệu The Formation of Christendom, Volume VI pdf
... beginning of his dignity to the See of the Apostle Peter For the newly-elected pontiff acknowledges in his letter that Peter is the chief of the Apostles and the Rock of the Faith: that the keys of the ... greater life: a life of another kind generating also an empire of another sort The raid of Genseric in the year 455 is the first of three hundred years of warfare carried on from the time of the Vandal ... at the beginning of the fifth century was justified by the experience of Theodorich at the beginning of the sixth And, further, we may take the conduct of these two great men as expressing on the...
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Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... differences in the C-terminal part of the enzyme (Fig 2A) where 13 of 44 amino acids are different Therefore, chimeric enzymes with the N-terminal part from the human and the C-terminal part from the murine ... of an XmnI site When stable transformants expressing these chimeric constructs were studied, it was evident that the sequence difference responsible for the lack of association of the human Fig ... were constructed by use of the EcoRV and SacI sites in the cDNA and were then used to transform 293-cells The region responsible for the different degree of association of the human and murine enzyme...
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Đề tài " Numerical characterization of the K¨ahler cone of a compact K¨ahler manifold " doc
... definite forms is one of the connected components of the open set P = {det(α) > 0} of hermitian forms of positive determinant (the other components, of course, are the sets of forms of signature (p, ... investigate the behaviour of the K hler cones Kt of the various a −1 (t), as t runs over S Because of the assumption of local fibres Xt = π triviality of π, the topology of Xt is locally constant, and therefore ... structure and the homology classes of analytic cycles: if X is a compact K hler manifold, the K hler cone K of X is one of the connected components of a a the set P of real (1, 1)-cohomology classes...
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Báo cáo khoa học: Protein aggregation and amyloid fibril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot
... contacts higher than the cut-off) and the size of the region is greater than or equal to the size of the sliding window used Optimum values for the cut-off (threshold) and the sliding-window length ... enter the scoring function as a physical property term Sphysprop consisting of the sum of the products of the amino acid frequency with the normalized property value of the respective amino acid for ... technique First, an expected value is assigned to each residue of the protein, equal to the probability of backbone–backbone hydrogen bond formation observed for this type of residue; then, the obtained...
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Báo cáo khoa học: Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter potx
... reasonable selection of scaling factors The main features of this kinetic model are that k2 > k1 (k2 $ k1 app; k1 $ k2 app), and that back reactions are negligible The faster decline of the intermediate ... value for Kdiss is given GTP showed afnities in the same order of magnitude On the other hand, ADP, the product of the ATPase reaction, bound to CopB-B with approximately half of lig the afnity of ... by the formula ẵEA F1 3ị F ẳ F0 ỵ ẵEt Equilibrium binding of other nucleotides in the presence of mant-ATP For determination of binding constants of non-uorescent nucleotides, a series of...
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Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx
... that these marks occur independently of the recruitment of any lineage-specific transcription factors such as PU.1 Furthermore, they observe the presence of components of the TFIID complex (TAF 10 ... recruitment of factors to the a-globin gene locus during the differentiation of erythroid cells The regulatory elements located upstream of the a-globin genes also appear to initiate the activation of the ... (UF) for helping us with ES cell differentiation We appreciate the effort of Dr Keiji Tanimoto (Tsukuba, Japan) for critically reading the manuscript This work was supported by grants from the...
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Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc
... in Fig 3, the biosynthesis of androstadienol in humans (A) and pigs (B) does not require prior formation of 17a-OH-preg and DHEA The lack of androstadienol synthesis in the presence of lM of ketoconazole ... in HEK293 cells in culture, we compared the formation of Ó FEBS 2003 Biosynthesis of 5,16-androstadien-3b-ol by human P450c17 (Eur J Biochem 270) 1353 Fig Role of cyt b5 in the formation of androstadienol ... DHEA formation However, we observe a more profound effect on the synthesis of androstadienol More precisely, an increase of androstadienol formation was observed at a cyt b5/P450c17 ratio of : (Fig...
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Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
... the expression of the gene coding for this receptor, Northern blot experiments were performed The results revealed that the expression level of the glucanbinding protein at the beginning of the ... strong increase in the expression of SDFIBI occurs Likewise, a strong expression pattern was determined for the SDEGFI-PREC gene (Fig 6) The level of expression of the housekeeping gene, tubulin, ... a threefold higher level of the EGF exists Fig Level of epidermal growth factor (EGF) in tissue after treatment with curdlan (A) Antibodies against the EGF precursor were prepared from the recombinant...
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Báo cáo khoa học: Mercury(II) binding to metallothioneins Variables governing the formation and structural features of the mammalian Hg-MT species pptx
... stereochemistry and degree of folding of the species formed Thus, to understand the reaction pathways followed by Zn-MT and apo-MT species in the presence of Hg(II), the effect of each of the previous variables ... Ó FEBS 2004 Fig Role of the chloride anion in the degree of folding of Hg-MT species observed by comparing the CD spectra of the Hg11-MT species obtained in the titration of Zn7-MT with either ... the formation of Hg7-bMT Comparison of the three sets of CD data indicates that the degree of chirality of the Hg-bMT species is generally independent of t However, the chirality of the species...
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Báo cáo khoa học: Detection and characterization of a novel extracellular fungal enzyme that catalyzes the specific and hydrolytic cleavage of lignin guaiacylglycerol b-aryl ether linkages pdf
... oxygen affects the formation of the quinonemethide Then, water attacks the Ca position in the quinonemethide and the b-aryl ether linkage is cleaved Another water molecule then attacks the Ca position ... S paucimobilis SYK-6 [13] b-Etherase is a member of the glutathione-S-transferase superfamily [14] It catalyzes the reductive cleavage of the b-aryl ether linkage of GOU aO (Fig 7, structure ... Analysis of the products of the reaction revealed the presence of guaiacylglycerol (GG) and 4MU (data not shown) Localization of enzymatic activity To confirm the localization of the b-aryl ether...
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Physics of magnetism and magnetic materials k buschow, f de boer
... to The lifting of the (2J + 1)-fold degeneracy of the ground-state manifold by the magnetic field is illustrated in Fig 3.1.1 for the case Important features of this level scheme are that the ... to use only the first term of the series expansion of for small values of y From this follows, keeping only the first term, SECTION 3.2 THE CURIE LAW The magnetic susceptibility is defined as magnetic ... Weiss field We will first investigate the effect of the presence of the Weiss field on the magnetic behavior of a ferromagnetic material above In this case, the magnetic moments are no longer ferromagnetically...
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Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... mislocalization of the WD ATPase in the endoplasmic reticulum [24] This trafficking defect as well the difficulty of producing enough of mutant protein has complicated the attempts to study the roles of the ... exhibiting a marked reduction in the formation of the ADP-sensitive phosphointermediate The mutants of the HP motif (H475Q and P476L) show ATP-driven phosphorylation levels of 32% and 26% of the wild-type, ... C,H,S) The location of the domains and sequence motifs is based on the crystal structure of Ca-ATPase [4], the membrane topology of which is likely to differ from that of ZntA associate with the...
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Báo cáo Y học: The human b-globin locus control region A center of attraction potx
... bound by members of the family of kruppel-like zinc finger (KLF) proteins [16] ¨ Potential candidates for proteins acting through this element are EKLF, FKLF, FKLF-2, and BKLF [17] The CCAAT box ... also hold the LCR in an inactive configuration Heme-mediated inhibition of Bach1/maf binding at later stages of differentiation would allow the binding of other members of the NF-E2 family of proteins ... transitions, the first of which is the formation of DNase I HS sites in the LCR [55] Does the formation of HS sites at this early stage in differentiation require replication? In other words, the proteins...
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The formation of the plural noun in English and Vietnamese equivalents
... are often found preceded by a noun phrase that serves to make them countable A piece of furniture Many pieces of furniture 22 A bit of information Numerous bits of information A bottle of wine ... form the plural Singular form Belief Plural form beliefs 39 Chief chiefs Roof Roofs Cliff Cliffs Muff muffs 2.1.1.2.2 Singular countable noun with ending -y For nouns ending in consonant + y form ... preposition The subject of a verb Eg: A plane is taking off (Khuê,1999: 27) The direct object of a verb Eg: Frank sent an urgent telex from Cairo this morning The indirect object of a verb 15 Eg: Frank...
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tem study on the formation process of tio2 nanotubes
... Theoretically, the distance of the layers of the wall should be γ OH − +2 γ Ti + =4×0.12 nm+2×0.075 nm=0.63 nm8 Owing to the repulsive force between OH- groups, the distance of the layers of the wall ... images (After reaction with alkali for 12 min) a) Swelling side (pointed by arrow); b) Fragments peeling off from granular TiO2 TEM Study on the Formation Process of TiO2 Nanotubes Figure Figure ... and EDS Figure 1a and 1b show the TEM images of the raw TiO2 and the sample treated with alkali for respectively Obviously, they are different in size, the latter is bigger than the former, which...
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Báo cáo khoa học: The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of b-glucosidase docx
... (Fig 6), and support the long half-life of the enzyme The inability to detect IFG in the brain of L444P GCase mice is most probably a result of the dose of IFG tartrate administered (20 mgÆkg)1Æday)1) ... 2010 FEBS R Khanna et al ages further evaluation of this molecule for the treatment of neuronopathic forms of Gaucher disease The administration of IFG to L444P GCase mice for up to 24 weeks reduced ... stress, which, in turn, could affect the organ weights and plasma marker levels of these animals Whether the effects of IFG on the organ weights and plasma markers of inflammation in L444P GCase...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25