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anatomy and function of the heart valves

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Báo cáo khoa học

... between the Leu residues from v-KIND and MAP2 contributes to the interaction between the two proteins.In conclusion, the present study has clarified the structural and functional importance of the ... localized to the N-terminal region, and theirspecific functional domains are located in the C-termi-nal region. The C-lobe of protein kinases mediates the interaction with activators, substrates and ... KIND1, Spire-2 KIND and PTPN13 KIND(Fig. 6A). The amino acid sequences of the coreregions of mouse, human and Gallus v-KIND shared65.6% homology, and 17 identical and four function- ally similar...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Báo cáo khoa học

... proHP8Xa and the catalytic domain of active HP8 are marked with arrowheads. The size and position of molecular weight stan-dards are indicated on the left. (B) The catalytic activity of activated ... comparison of the genomic and cDNAsequences. Analysis of the amino acid sequences deducedfrom the cDNA, including prediction of signal peptide and glycosylation sites, was carried out in the expasy ... B. mori Spaătzle-1 [23]. We performed3Â-RACE and 5Â-RACE to obtain the missing ends of the cDNA, and then used primers encompassing the start and stop codons, with larval fat body cDNA astemplate,...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf

Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf

Báo cáo khoa học

... region of the 1H,15N-HSQC spectrum of the C-terminal domain of human eRF1 illustrating the presence of two conformational states of the protein.Fig. S2. Plot of the number and distribution of the NOEs ... sizes of the relative populations and possibly the rate of conformerinterconversion are sensitive to the environment of the domain.For the great majority of the residues in the minido-main, the ... for the determination of the structures of the conformers of the C-domain. The dipolar couplings provided long-distance informa-tion on the global folding of both conformers. The structure of the...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx

Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx

Điện - Điện tử

... W,issimply the sum ofthe body mass of all individuals. For organisms ofsimilar size, itcan be estimated by taking the product of the population, N,andthebodymass,M. Similarly, the store of each ... obvious.We asked the author(s) of each paper to examine the importance and role of body size in the systems in which they work. Essentially the book builds from the level of the individual and a consideration ... is Professor of Ecology in the School of Biological and Chemical Sciences at Queen Mary, University of London.DAVID G. RAFFAELLI is Professor of Environmental Science at the University of York.RONNI...
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Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf

Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf

Báo cáo khoa học

... interruption of the geometry of the recognition helix for either Antp or the TTF-1HD, the anomalous amide exchange pattern and the NOE connectivity data of the C-terminal portion of helix III ... consistent with the NOE trend of the correspondingadjacent residues and hence does not conflict with the global interpretation of the data. With the exclusion of the N-terminal octapeptidyl and C-terminal ... Lorentzian model of J(x) calculated over avery wide range of correlation times, s. Most of the experimental points accumulate rather close to the upper intercept of the theoretical curve and the fitting(solid)...
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Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

Tài liệu Live Red in support of the Heart and Stroke Foundation of Manitoba pdf

Tổ chức sự kiện

... lesser of 10% of the value of the gift and $75, then the value of the advantage is considered to be zero. For example, if the price to attend the benefit dinner is $200 and the value of the dinner ... dinner, the value of the dinner is $40 and the value of a gift bag received is $45, then the total advantage is $85 or 85% of the ticket price and therefore cannot be receipted. However if the ... for the purchase of an auction item?Yes, but only if the bid amount exceeds the value of the item by 20%. The amount of the receipt is equal to the difference between the bid amount and the...
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Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

Báo cáo khoa học

... as the insert region is located between the pair of primers(Fig. 2A). The lengths of the PCR products of Noxo1b and Noxo1c were 225 and 240 bp, respectively. Todelineate the difference in the ... analyzer and expressed as the foldincrease relative to that of the band forNoxo1c in the absence of PMA.R. Takeya et al. Expression and function of Noxo1cFEBS Journal 273 (2006) 36633677 ê 2006 The ... the SH3 domain of Noxo1 participates inregulation of Nox3, the role of the PX domain in Nox3activity remains unknown.In the process of cloning of human Noxo1, somespliced transcripts of the...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Báo cáo khoa học

... studies. The highselectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen-sional structures and the relative ease of synthesis, makesthem ... domain of each subunit contri-butes to the formation of the hydrophilic pore. ACh binding proteinhas structural and functional homology to the extracellular ligandbinding domain of the nAChR, and ... native and heterologously expressed nAChRs The examples presented above clearly demonstrate the usefulness of a-conotoxins in the determination of the structure and function of native nAChRs, and...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Báo cáo khoa học

... resemble teardrops [32].Further examination of the structure and sequence of sbwAFP and TmAFP reveal other similarities (Fig. 8 C). The panel shows the similarity of the TXT face again, a ndalso ... determine the handedness of the proteins, ormay prevent the unfolding of the protein at cold temper-atures. The b-helix as an AFP structural motif? The sbwAFP and TmAFP structures represent the firstAFPs ... Fig. 4 B. The overlap emphasizes the similarity of the b-strand along the TXT face of TmAFP.Even though the number o f residues i s approximately h alf, the d isulphide core of TmAFP and resultant...
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Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt

Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt

Kĩ thuật Viễn thông

... understanding of the heart as a muscular pump and of the interaction between the heart and the vasculature. The concepts of contractility, preload and afterload are paramount to this understanding ... understanding and will be the focus and repeating theme throughout the text. A sound understanding of cardiac physiology begins with basic understanding of cardiac anatomy and of the physiology of muscular ... contraction and instantaneous atrial volume). The pressure of the point at the bottom right corner of the loop is the pressure in the ventricle at the end of the cardiac cycle and is called the end-diastolic...
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Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx

Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx

Báo cáo khoa học

... Additionally,because the demand of the chloroplast is ‘sensed’inside the organelle, the IEM is closest to the origin of the signal, and thus regulation at the Tic complexcould be one of the fastest ... transmembrane-helices at the extreme N-terminus, which anchor the protein in the membrane. The position and function of the longC-terminal tail on the other hand remains a matter of controversy [10,11,13–15]. ... description of recent advances in the understanding of the chan-nel-, motor- and regulatory components of the Ticcomplex. For reference, some of the available know-ledge, including the proposed function...
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Báo cáo khoa học: Purification, microsequencing and cloning of spinach ATP-dependent phosphofructokinase link sequence and function for the plant enzyme pdf

Báo cáo khoa học: Purification, microsequencing and cloning of spinach ATP-dependent phosphofructokinase link sequence and function for the plant enzyme pdf

Báo cáo khoa học

... to the stimulation of the cytosolic isoen-zyme observed in spinach and other plants [27]. Thesedata suggest that the purified protein was the chloro-plast isoenzyme, although the level of inhibition ... 204,302–309.26 Garland WJ & Dennis DT (1980) Plastid and cytosolicphosphofructokinase from developing endosperm of Ricinus communis. II. Comparison of the kinetic and regulatory properties of the isoenzymes. ... & Muăller M (1998) The pyro-phosphate-dependent phosphofructokinase of the pro-tist, Trichomonas vaginalis and the evolutionaryrelationships of protist phosphofructokinases. J MolEvol...
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Báo cáo khóa học: Selective release and function of one of the two FMN groups in the cytoplasmic NAD + -reducing [NiFe]-hydrogenase from Ralstonia eutropha pptx

Báo cáo khóa học: Selective release and function of one of the two FMN groups in the cytoplasmic NAD + -reducing [NiFe]-hydrogenase from Ralstonia eutropha pptx

Báo cáo khoa học

... holds two of the Fe-S clusters in the small subunit of the D. gigas enzyme is missing in HoxY of the SH, suggesting anexposure of part of the hydrophobic surface of the HoxH subunit. Itwas therefore ... shows the effect of the FMN concentrationon the reconstitution of the activity of the reduced SH.Addition of about 80 nMFMN induced half maximalactivity.Table 1. The effect of air on the reductive ... standardhydrogenases, the SH is not sensitive towards oxygen and carbon monoxide and shows no redox changes of the Ni-Fe site. The Fe-S clusters in the HoxFUY subunits and the flavin in the HoxF subunit...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học

... comparison of the effects of roughandsmoothLPSsofE. coli, both in the presence and absence of EDTA (Fig. 1). The rate of oxidation wasincreased in the presence of the LPSs of both the smooth and rough ... measure of the rate of oxidation of oxyHb.RESULTS The effect of pH on the auto-oxidation of cross-linked Hbwas studied. The rate of decrease of the concentration of oxyHb increased as the pH ... of oxidation in the presence of EDTA.A comparison of rough and smooth LPSs of E. coli and S. minnesota in the presence of EDTA revealed that both in the presence and absence of EDTA, the oxidation of cross-linked...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx

Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx

Báo cáo khoa học

... all stages of the reaction. The best explanation for these results maybe that the reaction of SDTG at the binding site of onesubunit changes the conformation of the o ther subunit,thereby completely ... manipulations and analysis were performed using the PYMOLsoftware [41].Results and DiscussionSynthesis of SDTGSDTG was synthesized by nucleophile displacement of achlorine atom of the 1,3,5-sym ... oneMet121 prevents the reaction of the Met121 of the s econdsubunit. The biphasic kinetics observed may be explainedby assuming that the two subunits, o r at least the conformation of the Met121 side...
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