... particularly motivated by the vaccine for seasonal in uenza (flu) epidemic and luxury goods In Chapter 2, we study thein uenza (flu) vaccine supply chain inthe USA Thein uenza vaccine inthe USA is produced ... equal to the available supply The second component is due to the inefficiency inthe allocation of vaccines, i.e., if the vaccine was allocated to individuals in decreasing order of their infection ... and inthe demand-side intervention increase while the gap between them first increases then decreases Consequently, the value of demandside intervention first increases then decreases inthe yield...
... ‘blunt’, trauma , ‘gastrointestinal’ and ‘injuries’ found three articles using the Medline and Embase databases A retrospective study of 203 children who suffered intra-abdominal trauma following ... pseudocyst The pseudocyst can be seen pushing the stomach and duodenum anteriorly at the time of surgery The cm transverse duodenal laceration is pointed out by the tip of the forceps (indicated by the ... those which not reduce in size during a sixweek observation period [9,10] This is the first reported case of a duodenal laceration following minor blunt abdominal traumainthepresence of a large...
... the need to provide an airway within minutes have lead to the introduction of the approach through the cricothyroid membrane, the most superficial portion of theairwayinthe midsection of the ... larynx positioned inthe thoracic inlet rather than the neck proper, resulting in intrathoracic placement of the trachea virtually in its entire length These challenges of individual anatomy ... an airway, and with it the loss of adequate gas exchange, results in irreversible brain damage within minutes There is a narrow window for technical error due to the delicate nature of the airway...
... traumatic brain injury, part 1: Guidelines for themanagement of severe traumatic brain injury J Neurotrauma 2000;17:451-533 Piek J Decompressive surgery inthe treatment of traumatic brain injury ... thread), and then the superficial vessels supporting the portion of brain run inthe artificial “vascular tunnel” between the brain tissue and dura Finally, the dura was closed as in augmentation ... so that each incision in one row was adjacent to an intact dural bridge inthe rows on either side The same course was then performed, but in a direction vertical to the initial incision This...
... a-synuclein incubated alone (A), inthepresence of 100 lM MPTP (B), inthepresence of 200 lM MPTP (C), inthepresence of 100 lM MPP+ (D), inthepresence of 200 lM MPP+ (E), inthepresence ... solid line), inthepresence of 100 lM neurotoxin ( , dotted line), inthepresence of 200 lM neurotoxin ( , dotted line) and inthepresence of neurotoxin and 50 lM dopamine (h, dashed line) • 1692 ... a-synuclein incubated alone, and inthepresence of 100 lm MPTP and 200 lm MPTP, respectively Notably, inthepresence of the neurotoxin, there was a delay inthe lag time for fibrillation The lag...
... equations of the first kind (the “hedging equations”) have solutions Furthermore, the integral operators appearing in these equations (the “hedging operators”) turn out to be adjoint of the martingale ... Writing (3) in integrated form, we obtain t f (t, s) = f (0, s)+ α(u, s)du+ t σ(u, s)dWu + t δ(u, x, s)µ(du, dx) E Inserting this expression into (9), splitting the integrals and changing the ... the (γ, ϕ) -process, as usual, comes from the martingale rep˜ resentation theorem, with γ i as the integrand corresponding to W i and i ϕ(i) as the integrand corresponding to the N -process The...
... undetectable inthepresence of Mn2+ The solvent-exposed C-terminus of VpUcyt probably pointed away from the surface of the micelle The three amide cross-peaks originating from the hydrophobic ... chains of the Ser53 and Ser57 inthe interhelical linker, forming a highly conserved phosphorylation motif, are visualized in ball-and-stick format In contrast to the well-defined helices and the ... loop, there was considerable fuzziness inthe interhelical linker region Likewise, the relative position of helix and the tight loop was poorly defined according to the relatively high rmsd of the...
... acids inthe plasmin molecule, the amidolytic activity of two truncated plasmin variants was examined (Fig 8) Miniplasmin (des-kringle 1-4 plasmin) contains the kringle and the catalytic domain ... of plasmin activity inthe course of the assay inthepresence of stearate (Table 1) The good fit of Model III progress curves to the experimental data supports the concept that inthepresence ... A Fig Kinetic parameters of plasmin inthepresence of fatty acids The values of kp and Km were determined from the amidolytic assay of plasmin activity, according to Model I, inthe presence...
... obtained inthepresence of heparin (closed circles) This indicates that thepresence of heparin did not in uence the k306 inthe partially active FVa intermediate In a second experiment, the ... tubes containing either heparin or buffer Monitoring of FVa activity in these two tubes was continued for another 25 min, during which time the loss of FVa activity inthe absence of heparin (open ... of the heparin-binding site in these three crystallized protein–heparin complexes were given as starting point for the docking search [30] At least one conformation of the simulated protein–peptide...
... BuChE, as indicated In each panel, the solid circles indicate the measured kcat values, the solid squares indicate the measured bkcat values, and the lines are the result of fitting the measured ... BuChE, as indicated In each panel, the solid circles indicate the measured kcat values, the solid squares indicate the measured bkcat values, and the lines are the result of fitting the measured ... between the serine and the leaving group; and then between the attacking water and the serine In its role as a proton shuttle, the catalytic histidine formally accepts a proton from a donor and then...
... committing the government to the introduction of resource accounting and budgeting In Australia the main driver for change was the introduction of Accruals-based Outcome and Output Budgeting In Canada, ... Integrating evaluation within the broader performance management system • Using performance information for external performance reporting to stakeholders and for internal management learning ... monitoring systems Using performance information: Using information from performance monitoring and evaluation sources for internal management learning and decision-making, and for external reporting...
... determined the F structure containing the truncated region of the C-terminal domain; however, we failed to determine the structure of the intact glutaminase because the crystals exhibited heavy twinning ... 428 aa; nine aa in total) were located near the interface of the physiological dimer The Cterminal domain may contain structural features involved in protein–protein interactions to form the physiological ... differences inthe interactions across the domain interface All the residues involved here seem to be unrelated to the Trisbinding site residues (including Arg223 and Ser227), either directly or indirectly...
... and DGD° values inthepresence of these osmolytes are given in Table However, DGD° values of RNase-A inthepresence of alanine, serine, lysine, b-alanine, taurine and dimethylglycine have not ... references therein] The binding model claims that an increase inthe osmolyte-induced stability arises from the preferential hydration (or exclusion of the osmolyte) leading to a shift inthe denaturation ... glycine, l-alanine, l-proline, l-lysine, l-serine, b-alanine, taurine, sarcosine, dimethylglycine, glycine betaine, trimethylamine N-oxide, and cytidine 2¢-3¢ cyclic monophosphate were also obtained...
... there were some farmers who could preserve Aloe (22.7%) by chopping the leaves and storing them in a container Others would store the raw leaves in a safe cool place, but the Aloe could remain ... could be used to treat human beings (80.9%) Almost all the Aloe used inthe study area was collected from the wild (94.7%), with the remaining 5.3% being grown by the farmers to save as flower ... The finding that the herbs were reported to produce acceptable results is in agreement with previous findings that A vera treatment was accompanied by quick recovery from ailments.9 The finding...
... reflect the state of the recycling industry in 2005 Changing industry trends have had a significant impact on these estimates since then and will continue to alter the distribution inthe near ... needing management, we examined how much material has been recycled in recent years by the electronics recycling industry We then calculated the amount potentially being disposed of by finding the ... the basis for estimating the number and weight of products within the scope of this report requiring EOL management at some point inthe future Historic sales data from industry sources was the...
... Water Management Water Managementinthe Netherlands | | Rijkswaterstaat Preface Introduction The development of water managementinthe Netherlands The history of the formation of the Netherlands ... absorbing it inthe summer The water level inthe lake influences the seepage water and groundwater flows In short, everything is interconnected Interconnectedness This interconnectedness is the ... regional system drains into the main system, while the regional system can be fed by the main system in periods of drought In low-lying parts of the Netherlands, the water that enters the system has...
... agitation and heating of the process fluid • Claim delivers up to 50% energy savings and reduced processing time (30 mins from 60 mins) for the intensive wort boiling stage of the brewing process PDX® ... is introduced into a special annular "conditioning" chamber that is wrapped around the core of the PDX Reactor unit • It is injected into the process fluid at supersonic conditions generating ... Continuous Wort Boiling • wort is in- line heated up to its boiling temperature • Added hop is also homogenized An adapted agitator is assuring a sufficient mixing for the trub formation Among other...
... assist them in interpreting and putting into practice the advice provided inthe recent ACIAR and FAO manuals based on their fishery The workshop will centre on the principles within the ACIAR ... on: their intimate involvement inthe sea cucumber fishery in their country; their position inthe agency to influence management change; their profile to contribute strongly to the workshop ... the number of them in Papua New Guinea They are the resource owners, so limiting fishers would infringe on their rights to the resource Regulating the number of buyers and licensing them should...
... Recurring maintenance In order to maintain the quality of the Weidmoos bird habitat, regular recurring maintenance measures have to be undertaken, in addition to the re-waterlogging The following ... birds from northern breeding grounds fly south inthe winter, whilst others overwinter at their breeding grounds A number of individuals regularly spend the winter at the Weidmoos The ornithologist ... one of the indefatigable volunteers involved inthe execution of maintenance measures Photo: R Kaiser Many people help to maintain the Weidmoos The regular ripping-up of the ground creates the vegetationfree...
... need the anisotropy during the growth process for the nanoparticles In our experiments, thepresence of the salts is also an important factor influencing the crystallization process and the growth ... of the WO3 nanowires With the addition of different inorganic salts, the compositions and the corresponding properties of the solution are different inthe hydrothermal conditions The changes in ... the final products were demonstrated in Fig 1a–c On the basis of the SEM check, the proportion of the nanowire morphology was estimated to be about 100% (Fig 1a) As shown inthe SEM images, the...