351 tfeu the principle of loyalty and the future role of the member states´ bilateral investment treaties
International Humanitarian Law and Human Rights Law Towards a New Merger in International Law
... Examples are the Magna Carta of 1215 the U.K Bill of Rights of 1688, the French Declaration of the Rights of Man and of the Citizens of 1789, the U.S Bill of Rights of 1791 The demand for human ... of August 22, 1864 for the Amelioration of the Condition of the Wounded in Armies in the Field was drafted.9 This convention was followed by a range of treaties, each of them the product of the ... has been through the application of rules of the law of war The development of rules on the conduct of hostilities, means and methods of warfare (Hague Law),37 and the protection of individuals...
- 609
- 1,039
- 0
The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... rescue, and transposon mutagenesis, create signiÞcant changes in the genetic makeup of plants and animals due to the random recombination and sorting of thousands of genes As a result of intervention ... commercially introduced in the U.S in 1996 and have been rapidly adopted by farmers It has been estimated that 24% of the corn and almost 70% of the soybeans and cotton grown in the U.S in 2001 were ... detecting the presence of GM ingredients Unfortunately, standardized methods not currently exist for most of the GM ingredients on the market today Two types of tests are used for the detection of GM...
- 6
- 498
- 0
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... for the cell cycle-dependent expression The sequence upstream of the CHR does not match any of the published CDEs However, alteration of a putative CDE, which is more distant from the CHR than the ... located upstream of the CDE-like site [46] These observations and the fact that activation does not rely on CCAAT-boxes, NF-Y or Sp1 proteins, leave open the question of whether the BUB1B promoter ... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA Conservation of spacing is required for optimal promoter activity because changing the...
- 17
- 876
- 0
Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... activation of the glutaminase reaction and CTP synthesis was compared (Fig 5) In the absence of GTP, the rate of glutamine hydrolysis was signicantly higher than the rate of CTP synthesis so that the ... locks the enzyme in the active form for CTP synthesis and thereby stimulates the kcat of the reaction Since GTP actually will activate the uncoupled glutaminase reaction the structure of the monomer ... (Figs 4C and 5) One might have expected that if the role of GTP was solely to increase the rate of glutamine hydrolysis, there would have been no effect of adding GTP when the rate of CTP synthesis...
- 8
- 698
- 0
Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx
... third cluster of CHCs is part of the inter-domain segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation of the third cluster ... the 55¢–67¢ and 258¢–264¢ loops would be present On the other hand, PLP binding to the apoenzyme is expected to stabilize the structure of the loops and, indirectly, the association between the ... phosphate moiety of PLP Therefore, the capability of the third cluster of CHCs to confer stability to the polypeptide loops of the active site is presumably important in all members of the fold type...
- 12
- 578
- 0
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... establish the importance of GSK3 in the acute regulation of glucose transport in terms of its regulatory control of GS in muscle and fat cells we have investigated the effects of Li and the anilinomaleimide, ... elements implicated in the regulation of GSK3 and GS To further understand the effects of Li and SB-415286 on cell signalling events we assessed their effects and that of insulin on p70S6K, PKB, ... and myotubes with antibodies against GSK3a and b Fig 1B shows that whilst preadipocytes express both GSK3 isoforms, the abundance of the b isoform declines by 85%, whereas that of the a isoform...
- 10
- 804
- 0
Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx
... net synthesis of glycogen or the combination of both The rates of total glycogen synthesis and 13C label incorporation into glycogen (Fig 5) suggest that the overall rate of glycogen synthesis ... enrichments of glycogen C1 and C6, and the net glycogen synthesis rate were measured, Eqns (1), (2) and (3) can be ð6Þ Initially, the enrichment of glycogen is low ([13G1yc6]/ [Glyc] < 1) and the temporal ... Sagittal (left) and transverse (right) images of the liver of a control mouse acquired using the FLASH sequence (TR ¼ 10 ms, TE ¼ ms) The rectangles indicate the location of the volume of interest,...
- 9
- 465
- 0
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... Tyr These mutations may influence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme for PAA and derivatives thereof, while maintaining the ... formation of semisynthetic b-lactam antibiotics The X-ray structure of the complex of PA with PAA shows that the acyl binding site of PA is made up of several hydrophobic residues from the a and the ... located ˚ at the bottom of the binding pocket at A from the nucleophilic serine, does influence the rate of formation of the acyl-enzyme, as judged by the effect of the mutations on the activity,...
- 8
- 561
- 0
The role of floating-rate bank loans in institutional portfolios pdf
... tax, and investment advice from a licensed professional These views are subject to change at any time based upon market or other conditions and are current as of the date at the beginning of the ... for the other asset classes listed on the chart Indexes are unmanaged and cannot be invested in directly Data is historical and is not indicative of future results Russell Investments // Role of ... on the riskiness of a loan) The credit spread reflects market price movements The default rate is the default rate of a bank loan portfolio (historically, 2%–3%), and the recovery rate is the...
- 9
- 333
- 0
Perceptions About Network Security: Survey of IT & IT security practitioners in the U.S. pptx
... Charts and on the following page show perceptions about the security of the IT infrastructure and the level of confidence in the ability to prevent network security breaches We believe the fact ... about the cost is consistent with two other studies Ponemon Institute conducts annually: the Cost of a Data Breach and the Cost of Cyber Crime According to the findings, the average cost of one ... percent of respondents not know the source of the network security breaches Of the 60 percent who say they know the source of all (11 percent) most (16 percent) or some of the attacks (33 percent),...
- 25
- 349
- 0
FUTURE OF THE NUCLEAR SECURITY ENVIRONMENT IN 2015 pptx
... 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute ... with the principle of equal security, keeping in mind both the nuclear and non-nuclear aspects of the picture, the placement of elements of forward base deployment, and the presence or absence of ... important to understand the reasons for the behavior of some states.43 So, on the one hand, there is a need to make the NPT regime more stringent, and on the other hand, the existing international...
- 324
- 504
- 0
Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx
... Interestingly, the sum of ATP and UTP was two-fold higher than that of CTP and GTP, and the ratio of dATP and dTTP to dCTP and dGTP was also : [16,17] This fact is in accordance with the genome composition ... volume of 20 lL The reaction was initiated by the addition the enzyme (100 ngÆreaction)1 for the determination of NTP synthesis rates and 0.5–1 ngÆreaction)1 for the determination of NDP synthesis ... Table The effect of ATP concentration on the equilibrium concentration of labelled adenine nucleotides The initial concentration of [3H]AMP was 100 lM and the concentration of MgCl2 was 10 mM The...
- 8
- 349
- 0
Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf
... column and successively washed twice in the same order and with the same volumes of the four mixtures of solvents then used for the elution After seeding the sample, the elution was made in the ... On the other hand, the absence of the inhibitor in free follicle cultures, may be due to the lack of cellular proliferation, absent in this type of culture These facts support the hypothesis that ... until the appearance of brown spots, typical of carbohydrates The silica of the second plate, with no detection reagent, was scraped at the position where the brown spots had appeared on the first...
- 8
- 440
- 0
báo cáo hóa học: " The role of cumulative physical work load in symptomatic knee osteoarthritis – a case-control study in Germany" potx
... participated in the study design and and helped to draft the manuscript, NA participated in the design of the study and performed the re-assessment of all X-rays, GE coordinated the study and helped ... osteoarthritis and both the total number of squatting and the duration of kneeling work D'Souza et al [20] examine the relationship between the daily amount of kneeling and knee osteoarthritis in the subset ... Power of the study Calculation of the power of the study was based on an expected prevalence of kneeling of 9% among the male population according to Seidler et al [8] To detect an odds ratio of...
- 8
- 518
- 0
báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx
... reported yet Kim and colleagues accepted the cut off SUVmax value as 2.5 in their study at which the role of PET/CT was investigated, and they found out the Page of sensitivity of the technique ... [17] The guideline also recommends PET for evaluation of therapy response and to make the decision of continuing the ongoing therapy or stopping and redirecting the patient to other salvage therapies ... important limitation that the number of patients is small especially in the first group, the number of studies in the literature investigating the role of PET in the diagnosis of distant metastasis...
- 5
- 390
- 0
Báo cáo y học: "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models" pps
... axis of communication between the innate and adaptive parts of the immune system that might be an interesting target for the immunotherapy of inflammatory autoimmune diseases [26,27] Role of IL-17 ... (IL-17) in bone resorption The interrelationship of IL-17 with receptor activator of NF-κB ligand (RANKL), IL-1, tumor necrosis factor (TNF) and the modulatory role of IL-4 and osteoprotegerin (OPG) ... Furthermore, IL-17 has a function in prolongation of the arthritis process and can be considered an important target for the treatment of destructive arthritis The discovery of IL-17 family members...
- 9
- 294
- 0
Báo cáo y học: "The role of tumor necrosis factor-alpha in systemic lupus erythematosus" pdf
... of the patients under infliximab therapy, depending on the test system By means of the Crithidia luciliae immunofluorescence test (CLIFT), Charles and colleagues [20] found anti-dsDNA in 22 of ... subacute cutaneous lupus erythematosus (SCLE) lesions [52] Given the role of TNF as a strong mediator of inflammation, the high levels of serum TNF in active SLE, and the overexpression in renal ... still limited, Page of (page number not for citation purposes) there are a minimum of 28 cases reported at least in abstract form [56-61] and most of these are on the use of the chimeric monoclonal...
- 8
- 464
- 0
Báo cáo y học: "Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints" potx
... participated in the study design and drafted the manuscript SO and KXK were involved in the acquisition of the data MW participated in the analysis and interpretation of data FFH and BS conceived the study, ... We further investigated the effect of DMOG on the expression of two HIF-regulated genes, PGK1 and SOX9, using quantitative RT-PCR Furthermore, the influences on the expression of Col1A2 and Col2A1 ... articular cartilage tissue and degeneration of the menisci The cartilage of the lateral compartment and the patellofemoral joint was affected with fibrillation and fissuring There were also no significant...
- 12
- 393
- 0
Báo cáo y học: " Role of taurine on acid secretion in the rat stomach" ppsx
... ganglia and fibers distributed all over the muscle layers of the rat stomach (Figure 2) CSAD- and taurineimmunoreactive cells were observed along the length of the mucosal gland (Figure 1C and Figure ... found the presence of taurine-containing cells and taurine-induced acid secretion in the stomach In the body of the stomach, taurine-immunoreactive cells were observed along the length of the mucosal ... designed and supervised by RHL and LHT Experiments were performed by KHH and CCC Analysis of the data was performed by KHH, CCC and JDH LHT drafted the manuscript and all authors read and approved the...
- 10
- 490
- 1
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25