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Báo cáo y học: " Evolution of the uniquely adaptable lentiviral envelope in a natural reservoir host" potx

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Báo cáo y học: " Evolution of the uniquely adaptable lentiviral envelope in a natural reservoir host" potx

... [71],SIVsm appears to be highly glycosylated in naturallyinfected SMs. Presumably, continually evolving antibodyresponses in these natural hosts maintain a highly glyco-sylated surface protein, albeit ... fragment spanning the V1–V2 hypervariable region of envelope. The gag regionwas amplified using shortgagF1 (5'TTAAGTCCAAGAA-CATTAAATGC-3') and shortgagR (5'GTAGAACCTGTCTA-CATAGCT-3') ... stud-ies of naturally SIV-infected SMs and African green mon-keys (AGMs) [56-63] by demonstrating that viruses foundwithin a single animal can vary by greater than 35% at the aa level. The ranges of...
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Báo cáo y học: "Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors" pdf

... 7:94http://www.retrovirology.com/content/7/1/94Page 2 of 7Figure 3 Analysis of synonymous and non-synonymous mutation in the plasma virus and proviral compartments. Shown are p-distancevalues for plasma (A) and proviral (B) sequences as ... Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G,Kwan R, McLaughlin M, Stallings S, Rehm C, O’Shea MA, Mican J,Packard BZ, Komoriya A, Palmer S, Wiegand AP, Maldarelli F, Coffin JM,Mellors ... sequenceanalysis and participated in study design. RFS participated in study designand helped to draft the manuscript JNB conceived of the study, andparticipated in its design and coordination and...
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Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx

... – was originally estimated using the least squaremeans obtained from an analysis of covariance with study andbaseline values as covariates.Table 1Patient demographics and baseline disease ... OA pain, patient's global assessment of disease activity, and functional impairment. We present dataon patient satisfaction according to PASS during and at the end of the study period and ... disease activityPatient's global assessment of disease activity. (a) Percentage of patients considering their state as satisfactory according to Patient Acceptable Symptom State (PASS) at weeks...
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Báo cáo y học: " Evolution of subtype C HIV-1 Env in a slowly progressing Zambian infant" potx

... neutralization of the 6-month viral isolate by baseline infant plasma(i00) was 68% compared to 90% by baseline maternalplasma (m00) at the same dilution (1:20), indicating thatonly a subset of ... Zam-bian mother and infant pair (MIP 1157) for more than 6years. The mother and child are anti-retroviral naïve andremain clinically asymptomatic. Infant 1157 was infected in utero since HIV-1 ... contem-poraneous plasma neutralization of the 12-month infantviral isolate indicated a very low level of activity (Figure6B). Only 15% of the input virus was neutralized by the infant 12-month plasma...
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Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf

Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf

... (MS)Glyoxylate  H2O  acetyl-CoA ! malate  CoASHMS (EC 4.1.3.2) catalyzes the transfer of the acetyl moeity of acetyl-CoA to glyoxylate to yieldL-malate. The glyoxy-somal enzyme has been isolated ... sequencediversity [70].Isocitrate lyase (ICL)Isocitrate ! succinate  glyoxylateICL (EC 4.1.3.1) catalyzes the cleavage of isocitrate intosuccinate and glyoxylate. The reactions catalyzed by ICLand malate ... complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining t he individual phylogenies of the 21 s ubunits comprising the 14 enzymes of thesepathways as they occur in eukaryotes,...
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Báo cáo y học: " Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41" pdf

... involved in the study. JPM partici-pated in the study design and coordination. BB supervised the study, and participated in its design and coordination.All authors read and approved the final manuscript.AcknowledgmentsWe ... electroporation. The cultureswere inspected regularly for the emergence of revertantviruses, using CA-p24 ELISA and/or the appearance of syncytia as indicators of virus replication. At regular inter-vals, ... nearSOS evolution pathwaysFigure 4SOS evolution pathways. The SOS-escape routes are summarized by focusing on four key amino-acid positions. The two SOS cysteines are marked in yellow, and loss of...
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Báo cáo y học: "Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition" pdf

... Kurokawa K, Yamashita A, Nakata M, Tomiyasu Y, Oka-hashi N, Kawabata S, Yamazaki K, Shiba T, Yasunaga T, et al.:Genome sequence of an M3 strain of Streptococcus pyogenesreveals a large-scale genomic ... [9]. Although S. agalactiae normally behaves as a commensal organism that colonizes the genital or gastroin-testinal tract of healthy adults, it can cause life threateninginvasive infection in ... respectively. The arrow locates the concatenated tree. (a) (b) (c) (a) (b) (c)S. agalactiae recombination heatmapsFigure 6S. agalactiae recombination heatmaps. The layout is the same as Figure...
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Báo cáo y học: "Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity" ppsx

... individuals included in the cohortwas not included in the analysis. Of the available samples,genotyping was attempted in 1,600 and was successful in 1,589 in the current study. Of all the controls ... dis-crimination assay as described previously [9]. Duplicate sam-ples and negative controls were included across the plates toensure accuracy of genotyping. In addition, for all the assays,genotyping ... in allele frequency of this SNP compared with the others. Hence,genotyping of all four SNPs was unnecessary and, in the remaining samples, only the putative disease causal polymor-phism was...
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Báo cáo y học: " Fractures of the bilateral distal radius and scaphoid: a case report" doc

... dorsal plating [5-7].ConclusionHigh-energy traumas to the hand and wrist can result in ipsilateral and even bilateral fractures of the radius andscaphoid, and initiation of an early rehabilitation ... injuries.Case presentation: A patient with bilateral comminuted, displaced distal fractures of the radiusand bilateral fractures of the scaphoid was treated via internal fixation of the scaphoid fractureswith ... screws and internal fixation of the distal radius fractures with locked volar plating.Conclusion: Rigid internal fixation of distal radius and scaphoid fractures is mandatory to startearly active...
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Báo cáo y học: "Expression of the α7 nicotinic acetylcholine receptor in human lung cells" pdf

... muscle-type nAChRs [17]. In addition, we have foundthat NNK activates the Raf-1/MAP kinase pathway result-ing in phosphorylation of c-myc [10]. This activation wasinhibited by alpha-bungarotoxin. ... chronic treatment of pregnant monkeyswith nicotine caused a pronounced upregulation of the α7 nAChR in the lungs of the newborns [24]. Togetherthese data indicate that the α7 nAChR may play an impor-tant ... tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmo-nary neuroendocrine cells. J Cancer Res Clin Oncol...
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