Báo cáo y học: " Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study" potx
Báo cáo y học: " Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study" potx
... al.: Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study. Respiratory Research 201112:37.Miniati et al. ... lackingtransmembrane and cytosolic domains, acts as a decoy receptor for R AGE ligands in the extracellular compart-ment, and is believed to afford protection againstinflammation and cell injury ... 12:37http://respiratory-research.com/content/12/1/37Page 5 of 9RESEARCH Open Access Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control...
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Báo cáo y học: "levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control" docx
... joint disease; RA = rheumatoid arthritis; RAGE = receptor for advanced glycation end products; sRAGE = soluble receptor for advanced glycation end products. Arthritis Research & Therapy Vol ... of soluble receptor for advanced glycation end products (soluble RAGE) in blood and synovial fluid (SF) of rheumatoid arthritis (RA) patients and in patients with degenerative/traumatic joint ... et al.R822resulting in an activation of several intracellular pathwaysincluding NF-κB [14].sRAGE, a truncated form of the receptor, binds ligands with affinity equal to that of cellular RAGE....
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Báo cáo y học: "erum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis" doc
... 2Research articleSerum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and ... Kurita-Nakamura Y, MatsuiT, Yoshida T, Sato A, Imaizumi T: Elevation of soluble form of receptor for advanced glycation end products (sRAGE) in dia-betic subjects with coronary artery disease. ... receptor for advanced glycation end products (RAGE) lig-ands is not sufficient to induce inflammatory signals: lack ofactivity of endotoxin-free albumin-derived advanced glycation end products. Diabetologia...
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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
... by binding DAMPs and otherligands and inhibiting leukocyte recruitment in a varietyof acute and chronic inflammatory conditions [4]. BothesRAGE and sRAGE act as decoy receptors for the ligandHMGB1 ... local cytokines.Sepsis HMGB1 propagates inflammatory responses and is a significant RAGE ligand in the setting of sepsis and acute inflammation. HMGB1 is an apparent autocrine/paracrine regulator ... results in chronic inflammation and in many instances is the setting in which epithelial malignancies arise. RAGE and its isoforms sit in a pivotal role, regulating metabolism, inflammation, and...
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Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx
... β-pleated sheetfibrils of amyloid and advanced glycation end products (AGEs)[15]. AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, diabetes and ... Silman AJ:Baseline levels of C-reactive protein and prediction of deathfrom cardiovascular disease in patients with inflammatory pol-yarthritis: a ten-year followup study of a primary care-basedinception ... examined at only a single time point, which occurred at variable times after com-mencing a variety of antirheumatic drugs rather than atbaseline. In RA, proinflammatory ligands of the RAGE, includingS10 0A1 2...
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Báo cáo y học: ":The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1" ppsx
... cartilage and bone in the affected joints. Synovial hyperplasia is a hallmark pathology of RA, and fibroblast-like synovio-cytes (FLS) play a critical role in RA pathogenesis byproducing pro-inflammatory ... Bucciarelli LG, Wendt T, Sakaguchi T, Lalla E, Qu W, Lu Y, Lee L,Stern DM, Naka Y, Ramasamy R, Yan SD, Yan SF, D’Agati V, Schmidt AM:Blockade of receptor for advanced glycation endproducts: a ... pro-inflammatoryloop and sustain the inflammatory response. In ourstudy, IL-17 was a strong inducer of RAGE in RA-FLS.IL-17 exerts an important role in inflam mato ry diseasesboth directly and...
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Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc
... of a charged and linear lysine for a uncharged and branched asparagineat position 103 result in a drastic change in the chemicalenvironment in the proximity of the mutation. This hasmainly ... mutant would beexpected to have favorable interactions with the mutantasparagines side chain, thereby compensating for resistancecaused by stabilization of the mutant enzyme due to a hydrogen-bond ... and xdlDA-TAMAN – programs for r eformatting, a nalysis and manipulationof biomacromolecular electron-density maps and reflection datasets. Acta Crystallogr. D52, 826–828.27. Kleywegt, G.J....
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... ligands mRNA expression increased in the aging thymus. The CCR5 ligands, CCL4 and CCL5, increase in the thymic parenchyma as revealed by the age-associated increases in the staining of thymocytes ... perivascular space in the septa and capsule. Ad-ditionally, these cells were visualized in the subcap-sulary region of aged thymi and inside the thymic aged parenchyma in contact with thymocytes ... which act in a paracrine, autocrine and/ or endocrine manner (4-5). The accumulation of adipocytic cells and an increased percentage of fat in several ectopic regions of the body with aging have...
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Báo cáo y học: "Women convicted for violent offenses: Adverse childhood experiences, low level of education and poor mental health" docx
... create a model for female offending.Many of the researchers point out that the origins of maleoffending cannot simply be transferred to female offend-ing without necessary investigation as ... childhoodphysical, psychological and sexual abuse and that conductproblems were evident early on (lack of graduation). In adulthood, there appears to be a tendency toward poormental health (psychiatric ... Corresponding author AbstractBackground: In past years, the female offender population has grown, leading to an increasedinterest in the characteristics of female offenders. The aim of this study was...
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Báo cáo y học: " Clinical implications for Vascular Endothelial Growth Factor in the lung: friend or foe?" ppt
... predisposing injury and in theabsence of heart failure [7]. The hallmarks of ALI areincreased capillary permeability, interstitial and alveolaredema, influx of circulating inflammatory cells, and for- mation ... resistant to the damage and leak induced byVEGF or inflammation [14]. Existing data suggest thatVEGF and angiopoietins act in a very complementary and coordinated fashion [13]. Finally, the ephrins, ... ReferenceProvocation of intratracheal VEGF overexpression in miceDose-dependent increase in extravascular lung water intra-alveolar edema, and increased pulmonary capillary permeability.[19]Administration...
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