... matrix metalloproteinase;NF-jB, nuclear factor-jB; nSMase, neutral sphingomyelinase; PC, phosphatidylcholine; pH e, extracellular pH; PKCf, protein kinase Cf;PLC, phospholipase C; PLD, phospholipase ... activitycould be induced by PC-derived diacylglycerol (DAG)through PC-PLC but not by phosphatidylinositol 4,5-biphosphate-derived DAG through PLD followed byphosphatidate phosphatase. Because ... release of Ca2+from theendoplasmic reticulum by inositol 1,4,5-triphosphate(IP3 ), a product of phospholipase C (PLC). Voltagedependent Ca2+channels (VDCC) have been classifiedinto low...