Báo cáo khoa học: " Dispersal and flight behaviour of lps sexdentatus (Coleoptera: Scolytidae) in pine forest" pptx

... Scots pine beetle lps sexdentatus Boern (Coleoptera: Scolytidae). J Appl Entomol 104, 190-204Koponen M (1980) Distribution of lps amitinus(Eichoff) (Coleoptera: Scolytidae) in ... orientation of the flight direction when the speed of the windrose > 3 m/s. This value is more importantOriginal article Dispersal and flight behaviour of lps sexdentatus (Coleoptera: ... use of the pheromone trapping system for the control and prognosis of lps sexdentatus. lps sexdentatus / bark beetle / pine / mark recapture / dispersal / flight behaviour...

Báo cáo khoa học: Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase pdf

... a-heli-cal LID domain, situated in the C-terminal moiety, and the NMP-binding (NMPbind) domain move in aninduced-ﬁt mechanism, closing upon binding of thephosphate donor and acceptor nucleotides, ... structures of CMP and UMP, and interactions between the cyto-sine moiety of nucleotide and various sidechains of wild-type CMP kinase. (Upper)Chemical differences between CMP and UMP are indicated in ... time intervals,aliquots were withdrawn and diluted in buffer containing10 lgÆmL)1 of soybean trypsin inhibitor. The ﬁrst-orderrate constant of inactivation of CMP kinase by TPCK-tryp-sin was...

Báo cáo khoa học: "Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats" ppsx

... histopathological lesions in the seminiferous tubules. There were thickening and multiple layering of the tubular endothelium, and theformation of many multinucleated giant cells in seminiferous tubules. ... Thickening and multiple layering of the tubular endothelium (arrow), and the formation of many multinucleated giantcells (arrow heads) in seminiferous tubules. H & E stain, ×50.106 Hye-Jin ... thatacrylamide and/ or glycidamide binding to spermatidprotamines causes dominant lethality of gonadal cells and morphological abnormalities of sperms. One of thehistopathological lesions observed in the...

báo cáo khoa học: "Expression and prognostic significance of cancer-testis antigens (CTA) in intrahepatic cholagiocarcinoma" ppt

... any extent of immunostaining in se ctions and furthergraded into four groups: + : < 5% of tumor cells stained;++ : 5-25% of tumor cells stained; +++ : > 25-50% of tumor cells stained; ++++ ... only.Cases were included according to the followinginclusion criteria: having archived formalin-fixed, paraf-fin-embedded specimens available; having completeclinicopathological and follow ed-up ... 2011References1. Patel T: Increasing incidence and mortality of primary intrahepaticcholangiocarcinoma in the United States. Hepatology 2001, 33:1353-1357.2. Hsing AW, Gao YT, Han TQ, Rashid...

Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

... studies of the structure and binding sites of enzymes. 8. Inhibitor binding toribonucleases. J Mol Biol 45, 491–511.33 Ui N (1971) Isoelectric points and conformation of proteins. I. Effect of urea ... similarity in theKmvalues is attributable to the uracil moiety binding in the same fashion [38], which could trigger the initialbinding of both substrates. In UpG, the binding of theguanine moiety ... analogs containingsulfonate and sulfonamide internucleoside linkages.Patent 5561225, 1–12.30 Fisher BM, Ha J-H & Raines RT (1998) Coulombicforces in protein–RNA interactions: binding and cleav-age...

Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc

... The transfer of phosphate can lead to phosphorylation of inosine,guanosine and a number of their analogues [2]. There-fore, in addition to being involved in regulation of purine intracellular ... sites 1 and 2 and involved in bind-ing of adenylic nucleotides and BPG.Our results partially conﬁrm the molecular model-ling, suggesting that effector site 1 is the binding sitefor Ap4A and ... crystallized in the presence of adeno-sine indicates that this nucleoside binds to this site,even though only the amino acid residues involved in the binding of the purine base were identiﬁed,...

Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx

... activity of PRTFDC1towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, of the activity of HPRT, the role of the PRTFDC1 in purine metabolism remainsunclear and it is uncertain ... and hypoxanthine. (B) HPRT and hypoxanthine. (C) PRTFDC1 and guanine. (D) HPRT and guanine.Table 2. Km and Vmaxvalues for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 ... However, a tight binding of N7 of the purine base and Asp137 was observed in HPRT in complex with ImmGP, indicating a role in transitionstate stabilization during catalysis [17].A series of mutations...

Tài liệu Báo cáo khoa học: Isolation and molecular characterization of a novel D-hydantoinase from Jannaschia sp. CCS1 docx

... accessing hydantoinases involved screening and iso-lating naturally occurring enzymes possessing hydan-toin-hydrolyzing activity from microbes, and usingthem to produce optically pure amino acids ... DNA of the corresponding organisms. The PCR fragments of the coding regions of HYDs were inserted in- frameinto pET28a, resulting in HYDs that were His-taggedat the N-terminus. Expression of ... quantities of protein uti-lizing the principle of protein-dye binding. AnalBiochem 72, 248–254.42 Runser SM & Meyer PC (1993) Puriﬁcation and bio-chemical-characterization of the hydantoin hydrolyzingenzyme...

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: electron transfer through the nitric oxide synthase ﬂavoprotein domain pdf

... activation in place of theflavoprotein, and then redox cycles within NOS; and (d) heme–NO binding is an intrinsic feature of cataly-sis that constrains the rate of heme reduction by theflavoprotein ... Role of the C-terminaltyrosine of ferredoxin–nicotinamide adenine dinucleo-tide phosphate reductase in the electron transferprocesses with its protein partners ferredoxin and flavodoxin. Biochemistry ... Ca2+-binding protein calmodulin(CaM) to enable their participation in biologicalsignaling cascades. By contrast, iNOS binds CaMregardless of the Ca2+concentration and can remaincontinuously...

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: probes of hydrogen tunnelling pptx

... Comparison of rates and kinetic isotope effects using PEG-modifiedvariants and glycoforms of glucose oxidase: therelationship of modification of the protein envelopeto C–H activation and tunneling. ... the role of dynamics in interprotein [65–68] and intraprotein [69] ET reactions and protein rearrange-ment after carbon monoxide dissociation from myoglo-bin [64]. In general, the rates of ET ... barrier and profoundly in uence the reaction rate [4,6–12]. In recent years, wehave investigated H-transfer reactions in a number of enzymes, primarily quinoprotein [4,13,14] and flavo-protein [8,15–20]...

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