... after the addition of glutamine, the gene expression of the SREBP targets,such as HMG CoA synthase and the LDL receptor,was slightly increased, but then the mRNA levels of both SREBPs and their ... Authors Journal compilation ª 2011 FEBSGlutamine enhances the mRNA levels of SREBP family membersThere are a couple of possible explanations for the glu-tamine-mediated promotion of SREBP ... functions. The most likely are, first, an increase in the gene expression of SREBPs, and second, the enhancement of SREBPprocessing by glutamine. We therefore investigated the effect of glutamine on the...