... twin to the umbilical vein ofthe other. This abnormal connectioncan cause serious complications including loss of the pregnancy. GALE ENCYCLOPEDIAOFGENETIC DISORDERS 7Acardia The GALE ENCYCLOPEDIA ... physician reported the condition in a family, where it was observed in the father and his brother, butnot seen in the father’s mother or his wife. Both the fatherand brother would sneeze twice ... activity. Theseindividuals have no symptoms of AKU. However, theyare carriers of AKU and can pass the gene on to their off-spring.All ofthe offspring of two parents with AKU willinherit the disorder....
... implyendorsement ofthe editors or publisher.Errors brought to the attention of the publisher and verified to the satisfaction of the publisher will be corrected in futureeditions. The GaleEncyclopediaof ... medication is often prescribed inorder to lessen the nerve inflammation. Use of high doses of steroids can often produce a rapid diminishing of the symptoms. Other kinds of treatment depend on the nature of ... Studies include the role of dopamine in response to alcohol, and the effects of another neurotransmitter, serotonin, in alcoholism.Prognosis The prognosis depends on the motivation ofthe pa-tient...
... direct the guide wire to the correct location.Once it is in position, the needle is then removed, and acatheter is threaded over the length ofthe guide wire untilit reaches the area of study. The ... number of doses of triptans per month. Patients whoneed more doses either must have their doctors try to get the insurance company to authorize them, or the patientsmust pay the full price ofthe ... role in the progression ofthe disease. The accumulation of dam-age and loss of brain cells eventually results in the failure of many different organ systems in the body. According to the National...
... location of the defective chromosome. Autosomal dominant inheritancerequires the presence ofthe mutation in only one of the two copies of a gene (maternal or paternal) to trigger the onset ofthe ... decompression) Surgi-cal removal of a piece ofthe bony roof ofthe spinalcanal known as the lamina to increase the size of the spinal canal and reduce pressure on the spinal cordand nerve roots.Spinal ... Arnold-Chiarimalformations. One hypothesis is that the base ofthe skullis too small, forcing the cerebellum downward. Anothertheory focuses on overgrowth in the cerebellar region. The overgrowth pushes the cerebellum...
... The process of atherosclerosis causes a hardening ofthe walls of the arteries and, in the case of atherosclerosis in the carotid artery, results in a carotid stenosis that reduces the flow of ... stenosis is the medical description ofthe nar-rowing or constriction ofthe carotid artery. The artery islocated in the neck, and the narrowing ofthe artery iscaused by the buildup of plaque ... 50% of these strokes are thought to be the result of carotid stenosis.Causes and symptoms The cause of carotid stenosis is the buildup of plaqueon the inner wall ofthe carotid artery. The...
... gen-eral health ofthe patient.Clinical trialsAlthough there are no clinical trials for treatment of CCM ongoing as of early 2004, much ofthe current re-search focuses on the genetics ofthe disorder. ... Page 241 214 GALE ENCYCLOPEDIAOF NEUROLOGICAL DISORDERS Cerebral circulationIn the embryo, the components ofthe circle of Willisdevelop from the embryonic dorsal aortae and the embry-onic ... color of these regions produces an axon-dendrite shape that is rem-iniscent of a butterfly. The nerves ofthe spinal cord correspond to the arrangement ofthe vertebrae. There are 31 pairs of nerves,grouped...
... symptoms The cause of dermatomyositis is a disruption in the functioning ofthe immune system, although the precisedetails ofthe malfunction are not yet known. While the basis ofthe disease ... Sometimes there can be accumulation of calcium as hard bumps underneath the skin in the region of the rash. The skin may break open and become veryitchy, to the point of disturbing sleep. The other ... Ac-cording to the National Institutes of Health (NIH), about42% ofthe population ofthe United States will complain of dizziness at some point in their lives. In the UnitedStates, the cost of medical...
... byunderactivity ofthe pituitary gland.Pituitary gland The most important ofthe en-docrine glands (glands that release hormones di-rectly into the bloodstream), the pituitary is locatedat the base ofthe ... tsetse fly is the appearance of apainful red sore (chancre) at the site ofthe bite.A type of diagnosis called phase diagnosis can beused to help determine the level of advancement ofthe dis-ease. ... hunger in the Sub-Saharan region of Africa have led to difficulty in control-ling the spread ofthe tsetse fly and the disease.Treatment The choice of treatment depends on whether the dis-ease...
... especiallyaround the neck. Because the seizure occurs in the setting of a fever, the main target of therapy is to bring the feverdown. Removing the clothes and applying cool washclothsto the child’s ... sample of cells is collected from around the fetus. These cells are then tested for chromosome ab-normalities or other genetic diseases.Cornea The transparent structure ofthe eye over the lens ... set of therapies is possible if the idea of gene therapy includes the use of DNA for pa-tient treatment in ways other than inserting new genesinto cells. One example is the drug Gleevec that was...
... contraction of the facial muscles limited to one side ofthe face. The eyelids are involved, and upturning ofthe corner of the mouth is observed. The patient may have facial twitchingduring periods of ... within the skull caused by extra tissue orfluid in the brain.Papilledema Swelling ofthe optic disc, where the optic nerve enters the eyeball, or elevation of the optic nerve, and indication of ... Page 432 GALEENCYCLOPEDIAOF NEUROLOGICAL DISORDERS 433HydrocephalusKey TermsCerebrospinal fluid (CSF) The clear fluid made in the ventricular cavities ofthe brain that bathes the brain...
... investigations of monoclonal antibody therapy, the genetics of lupus, qual-ity -of- life improvement, ultraviolet light therapy, stem-celltransplantation therapy, the mechanisms of kidney andbrain ... least the tenth century A.D. The term erythematosus was first attached to the diseasein the 1850s, and it refers to the patchy congestion of skincapillaries with blood (erythema) that often ... and dilate the pupil.Nystagmus Involuntary, rhythmic movement of the eye.Polydactyly The presence of extra fingers or toes.Retina The light-sensitive layer of tissue in the back ofthe eye that...
... 524 GALE ENCYCLOPEDIAOF NEUROLOGICAL DISORDERS MeningesAnatomy The outer surface ofthe dura adheres to the skull,while the inner surface is loosely connected to the arach-noid layer. The ... is the spinal canal, where thereis normally a thin layer of fat and a network of blood ves-sels between the dura and the bony portion ofthe vertebrae.There is normally no space between the ... paresthetica is the result of pressure on the lateral femoral cutaneous nerve, and subsequent inflam-mation ofthe nerve. The point of pressure or entrapmentis usually wherethe nerve exits the...