... craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI.2-8 Presently, th e European BrainInjury Consortium andBrain Trauma Foundation ... refractory intracranial hyper-tension after traumaticbrain injury. Child Nerv Syst 2006;22:1268-1274. 47. Dickerman RD, Morgan JT, Mitller MA. Decompressive cra-niectomy for traumaticbrain injury: ... Taylor A, Butt W, Rosenfeld J, et al. A randomized trial of very early decompressive craniectomy in children with traumatic brain injuryand sustained intracranial hypertension. Child Nerv Syst...
... angiogenesis andbrain recovery (Fig. 3). Becausesimilar signals and substrates are involved, one willhave to be very careful in terms of understanding how and when these injury- into-repair ... role for JNK in CNS dis-ease and repair [64]. JNK signaling is involved in neu-ronal precursor cell migration, microtubule assembly and axonal guidance during brain development. After injury, this ... reinter-preted in the context of angiogenesis in the brain. Is itpossible that some of the acute neurovascular events in the brain after stroke represent an endogenous attemptby the brain...
... why are pericytesabundant in the brain vasculature? Brain pericytesmay perform specialized roles involved in the develop-ment and maintenance of brain vessels. First and fore-most, pericytes ... main-tenance of BBB, modulate neurovascular coupling and maintain several parts of brain homeostasis. In thisminireview, we focus on the active functions of astro-cytes in regards to brain ... dysfunction.Cell–cell interaction in theneurovascular unitAs discussed, all types of cells in the brain haveunique roles and coordinate with each other to main-tain brain homeostasis and enable proper...
... VEGF-D, binds and activates thisreceptor, resulting in the proliferation and migrationof lymph ECs and lymphangiogenesis [13].Angiogenesis inbrain diseases Brain strokeStroke is induced through: ... considered. Brain edemamay increase pressure in the cranial cavity and brain tissue, resulting in suppression of blood flow in thevessel network. Therefore, it is not easy to control theadministration ... cells and astrocytes, and the tight junctions of vascular endothelial cells (ECs) in the BBB are well organized with claudins and ZO-proteins through a decrease in angiogenesis signaling and an increase...
... and Pardridge, W. M. (1998) GLUT1glucose transporter: differential gene transcription and mRNA binding to cytosolic and poly-some proteins inbrainand peripheral tissues. Brain Res. Mol. Brain ... oxygen (CMRO2) and glucose(CMRglucose) in whole brainandin visual cortex, under resting conditions and during stimula-tion with a reversing checkerboard stimulus. Under resting conditions, ... close coupling between local bloodflow and neuronal activity, and several theories have been put forward to explain theseinteractions. The special status of the brainin having its own insulated...
... seriousinfections. Inducible resistance to clindamycin may be present in staphylococci (ie, they may be D-test positive); for thesestrains, clindamycin should not be used in high-inoculuminfections ... rhinovirus, RSV, human metapneumovirus, para- in uenza viruses, in uenza A and B viruses, adenovirus,coronavirus, and human bocavirus), and bacteria (includingS. pneumoniae, H. in uenzae, and ... wheezing in the absence of fever or hypoxemia.Abdominal pain is occasionally the predominant presentingcomplaint in children with CAP, especially for those ,5yearsofage. Although routine chest...
... Saline Cefepime Cefepime + HBO Cefepime 4 p.m. Sacrificing Induction of sepsis Rats in the Control, HBO and OT groups re-ceived intraperitoneal inoculums of 1 ml saline con-taining ... CA, USA for cytokines; and USCN Life Science Inc., Wuhan, China for MPO). Histologic evaluation Lung tissues were fixed in formalin for 24 h, embedded in paraffin and cut into 4 µm sections. ... were stained with hematoxylin and eosin (H&E) and examined under light microscope. Each slide was evaluated by two expert investigators blinded to the experiment groups. Lung injury was...
... ampicillin and intermediate to ampicillin/sulbactam. It was sensitive to the cephalosporins (cefazolin, cefotaxime, and cefepime), the fluoroquinolones (ciprofloxacin, levofloxacin), the aminoglycosides ... (amikacin, gentamicin, and tobra-mycin), meropenem, pipercillin/tazobactam and trimethoprim/sulfa. At this point, the patient was started on meropenem. The initial CT scan of the brain done ... community-acquired ori-gin, absence of underlying hepatobiliary diseases, and the presence of other invasive complications includ-ing endophthalmitis, suppurative meningitis, brain abscess, necrotizing fasciitis,...