... presence of DM were the independent predictors of CVD inthe earlier stages of CKD (Table 4). Table 1: Characteristics ofpatientswith CKD stage II to IV excluding patient with history of renal ... Results were reported as p values and Odds Ratios with 95% confidence intervals. All analyses were conducted with the use of STATVIEW software. RESULTS The patients included 52% male and 48% ... S. Albumin: 0.0365 0.554 (0.391-0.962) DISCUSSION The majority ofpatientswith CKD have severe manifestations of CVD by the time they need mainte-Int. J. Med. Sci. 2008, 5 366International...
... organ involved, all of them werecounted independently; �, 2 patientswith intestinal TB diagnosed basedon typical colonosopic findings and the other 2 patientswith TB laryn-gitis without ... extrapulmonary involvement inthe elderly couldresult from the small number ofpatients older than 60 yr (61 patients, 19.1%) in this study. In this setting, a small change in the number ofpatientswith ... higher inthe elder-ly (28). In addition, the lower risk of EPTB inthe elderlydoes not support immunity as a determinant ofthe spread of tuberculous bacilli to other organs because ofthe higherincidence...
... an audit of financial statements in accordance withthe ISAs. These additional responsibilities are not dealt withinthe ISAs. They may be dealt withinthe pronouncements ofthe International ... scope ofthe ISA, including how the ISA relates to other ISAs. • The subject matter ofthe ISA. • The respective responsibilities ofthe auditor and others in relation to the subject matter of ... example, assessing the reasonableness ofthe estimates made by management in preparing the financial statements. A24. The distinguishing feature ofthe professional judgment expected of an auditor...
... neuroserpin decrease.All determinations were carried out in a laboratoryblind to the clinical outcome and neuroimaging findings.Endpoints The primary endpoint was the decrease of neuroserpinlevels ... atotal of 129 patients were finally included inthe st udy.This research was carried out in accordance with the Declaration of Helsinki ofthe World Medical Associa-tion (2000) and approved by the ... Neuroserpin was usedas a continuous variable since there was a linearity of the odds ratios for outcome. T he influence of neuroserpindecrease at 24 h on serum levels of molecular markers of brain injury...
... 12-D pattern ofthe silver stained gel image ofthe master gel image. 2-D pattern ofthe silver stained gel image of a master gel image containing the spot information of all investigated samples. ... accumulation of genetic defects [25,26].Interestingly, there were only marginal differences in the expression profiles comparing patient to patient. This wasalso observed in studies withpatientswith ... [27].Expression ofthe plasminogen activator inhibitor-2 (PAI-2) was only found inpatients E and F withthe subtyp FABM0 and M4, respectively. This finding is inline with datafrom the PAI-2 serum...
... study. Other approaches for introducingIL2 into the tumor environment include injection of the cytokine intratumorally [17] and administering intratu-moral injections of adenovirus encoding IL2 ... patientsin GD2 staining on melanoma cells andincreases in staining for S100. Whether this decrease in GD2 staining intensity represents antigen downregulationversus steric hindrance from the ... purposes)immune-activating cytokines over the first 3 days of eachtreatment cycle. Our results show an increase in serum lev-els of sIL2R, IL10, and neopterin post-dosing. These find-ings may suggest the induction...
... participated inthe design ofthe study and performed the statisticalanalysis and interpretation of data, and drafted the manuscript; MLparticipated inthe design ofthe study and the statistical ... wasinvolved in revising the manuscript critically for important intellectualcontent; SV made substantial contributions to the acquisition ofthe data,was involved in drafting and revising the ... ion of utility values,rather than a single imputation as performed here.Furthermore, the ability to predict the SF-6D and EQ-5D from the HAQ is complicated by the weighting of items in the...
... sizes of trials andto make treatment decisions without the understandingthat the point estimate of 1.5 is the best estimate of the minimal important difference and that the limits of the CIs ... linear regression analysis where the instrument of interest is the dependent and the anchors the independent variable. Using the equation one canestimate the minimal important difference ofthe ... important difference of the HADS it is not known[11] The concept ofthe minimal important difference the smallest difference inthe outcome of interest thatinformed patients or their proxies perceive...
... improvements in all SF-36 scales, the greatest baselineto endpoint improvements (range of trial durations: 10 to16 weeks) were seen inthe Bodily Pain and Social Functionscales. These findings are also ... by clinicians and patients [2]. The objective of this secondary analysis was to evaluate the effect of adalimumab on initial improvement in HRQOL for patientswith psoriasis compared with the general ... evaluating the effect of adalimumab inpatientswith psoriasis (N = 1,205). Patientswith moderate to severe psoriasis were randomized in a 2:1 ratioto adalimumab 80 mg (two 40 mg injections administered...
... and the other37 patients lost between 10 and 27 letters). Analyses com-paring subgroups ofpatientswith different levels of visionloss within this group ofpatients could help identifywhether ... signifi-cantly associated withthe VFQ-25 scales in any of the models.Comparing change in individual VFQ-25 items among the five ETDRS change groupsMean change in each individual item ofthe VFQ-25 wascomputed ... this link over time. Thus, the purpose of the current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patients with diabetic retinopathy. Patients...
... patients were defined. Inthe absence of published thresholds, the following groups ofpatients were defined based on the distribution ofthe changes in both the weekly sleep inter-ference and pain diaries ... an11-point numeric self-administered rating scale rangingfrom 0 (no pain) to 10 (worst possible pain). At the end of the baseline phase, a mean ofthe daily pain scores wascalculated; patientswith ... how their neuropathic pain had interfered with their sleep. It consists of a single-item with an 11-pointnumerical rating scale, ranging from 0 (pain does notinterfere with sleep) to 10 (pain...
... pain rating of > 2 on an11-point numerical rating scale (NRS) to enable enroll-ment of individuals with a broad range of pain severity,since another outcome of this study was validation of ... evaluated withthe domains that areassessed by the MOS-SS. The psychometric properties ofthe MOS-SS have beenevaluated inpatientswith a variety of conditions charac-terized by pain including ... There-fore, the purpose of this study was to evaluate the test-retest reliability of a one-week recall period ofthe MOS-SScompared withthe four-week recall period in patients with FM.MethodsThe...