the shaping of controlled release drug product development by emerging trends in the commercial regulatory and p
Evaluation of advanced paclitaxel drug delivery implants for controlled release post surgical treatment against glioblastoma multiforme in the brain
... staining and preparations, and A/Prof Ong Wei Yi, Dept of Anatomy, NUS, for his valuable inputs and time on experiment design and concept Final thanks go to Prof Nick Sahinidis, UIUC, and A/Prof ... was inserted to a depth of mm from the brain surface and retracted The foam rod was then inserted completely into the incision created The scarp of the rat was then closed by suturing and the ... making based on the specific circumstances in the operating theatre The in vitro release profile of the 10% Paclitaxel loaded PLGA 50:50 foams in the form of discs and rod (rods will be used in...
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Governance and the Success of U.S. Community Banks, 1790-2010: Mutual Savings Banks, Local Commercial Banks, and the Merchants (National) Bank of New Bedford, Massachusetts doc
... commercial places” and kept in the hands of “men skilled in commercial affairs, and having their interests intimately blended with the commercial business and prosperity of the country.”121 The Merchants ... Franklin and the Invention of Microfinance (London, 2010) 105 “A Plan for the Support of the Poor, and for the Relief of the Necessitous,” Miers Fisher Papers, 1790?, Historical Society of Pennsylvania, ... Citizen, An Appeal to the Public on the Conduct of the Banks in the City of New York (New York, 1815), 5-7; An Inquiry Into the Causes of the Present State of the Circulating Medium of the United...
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Báo cáo khoa học: In vivo cross-linking of nucleosomal histones catalyzed by nuclear transglutaminase in starfish sperm and its induction by egg jelly triggering the acrosome reaction pdf
... lyticus protease I, and the digests were then separated by RP-HPLC (Fig 6) A single fluorescent peak was obtained, and the corresponding peak in the UV-absorbance profile was well resolved from the ... subjected to SDS/ PAGE on a 15% gel, followed by staining with CBB or immunoblotting Results Presence of p2 8 in chromatin The purpose of this study was to develop a better understanding of the molecular ... significant increase in the content of p2 8 in the sperm nucleus, possibly through the acrosome reaction-induced activation of nuclear transglutaminase by an increase in the intracellular concentration of...
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Báo cáo "Thermomechanical characteristics of rigid poly(vinyl chloride) crosslinked by a peroxide in the presence of trimethylolpropane trimethacrylate " pdf
... difference of softening point between the uncrosslinked - and crosslinked PVC samples is 16oC Among the samples crosslinked by DAPC and TMPTMA, the sample containing 0.2 phr of DAPC and 15 phr of TMPTMA ... of PVC chains So, the crosslinked PVC samples are more difficult to be softed and penetrated Among the samples crosslinked by DAPC and TMPTMA, the sample containing 0.2 phr of DAPC and 15 phr of ... samples This is explained by the crosslinking PVC in the presence of DAPC and TMPTMA as mentioned above At any concentration of TMPTMA, a maximum of the PVC samples also appears at 0.4 phr of...
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Báo cáo lâm nghiệp: " Predator/prey ratios: a measure of bark-beetle population status influenced by stand composition in different French stands after the 1999 storms" pps
... L spp Picea A Dietr spp Abies Mill spp Larix Mill spp Pseudotsuga menziesii Carr Fagus L spp Quercus L spp Fraxinus L spp Betula L spp Acer L spp Alnus Gaertn spp Sorbus L spp Tilia L spp Empty ... diversity index (SHDI) and catches of T formicarius and of I typographus; (b) arcsine-transformed proportion of pines (PROP_PIN) and catches of T formicarius and of I typographus; in a 500 m radius Landscape ... ratios, and both the Shannon diversity (SHDI) index and the proportion of pines (PROP_PIN) around the 10 bottle-traps of each site The comparison of predator/prey ratios between sites and years...
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Báo cáo khoa học: "The response of dehydrated Douglas fir (Pseudotsuga menziesii) pollen to three in vitro viability assays and their relationship to actual fertility" doc
... FSPC values (Webber, 1991; and unpublished data) compared to more passive pollinator types (ie, paintbrushes and misting pollinators) It should be possible, then, to influence the proportion of ... the proportion of Class grains but there was a significant decrease over the 3 0P1 0B and 4 0P1 0B media Correspondingly, the proportion of Class grains increased significantly over the media types ... lower proportions of Class grains (28.3 and 10.5%, respectively) There was no significant difference between the proportion of Class grains for the 1 0P1 0B and 2 0P1 0B media but the proportion of...
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Báo cáo y học: "Characterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivity" docx
... showing the MAp17 and the N-terminal CAp24 domain of the unprocessed Pr55Gag Ribbon diagram of the MAp17 [33] and CAp24 [34] depicting the structural rearrangemts that takes place in the N-terminal ... Coulter) and the precipitate was resupsended in 50 mM Tris pH8.0, 30 mM NaCl, and mM EDTA The purity and integrity of each CAp24 protein was finally analyzed by SDS-PAGE In order to increase the purity ... mutant CAp24 proteins Mutant and wild type CAp24 proteins were induced for in vitro CAp24 tubular formation (see Fig 3) At the end of the experiment, the proteins were fixed in freshly prepared...
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Báo cáo sinh học: "Effects of data structure on the estimation of covariance functions to describe genotype by environment interactions in a reaction norm model" potx
... values of EP of groups of herds 1, and in the case of herd dependent use of sires Averages and standard deviations of EBV across replicates are shown in Table VIII The group of sires represented the ... international breeding value estimation The objective of this paper was to investigate the in uence of definition of EP and levels of preferential sire use in herds on expected breeding values and estimated ... example in international breeding value estimation, or to investigate the importance of G × E In applications in dairy cattle, an EP is usually calculated as the mean phenotypic performance of...
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the difficulties of non-major of english at haiphong foreign language center–haiphong university in learning listening skill and some suggested solutions = những khó khăn của sinh viên không chuyên anh
... quickly the speaker speaks They feel that the utterances disappear before they can sort them out “They are so busy working out the meaning of one part of what they hear that they miss the next part ... skill in English? And how they distribute their time in practicing the four skills of language learning: listening, speaking, reading and writing? The following chart shows the differences in time ... maintain the students‟ focus on their tasks Furthermore, the answers to the prepared questions in the pre-listening stage could be the actual main ideas of the listening task In this way, prediction...
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The effectiveness of visual aids to vocabulary learning by 10th graders in Le Quy Don High School, Hai Phong = Tính hiệu quả của Giáo cụ trực quan đối với việc
... to find out the meanings of the others that lead them to gain an overall scene of the story of theme That is the way of teaching reading linking together in a process To sum up, “for helping ... number of cards can be displayed at the same time: by asking several students to hold them, by sticking them to the board, by clipping them to a wire, by propping them to a shelf, by using a sentence ... general introduction of the study with the specific reference to the rationale, the aims, the methods, the significance and the design of the study Part B: Development The development of the study...
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Báo cáo Y học: Expression and distribution of penaeidin antimicrobial peptides are regulated by haemocyte reactions in microbial challenged shrimp pptx
... the lysis of the haemocytes and the release of cytoplasm content, as suggested by the later appearance in the preparation of numerous ghost cells and penaeidin immunoreactivity in preparation ... Immunostaining was observed by confocal microscopy The percentage of haemocytes expressing penaeidin corresponds to the ratio between the number of penaeidin riboprobe-positive cells and the total ... per slide and three slides per shrimp were counted and each value represents the mean of five shrimps ± SEM post-injection (Fig 5) Regarding storage of the peptides, the percentage of penaeidin-immunoreactive...
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Báo cáo hóa học: " Differential inhibition of human cytomegalovirus (HCMV) by toll-like receptor ligands mediated by interferon-beta in human foreskin fibroblasts and cervical tissue" pdf
... for HCMV inhibition and IL-8 production The effect of timing of TLR-ligand exposure on inhibition of HCMV infection production was next investigated using the concentration of each TLR-ligand that ... of HSV-2 in vaginally-infected mice was prevented by intra-vaginal application of purified TLR ligands [12,13] Similarly, intravenous injection of ligands for TLR3, -4, -5, -7, and -9 inhibit ... observed in response to LPS (Fig 2A) However, both Poly I:C and LPS induced >98% inhibition of HCMV infection when present for 24 hours in cell culture Anti-HCMV responses induced by Poly I:C and LPS...
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Báo cáo khoa học: "Survival of avirulent thermostable Newcastle disease virus (strain I-2) in raw, baked, oiled, and cooked white rice at ambient temperatures" pps
... esaesiD eltsacweN ).de( BP worbdarpS :nI eniccav esaesid eltsacweN laro fo yreviled eht rof sreirrac doof fo esu eht fo weiver A P worbdarpS 11 01-2 ,52 ,3991 dorP htlaeH minA porT elcihev a sa ecir ... ,ainavlysnneP fo ytisrevinU ,stsigolohtaP naivA fo noitaicossA naciremA ,361-651 pp de ht4 snegohtaP naivA fo noitacifitnedI dna noitalosI eht rof launaM yrotarobaL A ).sde( MW deeR ,EJ nosraeP ... dekooc eht roF ylevitcepser ,ecir dekab dna dekoocnu rof gol 6.1 dna gol 2.1 fo pord rehtruf a saw ereht ,C 52-22 ta h 42 rof egarots retfA ylevitcepser ,gol 5.0 dna 3.0 yb ylno deppord sretit...
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Báo cáo sinh học: "Trends in antibiotic susceptibility patterns and epidemiology of MRSA isolates from several hospitals in Riyadh, Saudi Arabia" doc
... widespread use Keeping these resistotype data in mind while prescribing antibiotics for MRSA infected patients should aid in the prevention of its spread and abiding by the same principles kingdom-wide ... Additional investigation of laboratory derived vancomycin-resistant strains demonstrated down-regulation of certain penicillin-binding proteins, including PBP2A Quinupristin/dalfopristin (Synercid) ... emergence and spread of resistance Eliminating inappropriate antibiotic use and promoting more judicious use are essential parts of the solution As depicted in table and figure 1, 78.9% of the isolates...
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Báo cáo y học: "Effectiveness of counseling for anxiety and depression in mothers of children ages 0-30 months by community workers in Karachi, Pakistan: a quasi experimental study" ppsx
... freely in the community In addition, they were trained in monitoring the growth and development of the indexed baby by measuring weight, height and head circumference They were also trained in using ... the date of the last menstrual period from women in the reproductive age group Those found to be pregnant were informed of the objectives of the study and were invited to participate in the study ... in the program, irrespective of whether they were anxious/depressed or not or whether they were being counseled or not, were instructed in healthy child rearing practices and the growth and development...
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Báo cáo hóa học: " Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve" pptx
... tissueelectrode interface in case of in vivo applications In future, enabling bionanotechnology should open new perspectives in the design of the NI, allowing the integration of multisites for specific and ... scheme of the CNT array-based system for drug delivery proposed in this study is depicted The main structure is composed by the CNT array, embedded with the thin film of alginate entrapping NGF to induce ... a constant pressure of Pa, using 99.99% pure SiO2 target and 99.999% pure argon as sputtering gas) CNT Array: Properties, Imaging and Coating Alginate Thin Film Design, Production and Characterization...
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Báo cáo lâm nghiệp: "Growth and nutrition of container-grown ponderosa pine seedlings with controlled-release fertilizer incorporated in the root plug" docx
... experiment to investigate the applicability of a number of different controlled- release fertilizer products The fertilizers were either applied into the root plug of containerized ponderosa pine ... rivers if the products were formulated and designed appropriately (nutrient composition and release characteristics), and were applied in a proper amount, placement method and timing Moreover, controlledrelease ... regime, on the growth and nutrition of containerized ponderosa pine stock during the 9-month growing period Our hypothesis was that, in the greenhouse, incorporating extra controlled- release fertilizer...
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Development of controlled drug delivery systems using uniform nanoporous materials as matrices
... rate of release is dependent upon the diffusion coefficient of the drug in the polymer and upon the initial drug load The diffusion coefficient is dependent upon the properties of the drug and the ... first prepare the polymer matrix in an appropriate mold and then achieve the desired 19 / Literature Review drug load via sorption of the drug from a saturated solution of the drug in an appropriate ... rate of swelling (and the rate of drug release) depends on the hydrophobic/hydrophilic balance of the polymeric matrix and the degree of crosslinking (Brondsted et al., 1991) The release of water-soluble...
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MANAGING THE UNCERTAINTY ASPECT OF RELIABILITY IN AN ITERATIVE PRODUCT DEVELOPMENT PROCESS
... manage the risk and uncertainty in IPDP is presented in chapter In Chapter 5, a prototype method for managing risk and uncertainty in IPDP is developed and is applied in industrial cases in chapter ... different types of product development process are covered in the next section 2.5 Types of Product Development Process There are several definitions of a product development process (PDP) in literature ... etc Production then realizes the product design into a physical product in a manufacturing plant It encompasses production equipment preparation, production line set up, training for new operators...
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Mining of textual databases within the product development process
... to the domain of the design 2.2.4 Production Ramp-Up Comparatively speaking, the production phase of the PDP has the most number of data mining applications The primary reason for this is the ... predict the effects of design changes, and determine the best design parameters by analysing the effect of drop test 21 Data Mining Within the Product Development Process Chapter In their paper, ... (MNCs) In particular, the purpose of these databases, the phase of the PDP in which these databases are used, their structure and content, the quality of information in them and the potential use of...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25