the regulation mechanism of the systems is programmed in each component
Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"
... and manuscript revision.JK was involved in the design and statistical analysis of the study. MS conceived and coordinated the study and wasinvolved in the interpretation of the data and manuscript ... involved in drafting the manuscript.MG participated in analysis and interpretation of the data and in drafting the manuscript. PS, JS and MV contributed to the conception and design of the study ... The Netherlands7Anaesthsiologist-intensivist, Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands8Internist-intensivist, Research...
- 7
- 722
- 0
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... complexes of cyclin-dependent kinases (cdks)and their corresponding cyclins. A prominent example of such a pair is cyclin B and cyclin-dependentkinase 1 (cdk1 ⁄ Cdc2) controlling the checkpointbetween ... However, as in most other CDE ⁄ CHRpromoters, mutation of the CHR results in a smallerremaining cell cycle -regulation than alteration of the CDE [37]. Interestingly, the core of the human Tome-1promoter ... BubR1 is a protein importantfor spindle checkpoint activation. Expression of the BUB1B gene coding for BubR1 is undetectable in G1,but peaks in G2⁄ M. Recently, the regulation of the BUB1B...
- 17
- 876
- 0
Tài liệu Research " The Dissertation Committee for Fang Yin Certifies that this is the approved version of the following dissertation: Business Value of Information Technology in the Internet Economy " doc
... by other companies. The cost of sales of most physical dot coms consists of the cost of merchandise sold and inbound/outbound shipping. There are other important distinctions between these ... years in business. t is included in the model to control for the maturity of a company. Companies operating in the Internet space are expected to improve their conduct of business over time. Since ... used to distinguish between the ability of players to leverage the new Internet economy. The key criterion used in this study is the type of product or service a firm offers on the Internet....
- 163
- 731
- 0
Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... results indicated that IPU is an anomer-invertingenzyme (Fig. 5A). In the case of inverting enzymes, a single displacement mechanism has been proposed [6,17,19–21]. In this mech-anism, two ... is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study areshown in Fig. 3. To elucidate the mechanism of the substrate recognition of IPU, ... concentra-tion of isomaltose is effective for the induction of amylasesynthesis, the low activity of IPU may be suitable for control of this regulation. AcknowledgementsWe thank Mr Masahiro Mizuno for his...
- 8
- 551
- 0
Tài liệu Báo cáo khoa học: The mechanism of a-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase doc
... hatelimination of indole in the tryptophanase reaction is realized by a concerted SE2 mechanism, involving simul-taneous protonation of the C3atom of the indole moietyand breakdown of the ... acid the interaction of the distal carboxylic group with Arg100 takes place in the quinonoid intermediate structure [18], but not in the external aldimine. The observed predominant formation of the ... group of the s ubstrate, when the external aldimine is formed. The anchoring of a-carboxylateand a-amino group in the external aldimine definesautomatically the positions of the a-proton and the...
- 7
- 532
- 0
Tài liệu Báo cáo khoa học: Unraveling the catalytic mechanism of lactoperoxidase and myeloperoxidase A reflection on some controversial features Elena Ghibaudi and Enzo Laurenti docx
... formulated a hypo-thesis that describes an integrated vision of the catalytic mechanism of both enzymes. The main points are: (a) are-evaluation of the role of superoxide as a reductant in the catalytic ... addressing each of these questions, we will proposea new hypothesis that describes an integrated vision of the catalytic mechanism of MPO and LPO.A brief survey of the absorption features of MPO, ... and in the etiology of some pathologies [57]. In the light of the work by De Pillis et al. [50,58], we would not exclude that the radical plays a role in the autocatalytic binding of hemeto the...
- 10
- 529
- 0
Tài liệu Báo cáo khoa học: The single tryptophan of the PsbQ protein of photosystem II is at the end of a 4-a-helical bundle domain docx
... possesses the samecharacteristics of the interior of the protein matrix. The script a is the peak–peak distance between the maximumat %287 nm and the minimum at %283 nm, and the script b is the peak–peak ... twoout of six tyrosine residues are buried in the protein. The arrangement of four tyrosines is shown in Fig. 5C, while the other two in the Nt-domain are probably solvent exposed in the flexible ... role in maintaining the overall stability of PSII. PsbQ has beenreported to be thermostable, with a melting point of % 65 °C[74]. This is compatible with some of the features found in the PsbQ...
- 12
- 550
- 0
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... with the sameregion of the arginases (Fig. 4). Since the arginase loopcontains residues that interacts with the a-carboxylategroup of the substrate arginine [13], and this is the part of the ... of agmatine to putrescine and urea [1].Agmatine, which results from decarboxylation of arginineby arginine decarboxylase [2], is a metabolic intermediate in the biosynthesis of putrescine and ... deletions in the agmatinasesequence were modelled using the DGLOOP set of options in WHATIF; the whole loops and the two connecting aminoacids at the beginning and the end, were mutated to glycinesand,...
- 5
- 475
- 0
Báo cáo khoa học: The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue potx
... H2O2. This shows that this position of OD2 in the native is not appropriate for involvement in the reac-tion. In contrast, in D171N-CN, the distance, 3.46 A˚ ,is less than in the native. The position ... That is because this difference is caused by the differencebetween the positions of hydrogen bond partners of OD2 in the native and ND2 in D171N-CN. In the native, the distance, 4.06 A˚, is ... of D171N-CN is shown as Asp171. To avoid misunderstanding, only the heme of the native is shown in white. The position of the CN carbon mimics the position of the proximal oxygen of H2O2....
- 8
- 392
- 0
The Internet of Things - How the Next Evolution of the Internet Is Changing Everything doc
... Cisco IBSG © 2011 Cisco and/or its affiliates. All rights reserved. 01/11 White Paper The Internet of Things How the Next Evolution of the Internet Is Changing Everything The Internet of ... securely. The web, on the other hand, is an application layer that operates on top of the Internet. Its primary role is to provide an interface that makes the information flowing across the Internet ... threshold of connecting more objects than people to the Internet, a huge window of opportunity opened for the creation of applications in the areas of automation, sensing, and machine-to-machine...
- 11
- 772
- 6
Báo cáo khoa học: Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter potx
... lm of the competitor nucleotide. In this case, the bindingconstant Kdiss of mant-ATP (in the absence of competitor)increases to the apparent binding constant Kappdiss (in the pres-ence of ... [L0], the binding constant of the nucleotide can be determined from the slope of the linear plot of the apparent binding constants Kappdissand [L0]. With the ligand ATP, a binding constantKligdiss of ... asKappdiss¼ Kdiss1 þL0½Kligdiss !ð4Þ in which Kdissrepresents the binding constant of the mant-ATP complex in the absence of competitor, andKligdissrepresents the binding constant...
- 15
- 441
- 0
Báo cáo khoa học: Transthyretin and familial amyloidotic polyneuropathy Recent progress in understanding the molecular mechanism of neurodegeneration pdf
... occupancy of the first bindingsite [68]. TTR is also involved in the transportation of retinol by forming a complex with the smaller retinol-binding protein (RBP) [69,70]. The TTR–RBP–retinolcomplex ... the inside of the protein [98]. Dis-location of the C and D strands from their nativeedge region may result in the formation of a newinterface involving A and B strands which is open forintermolecular ... to the mechanism of the molecular patho-genesis of FAP and suggest new avenues for therapeutic intervention. It is increasingly recognized that there are common features of a number of protein-misfolding...
- 14
- 488
- 0
Báo cáo khoa học: Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens potx
... domains consist of a cen-tral six-stranded parallel b-sheet flanked by a varyingnumber of a-helices. Residues involved in binding of the cofactor ThDP are located at the C-terminal ends of the ... domains, suspend-ing a comparatively mobile thiazolium ring between them. While the resi-dues binding the two ends of ThDP are well conserved, the lining of the active centre pocket around the ... the C2 atom of the thiazolium ringand the N4¢ atom of the pyrimidine moiety. A super-position of the cofactors is depicted in Fig. 5 revealinga remarkable conformational similarity. The diphos-phates...
- 10
- 454
- 0
Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy pptx
... of the CaM-binding domain probed by W242W242 dominates the intrinsic fluorescence emission of the protein [20]. It is situated in the middle of the 72-amino-acidsegment responsible for 90% of ... is the ÔcoreÕ of the CaM-binding site of the enzyme[9,16–21]. The mechanism of AC activation by CaM, and in particular the role of the conformational change resultingfrom CaM binding, remains ... foreither AC or AC–CaM. This indicates that the bound Ant-dATP is immobile in the 100–200 ps time scale. Supportingthis hypothesis, the initial anisotropy at t ¼ 0 when the probe is in the presence...
- 13
- 409
- 0
- the primary purpose of this book is to describe human blood group antigens and their inheritance
- probing the electronic structure of complex systems by arpes
- the electronic structure of complex systems
- the first law of thermodynamics states that energy in a system is
- what is the minimal length of the box
- the standard form of the equation of a circle is
- andrea damascelli probing the electronic structure of complex systems by arpes
- the purchase price of a book is 35 85
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25