... in their semantic content, but lexically they select only one of these EPs as their KEY, we propose that the semantic properties ofthe arguments ofthe verb giefien (water) in example (1) of ... focussed on (some of) the theoretical assumptions upon which the achievement of such a goal can be based realistically A presentation ofthe technical details ofthe LKB implementation ofthe grammar ... Predicates In the spirit ofthe MRS-based analysis for the German verbs gieflen and fi,illen that we have presented above, we propose that the semantic properties ofthe arguments of one ofthe most...
... months - No reduction ofthe incidence of fractures - No reduction ofthe rate of falls or the incidence of fractures No effect of serum vitamin D3 level - No reduction ofthe fracture risk (OR ... moment of time to environmental constraints [28,32] It has been suggested that the specificity ofthe mechanism of falls in the elderly, particularly the impairment of postural reactions - either ... an abnormality of processing of musculoskeletal mechanisms and of sensorimotor information in the CNS The central question is to determine whether the age-related alteration ofthe postural adaptation...
... [12, 29] They all highlight the effect ofthe summer drought on soil respiration and some of them also show the negative effect ofthe cold temperature in winter on respiration Two types of measurements ... till the end ofthe experiment, the treatment effect was highly significant (P < 0.001) The plot effect was only significant in July 1999 due to the high heterogeneity of data in the C plots The ... efflux The model ‘Temp’ explained only 6% ofthe variance ofthe soil efflux and 23% for the ecosystem respiration Introducing soil moisture in the two other model allows us to better describe the...
... that mitochondria play a keyrole in PND in Tetrahymena Unfortunately, the involvement ofmitochondria in PND has not been clarified fully To elucidate theroleofthe mitochondrion as a key effector ... observations ofthe monomeric form of DePsipher in the autophagosome together, themitochondria taken in the autophagosome might be broken, once they were incorporated into the autophagosomes These ... DNA fragments, considering the timing of uptake ofthemitochondria in the autophagosome, as discussed below Mitochondria as a possible executor of PND The process of DNA degradation during PND...
... results obtained by other groups who also point to theroleofthe connecting loop ofthe b-hairpin of defensins A combination of mutational analysis [35] and structural analysis ofthe plant defensin ... accessible residues charge ofthe b-hairpin loop, as compared with that of other domains ofthe molecule, might be a key feature for the activity of defensins It must be noted that the a-helix (residues ... plotted against the log ofthe measured MIC The aforementioned results showed that synthetic peptides corresponding to fragments ofthe MGD1 defensin reproduced the behaviour ofthe entire molecule...
... infer function ofthe protein Confirm transmission ofthe phenotype and map it Identify the mutation, and thereby prove importance ofthe gene to the phenomenon Practical application of forward and ... effector limb ofthe response During the decade ofthe 1980s, one ofthekey discoveries in sepsis research concerned therole played by soluble mediators of monocyte/macrophage origin in shock ... However, it is the cellular response to microbes that creates the septic syndrome, and a handful of specific receptors alert the host to the presence of an infection The effector limb ofthe response...
... attempts, the ‘hands-off’ intervals between interruption of chest compressions and the delivery ofthe countershock should be limited to only a few seconds [8,20] In all of these areas of concern, ... ventricular fibrillation is one ofthe greatest causes of premature mortality in many societies, the magnitude ofthe public health impact of AEDs is potentially dramatic, in terms of both life-saving and ... summary, the use of AEDs by the average person may be considered one ofthe greatest advances in critical care medicine during the past decade Similarly, recent technology has also enhanced the quality...
... PSHC, the precursors ofthe various blood cell lines The very existence of mitochondria, the main consumers of O2 entering the cells, allows us to regard these ATP-producing organelles as the major ... expression changes the erythroid differentiation of J2E cells towards the formation of less mature precursor cells On the basis of these facts, the authors of this investigation [43] drew the following ... factors starts These further reduce the capacity and/or activity ofthe mitochondrial base One may be involved in suppressing the set of Page of 11 (page number not for citation purposes) Theoretical...
... largely inaccessible for evaluation ofthe fetus and ofthe fetal testis, even if study ofthe mother (her 16 Male Reproductive Health Disorders and the Potential Roleof Environmental Chemical Exposures ... some ofthe weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment ofthe various studies and ofthe ... limitations on the scope of this review Two overviews are used to set the scene for the review First, an assessment ofthe latest evidence on the prevalence of human TDS disorders and whether this...
... turns ofthe DNA double helix yields binding ofthe two or three NF-Y complexes on the same side ofthe DNA Conservation of spacing is required for optimal promoter activity because changing the ... However, as in most other CDE ⁄ CHR promoters, mutation ofthe CHR results in a smaller remaining cell cycle-regulation than alteration ofthe CDE [37] Interestingly, the core ofthe human Tome-1 ... promoters, mutation ofthe CHR leads to a more pronounced deregulation than the alteration ofthe CDE [40] Another gene tested for its cell cycle regulation is the cellular inhibitor of apoptosis protein...
... cost-effective way of assessing health risks; • the identification of all risk points along the chain of events from the origin ofthe wastewater to the consumption ofthe produce (e.g the farm-to-fork ... personal-care products and pharmaceuticals The impacts of these are wide-ranging In the north east of Australia, run-off of agricultural herbicides caused the loss of 30 km2 of mangrove between 1999 and 2002 ... for the increasing volume of wastewater that we produce are at the heart ofthe wastewater crisis The way we produce our food uses 70–90 per cent ofthe available fresh water, returning much of...
... intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal ofthe present perspective ... which small alterations in the environment can cause drastic changes in the reactivity ofthe active species [76] Further support in favour ofthe idea ofthe involvement of a high-valent iron-oxene ... alignment ofthe CYP19 sequence with the known crystal structures of bacterial P450s, E302 was postulated to be essential to activation ofthe 19-oxo group ofthe substrate for attack by the peroxo-iron...
... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health ofthe public The Institute acts under the responsibility given to the ... and the 1970s saw tremendous swings from the latter to the former, setting the stage for another swing ofthe pendulum back to the latter as a result of disappointments with the results of diffuse ... members ofthe committee on the field visits and who provided general guidance to the committee greatly enriched the quality ofthe report: Michael Clegg, Foreign Secretary ofthe National Academy of...
... appropriate, the CAQ formed a task force on theroleofthe auditor and moved to convene investors and other financial reporting stakeholders to examine theroleofthe auditor and the value ofthe audit ... isolation The “what, whys, and hows” related to changing theroleofthe auditor has to be considered within the context ofthe overall financial reporting system, including the important roles ofthe ... evolve theroleofthe auditor to meet the needs of investors in the near and longer term In the near term, the CAQ and its member firms have developed model reports for the PCAOB and other stakeholders...
... reasonable to assume that the disruption ofthe H-bond makes the distal His less basic As a consequence the pKa value ofthe NeH ofthe distal His is lowered and the rate constant for the reaction with ... Reinheitszahl of Asn153fiAsp These spectral data together with the kinetic parameters presented below suggest that the mutations caused no significant changes in the interactions ofthe heme with the apoprotein ... inspection ofthe crystal structures of members ofthe plant, fungal and bacterial superfamily show the existence of a hydrogen bond between the distal His and an Asn (Fig 1) [3–5] The corresponding...
... rise ofthe internet and the spread of McDonalds to the establishment ofthe International Criminal Court and the emergence of global terrorism Focusing on the implications of globalization for the ... Interesting from the view of diplomacy is the aim of UCLG to gain an official status at the UN in order to promote and protect the interests of cities worldwide in all ofthe issues with which the UN deals ... theroleof cities in diplomacy We would like to thank the city ofThe Hague for its sponsorship ofthe project We would also like to extend our gratitude to the interviewees for dedicating their...
... share ofthe euro in the bond portfolios of large international fund managers, on the one hand, and the rising share ofthe euro in the stock of international bonds, on the other Looking ahead, the ... international roleofthe euro, Frankfurt am Main ECB (2002), Review ofthe international roleofthe euro, Frankfurt am Main ECB (2003a), The international roleofthe euro: main developments since the ... importantly, in the course ofthe past few years, the ECB has put in the limelight three major traits that characterise how the international roleofthe euro has unfolded so far The first is that the euro’s...
... mutants ofthe MetAP-I from E coli S Mitra et al affect the DG value for the binding ofthe rst metal ion; however, the entropic factor (TDS) for the binding ofthe rst metal ion decreases in the ... values of 90 20, 210 100 and 574 150 lm The heat of reaction, measured during the experiment, was converted into other thermodynamic parameters using the Gibbs free energy relationship The thermodynamic ... that allows the concentrations ofthe titrant and the sample to be tted to the heat-ow-per-injection to an equilibrium binding equation for two sets of noninteracting sites The Ka value, the metalenzyme...