the clinical utility of human polymerized hemoglobins as a blood substitute following acute trauma and urgent surgery
bài giảng chapter 1 overview of financial management and the financial environment
... state Charter Bylaws 1-7 Advantages and Disadvantages of a Corporation Advantages: Unlimited life Easy transfer of ownership Limited liability Ease of raising capital Disadvantages: ... quotation system keeps track of bid and ask prices, but does not automatically match buyers and sellers Examples: Nasdaq National Market, Nasdaq SmallCap Market, London SEAQ, German Neuer Markt ... corporate yield curve and the Treasury curve widens as the corporate bond rating decreases 1 - 46 Hypothetical Treasury and Corporate Yield Curves Interest Rate (%) 15 BB-Rated 10 AAA-Rated Treasury...
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Tài liệu overview of data modeling and database design pptx
... contain a null value Candidate Keys A table can have several candidate keys A candidate key is a column or combination of columns that can serve as the primary key for the table Select one candidate ... relational database and its components D Read an entity relationship model D Translate an entity relationship model into a relational database design Overview of Data Modeling and Database Design ... examples of these types of relationships in the top slide Answer: 1:1 Husband and wife; taxi and driver; machine and operator; ship and dock M:1 Orders and items; auto and occupants; plane and...
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Tài liệu overview of data modeling and database design pdf
... List and define basic types of data relationships D Define a relational database and its components D Read an entity relationship model D Translate an entity relationship model into a relational ... different functional requirements and alternate database designs by normalizing the storage of data before you create the database Benefits of Normalization D Minimizes data redundancy D Reduces ... primary key must be unique in combination, although the individual columns can have duplicates No part of a primary key can contain a null value Candidate Keys A table can have several candidate...
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Tài liệu An overview of customer satisfaction and loyalty doc
... Plans Phase 6: Tracking Phase 3: Needs and Performance Evaluation Provide Quantitative Measures of: • Importance of Key Attributes • Company Performance on Key Attributes • Competitive Performance ... six interactive phases Customer Satisfaction Measurement Process Phase 1: Mobilization Phase 4: Action Planning Define Business and Information Objectives Develop Overall Plan Gain Management ... customer satisfaction and loyalty research important? Customer satisfaction and loyalty research allows your customers to communicate with you directly about their needs, assuring you that the quality...
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Tài liệu Database Encryption – An Overview of Contemporary Challenges and Design Considerations pdf
... against the stored data may be performed by accessing database files following a path other than through the database software, by physical removal of the storage media or by access to the database ... Static leakage - Gaining information on the database plaintext values by observing a snapshot of the database at a certain time For example, if the database is encrypted in a way that equal plaintext ... Database Security – Models and Attacks 2.1.1 Database operational model As with current database systems, when discussing the model for database encryption we assume a clientserver scenario The...
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Tài liệu Báo cáo Y học: The glucose-specific carrier of the Escherichia coli phosphotransferase system Synthesis of selective inhibitors and inactivation studies pptx
... KI2/KS2 ¼ and KI1/ KS1 ¼ 0.7 These values and the transition of the Eadie– Hofstee plot from the biphasic to a monophasic shape are Table Rates of inactivation of IICBGlc Incubation of purified ... incubation time, 30-fold diluted into cold buffer, and residual PTS activity was then measured in a standard phosphotransferase assay In the lowest part of the figure are presented the residuals of ... inhibitor and Glc and assayed for uptake activity as described in Materials and methods and in the legend to Fig EIIGlc and the C-6 bromoacetyl sugars It was not observed with the C-1 isothiocyanate...
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An Overview of Consumer Data and Credit Reporting ppt
... of a credit account, and 92 percent of these had an open and active account as of the date the sample was drawn (table 1) A very small share of the individuals in the sample had only a public record ... was drawn or the gap between the date the sample was drawn and the last date they were reported is larger than any previous gap in their payment history There is another indication that many of ... including the types of credit accounts an individual has established, how long the individual has had a particular credit account, and the last time the credit account carried a balance Evaluators also...
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An overview of research, policy and practice in teacher supply and demand, 1994–2008 docx
... teachers to areas of need and/ or demand After a careful analysis and examination of available data sources, methodologies and models to analyse supply and demand, Arends concludes that: teacher ... classes have remained large and the training and recruitment of additional teachers have been sacrificed On the other hand, if the focus has been on smaller classes and lower salaries, then training ... shortages and the supply and demand challenge are an example of systemic (rather than market) failure Research over the period has reiterated that matching and modelling the supply and demand of...
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Overview of Tax Legislation and Rates doc
... assess the impacts as part of the consultation and publish a Tax Information and Impact Note alongside the draft legislation Personal taxes, National Insurance Contributions and Capital Gains Tax ... taxes and duties on a provisional basis following changes to the parliamentary timetable, whilst maintaining appropriate safeguards and allowing time for adequate parliamentary scrutiny A Tax ... have the effect of guaranteeing the value of the leased asset at the end of the lease but which also enable the amount guaranteed to be taken into account for tax relief a second time when paid...
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Structure, Properties, and Preparation Of Boronic Acid Derivatives Overview of Their Reactions and Applications
... the use of LTMP as base is quite advantageous because LDA fails to metallate this substrate and provides instead the carboxamide product of addition to the ester 1.3.1.2 Transmetallation of Aryl ... restrains its use for the large-scale preparation of boronates Standard conditions for the coupling reaction involve PdCl2(dppf ) as catalyst, with potassium acetate as the base in a polar aprotic ... used as a competitive color- and f luorescence-based assay for both qualitative and quantitative determination of saccharide binding [131] Using the ingenious ARS assay, Springsteen and Wang presented...
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Báo cáo y học: "Developments in the scientific and clinical understanding of the spondyloarthritides" pptx
... [20], and partial remission [19] (the ASAS20, ASAS40, and ASAS partial remission criteria, respectively) of clinical symptoms Andrei Calin, of Bath, UK, had started this kind of work in the early ... nonradiographic sacroiliitis These data clearly indicate that such a screening approach is feasible and effective and that patients with nonradiographic axial SpA constitute a substantial part of ... ASAS/European League Against Rheumatism recommendations on the management of AS, which are based on a thorough analysis of the available literature and on a meeting of SpA experts, were published [22] Again,...
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Báo cáo y học: "Developments in the scientific and clinical understanding of autoinflammatory disorders" doc
... Anti-IL-1 therapies Cold avoidance and anti-IL-1 therapies to monthly Elevated IgD Anti-TNF and and IgA, acuteanti-IL-1 phase response, therapies and mevalonate aciduria during attacks Variable and may ... and other ethnic groups, including Arabs and Southeast Asians The disease occurs equally in males and females and usually presents in the first year of life [44] Attacks are irregular, typically ... only the past few years after their common genetic aetiology was discovered Clinical disease is accompanied by an acute- phase response and often leukocytosis and thrombocytosis and anaemia of chronic...
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Báo cáo y học: "The role and clinical implications of G6PI in experimental models of rheumatoid arthritis" pptx
... 349:1907-1915 Sakaguchi N, Takahashi T, Hata H, Nomura T, Tagami T, Yamazaki S, Sakihama T, Matsutani T, Negishi I, Nakatsuru S, et al.: Altered thymic T-cell selection due to a mutation of the ZAP-70 ... sensitive and specific diagnostic markers for certain organ-specific autoimmune diseases These include the anti-Jo-1 autoantibodies that bind to and inhibit activity of histidyl-tRNA synthetase, and the ... expressed autoantigens are diagnostically important in organ-specific autoimmune diseases There are several clinical examples of autoantibodies against systemically expressed autoantigens that are...
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Báo cáo y học: " Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies'''' doc
... GlaxoSmithKline, and has participated in Speaker's Bureaus for AstraZeneca, TAP Pharmaceutical Products, Inc., and Santarus, Inc (San Diego, CA, USA) RHJ has received consultancy and speaker fees from AstraZeneca, ... data acquisition and interpretation JN was involved in data interpretation Data analysis was provided by GL All authors read and approved the final manuscript 12 Acknowledgements 13 This research ... (Madison, NJ, USA), and Grỹnenthal GmbH (Aachen, Germany) NJT has participated in consultant advisory boards sponsored by AstraZeneca and has received consultant's research support from TAP Pharmaceutical...
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Báo cáo y học: "Developments in the scientific and clinical understanding of inflammatory myopathies" pps
... phase of their disease, in an established disease phase before and after immunosuppressive therapies, as well as in a late chronic phase of disease Such information has provided a novel understanding ... function as professional antigen-presenting cells and are central in the development of innate and adaptive immune responses Both immature (CD 1a) and mature (CD83+ and DC-LAMP) DCs as well as their ... directed against histidyltRNA synthetase might drive autoantibody formation and tissue damage The association between autoantibodies directed against RNA-binding antigens and type I IFN activity, as...
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Báo cáo y học: "Developments in the scientific and clinical understanding of gout" docx
... in acute gout Based on these results, an open clinical study was performed to assess whether the IL-1RA anakinra had a clinical effect in acute gout In a small study of 10 patients, all patients ... of the cytoplasmic protein ASC (apoptosis-associated specklike protein containing a caspase-associated recruitment domain [CARD]) and a protein of the NLR (Nod/NACHT-LRR domains) family Because ... domain-containing-3) inflammasome and lead to caspase-1 processing of pro-IL-1β Activation of the endothelium by IL-1β increases trafficking of neutrophils to the inflammatory site ASC, apoptosis-associated...
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Báo cáo y học: "The biological and clinical importance of the ‘new generation’ cytokines in rheumatic diseases" pot
... enzyme (caspase-1) to generate a biologically active mature 18-kDa moiety [39,40] This cleavage takes place via inflammasome assembly and therefore cardinal, ASC, and NALP3 are implicated in IL-18 ... regulation Further studies implicate proteinase (PR3) as an extracellular-activating enzyme, whereas we recently observed that human neutrophil-derived serine proteases elastase and cathepsin G also ... define the biologic role and therefore therapeutic utility of this cytokine in pathology A further intriguing approach is to modulate the synthesis and release of IL-18 Whereas the inhibition of caspase-1...
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Báo cáo y học: "Developments in the scientific and clinical understanding of fibromyalgia" pdf
... hyperactivity and concomitantly reduced parasympathetic activity [50] The basal autonomic state of patients with FM was characterized by increased sympathetic and decreased parasympathetic tones in women ... disease and may be the source of many of the symptoms and much of the disability in these patients [25,26] Although FM is generally regarded as a noninflammatory and nonautoimmune disease, some patients ... fulfilled the 1990 ACR classification criteria for the diagnosis of FM [28] The authors have further reported that the prevalence of FM among blood relatives of patients with FM was 26%, and that the...
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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx
... Bein and colleagues [37] analyzed the impact of RMs on intracranial pressure and cerebral metabolism in patients with acute cerebral injury and respiratory failure, they observed an increase in ... cytoskeleton via the focal adhesion complex [11] When the basement membrane is strained, adherent epithelial cells must change shape and the ratio of their surface (plasma membrane) to their volume ... collapse lead to upregulation of an inflammatory response, with release of cytokines and chemokines and activation of neutrophils and macrophages that produce lung damage [2] Injurious MV can lead...
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Báo cáo y học: "Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis" pptx
... conduct of analyses, and in the clinical trials and data collection WLM, JJ, and DRN participated in the conception and design of the study, in the development and conduct of analyses, and in drafting ... the manuscript MDW participated in drafting the manuscript JFD participated in the clinical trials and data collection All authors contributed to the analysis and interpretation of the data and ... from an increase in the mortality rate for placebo patients, despite the absence of an increase in the APACHE II score as sites enrolled more patients There was not a parallel increase in mortality...
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