... pointes Unlikely Risk of liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of ... aberrations Of note, lithium in combination with angiotensin converting enzyme (ACE) inhibitors may produce an increased risk of arrhythmia [42,51] Valproate has an increased risk of liver injury in conjunction...
... for HIV uninfected individuals Certain areas of uncertainty remain, including the regimen duration, dosage and frequency of administration of anti-TB drugs, optimal timing of initiation of ART and ... from India compared the VOCs present in the urine of TB patients with VOCs in the urine of healthy subjects, and found that infection with TB produces a distinct pattern of certain VOCs in much ... feasibility of the WHO IPT guidelines in ART clinics as a precursor for adopting this recommendation77 Treatmentof individuals TB and HIV in co-infected The basic principles oftreatment for...
... M, Hemingway C, Scott G, Solomon T, Innes J British Infection Society guidelines for the diagnosis and treatmentoftuberculosisof the central nervous systemin adults and children J Infect ... imaging of the brain was also performed in a subset of patients in this study.36 It was found that use of corticosteroids possibly reduced the risk of developing hydrocephalus and vasculitic infarcts; ... Reversal of subclinical adrenal insufficiency through antituberculosis treatmentin TB patients: a longitudinal follow up Indian J Med Res 2005;122:127-31 30 Smego RA, Ahmed N A systematic review of...
... option since patients receiving olanzapine may require less psychiatric inpatient care In addition to having economic implications, the current findings are clinically meaningful to treatment ... all of which are linked to better long-term prognosis [24] The current findings are consistent with two previous randomized double-blind clinical studies of olanzapine and risperidone in the treatment ... who were continuously treated with the index drug during the year following initiation was aimed at avoiding the potential pitfalls associated with an intent-to-treat methodology in which all...
... prominence and influence in the network The aim of this study was to examine the connectedness in a newly established regional ParkinsonNet of health professionals involved in the treatmentof ... person was involved in professional contacts so far Knowing each other was defined in the questionnaire as ‘knowing the face, having talked to each with other, or having heard of. ’ Having professional ... reach in a specific number of steps in the network of in/ outgoing connections Betweenness centrality Number of pathways in the network in which an individual is in between’ of two other individuals...
... the findings can be explained using the link previously shown between longer treatment duration and better clinical efficacy in the treatmentof patients with schizophrenia [21,22,44-46] In meta-analytical ... Randomized, double-blind 6-month comparison of olanzapine and quetiapine in patients with schizophrenia or schizoaffective disorder with prominent negative symptoms and poor functioning J Clin Psychopharmacol ... Ascher-Svanum H: Meta-analysis oftreatment discontinuation for any cause comparing olanzapine and other antipsychotics in the treatmentof schizophrenia 15th Biennial Winter Workshop in Psychoses:15-18...
... techniques to the process of informing the selection of a cost effective treatment for children with ADHD in Spain Atomoxetine, a newly introduced treatment option in the Spanish market, was ... the time of waking The objective of the present study was to estimate the costeffectiveness of atomoxetine compared to MPH in the treatmentof children with ADHD As atomoxetine may offer a viable ... atomoxetine after a failure of an initial weeks treatmentwith XR-MPH in a randomised cross-over study of XR-MPH and atomoxetine [47] A probability of response on 'no medication' in Probabilities of...
... Bearing this in mind, the finding that only 8.0% of patients were prescribed clozapine can indicate a prescription rate of clozapine that was too low The finding of a rate of 6.5% discharges with ... in seven out of nine discharges with a comorbid mental retardation Bearing in mind that our data not provide information about treatment resistance, a reasonable interpretation of these findings ... [30] Nearly 5% of discharges have combinations of an SGA with clozapine, which could be in line with guideline recommendations in situations where clozapine monotherapy has been tried without success...
... Recombinant activated factor VIIa in an unselected series of cases with upper gastrointestinal bleeding Thromb Res 2005, Epub ahead of print 18 Rizoli SB, Chughtai T: The emerging role of recombinant ... multicenter survey of off-label use of rFVIIa in American academic hospitals [16], which reported that only 52% of the patients stopped bleeding within hours of rFVIIa administration and 9% suffered ... The role of recombinant factor VIIa in the treatmentof life-threatening haemorrhage in blunt trauma Injury 2005, 36:495-500 Boffard KD, Riou B, Warren B, Choong PI, Rizoli S, Rossaint R, Axelsen...
... degeneration in general, especially LBP, however overloading in the spine is the main cause of the pain - Characteristics of pain: The pain appears slowly, dull aching, increasing when working, when ... assessed treatment outcomes based on indicators of the degree of pain, the expansion of the lumbar spine and activity of the lumbar spine The results showed that after days oftreatmentwith 98.89% of ... harmony kidney Qi - Clinical applications: Shen Shu point is usually coordinated with other acupoint in the treatmentof diseases such as back pain, urinary system diseases, endocrine, reproductive,...
... determinants of parenting stress in mothers of children with CHD Social support explained 33.3% of parenting stress in this model, while social support and the source of information being the Internet ... of cues or vagueness of cues concerning the planning and carrying out of care for the child Lack of clarity refers to receiving or perceiving information about the child’s treatment and the system ... (b) examine the relationships among uncertainty, social support, and parenting stress in mothers of children with CHD, and (c) determine the factors affecting parenting stress in mothers of children...
... be administered within months of beginning treatment If treatment is not completed within this period, the patient should be assessed to determine the appropriate action to take—continuing treatment ... for infectious diseases Clin Infect Dis 1994;18:421 Geiter LJ, editor Ending neglect: the elimination oftuberculosisin the United States Institute of Medicine, Committee on Elimination ofTuberculosis ... obtained at the time of completion of months oftreatment is positive; patients whose initial phase oftreatment did not include PZA; and patients being treated with once weekly INH and rifapentine...
... conglutinin interact with this receptor, while binding could be inhibited using C1q and C1q collagen stalks, demonstrating that the collectin collagen domain is involved in receptor binding [56,213] ... collectin binding In several studies, the inability of collectins to bind to certain bacterial strains, correlated with increased pathogenicity [151] In addition, capsule production by bacteria is often ... GEKGEP motif within the collagen domain of MBL was shown to be involved in binding to the C1q receptor [54] Interestingly, the amino acid sequence of the collagen 1232 J K van de Wetering et al...
... procalcitonin and C-reactive protein levels as markers of bacterial B Usefulness of procalcitonin as a marker of systemic infection in infection: a systematic review and meta-analysis Clin Infect ... Journal of Internal Medicine Vol 24, No 4, December 2009 bacterial infection [15-18] Recently, PCT has also been introduced as a promising alternative to CRP in guiding the antibiotic treatmentof ... variable time interval from the onset of symptoms before evaluating PCT and CRP might have affected the results because of the kinetics of each inflammatory marker [29,30] Considering this point, a...
... aid in determining discriminant validity of the PedsQL™ Family Impact Module in our population of children with sickle cell disease, we collected data on the disease status of the children with ... convenience sample of parents of children with and without sickle cell disease at both clinics as part of a larger study of the HRQL of children [13,25] There were 145 parents of children with sickle ... parents of children with and without sickle cell disease In addition, we also compared parents of children with sickle cell disease to parents of children without sickle cell disease and without...
... were: MEDLINE via Pubmed (73), Web of Science (93) and PsycINFO (49) In accordance with the inclusion criteria, titles and abstracts of citations obtained from the search were examined independently ... of their role, lack of social and working support, course of the disease, and disruptions in family life All these factors were associated with a considerable damage of QOL The feeling of being ... [7-9] In 1993, The WHOQOL (The World Health Organization Quality of Life) Group [10] defined QOL as individuals' perceptions of their position in life in the context of the culture and value systems...
... controlled with local pressure and/or injection of thrombin Insertion of interventional sheaths in small arteries is associated with an increased risk of thrombosis Rapid heparinization after sheath insertion ... the incidence of CHS and of ICH in the largest series published before 2010, including series of patients undergoing angioplasty of intracranial arteries In order to document the incidence of ... those located within the brain, mainly the middle cerebral artery (MCA) In this chapter we will begin by discussing the pathophysiology, clinical presentation, and incidence of CHS in the different...
... less inflammation/joint destruction in DBA-lpr/ lpr mice in spite of the same clinical score as that of control mice The proinflammatory cytokines including TNF-α and IL-6 have been intensively investigated ... against CIA is not due to down-regulation of proinflammatory cytokines in joints Since cytokines such as TNF-α and IL-6 are critical mediators of inflammation, we investigated the effect of Fas ... inflammation; 1, swelling/redness of one joint; 2, swelling/redness of more than one joint or mild inflammation of the whole paw; 3, severe inflammation of whole paw or ankylosis For evaluating...
... cases with technical failure reported in 8% of cases and perforation in 4% [12] In this series the technique of stenting was introduced and developed in the unit during the study period and in the ... surgical intervention and stoma formation in patients presenting with malignant large bowel obstruction One of the concerns in managing patients with surgically incurable CRC without resection of the ... is an increased trend in the use of self expandable metallic stents (SEMS) A recent systematic review examined the role of SEMS in this situation and showed successful palliation in 90% of 336...
... and influx of inflammatory leukocytes is the hallmark of RA [4] The inflammatory synovial lining, especially the pannus tissue, resembles solid tumors in many ways, including the leaky nature of ... significantly less in the joints from animals treated with one injection of P-Dex compared with four injections of free Dex In the bones of the ankle joint, the BMD of the P-Dex group was not ... 13th day after arthritis induction, P-Dex (10 mg/kg, containing mg of Dex/10 mg P-Dex) was injected intravenously into one group of the RA rats An equivalent total dose of water-soluble free Dex...