stage 4 non small cell lung cancer spread to brain
Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... 70 343 1 94 340 60Age, yearsrange 36-85 42 -83 27-88median 64 67 59.9Sexmale 28 31 36female 50 30 34 EthnicityCaucasian 78 61 0 0 0Asian 0 0 70 343 60Smoking historysmokers 33 37 41 non- smokers ... Non- small- cell lung cancer harbouring mutations in the EGFRkinase domain. Clin Transl Oncol 2010, 12:75-80.9. Gazdar AF: Activating and resistance mutations of EGFR in non- small- cell lung cancer: ... epidermal growth factorreceptor mutation-specific antibodies for non- small cell lung cancer: immunohistochemistry as a possible screening method for epidermalgrowth factor receptor mutations. J...
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Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
... 65 2 47 161 48 0 31 172110 74 Tumor size (mm)Range (median) 12-55 (27) 12, 14 15- 34 ( 24) 31-55 (35)OperabilityOperable 40 2 27 11 Non- operable 84 0 58 26HistologyAdenocarcinoma 66 2 46 18Squamous ... 63: 142 7- 143 1.3. Onimaru R, Fujino M, Yamazaki K, Onodera Y, Taguchi H, Katoh N,Hommura F, Oizumi S, Nishimura M, Shirato H: Steep dose-responserelationship for stage I non- small- cell lung cancer ... of non- small- cell lung cancer. Int J Radiat Oncol Biol Phys 2002, 52:382-389.16. Qiao X, Tullgren O, Lax I, Sirzén F, Lewensohn R: The role of radiotherapyin treatment of stage I non- small cell...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... iotherapy, Oligometastases, Non- Small Cell Lung Cancer Background Non- small cell lung cancer (NSCLC) is the leadingcause of cancer mortality in the United States [1].Patients with stage IV NSCLC typically ... were a total of 94 patients ( 64. 3%) categorizedas stage III NSCLC, 38 patients (26.0%) with initial lim-ited stage IV NSCLC and 14 patients (9.6%) with stage I/II NSCLC who progressed to limited ... various stage groupings. The blue line represents Stage III (whomdid not progress to Stage IV, maroon line represents Stage III which progressed to Stage IV, green line represents the initial stage...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... schemeNone Minor None MinorSpinal Cord Any point 18 > 18 to 22 25 > 25 to 28Oesophagus 1 24 > 24 to 27 27 > 27 to 28.5Ipsilateral Brachial Plexus 1 24 > 24 to 26 27 > 27 to ... body radiotherapy for stage I non- small cell lung cancer. Radiother Oncol 2007, 85 :42 9 -43 4.39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat-eral primary lung cancers: the Indiana ... study wasperformed in 22 stage IA and 4 stage 1B non- small cell lung cancer patients in order to develop and evaluate theplanning guidelines differentiated according to type ofdose calculation...
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Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
... peripheral stage I non- small cell lung cancer. Lung Cancer 1999, 26:137- 142 .23. Slotman BJ, Antonisse IE, Njo KH: Limited field irradiation inearly stage (T1-2N0) non- small cell lung cancer. RadiotherOncol ... purposes)inoperable non- small cell lung cancer without mediastinalinvolvement (clinical stage N0, N1). Strahlenther Onkol 1996,172 :48 9 -49 5.22. Hayakawa K, Mitsuhashi N, Saito Y, et al.: Limited ... histologically confirmed non- small- cell bronchialcarcinomas < 5 cm with doses prescribed to the isocenterranging from 19 to 26 Gy. Under respiratory gating, Haraet al. [ 14] irradiated 23 lung...
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Báo cáo khoa học: " Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer" pot
... Symptoms only scoring used for late lung toxicity (modified from the Common Toxicity Criteria (CTC) version 2 – Lung) 012 345 No increase in lung symptomsIncrease in lung symptoms due to RT ... as lung cancer. It is more convenient for the patients and reduces health care costs.This study reports our results on patients with medically inoperable, early stage, non- small cell lung cancer ... stage group of patients; toxicity was evaluated retro-spectively and no severe grade 3 /4 toxicity was recorded.We did not use any special device to either decrease inspir-atory motion or to...
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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... (B).0 4 8 121620 242 8323 640 444 852Weeks00.20 .4 0.60.81TTPPatients Events (%)Arm A 35 33 ( 94. 3)Arm B 34 32 ( 94. 1)A0 4 8 12 16 20 24 28 32 36 40 44 48 52Weeks00.20 .4 0.60.81SurvivalPatients ... Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94: 153-156.2. Non- small Cell Lung Cancer Collaborative Group: Chemotherapyin non small cell lung cancer: a meta-analysis ... 14 (35) 12 (29.3)Other NSCLC 4 (10) 6 ( 14. 6)Site of disease Lung ± lymph nodes 14 (35) 14 ( 34. 1) Lung and 1 metastatic site 12 (30) 15 (36.6) Lung and ≥ 2 metastatic sites 9 (22.5) 10 ( 24. 4)Extra-pulmonary...
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... 138 41 47 47 Moderate 144 43 190 64 Well 53 16 NR 68Surgical procedure 0.0 04 Lobectomy + Wedge* 243 73 190 61Pneumonectomy 92 27 37 47 Pathological stage <0.001I 157 47 190 71II 136 41 ... marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6 649 -57. 24. World Health Organization: Histological Typing of Lung and PleuralTumours. ... in non- small cell lung cancer. Clin Cancer Res 2008, 14: 5220-7.30. Andersen S, Eilertsen M, Donnem T, et al: Diverging prognostic impacts ofhypoxic markers according to NSCLC histology. Lung Cancer...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... Staging of small cell and non- small cell lung cancer. University of Iowa Virtual Hos-pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat-ment in patients with lung cancer: ... Big Lung Trial in Non- Small- Cell Lung cancer. Journal of Clinical Oncology 2005, 30: 741 7- 742 7.12. Silvestri G, Pritchard R, Welch HG: Preferences for chemother-apy in patients with advanced non- small ... life-threatening form of cancer in Scot-land [2]. Lung cancer is also a major cause of deaththroughout the rest of the world [3 ,4] . Non- small cell lung cancer (NSCLC) has a poor progno-sis. On average,...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... sensitivity to gefitinib in non- small cell lung cancer cell lines. Mol Cancer Res. 2006; 4( 8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non- small- cell lung cancer ... growth factor receptor and non- small- cell lung cancer. J Med Genet. 2007; 44 (3): 166-72. 41 . Riely GJ, Pao W, Pham D, et al. Clinical course of patients with non- small cell lung cancer and ... 20 04; 305(5687): 1163-7. 31. Tracy S, Mukohara T, Hansen M, et al. Gefitinib induces apop-tosis in the EGFRL858R non- small- cell lung cancer cell line H3255. Cancer Res. 20 04; 64( 20): 7 241 -4. ...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... obtain a response after the first few cycles should notautomatically discourage to continue treatment.IntroductionIn non- small cell lung cancer (NSCLC), mediastinallymphnode involvement comprises ... 8:8http://www.wjso.com/content/8/1/8Page 3 of 4 CAS E REP O R T Open AccessPathological complete response induced byfirst-line chemotherapy with single agentdocetaxel in a patient with advanced non small cell lung cancer Ferdinando ... early stage disease to be cured with surgery and adjuvant therapy, as well. Aphase III trial randomized patients with stage IIIA orlocally treatable IIIB NSCLC to neoadjuvant docetaxel(up to...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... = 4. 64 0.011V40 8.20% (3.29-13.61%) = 5.91, SD = 2 .48 = 9.26, SD = 3.750.015V45 7 .42 % (2.73-10.99%) = 4. 41, SD = 2.25 = 6. 54, SD = 3 .47 0.007V50 7.07%(1. 94- 8.82%) = 3.15, SD = 1. 94 = 4. 89, ... = 2 .40 0.001V5 58.73% (32.89-97.65%) = 58 .43 , SD = 16.57 = 69.23, SD = 12 .47 0.006V10 42 .16%(25.28-83. 34% ) = 41 .13, SD = 12.69 = 52 .42 , SD = 11.050.001V15 29.53%(16 .46 -58.51%) = 28. 94, ... therapy for inoperable non- small cell lung cancer (NSCLC): Analysis of failures in a phase III study (RTOG 941 0) [Abstract]. Int J Radiat Oncol Biol Phys 2000, 48 :113. 4. Curran W, Scott C,...
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... of fail-ure for non- small- cell lung cancer with position-emissiontomography/computed tomography defined target delinea-tion. Int J Radiat Oncol Biol Phy 2007, 69: 140 9- 141 6. 14. Chang DT, Zlotecki ... international atomic energy agency (IAEA)consultants' meeting on elective nodal irradiation in lung cancer: non- small cell lung cancer (NSCLC). Int J Radiat OncolBiol Phys 2008, 72(2):335- 342 .6. ... for inperable stage III nons-mall cell lung cancer. AM J Clin Oncol 2007, 30:239- 244 .11. Bradley J, Graham MV, Winter K, Purdy JA, Komaki R, Roa WH, RyuJK, Bosch W, Emami B: Toxicity and outcome...
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Báo cáo khoa học: " Evalution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC)" pptx
... (years)Clinical T N stage Stage Histology Motion amplitude in SI direction (mm)GTV vol-ume in planning CT (cm3)Single dose (Gy)Total dose (Gy)Simultaneous chemotherapyPat #1 48 ,8 T4 N2 IIIB ... 62 DDP + NavelbinePat #5 49 ,0 T2 N2 IIIA Adeno Ca 11 147 .2 2 66 DDP + NavelbinePat #6 34, 9 T4 N2 IIIB Adeno Ca < 5 160.1 2 70 DDP + NavelbinePat #7 74, 2 T4 N2 IIIB Adeno Ca < 5 169.3 ... during exter-nal beam radiotherapy for non- small- cell lung cancer: obser-vations on tumor regression during treatment. Int J RadiatOncol Biol Phys 2005, 63:10 24- 1028.10. Yan D, Vicini F, Wong J,...
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Báo cáo khoa học: " Accelerated high-dose radiotherapy alone or combined with either concomitant or sequential chemotherapy; treatments of choice in patients with Non-Small Cell Lung Cancer" pps
... for stage I Nonsmall cell lung carcinoma. Cancer 20 04, 101:1623-1631. 54. Belderbos J, Heemsbergen W, Hoogeman M, Pengel K, Rossi M, Leb-esque J: Acute esophageal toxicity in non- small cell lung ... inpatients with locally advanced non- small- cell lung cancer. Aphase II trial conducted by the Groupe Francais de Pneumo-Cancerologie (GFPC). Lung Cancer 2005, 47 :395 -40 4. 42 . Vokes E, Herndon J, Kelley ... unresecta-ble stage IIIA and B non- small- cell lung cancer. J Clin Oncol2005, 23:3760-3767. 46 . El Sharouni SY, Kal HB, Battermann JJ: Accelerated regrowth of non- small- cell lung tumours after...
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