... participated inthe design and conduction ofthe study and drafted the manuscript PS participated inthe design ofthe study, performed the statistical analysis ofthe data and drafted the manuscript ... characteristics ofthepatientsand response to rituximab therapy The clinical and laboratory characteristics ofthe RA patients who were treated with rituximab are summarized in Table Patients had longstanding ... analysis of flow cytometry experiments HAP participated inthe design ofthe study and drafted the manuscript HK participated inthe design and conduction ofthe study, was involved in patient care and...
... enhancement, and vegetation, as well as being combined with AV damage The incidence of extended subvalvular chordae inthe myxomatous group was higher than that inthe other groups, andthe incidence of ... thickening combined with AV damage inthe CRV group was higher than that inthe other groups Infective endocarditis patients were younger than those inthe other groups, and there was a higher incidence ... shortening, and chordal transfer The methods of MV replacement included a mechanical prosthetic valve and bioprosthetic valve The method of choosing the type of surgical method depended on the location...
... ropivacaine and 20 ml 2% lignocaine was administered inthe recovery room prior to commencement of continuous infusion of 0.2% ropivacaine Intravenous PCA for both groups was inserted in theatre and ... analgesia and pain scores There was no significant difference inthe duration of PCA inthe CFNC and PCA only groups (Table 2) andthe amount of intravenous fentanyl used by both groups was compared There ... investigating the relationship between theuseof a CFNC and patient recovery in terms of their pain management, and functional mobility prior to discharge from hospital Both the CFNC andthe PCA...
... ropivacaine and 20 ml 2% lignocaine was administered inthe recovery room prior to commencement of continuous infusion of 0.2% ropivacaine Intravenous PCA for both groups was inserted in theatre and ... analgesia and pain scores There was no significant difference inthe duration of PCA inthe CFNC and PCA only groups (Table 2) andthe amount of intravenous fentanyl used by both groups was compared There ... investigating the relationship between theuseof a CFNC and patient recovery in terms of their pain management, and functional mobility prior to discharge from hospital Both the CFNC andthe PCA...
... population and who not have wasting muscle disease, smoking of any intensity has been implicated in muscle wasting [10] by impairing the process of muscle protein synthesis [46] In contrast, inthe ... assessments and participated inthe review ofthe manuscript YK participated inthe inception and development of protocol and served as PhD program supervisor GDK participated inthe inception and development ... regulates appetite [35] Smoking-induced increases inthe levels of epinephrine, norepinephrine, and thyroid hormones lead to increased energy expenditure at rest [36,37] and during light physical activity...
... associated with increase in plasma catecholamine levels or in biological markers of inflammatory response In spite of an increase in levels ofthe myocardial damage marker troponin T in 12 patients, ... dopamine in 11 patients, epinephrine in three patients, and norepinephrine in one patient during autonomic instability TNF-α levels Levels of TNF-α showed similar median plasma concentrations in ... elevation of troponin T in these patients Similarly, findings of increased troponins in sepsis have also been found to be associated with duration of hypotension, but not with areas of necrosis...
... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of ... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... pointes Unlikely Risk of liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases...
... Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts ofPatientswith Pulmonary Tuberculosis (such as uncle, grandfather, cousin) The definitions used for ... the number of male patients was higher inthe index cases, but the number of female patients was higher in contacts determined active disease In our opinion, the reason of this findings were that ... presence of cavity inthe chest radiograph of index case increased the frequency of TB in household contacts In our country, Kolsuz et al found the frequency of TB in close contact of TB cases...
... without the arcs ofthe inner rings, the length of missing radii was calculated as the difference between the bole geometric radius andthe total core length The number of missing rings was then ... the number of crossdated rings In partial cores, which contained the arcs ofthe Dendrochronology of oak: themanagement history 15 inner rings, the length of missing radii was calculated using ... based on the convergence of xylem rays at the pith [44] The number of missing rings was then estimated by extrapolating the radial growth rate from the innermost five rings inthe cores In partial...
... hospitalization during the treatment of adherent patientswith schizophrenia in usual care settings Patients who were newly initiated on olanzapine or risperidone and continued treatment withthe index antipsychotic ... risperidone on the same day Importantly, the inclusion ofpatients who were continuously treated withthe index drug during the year following initiation was aimed at avoiding the potential pitfalls ... defined as the number of days from initiation to the first hospitalization during the year post initiation Individuals who were inpatients at initiation and were not discharged from their index...
... reported the first systematic histological study of zygapophyseal joints inpatientswith AS [10] Inthe present study, we first examined whether inflammation inthe spine ofpatientswith AS, ... illustration ofthe anatomy and detection of inflammation inthe bone marrow The entire lumbar spine including the zygapophyseal joints and, if available, the thoracic spine was analyzed for increased ... highest score of bone marrow infiltation inthe histopathological assessment Some ofthepatients had inflammatory lesions in other parts ofthe spine, as indicated in Table Page of (page number...
... sustained The findings further indicate that theuseof US imaging ofthe foot would be more beneficial than clinical examination alone inthe refinement of diagnosis andthe implementation of ... beneficial in monitoring the progression of active inflammation in rheumatoid arthritis [13] andinthe monitoring of biologic therapy [14-16] The aim of this study was to evaluate by means of US, the ... regress within the forefeet In previous work, within the MCP joints ofthe hands a reduction in sonographically detectable synovial hypertrophy was noted at eighteen weeks following infliximab therapy,...
... differ These factors could influence the size ofthe impact ofthe intervention in other settings Limitations ofthe study The lack of randomization of clinics to intervention and control groups introduces ... intervention is in increasing the coverage ofthe offer of testing to 100% of new STI patients More than one-quarter ofpatients offered testing inthe intervention group declined to test (twice the proportion ... performance The increase in testing rate was achieved even though only 76% of all STI patientsinthe intervention clinics were offered testing One area for increasing the effectiveness ofthe PITC intervention...
... decision-making in scheduling ROEs Inthe second arm, the intervention focuses on monitoring and decision-making regarding prophylactic removal versus retention of MIM Groups of GDPs allocated to either ... largely independent of one another, i.e performing one would not necessarily influence the other Inthe ROE arm, the CPG only mentions the necessity of third molars screening in general as routine ... ofthe two intervention arms The baseline data collection will take place at the beginning ofthe study during months one and two The intervention will start in months two and three, and follow-up...
... differ These factors could influence the size ofthe impact ofthe intervention in other settings Limitations ofthe study The lack of randomization of clinics to intervention and control groups introduces ... intervention is in increasing the coverage ofthe offer of testing to 100% of new STI patients More than one-quarter ofpatients offered testing inthe intervention group declined to test (twice the proportion ... performance The increase in testing rate was achieved even though only 76% of all STI patientsinthe intervention clinics were offered testing One area for increasing the effectiveness ofthe PITC intervention...
... populations Inthe serum samples from patientswith SLE and RA used in this study, levels of BLyS, APRIL, and heterotrimer were elevated inpatientswith SLE, compared withthe sera of healthy donors The ... form of BLyS The molecular mass ofthe heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics ... determined from the kinetic rate constants (ka and kd) The binding curves were processed by double referencing and were globally fitted to a 1:1 binding model The stoichiometry of binding was...
... mRNA and protein levels This finding would open a new insight inthe field of monocyte-lineage cell biology andofthe diseases where this lineage cells play a prominent role Inthe latter part of ... collection and acquisition ofthe data and draft ofthe manuscript TA and TK was involved inthe interpretation and design ofthe study, and also drafted the manuscript All authors have read and approved ... macrophages, only one ofthe lung-derived dbESTs inthe data base originated from the hRasGRP4 gene In support of these dbEST data, the levels ofthe RasGRP4 transcript inthe mouse and human lung are...
... common inthe group whose position was varied than inthe group that remained continuously supine Con: prone positioning is not useful inthemanagementof ARDS patients Gordon Rubenfeld Imagine the ... another route to understanding this debate [14] At the heart of a discussion about theuseof prone ventilation (or of nitric oxide) is an understanding of how clinicians make decisions when the ... Finally, intensivists are strongly motivated by the ‘rule of rescue’ Intensivists feel obliged to offer some therapy, any therapy, to a patient in imminent danger of dying [16] As is often the...
... carcinoma cells were used as positive controls in this test [15] 1.0 μg of DNA (333 ng of PBMC DNA) was used inthe nested pol and gag PCR tests at the CDC for which 1,000 and 10 copies ofthe ... 43% Shows the number of states within the U.S that participants were recruited from, the average participant age, the average time since the onset of CFS symptoms, the race and gender of participants ... the right ofthe WB Sizes of expected viral proteins are provided to the left ofthe WB b Detection of XMRV antibodies in three experimentally-infected macaques (RII, RYh and RLq) Days post infection...
... P; and 23.4, 20.6, and 17.2 ml/kg PBW in group S The effect ofthe stepwise reduction in PEEP on the change in EELV in each patient inthe three study groups is shown in Figure Irrespective of ... carried out withthe COVX module (GE Healthcare, Helsinki, Finland) integrated within the ventilator This module was described in detail previously [9] At baseline, patients were switched to the Engström ... taken 10 minutes after the PEEP change and just before the EELV measurement to avoid any influence ofthe step change in Fio2 required for the nitrogen wash-out/washin test At the time ofthe EELV...